U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4) - Rat Genome Database

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Gene: U2AF1L4 (U2 small nuclear RNA auxiliary factor 1 like 4) Canis lupus familiaris
Analyze
Symbol: U2AF1L4
Name: U2 small nuclear RNA auxiliary factor 1 like 4
RGD ID: 12374821
Description: ENCODES a protein that exhibits metal ion binding (inferred); RNA binding (inferred); zinc ion binding (inferred); INVOLVED IN mRNA splicing, via spliceosome (inferred); ASSOCIATED WITH Brugada syndrome 5 (ortholog); dystonia (ortholog); hereditary spastic paraplegia 75 (ortholog); FOUND IN U2AF complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: splicing factor U2AF 26 kDa subunit; TMEM149; transmembrane protein 149
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,888,680 - 116,890,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,888,720 - 116,890,923 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,293,931 - 116,296,172 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,491,646 - 117,493,887 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,491,675 - 117,497,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,055,022 - 117,057,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,678,643 - 116,680,884 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,734,028 - 117,736,264 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
U2AF1L4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11116,888,680 - 116,890,911 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1116,888,720 - 116,890,923 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1116,293,931 - 116,296,172 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01117,491,646 - 117,493,887 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1117,491,675 - 117,497,074 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,055,022 - 117,057,262 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01116,678,643 - 116,680,884 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01117,734,028 - 117,736,264 (+)NCBIUU_Cfam_GSD_1.0
U2AF1L4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381935,742,464 - 35,745,418 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1935,742,464 - 35,745,445 (-)EnsemblGRCh38hg38GRCh38
GRCh371936,233,365 - 36,236,319 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361940,925,268 - 40,928,176 (-)NCBINCBI36Build 36hg18NCBI36
Build 341940,925,272 - 40,928,146NCBI
Celera1932,946,905 - 32,949,813 (-)NCBICelera
Cytogenetic Map19q13.12NCBI
HuRef1932,738,416 - 32,741,324 (-)NCBIHuRef
CHM1_11936,234,748 - 36,237,646 (-)NCBICHM1_1
T2T-CHM13v2.01938,287,776 - 38,290,728 (-)NCBIT2T-CHM13v2.0
U2af1l4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39730,262,765 - 30,264,789 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl730,262,769 - 30,267,385 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl730,262,726 - 30,264,790 (+)EnsemblGRCm39 Ensembl
GRCm38730,563,340 - 30,565,364 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl730,563,344 - 30,567,960 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl730,563,301 - 30,565,365 (+)EnsemblGRCm38mm10GRCm38
MGSCv37731,348,359 - 31,350,383 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36730,272,100 - 30,274,124 (+)NCBIMGSCv36mm8
Celera725,155,101 - 25,157,125 (+)NCBICelera
Cytogenetic Map7B1NCBI
cM Map718.61NCBI
U2af1l4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8194,943,684 - 94,945,906 (+)NCBIGRCr8
mRatBN7.2185,816,268 - 85,818,462 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl185,815,101 - 85,818,462 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,233,050 - 91,235,194 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0199,699,215 - 99,701,359 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0192,991,331 - 92,993,475 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,017,414 - 89,019,651 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,017,479 - 89,019,937 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,172,229 - 90,174,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,608,372 - 85,610,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1185,686,482 - 85,688,530 (+)NCBI
Celera180,187,746 - 80,189,793 (+)NCBICelera
Cytogenetic Map1q21NCBI
U2AF1L4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22041,736,801 - 41,739,749 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11943,722,105 - 43,725,074 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01932,672,304 - 32,675,256 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11941,406,661 - 41,409,548 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1941,406,661 - 41,409,548 (-)Ensemblpanpan1.1panPan2
U2af1l4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934911,065,553 - 11,067,704 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936570578,178 - 580,133 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936570578,088 - 580,321 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
U2AF1L4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl645,168,927 - 45,172,305 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1645,167,556 - 45,172,382 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2640,625,562 - 40,627,833 (-)NCBISscrofa10.2Sscrofa10.2susScr3
U2AF1L4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1630,652,352 - 30,655,077 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660738,443,549 - 8,446,421 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in U2AF1L4
20 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005616693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468511 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468512 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000011030   ⟹   ENSCAFP00000010223
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1116,888,720 - 116,890,907 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000068056   ⟹   ENSCAFP00000053045
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1116,888,720 - 116,890,907 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000088080   ⟹   ENSCAFP00000047784
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1116,888,720 - 116,890,908 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000090943   ⟹   ENSCAFP00000062052
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1116,888,720 - 116,890,923 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845002502   ⟹   ENSCAFP00845001989
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1117,491,675 - 117,497,074 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845002521   ⟹   ENSCAFP00845002003
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1117,491,675 - 117,493,594 (+)Ensembl
RefSeq Acc Id: XM_005616693   ⟹   XP_005616750
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11116,888,680 - 116,890,911 (+)NCBI
Dog10K_Boxer_Tasha1116,293,931 - 116,296,172 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038453018   ⟹   XP_038308946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1116,293,931 - 116,296,172 (+)NCBI
RefSeq Acc Id: XM_038453021   ⟹   XP_038308949
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1116,293,931 - 116,296,172 (+)NCBI
RefSeq Acc Id: XM_038468511   ⟹   XP_038324439
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11117,055,022 - 117,057,262 (+)NCBI
RefSeq Acc Id: XM_038468512   ⟹   XP_038324440
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11117,055,022 - 117,057,262 (+)NCBI
RefSeq Acc Id: XM_038468513   ⟹   XP_038324441
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11117,055,022 - 117,057,262 (+)NCBI
RefSeq Acc Id: XM_038529284   ⟹   XP_038385212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01117,734,028 - 117,736,264 (+)NCBI
RefSeq Acc Id: XM_038529285   ⟹   XP_038385213
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01117,734,028 - 117,736,264 (+)NCBI
RefSeq Acc Id: XM_038529286   ⟹   XP_038385214
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01117,734,028 - 117,736,264 (+)NCBI
RefSeq Acc Id: XM_038593541   ⟹   XP_038449469
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01116,678,643 - 116,680,884 (+)NCBI
RefSeq Acc Id: XM_038593542   ⟹   XP_038449470
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01116,678,643 - 116,680,884 (+)NCBI
RefSeq Acc Id: XM_038593543   ⟹   XP_038449471
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01116,678,643 - 116,680,884 (+)NCBI
RefSeq Acc Id: XM_038657395   ⟹   XP_038513323
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01117,491,646 - 117,493,887 (+)NCBI
RefSeq Acc Id: XM_038657396   ⟹   XP_038513324
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01117,491,646 - 117,493,887 (+)NCBI
RefSeq Acc Id: XM_038657397   ⟹   XP_038513325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01117,491,646 - 117,493,887 (+)NCBI
RefSeq Acc Id: XP_005616750   ⟸   XM_005616693
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z3X2 (UniProtKB/TrEMBL),   A0A8C0L1E7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000047784   ⟸   ENSCAFT00000088080
Ensembl Acc Id: ENSCAFP00000010223   ⟸   ENSCAFT00000011030
Ensembl Acc Id: ENSCAFP00000053045   ⟸   ENSCAFT00000068056
Ensembl Acc Id: ENSCAFP00000062052   ⟸   ENSCAFT00000090943
RefSeq Acc Id: XP_038324439   ⟸   XM_038468511
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038324440   ⟸   XM_038468512
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038324441   ⟸   XM_038468513
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038449469   ⟸   XM_038593541
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038449470   ⟸   XM_038593542
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038449471   ⟸   XM_038593543
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038513323   ⟸   XM_038657395
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z3X2 (UniProtKB/TrEMBL),   A0A8C0L1E7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038513324   ⟸   XM_038657396
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038513325   ⟸   XM_038657397
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L1S6 (UniProtKB/TrEMBL),   A0A8C0TDU3 (UniProtKB/TrEMBL),   A0A8I3MYY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308946   ⟸   XM_038453018
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038308949   ⟸   XM_038453021
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L1S6 (UniProtKB/TrEMBL),   A0A8C0TDU3 (UniProtKB/TrEMBL),   A0A8I3MYY4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385212   ⟸   XM_038529284
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L1E7 (UniProtKB/TrEMBL),   A0A8C0Z3X2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385213   ⟸   XM_038529285
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038385214   ⟸   XM_038529286
- Peptide Label: isoform X3
- UniProtKB: A0A8C0L1S6 (UniProtKB/TrEMBL),   A0A8C0TDU3 (UniProtKB/TrEMBL),   A0A8I3MYY4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845002003   ⟸   ENSCAFT00845002521
Ensembl Acc Id: ENSCAFP00845001989   ⟸   ENSCAFT00845002502
Protein Domains
C3H1-type   RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006856 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030006303 UniProtKB/TrEMBL
  ENSCAFG00040021644 UniProtKB/TrEMBL
  ENSCAFG00845001465 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000088080.2 UniProtKB/TrEMBL
  ENSCAFT00000100018.1 UniProtKB/TrEMBL
  ENSCAFT00030011587.1 UniProtKB/TrEMBL
  ENSCAFT00030011625.1 UniProtKB/TrEMBL
  ENSCAFT00040040179.1 UniProtKB/TrEMBL
  ENSCAFT00040040207.1 UniProtKB/TrEMBL
  ENSCAFT00845002502 ENTREZGENE
  ENSCAFT00845002502.1 UniProtKB/TrEMBL
  ENSCAFT00845002521.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  RRM_dom_euk UniProtKB/TrEMBL
  U2AF_small UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/TrEMBL
KEGG Report cfa:476480 UniProtKB/TrEMBL
NCBI Gene U2AF1L4 ENTREZGENE
PANTHER PTHR12620 UniProtKB/TrEMBL
  SPLICING FACTOR U2AF 26 KDA SUBUNIT UniProtKB/TrEMBL
  U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
  zf-CCCH UniProtKB/TrEMBL
PRINTS U2AUXFACTOR UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
  ZF_C3H1 UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
  ZnF_C3H1 UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8C0L1E7 ENTREZGENE
  A0A8C0L1S6 ENTREZGENE
  A0A8C0TDU3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z3X2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MJJ3_CANLF UniProtKB/TrEMBL
  A0A8I3MYY4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T0Q3_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:58341 ENTREZGENE