LRRC41 (leucine rich repeat containing 41) - Rat Genome Database

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Gene: LRRC41 (leucine rich repeat containing 41) Canis lupus familiaris
Analyze
Symbol: LRRC41
Name: leucine rich repeat containing 41
RGD ID: 12377479
Description: ENCODES a protein that exhibits identical protein binding (inferred); ASSOCIATED WITH Breast Cancer, Familial (ortholog); hereditary breast ovarian cancer syndrome (ortholog); non-Hodgkin lymphoma (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leucine-rich repeat-containing protein 41
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,092,739 - 14,111,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,092,767 - 14,111,040 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,215,822 - 14,234,089 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,245,627 - 14,264,146 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,245,587 - 14,264,146 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,046,917 - 14,065,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,115,420 - 14,133,893 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,184,885 - 14,203,383 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LRRC41
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,092,739 - 14,111,034 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,092,767 - 14,111,040 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,215,822 - 14,234,089 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,245,627 - 14,264,146 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,245,587 - 14,264,146 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,046,917 - 14,065,403 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,115,420 - 14,133,893 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,184,885 - 14,203,383 (+)NCBIUU_Cfam_GSD_1.0
LRRC41
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,277,462 - 46,303,616 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,261,196 - 46,303,616 (-)EnsemblGRCh38hg38GRCh38
GRCh37146,743,134 - 46,769,288 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,516,659 - 46,541,625 (-)NCBINCBI36Build 36hg18NCBI36
Celera145,031,452 - 45,056,418 (-)NCBICelera
Cytogenetic Map1p34.1-p33NCBI
HuRef144,859,915 - 44,884,883 (-)NCBIHuRef
CHM1_1146,861,090 - 46,886,063 (-)NCBICHM1_1
T2T-CHM13v2.0146,154,683 - 46,180,838 (-)NCBIT2T-CHM13v2.0
Lrrc41
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,932,466 - 115,954,306 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,932,466 - 115,954,240 (+)EnsemblGRCm39 Ensembl
GRCm384116,075,269 - 116,097,109 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,075,269 - 116,097,043 (+)EnsemblGRCm38mm10GRCm38
MGSCv374115,748,070 - 115,769,648 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,573,397 - 115,594,975 (+)NCBIMGSCv36mm8
Celera4114,813,605 - 114,835,193 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
Lrrc41
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,791,256 - 134,812,177 (+)NCBIGRCr8
mRatBN7.25129,554,547 - 129,575,450 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,554,547 - 129,575,449 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,170,571 - 132,191,534 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,925,455 - 133,946,418 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,947,590 - 133,968,559 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,927,609 - 134,948,530 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,927,609 - 134,948,529 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,711,342 - 138,732,261 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,234,186 - 136,255,107 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15136,239,412 - 136,260,333 (-)NCBI
Celera5128,084,534 - 128,105,232 (+)NCBICelera
Cytogenetic Map5q35NCBI
Lrrc41
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546411,976,259 - 11,996,588 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546411,976,259 - 11,996,588 (+)NCBIChiLan1.0ChiLan1.0
LRRC41
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,504,556 - 180,529,822 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,646,140 - 179,671,420 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,581,638 - 45,606,649 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,936,187 - 46,961,523 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,936,651 - 46,961,242 (-)Ensemblpanpan1.1panPan2
Lrrc41
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,491,569 - 61,514,578 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647427,315,488 - 27,339,288 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647427,316,351 - 27,338,895 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRC41
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6165,134,690 - 165,156,911 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16165,134,682 - 165,156,915 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,614,027 - 152,636,352 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LRRC41
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,485,038 - 86,510,688 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2086,485,106 - 86,512,989 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603330,476,452 - 30,502,278 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrc41
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249062,191,934 - 2,217,347 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249062,193,881 - 2,231,424 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LRRC41
146 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014119564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014119565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022427982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_845204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000006845   ⟹   ENSCAFP00000006338
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,092,767 - 14,111,040 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000073961   ⟹   ENSCAFP00000057296
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,095,137 - 14,111,040 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000089138   ⟹   ENSCAFP00000045509
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,092,767 - 14,111,040 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000090511   ⟹   ENSCAFP00000063313
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,092,767 - 14,111,040 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845035150   ⟹   ENSCAFP00845027513
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1514,245,587 - 14,264,143 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845035268   ⟹   ENSCAFP00845027610
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1514,248,024 - 14,264,146 (+)Ensembl
RefSeq Acc Id: XM_014119564   ⟹   XP_013975039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11514,094,740 - 14,111,034 (+)NCBI
Dog10K_Boxer_Tasha1514,217,962 - 14,234,089 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038495792   ⟹   XP_038351720
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,046,917 - 14,065,403 (+)NCBI
RefSeq Acc Id: XM_038495793   ⟹   XP_038351721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,049,057 - 14,065,403 (+)NCBI
RefSeq Acc Id: XM_038558166   ⟹   XP_038414094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,184,885 - 14,203,383 (+)NCBI
RefSeq Acc Id: XM_038558167   ⟹   XP_038414095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,187,025 - 14,203,383 (+)NCBI
RefSeq Acc Id: XM_038622039   ⟹   XP_038477967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,115,420 - 14,133,893 (+)NCBI
RefSeq Acc Id: XM_038622040   ⟹   XP_038477968
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,117,560 - 14,133,893 (+)NCBI
RefSeq Acc Id: XM_038687788   ⟹   XP_038543716
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,245,627 - 14,264,146 (+)NCBI
RefSeq Acc Id: XM_038687789   ⟹   XP_038543717
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,247,767 - 14,264,146 (+)NCBI
RefSeq Acc Id: XM_845204   ⟹   XP_850297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11514,092,740 - 14,111,034 (+)NCBI
Dog10K_Boxer_Tasha1514,215,822 - 14,234,089 (+)NCBI
Sequence:
RefSeq Acc Id: XP_850297   ⟸   XM_845204
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KRC6 (UniProtKB/TrEMBL),   A0A8C0NVM6 (UniProtKB/TrEMBL),   A0A8I3P055 (UniProtKB/TrEMBL),   A0A8C0KQE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013975039   ⟸   XM_014119564
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SSE2 (UniProtKB/TrEMBL),   A0A8I3PAX6 (UniProtKB/TrEMBL),   A0A8C0KQE6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000057296   ⟸   ENSCAFT00000073961
Ensembl Acc Id: ENSCAFP00000006338   ⟸   ENSCAFT00000006845
Ensembl Acc Id: ENSCAFP00000045509   ⟸   ENSCAFT00000089138
Ensembl Acc Id: ENSCAFP00000063313   ⟸   ENSCAFT00000090511
RefSeq Acc Id: XP_038351720   ⟸   XM_038495792
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351721   ⟸   XM_038495793
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477967   ⟸   XM_038622039
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038477968   ⟸   XM_038622040
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038543716   ⟸   XM_038687788
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KRC6 (UniProtKB/TrEMBL),   A0A8C0NVM6 (UniProtKB/TrEMBL),   A0A8I3P055 (UniProtKB/TrEMBL),   A0A8C0KQE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543717   ⟸   XM_038687789
- Peptide Label: isoform X2
- UniProtKB: A0A8C0SSE2 (UniProtKB/TrEMBL),   A0A8I3PAX6 (UniProtKB/TrEMBL),   A0A8C0KQE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414094   ⟸   XM_038558166
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KQE6 (UniProtKB/TrEMBL),   A0A8C0KRC6 (UniProtKB/TrEMBL),   A0A8C0NVM6 (UniProtKB/TrEMBL),   A0A8I3P055 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414095   ⟸   XM_038558167
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KQE6 (UniProtKB/TrEMBL),   A0A8C0SSE2 (UniProtKB/TrEMBL),   A0A8I3PAX6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845027610   ⟸   ENSCAFT00845035268
Ensembl Acc Id: ENSCAFP00845027513   ⟸   ENSCAFT00845035150

Promoters
RGD ID:13685901
Promoter ID:EPDNEW_C3968
Type:initiation region
Name:LRRC41_1
Description:leucine rich repeat containing 41
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11514,093,067 - 14,093,127EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004263 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019226 UniProtKB/TrEMBL
  ENSCAFG00040016288 UniProtKB/TrEMBL
  ENSCAFG00845019955 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006845.5 UniProtKB/TrEMBL
  ENSCAFT00000073961.2 UniProtKB/TrEMBL
  ENSCAFT00000090511.2 UniProtKB/TrEMBL
  ENSCAFT00030035378.1 UniProtKB/TrEMBL
  ENSCAFT00030035455.1 UniProtKB/TrEMBL
  ENSCAFT00040030014.1 UniProtKB/TrEMBL
  ENSCAFT00040030089.1 UniProtKB/TrEMBL
  ENSCAFT00845035150 ENTREZGENE
  ENSCAFT00845035150.1 UniProtKB/TrEMBL
  ENSCAFT00845035268 ENTREZGENE
  ENSCAFT00845035268.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu_rpt_41 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
KEGG Report cfa:608535 UniProtKB/TrEMBL
NCBI Gene LRRC41 ENTREZGENE
PANTHER LEUCINE-RICH REPEAT-CONTAINING PROTEIN 41 UniProtKB/TrEMBL
  PTHR15354 UniProtKB/TrEMBL
SMART LRR_RI UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
UniProt A0A8C0KQE6 ENTREZGENE
  A0A8C0KRC6 ENTREZGENE
  A0A8C0NVM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RNT9_CANLF UniProtKB/TrEMBL
  A0A8C0SSE2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P055 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PAX6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TEU9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:42798 ENTREZGENE