TRPC4AP (transient receptor potential cation channel subfamily C member 4 associated protein) - Rat Genome Database

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Gene: TRPC4AP (transient receptor potential cation channel subfamily C member 4 associated protein) Canis lupus familiaris
Analyze
Symbol: TRPC4AP
Name: transient receptor potential cation channel subfamily C member 4 associated protein
RGD ID: 12384831
Description: ENCODES a protein that exhibits phosphatase binding (inferred); ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN hair follicle maturation (ortholog); ASSOCIATED WITH glutathione synthetase deficiency (ortholog); glutatione synthetase deficiency with 5-oxoprolinuria (ortholog); long QT syndrome (ortholog); FOUND IN Cul4-RING E3 ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: short transient receptor potential channel 4-associated protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12424,041,023 - 24,109,927 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2424,041,550 - 24,109,904 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,687,058 - 23,756,260 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,732,981 - 24,802,322 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,732,983 - 24,802,208 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12424,020,060 - 24,089,441 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02424,115,489 - 24,184,767 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,554,407 - 24,623,463 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TRPC4AP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12424,041,023 - 24,109,927 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2424,041,550 - 24,109,904 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2423,687,058 - 23,756,260 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02424,732,981 - 24,802,322 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2424,732,983 - 24,802,208 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12424,020,060 - 24,089,441 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02424,115,489 - 24,184,767 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02424,554,407 - 24,623,463 (-)NCBIUU_Cfam_GSD_1.0
TRPC4AP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382035,002,404 - 35,092,807 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2035,002,404 - 35,092,807 (-)EnsemblGRCh38hg38GRCh38
GRCh372033,590,207 - 33,680,610 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362033,053,868 - 33,144,279 (-)NCBINCBI36Build 36hg18NCBI36
Celera2030,339,293 - 30,429,447 (-)NCBICelera
Cytogenetic Map20q11.22NCBI
HuRef2030,368,536 - 30,458,590 (-)NCBIHuRef
CHM1_12033,491,389 - 33,581,552 (-)NCBICHM1_1
T2T-CHM13v2.02036,717,007 - 36,813,143 (-)NCBIT2T-CHM13v2.0
Trpc4ap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392155,476,197 - 155,534,304 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2155,476,191 - 155,534,304 (-)EnsemblGRCm39 Ensembl
GRCm382155,634,277 - 155,692,384 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2155,634,271 - 155,692,384 (-)EnsemblGRCm38mm10GRCm38
MGSCv372155,460,013 - 155,518,120 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362155,325,749 - 155,383,773 (-)NCBIMGSCv36mm8
Celera2161,566,542 - 161,624,663 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map277.26NCBI
Trpc4ap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83164,582,146 - 164,653,123 (-)NCBIGRCr8
mRatBN7.23144,122,003 - 144,192,986 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3144,122,003 - 144,192,986 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3147,988,304 - 148,059,284 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03156,605,584 - 156,676,566 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03154,345,122 - 154,416,061 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03151,150,396 - 151,224,123 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3151,150,396 - 151,224,123 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03157,518,203 - 157,588,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43146,139,493 - 146,206,625 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13146,045,105 - 146,112,244 (-)NCBI
Celera3142,846,195 - 142,917,255 (-)NCBICelera
Cytogenetic Map3q42NCBI
Trpc4ap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542226,301,464 - 26,386,007 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542226,301,937 - 26,383,464 (+)NCBIChiLan1.0ChiLan1.0
TRPC4AP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22140,735,344 - 40,826,296 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12040,728,447 - 40,819,400 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02031,330,860 - 31,420,662 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12032,455,536 - 32,545,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2032,455,536 - 32,545,780 (-)Ensemblpanpan1.1panPan2
Trpc4ap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640173,028,172 - 173,107,284 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365615,642,249 - 5,721,377 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365615,642,265 - 5,721,377 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPC4AP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1738,385,653 - 38,468,295 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11738,385,650 - 38,468,290 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21743,582,681 - 43,665,530 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRPC4AP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1239,304,240 - 39,391,447 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl239,305,203 - 39,391,418 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,420,710 - 87,508,627 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trpc4ap
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248424,316,578 - 4,395,792 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248424,317,710 - 4,395,792 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TRPC4AP
749 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000012642   ⟹   ENSCAFP00000011709
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2424,041,550 - 24,109,904 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000044637   ⟹   ENSCAFP00000041702
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2424,041,550 - 24,109,904 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032376   ⟹   ENSCAFP00845025307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2424,732,983 - 24,802,208 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032521   ⟹   ENSCAFP00845025432
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2424,732,983 - 24,802,208 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845032672   ⟹   ENSCAFP00845025556
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2424,732,984 - 24,802,136 (-)Ensembl
RefSeq Acc Id: XM_005634965   ⟹   XP_005635022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12424,041,023 - 24,109,927 (-)NCBI
Dog10K_Boxer_Tasha2423,687,058 - 23,756,074 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038433599   ⟹   XP_038289527
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02424,732,981 - 24,802,136 (-)NCBI
RefSeq Acc Id: XM_038433600   ⟹   XP_038289528
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02424,732,981 - 24,802,322 (-)NCBI
RefSeq Acc Id: XM_038508776   ⟹   XP_038364704
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12424,020,060 - 24,089,255 (-)NCBI
RefSeq Acc Id: XM_038508777   ⟹   XP_038364705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12424,020,060 - 24,089,441 (-)NCBI
RefSeq Acc Id: XM_038572089   ⟹   XP_038428017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02424,554,407 - 24,623,277 (-)NCBI
RefSeq Acc Id: XM_038572091   ⟹   XP_038428019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02424,554,407 - 24,623,463 (-)NCBI
RefSeq Acc Id: XM_038636342   ⟹   XP_038492270
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02424,115,489 - 24,184,581 (-)NCBI
RefSeq Acc Id: XM_038636343   ⟹   XP_038492271
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02424,115,489 - 24,184,767 (-)NCBI
RefSeq Acc Id: XM_846577   ⟹   XP_851670
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12424,041,023 - 24,109,925 (-)NCBI
Dog10K_Boxer_Tasha2423,687,058 - 23,756,260 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005635022   ⟸   XM_005634965
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_851670   ⟸   XM_846577
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX97 (UniProtKB/TrEMBL),   A0A8C0PH97 (UniProtKB/TrEMBL),   A0A8I3S366 (UniProtKB/TrEMBL),   A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000041702   ⟸   ENSCAFT00000044637
Ensembl Acc Id: ENSCAFP00000011709   ⟸   ENSCAFT00000012642
RefSeq Acc Id: XP_038364705   ⟸   XM_038508777
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038364704   ⟸   XM_038508776
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492271   ⟸   XM_038636343
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492270   ⟸   XM_038636342
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038289528   ⟸   XM_038433600
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX97 (UniProtKB/TrEMBL),   A0A8C0PH97 (UniProtKB/TrEMBL),   A0A8I3S366 (UniProtKB/TrEMBL),   A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038289527   ⟸   XM_038433599
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428019   ⟸   XM_038572091
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX97 (UniProtKB/TrEMBL),   A0A8C0PH97 (UniProtKB/TrEMBL),   A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8I3S366 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038428017   ⟸   XM_038572089
- Peptide Label: isoform X1
- UniProtKB: A0A8I3P6L7 (UniProtKB/TrEMBL),   A0A8P0NSJ3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845025432   ⟸   ENSCAFT00845032521
Ensembl Acc Id: ENSCAFP00845025556   ⟸   ENSCAFT00845032672
Ensembl Acc Id: ENSCAFP00845025307   ⟸   ENSCAFT00845032376

Promoters
RGD ID:13687588
Promoter ID:EPDNEW_C5656
Type:multiple initiation site
Name:TRPC4AP_1
Description:transient receptor potential cation channel subfamily C member4 associated protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12424,109,918 - 24,109,978EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007912 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021856 UniProtKB/TrEMBL
  ENSCAFG00040007631 UniProtKB/TrEMBL
  ENSCAFG00845018297 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012642.6 UniProtKB/TrEMBL
  ENSCAFT00000044637.4 UniProtKB/TrEMBL
  ENSCAFT00030040116.1 UniProtKB/TrEMBL
  ENSCAFT00030040195.1 UniProtKB/TrEMBL
  ENSCAFT00040014221.1 UniProtKB/TrEMBL
  ENSCAFT00845032376 ENTREZGENE
  ENSCAFT00845032376.1 UniProtKB/TrEMBL
  ENSCAFT00845032521.1 UniProtKB/TrEMBL
  ENSCAFT00845032672.1 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  TRPC4AP UniProtKB/TrEMBL
NCBI Gene TRPC4AP ENTREZGENE
PANTHER PTHR31743 UniProtKB/TrEMBL
  SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN UniProtKB/TrEMBL
Pfam DUF3689 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0JX97 ENTREZGENE
  A0A8C0PDH1_CANLF UniProtKB/TrEMBL
  A0A8C0PH97 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P6L7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P713_CANLF UniProtKB/TrEMBL
  A0A8I3S366 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NSJ3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:47869 ENTREZGENE