Taok1 (TAO kinase 1) - Rat Genome Database

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Gene: Taok1 (TAO kinase 1) Ictidomys tridecemlineatus
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Symbol: Taok1
Name: TAO kinase 1
RGD ID: 12480314
Description: ENCODES a protein that exhibits myosin V binding (ortholog); protein kinase activator activity (ortholog); protein kinase binding (ortholog); INVOLVED IN phosphorylation (ortholog); protein autophosphorylation (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 1 (ortholog); DEVELOPMENTAL DELAY WITH OR WITHOUT INTELLECTUAL IMPAIRMENT OR BEHAVIORAL ABNORMALITIES (ortholog); Developmental Disabilities (ortholog); FOUND IN cytoplasm (inferred); microtubule cytoskeleton (inferred); perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: serine/threonine-protein kinase TAO1; TAO kinase 1, transcript variant X1; TAO kinase 1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Taok1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAOK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381729,390,363 - 29,551,903 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1729,390,363 - 29,551,903 (+)EnsemblGRCh38hg38GRCh38
GRCh371727,717,381 - 27,878,921 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361724,742,069 - 24,895,628 (+)NCBINCBI36Build 36hg18NCBI36
Build 341724,742,068 - 24,895,628NCBI
Celera1724,578,467 - 24,732,052 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,926,953 - 24,088,276 (+)NCBIHuRef
CHM1_11727,780,525 - 27,941,583 (+)NCBICHM1_1
T2T-CHM13v2.01730,333,099 - 30,494,790 (+)NCBIT2T-CHM13v2.0
Taok1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391177,419,988 - 77,516,185 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1177,419,988 - 77,498,641 (-)EnsemblGRCm39 Ensembl
GRCm381177,529,162 - 77,625,359 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1177,529,162 - 77,607,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv371177,342,664 - 77,421,317 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361177,345,008 - 77,441,517 (-)NCBIMGSCv36mm8
Celera1185,027,723 - 85,106,434 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.64NCBI
Taok1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81062,871,198 - 62,989,049 (-)NCBIGRCr8
mRatBN7.21062,373,072 - 62,465,295 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1062,381,404 - 62,465,766 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,022,606 - 67,114,241 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01066,528,092 - 66,619,731 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,001,615 - 62,093,549 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01062,542,870 - 62,630,341 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1062,566,732 - 62,630,155 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01062,248,005 - 62,327,224 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41066,503,966 - 66,584,625 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11066,548,175 - 66,598,248 (+)NCBI
Celera1061,384,884 - 61,459,425 (-)NCBICelera
Cytogenetic Map10q24NCBI
Taok1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554813,705,202 - 3,772,116 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554813,698,686 - 3,836,209 (-)NCBIChiLan1.0ChiLan1.0
TAOK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21934,904,479 - 35,068,996 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11736,786,783 - 36,949,382 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01727,222,725 - 27,385,713 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11727,737,904 - 27,898,436 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1727,746,797 - 27,840,623 (-)Ensemblpanpan1.1panPan2
TAOK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1943,501,752 - 43,660,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl943,559,708 - 43,651,377 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha942,655,335 - 42,813,192 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0944,317,884 - 44,476,267 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl944,317,346 - 44,468,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1943,101,849 - 43,260,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0943,392,920 - 43,551,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0943,473,077 - 43,631,426 (+)NCBIUU_Cfam_GSD_1.0
TAOK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1245,597,072 - 45,744,356 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11245,597,067 - 45,750,117 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21247,551,021 - 47,697,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAOK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11623,145,629 - 23,291,694 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660756,780,705 - 6,950,118 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taok1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,968,991 - 2,045,948 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,920,037 - 2,054,795 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000014282   ⟹   ENSSTOP00000012791
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365385,531,633 - 5,659,239 (+)Ensembl
RefSeq Acc Id: XM_005327853   ⟹   XP_005327910
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560242,653,688 - 42,790,172 (+)NCBI
SpeTri2.0NW_0049365385,531,639 - 5,668,119 (+)NCBI
Sequence:
RefSeq Acc Id: XR_005726458
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560242,653,688 - 42,780,968 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005327910 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000012791.3
GenBank Protein KAG3269658 (Get FASTA)   NCBI Sequence Viewer  
  KAG3269659 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005327910   ⟸   XM_005327853
- UniProtKB: I3MMM1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000012791   ⟸   ENSSTOT00000014282
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014276 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000014282.3 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  TAO_STE20_kinase UniProtKB/TrEMBL
NCBI Gene Taok1 ENTREZGENE
PANTHER SERINE/THREONINE-PROTEIN KINASE TAO1 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE TAO1-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt I3MMM1 ENTREZGENE, UniProtKB/TrEMBL