SRA1 (steroid receptor RNA activator 1) - Rat Genome Database

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Gene: SRA1 (steroid receptor RNA activator 1) Canis lupus familiaris
Analyze
Symbol: SRA1 (Ensembl: APBB3)
Name: steroid receptor RNA activator 1
RGD ID: 12373484
Description: ENCODES a protein that exhibits nuclear receptor binding (ortholog); obsolete nuclear receptor coactivator activity (ortholog); steroid receptor RNA activator RNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN estrogen signaling pathway; ASSOCIATED WITH autosomal dominant intellectual developmental disorder 31 (ortholog); congestive heart failure (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN ribonucleoprotein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,745,518 - 35,752,497 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,745,877 - 35,752,502 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,783,751 - 32,790,730 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,200,151 - 36,207,129 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,200,510 - 36,207,134 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,253,022 - 33,260,000 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,120,557 - 34,127,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,873,253 - 34,880,232 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SRA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,745,518 - 35,752,497 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,745,877 - 35,752,502 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,783,751 - 32,790,730 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,200,151 - 36,207,129 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,200,510 - 36,207,134 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,253,022 - 33,260,000 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,120,557 - 34,127,539 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,873,253 - 34,880,232 (-)NCBIUU_Cfam_GSD_1.0
SRA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,550,067 - 140,558,093 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,537,340 - 140,557,677 (-)EnsemblGRCh38hg38GRCh38
GRCh375139,929,652 - 139,937,678 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,909,837 - 139,917,862 (-)NCBINCBI36Build 36hg18NCBI36
Build 345139,910,273 - 139,917,220NCBI
Celera5136,006,404 - 136,014,428 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5135,074,991 - 135,083,015 (-)NCBIHuRef
CHM1_15139,362,900 - 139,370,926 (-)NCBICHM1_1
T2T-CHM13v2.05141,075,497 - 141,083,524 (-)NCBIT2T-CHM13v2.0
Sra1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,800,240 - 36,803,364 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,799,734 - 36,803,868 (-)EnsemblGRCm39 Ensembl
GRCm381836,667,187 - 36,670,311 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,666,681 - 36,670,815 (-)EnsemblGRCm38mm10GRCm38
MGSCv371836,826,841 - 36,829,965 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,793,221 - 36,796,269 (-)NCBIMGSCv36mm8
Celera1837,116,277 - 37,119,407 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Sra1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,543,347 - 28,547,474 (-)NCBIGRCr8
mRatBN7.21828,269,192 - 28,273,023 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,269,311 - 28,272,538 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,396,455 - 28,399,683 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,158,546 - 29,161,774 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,493,784 - 28,497,012 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,494,004 - 29,497,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,494,014 - 29,497,410 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,199,078 - 29,202,306 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,306,555 - 29,309,783 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,333,370 - 29,336,429 (-)NCBI
Celera1827,996,484 - 27,999,712 (-)NCBICelera
Cytogenetic Map18p11NCBI
Sra1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955418126,726 - 133,316 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955418126,111 - 133,498 (+)NCBIChiLan1.0ChiLan1.0
SRA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,808,039 - 135,815,645 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,947,590 - 133,955,302 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,914,506 - 135,922,704 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15142,032,113 - 142,040,137 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,032,119 - 142,039,188 (-)Ensemblpanpan1.1panPan2
Sra1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,086,253 - 152,092,622 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,519,087 - 9,525,123 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,518,719 - 9,525,195 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,307,012 - 142,313,738 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,307,009 - 142,314,613 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,250,853 - 148,257,575 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,194,462 - 43,203,134 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,194,693 - 43,202,057 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,681,266 - 34,689,988 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sra1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,315,236 - 33,321,795 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,314,878 - 33,322,297 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SRA1
49 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000009379   ⟹   ENSCAFP00000008706
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl235,745,877 - 35,752,502 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845003004   ⟹   ENSCAFP00845002396
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl236,200,510 - 36,207,134 (-)Ensembl
RefSeq Acc Id: XM_005617283   ⟹   XP_005617340
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,745,518 - 35,752,497 (-)NCBI
Dog10K_Boxer_Tasha232,783,751 - 32,790,730 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038469580   ⟹   XP_038325508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1233,253,022 - 33,260,000 (-)NCBI
RefSeq Acc Id: XM_038530346   ⟹   XP_038386274
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0234,873,253 - 34,880,232 (-)NCBI
RefSeq Acc Id: XM_038594596   ⟹   XP_038450524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0234,120,557 - 34,127,539 (-)NCBI
RefSeq Acc Id: XM_038658637   ⟹   XP_038514565
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0236,200,151 - 36,207,129 (-)NCBI
RefSeq Acc Id: XP_005617340   ⟸   XM_005617283
- UniProtKB: A0A8C0JL46 (UniProtKB/TrEMBL),   A0A8C0RX99 (UniProtKB/TrEMBL),   A0A8I3MEN5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000008706   ⟸   ENSCAFT00000009379
RefSeq Acc Id: XP_038325508   ⟸   XM_038469580
RefSeq Acc Id: XP_038450524   ⟸   XM_038594596
RefSeq Acc Id: XP_038514565   ⟸   XM_038658637
- UniProtKB: A0A8C0JL46 (UniProtKB/TrEMBL),   A0A8C0RX99 (UniProtKB/TrEMBL),   A0A8I3MEN5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038386274   ⟸   XM_038530346
- UniProtKB: A0A8C0JL46 (UniProtKB/TrEMBL),   A0A8C0RX99 (UniProtKB/TrEMBL),   A0A8I3MEN5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845002396   ⟸   ENSCAFT00845003004
Protein Domains
SRA1/Sec31

Promoters
RGD ID:13682444
Promoter ID:EPDNEW_C513
Type:multiple initiation site
Name:SRA1_1
Description:steroid receptor RNA activator 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1235,752,290 - 35,752,350EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005819 Ensembl
  ENSCAFG00030005275 UniProtKB/TrEMBL
  ENSCAFG00040003615 UniProtKB/TrEMBL
  ENSCAFG00845001716 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00030009701.1 UniProtKB/TrEMBL
  ENSCAFT00040006896.1 UniProtKB/TrEMBL
  ENSCAFT00845003004 ENTREZGENE
  ENSCAFT00845003004.1 UniProtKB/TrEMBL
Gene3D-CATH Functional domain of the splicing factor Prp18 UniProtKB/TrEMBL
InterPro SRA1/Sec31 UniProtKB/TrEMBL
  Steroid_recept_RNA_1 UniProtKB/TrEMBL
NCBI Gene SRA1 ENTREZGENE
PANTHER PTHR18834 UniProtKB/TrEMBL
  STEROID RECEPTOR RNA ACTIVATOR 1 UniProtKB/TrEMBL
Pfam SRA1 UniProtKB/TrEMBL
UniProt A0A8C0JL46 ENTREZGENE
  A0A8C0RX99 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MEN5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46788 ENTREZGENE