ZNF689 (zinc finger protein 689) - Rat Genome Database

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Gene: ZNF689 (zinc finger protein 689) Canis lupus familiaris
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Symbol: ZNF689
Name: zinc finger protein 689
RGD ID: 12429109
Description: ENCODES a protein that exhibits histone binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); skeletal muscle cell differentiation (ortholog); ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC489910
RGD Orthologs
Human
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,552,119 - 17,557,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,540,075 - 17,591,092 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,125,900 - 19,133,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,683,006 - 17,690,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,671,556 - 17,722,463 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,483,183 - 17,490,514 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,398,250 - 17,405,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,713,485 - 17,720,817 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
ZNF689
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,552,119 - 17,557,077 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,540,075 - 17,591,092 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,125,900 - 19,133,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,683,006 - 17,690,337 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,671,556 - 17,722,463 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,483,183 - 17,490,514 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,398,250 - 17,405,582 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,713,485 - 17,720,817 (+)NCBIUU_Cfam_GSD_1.0
ZNF689
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,602,558 - 30,610,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,602,558 - 30,624,012 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,613,879 - 30,622,096 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,522,187 - 30,529,183 (-)NCBINCBI36Build 36hg18NCBI36
Celera1629,676,732 - 29,683,727 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1628,177,463 - 28,185,679 (-)NCBIHuRef
CHM1_11631,931,058 - 31,939,273 (-)NCBICHM1_1
T2T-CHM13v2.01630,989,540 - 30,997,757 (-)NCBIT2T-CHM13v2.0

Variants

.
Variants in ZNF689
26 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00000026312   ⟹   ENSCAFP00000024436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,540,075 - 17,557,090 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000048969   ⟹   ENSCAFP00000039560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,540,075 - 17,579,555 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000061707   ⟹   ENSCAFP00000054717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,540,075 - 17,557,090 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000062660   ⟹   ENSCAFP00000049491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,577,486 - 17,591,092 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000076138   ⟹   ENSCAFP00000066348
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,577,486 - 17,591,092 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000079362   ⟹   ENSCAFP00000043277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,540,075 - 17,591,092 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000080039   ⟹   ENSCAFP00000059762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,552,291 - 17,557,090 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000083243   ⟹   ENSCAFP00000064727
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,588,855 - 17,591,092 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000085219   ⟹   ENSCAFP00000057419
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl617,552,291 - 17,591,092 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024558   ⟹   ENSCAFP00845019317
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,671,556 - 17,711,010 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024566   ⟹   ENSCAFP00845019325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,671,556 - 17,690,241 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024576   ⟹   ENSCAFP00845019333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,683,368 - 17,690,241 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024605   ⟹   ENSCAFP00845019355
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,683,689 - 17,722,463 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024610   ⟹   ENSCAFP00845019357
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,683,689 - 17,711,149 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024617   ⟹   ENSCAFP00845019363
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,683,689 - 17,711,010 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024628   ⟹   ENSCAFP00845019373
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,696,875 - 17,711,010 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024643   ⟹   ENSCAFP00845019387
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,708,434 - 17,711,010 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024656   ⟹   ENSCAFP00845019401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,708,681 - 17,722,463 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845024667   ⟹   ENSCAFP00845019412
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl617,720,116 - 17,722,463 (+)Ensembl
RefSeq Acc Id: XM_038478559   ⟹   XP_038334487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1617,483,183 - 17,490,514 (+)NCBI
RefSeq Acc Id: XM_038539808   ⟹   XP_038395736
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0617,713,485 - 17,720,817 (+)NCBI
RefSeq Acc Id: XM_038603888   ⟹   XP_038459816
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0617,398,250 - 17,405,582 (+)NCBI
RefSeq Acc Id: XM_038668612   ⟹   XP_038524540
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0617,683,006 - 17,690,337 (+)NCBI
RefSeq Acc Id: XM_547029   ⟹   XP_547029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1617,552,119 - 17,557,077 (+)NCBI
Dog10K_Boxer_Tasha619,125,900 - 19,133,232 (+)NCBI
Sequence:
RefSeq Acc Id: XP_547029   ⟸   XM_547029
- UniProtKB: A0A8C0KZI0 (UniProtKB/TrEMBL),   A0A8C0M9P4 (UniProtKB/TrEMBL),   A0A8I3NTT4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000059762   ⟸   ENSCAFT00000080039
Ensembl Acc Id: ENSCAFP00000043277   ⟸   ENSCAFT00000079362
Ensembl Acc Id: ENSCAFP00000064727   ⟸   ENSCAFT00000083243
Ensembl Acc Id: ENSCAFP00000039560   ⟸   ENSCAFT00000048969
Ensembl Acc Id: ENSCAFP00000066348   ⟸   ENSCAFT00000076138
Ensembl Acc Id: ENSCAFP00000049491   ⟸   ENSCAFT00000062660
Ensembl Acc Id: ENSCAFP00000024436   ⟸   ENSCAFT00000026312
Ensembl Acc Id: ENSCAFP00000057419   ⟸   ENSCAFT00000085219
Ensembl Acc Id: ENSCAFP00000054717   ⟸   ENSCAFT00000061707
RefSeq Acc Id: XP_038334487   ⟸   XM_038478559
RefSeq Acc Id: XP_038459816   ⟸   XM_038603888
RefSeq Acc Id: XP_038524540   ⟸   XM_038668612
- UniProtKB: A0A8C0KZI0 (UniProtKB/TrEMBL),   A0A8C0M9P4 (UniProtKB/TrEMBL),   A0A8I3NTT4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395736   ⟸   XM_038539808
- UniProtKB: A0A8C0KZI0 (UniProtKB/TrEMBL),   A0A8C0M9P4 (UniProtKB/TrEMBL),   A0A8I3NTT4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845019387   ⟸   ENSCAFT00845024643
Ensembl Acc Id: ENSCAFP00845019317   ⟸   ENSCAFT00845024558
Ensembl Acc Id: ENSCAFP00845019333   ⟸   ENSCAFT00845024576
Ensembl Acc Id: ENSCAFP00845019401   ⟸   ENSCAFT00845024656
Ensembl Acc Id: ENSCAFP00845019373   ⟸   ENSCAFT00845024628
Ensembl Acc Id: ENSCAFP00845019363   ⟸   ENSCAFT00845024617
Ensembl Acc Id: ENSCAFP00845019412   ⟸   ENSCAFT00845024667
Ensembl Acc Id: ENSCAFP00845019357   ⟸   ENSCAFT00845024610
Ensembl Acc Id: ENSCAFP00845019355   ⟸   ENSCAFT00845024605
Ensembl Acc Id: ENSCAFP00845019325   ⟸   ENSCAFT00845024566
Protein Domains
C2H2-type   KRAB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016625 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002445 UniProtKB/TrEMBL
  ENSCAFG00040013569 UniProtKB/TrEMBL
  ENSCAFG00845013768 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026312.5 UniProtKB/TrEMBL
  ENSCAFT00000048969.3 UniProtKB/TrEMBL
  ENSCAFT00000062660.2 UniProtKB/TrEMBL
  ENSCAFT00000079362.2 UniProtKB/TrEMBL
  ENSCAFT00000080039.2 UniProtKB/TrEMBL
  ENSCAFT00000083243.2 UniProtKB/TrEMBL
  ENSCAFT00000085219.2 UniProtKB/TrEMBL
  ENSCAFT00000106955.1 UniProtKB/TrEMBL
  ENSCAFT00030004511.1 UniProtKB/TrEMBL
  ENSCAFT00030004530.1 UniProtKB/TrEMBL
  ENSCAFT00030004546.1 UniProtKB/TrEMBL
  ENSCAFT00030004552.1 UniProtKB/TrEMBL
  ENSCAFT00030004560.1 UniProtKB/TrEMBL
  ENSCAFT00030004570.1 UniProtKB/TrEMBL
  ENSCAFT00040025032.1 UniProtKB/TrEMBL
  ENSCAFT00040025058.1 UniProtKB/TrEMBL
  ENSCAFT00040025101.1 UniProtKB/TrEMBL
  ENSCAFT00040025152.1 UniProtKB/TrEMBL
  ENSCAFT00040025216.1 UniProtKB/TrEMBL
  ENSCAFT00040025246.1 UniProtKB/TrEMBL
  ENSCAFT00040025275.1 UniProtKB/TrEMBL
  ENSCAFT00845024558.1 UniProtKB/TrEMBL
  ENSCAFT00845024566.1 UniProtKB/TrEMBL
  ENSCAFT00845024576 ENTREZGENE
  ENSCAFT00845024576.1 UniProtKB/TrEMBL
  ENSCAFT00845024605.1 UniProtKB/TrEMBL
  ENSCAFT00845024610.1 UniProtKB/TrEMBL
  ENSCAFT00845024617.1 UniProtKB/TrEMBL
  ENSCAFT00845024628.1 UniProtKB/TrEMBL
  ENSCAFT00845024643.1 UniProtKB/TrEMBL
  ENSCAFT00845024656.1 UniProtKB/TrEMBL
  ENSCAFT00845024667.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro C2H2-ZF_domain UniProtKB/TrEMBL
  KRAB UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel_C2H2_ZnF UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
KEGG Report cfa:489910 UniProtKB/TrEMBL
NCBI Gene ZNF689 ENTREZGENE
PANTHER FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED UniProtKB/TrEMBL
  KRAB DOMAIN C2H2 ZINC FINGER UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 628 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 688 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 747 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 771 UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF109640 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0KZI0 ENTREZGENE
  A0A8C0LZI5_CANLF UniProtKB/TrEMBL
  A0A8C0M2Q5_CANLF UniProtKB/TrEMBL
  A0A8C0M4Z9_CANLF UniProtKB/TrEMBL
  A0A8C0M507_CANLF UniProtKB/TrEMBL
  A0A8C0M519_CANLF UniProtKB/TrEMBL
  A0A8C0M9P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SHU8_CANLF UniProtKB/TrEMBL
  A0A8C0SIJ5_CANLF UniProtKB/TrEMBL
  A0A8I3NFK4_CANLF UniProtKB/TrEMBL
  A0A8I3NFN4_CANLF UniProtKB/TrEMBL
  A0A8I3NN78_CANLF UniProtKB/TrEMBL
  A0A8I3NS52_CANLF UniProtKB/TrEMBL
  A0A8I3NTN2_CANLF UniProtKB/TrEMBL
  A0A8I3NTQ4_CANLF UniProtKB/TrEMBL
  A0A8I3NTT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NTV4_CANLF UniProtKB/TrEMBL
  A0A8I3RXQ2_CANLF UniProtKB/TrEMBL
  A0A8I3S0D7_CANLF UniProtKB/TrEMBL
  A0A8P0NZI0_CANLF UniProtKB/TrEMBL
  A0A8P0PDE5_CANLF UniProtKB/TrEMBL
  A0A8P0SWN4_CANLF UniProtKB/TrEMBL
  A0A8P0T9F4_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0PL74 UniProtKB/TrEMBL
VGNC ID VGNC:54098 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-10 ZNF689  zinc finger protein 689  LOC489910    Symbol and/or name change 5135510 APPROVED
2017-09-12 LOC489910  zinc finger protein 689  ZNF689    Symbol and/or name change 5135510 APPROVED