CBD108 (beta-defensin 108B) - Rat Genome Database

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Gene: CBD108 (beta-defensin 108B) Canis lupus familiaris
Analyze
Symbol: CBD108
Name: beta-defensin 108B
RGD ID: 12377699
Description: INVOLVED IN defense response to bacterium (inferred); innate immune response (inferred); ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); cerebral folate receptor alpha deficiency (ortholog); intellectual disability (ortholog); FOUND IN extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-defensin 108; uncharacterized CBD108; uncharacterized protein CBD108
RGD Orthologs
Human
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11653,938,211 - 53,944,168 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1649,441,883 - 49,447,847 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01656,252,463 - 56,258,418 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11654,146,923 - 54,152,897 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01654,743,868 - 54,749,848 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01654,979,194 - 54,985,176 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16033865   PMID:22301074  


Genomics

Comparative Map Data
CBD108
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11653,938,211 - 53,944,168 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1649,441,883 - 49,447,847 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01656,252,463 - 56,258,418 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11654,146,923 - 54,152,897 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01654,743,868 - 54,749,848 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01654,979,194 - 54,985,176 (-)NCBIUU_Cfam_GSD_1.0
DEFB108B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381171,833,200 - 71,837,710 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1171,833,200 - 71,837,710 (+)EnsemblGRCh38hg38GRCh38
GRCh371171,544,246 - 71,548,756 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361171,221,894 - 71,226,256 (+)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map11q13.4NCBI
HuRef1167,838,193 - 67,842,396 (+)NCBIHuRef
CHM1_11171,428,153 - 71,432,511 (+)NCBICHM1_1
T2T-CHM13v2.01171,760,109 - 71,764,619 (+)NCBIT2T-CHM13v2.0
DEFB108B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2972,771,620 - 72,780,580 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11173,813,935 - 73,822,771 (+)NCBINHGRI_mPanPan1
DEFB108B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366605235,358,064 - 35,362,339 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CBD108
118 total Variants

Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003432123   ⟹   XP_003432171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11653,938,211 - 53,944,168 (-)NCBI
Dog10K_Boxer_Tasha1649,441,883 - 49,447,847 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038498031   ⟹   XP_038353959
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11654,146,923 - 54,152,897 (-)NCBI
RefSeq Acc Id: XM_038560518   ⟹   XP_038416446
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01654,979,194 - 54,985,176 (-)NCBI
RefSeq Acc Id: XM_038624558   ⟹   XP_038480486
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01654,743,868 - 54,749,848 (-)NCBI
RefSeq Acc Id: XM_038690335   ⟹   XP_038546263
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01656,252,463 - 56,258,418 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003432171 (Get FASTA)   NCBI Sequence Viewer  
  XP_038353959 (Get FASTA)   NCBI Sequence Viewer  
  XP_038416446 (Get FASTA)   NCBI Sequence Viewer  
  XP_038480486 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546263 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAY59715 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000063398.1
RefSeq Acc Id: XP_003432171   ⟸   XM_003432123
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LAB6 (UniProtKB/TrEMBL),   A0A8P0TEY5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038353959   ⟸   XM_038498031
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038480486   ⟸   XM_038624558
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038546263   ⟸   XM_038690335
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LAB6 (UniProtKB/TrEMBL),   A0A8P0TEY5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416446   ⟸   XM_038560518
- Peptide Label: isoform X4
- UniProtKB: Q30KU5 (UniProtKB/TrEMBL)
Protein Domains
Beta-defensin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000043922 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000071072.2 UniProtKB/TrEMBL
InterPro Beta_defensin UniProtKB/TrEMBL
KEGG Report cfa:100686479 UniProtKB/TrEMBL
NCBI Gene CBD108 ENTREZGENE
Pfam Defensin_beta_2 UniProtKB/TrEMBL
UniProt A0A8C0LAB6 ENTREZGENE
  A0A8P0TEY5 ENTREZGENE, UniProtKB/TrEMBL
  Q30KU5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 CBD108  beta-defensin 108B  CBD108  uncharacterized CBD108  Symbol and/or name change 5135510 APPROVED