Taok1 (TAO kinase 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Taok1 (TAO kinase 1) Ictidomys tridecemlineatus
Analyze
Symbol: Taok1
Name: TAO kinase 1
RGD ID: 12480314
Description: ENCODES a protein that exhibits myosin V binding (ortholog); protein kinase activator activity (ortholog); protein kinase binding (ortholog); INVOLVED IN protein phosphorylation (ortholog); regulation of actin cytoskeleton organization (ortholog); regulation of microtubule cytoskeleton organization (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; ASSOCIATED WITH DEVELOPMENTAL DELAY WITH OR WITHOUT INTELLECTUAL IMPAIRMENT OR BEHAVIORAL ABNORMALITIES (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); microtubule cytoskeleton (inferred); perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase TAO1; TAO kinase 1, transcript variant X1; TAO kinase 1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Taok1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAOK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381729,390,363 - 29,551,903 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1729,390,363 - 29,551,903 (+)EnsemblGRCh38hg38GRCh38
GRCh371727,717,381 - 27,878,921 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,742,069 - 24,895,628 (+)NCBINCBI36Build 36hg18NCBI36
Build 341724,742,068 - 24,895,628NCBI
Celera1724,578,467 - 24,732,052 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,926,953 - 24,088,276 (+)NCBIHuRef
CHM1_11727,780,525 - 27,941,583 (+)NCBICHM1_1
T2T-CHM13v2.01730,333,099 - 30,494,790 (+)NCBIT2T-CHM13v2.0
Taok1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,419,988 - 77,516,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,419,988 - 77,498,641 (-)EnsemblGRCm39 Ensembl
GRCm381177,529,162 - 77,625,359 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,529,162 - 77,607,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,342,664 - 77,421,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,345,008 - 77,441,517 (-)NCBIMGSCv36mm8
Celera1185,027,723 - 85,106,434 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.64NCBI
Taok1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81062,871,198 - 62,989,049 (-)NCBIGRCr8
mRatBN7.21062,373,072 - 62,465,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1062,381,404 - 62,465,766 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,022,606 - 67,114,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01066,528,092 - 66,619,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,001,615 - 62,093,549 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,542,870 - 62,630,341 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,566,732 - 62,630,155 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01062,248,005 - 62,327,224 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41066,503,966 - 66,584,625 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11066,548,175 - 66,598,248 (+)NCBI
Celera1061,384,884 - 61,459,425 (-)NCBICelera
Cytogenetic Map10q24NCBI
Taok1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,705,202 - 3,772,116 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,698,686 - 3,836,209 (-)NCBIChiLan1.0ChiLan1.0
TAOK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21934,904,479 - 35,068,996 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11736,786,783 - 36,949,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01727,222,725 - 27,385,713 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11727,737,904 - 27,898,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1727,746,797 - 27,840,623 (-)Ensemblpanpan1.1panPan2
TAOK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,501,752 - 43,660,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,559,708 - 43,651,377 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,655,335 - 42,813,192 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0944,317,884 - 44,476,267 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl944,317,346 - 44,468,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1943,101,849 - 43,260,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0943,392,920 - 43,551,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0943,473,077 - 43,631,426 (+)NCBIUU_Cfam_GSD_1.0
TAOK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,597,072 - 45,744,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,597,067 - 45,750,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,551,021 - 47,697,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAOK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,145,629 - 23,291,694 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660756,780,705 - 6,950,118 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taok1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,968,991 - 2,045,948 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,920,037 - 2,054,795 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000014282   ⟹   ENSSTOP00000012791
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)Ensembl
RefSeq Acc Id: XM_005327853   ⟹   XP_005327910
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBI
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005726458
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560242,653,688 - 42,780,968 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005327910 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012791.3
GenBank Protein KAG3269658 (Get FASTA)   NCBI Sequence Viewer  
  KAG3269659 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005327910   ⟸   XM_005327853
- UniProtKB: I3MMM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000012791   ⟸   ENSSTOT00000014282
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014276 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014282.3 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Taok1 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE TAO1 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt I3MMM1 ENTREZGENE, UniProtKB/TrEMBL