TMBIM1 (transmembrane BAX inhibitor motif containing 1) - Rat Genome Database

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Gene: TMBIM1 (transmembrane BAX inhibitor motif containing 1) Canis lupus familiaris
Analyze
Symbol: TMBIM1
Name: transmembrane BAX inhibitor motif containing 1
RGD ID: 12358465
Description: ENCODES a protein that exhibits death receptor binding (inferred); INVOLVED IN negative regulation of catalytic activity (ortholog); positive regulation of blood vessel remodeling (ortholog); ASSOCIATED WITH cerebrotendinous xanthomatosis (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN endoplasmic reticulum (inferred); endosome membrane (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,952,145 - 24,983,477 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,952,902 - 24,958,137 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3725,772,307 - 25,789,205 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03724,968,200 - 24,985,133 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,968,204 - 24,985,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,873,526 - 24,890,468 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,807,781 - 24,824,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,827,421 - 24,844,375 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
JBrowse:




References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TMBIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,952,145 - 24,983,477 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,952,902 - 24,958,137 (-)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3725,772,307 - 25,789,205 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03724,968,200 - 24,985,133 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3724,968,204 - 24,985,119 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13724,873,526 - 24,890,468 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03724,807,781 - 24,824,727 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03724,827,421 - 24,844,375 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
TMBIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,274,197 - 218,292,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,274,193 - 218,292,589 (-)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh372219,138,920 - 219,157,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,847,161 - 218,865,524 (-)NCBIBuild 36Build 36hg18NCBI36
Celera2212,905,492 - 212,923,864 (-)NCBICelera
Cytogenetic Map2q35ENTREZGENE
HuRef2210,992,006 - 211,010,384 (-)NCBIHuRef
CHM1_12219,145,398 - 219,163,764 (-)NCBICHM1_1
T2T-CHM13v2.02218,759,890 - 218,778,207 (-)NCBIT2T-CHM13v2.0
Tmbim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,327,406 - 74,343,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,327,406 - 74,349,137 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38174,288,247 - 74,304,336 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,288,247 - 74,305,622 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37174,334,821 - 74,350,910 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36174,221,461 - 74,237,367 (-)NCBIMGSCv36mm8
Celera174,849,600 - 74,865,677 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.53NCBI
Tmbim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,320,972 - 83,338,469 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl983,320,979 - 83,338,657 (-)EnsemblGRCr8
mRatBN7.2975,871,835 - 75,889,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,871,835 - 75,889,069 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx984,317,374 - 84,334,544 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,446,295 - 89,463,469 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,832,511 - 87,849,679 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd986,973,414 - 86,990,566 (-)NCBI
Lyon_Normotensive982,793,720 - 82,810,868 (-)NCBI
Lyon_Hypertensive982,933,718 - 82,950,898 (-)NCBI
F344_StmMcwi984,894,303 - 84,911,483 (-)NCBI
Rnor_6.0981,569,289 - 81,586,469 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,569,289 - 81,586,553 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0981,335,836 - 81,353,016 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4973,614,825 - 73,632,005 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera973,448,320 - 73,465,500 (-)NCBICelera
RGSC_v3.1973,761,807 - 73,770,449 (-)NCBI
Cytogenetic Map9q33NCBI
Tmbim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,092,522 - 15,099,021 (+)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_00495545315,083,179 - 15,100,197 (+)NCBIChiLan1.0ChiLan1.0
TMBIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213120,906,392 - 120,924,762 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B120,921,356 - 120,939,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,533,578 - 105,551,969 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,131,476 - 224,149,669 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,131,478 - 224,143,170 (-)EnsemblPanPan1.1 EnsemblpanPan2panpan1.1
Tmbim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap17180,341,894 - 180,358,817 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_024405303174,460,373 - 174,477,277 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569800,760 - 820,271 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936569803,154 - 820,000 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMBIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15120,348,735 - 120,365,007 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.115120,348,740 - 120,365,055 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMBIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap110105,743,702 - 105,762,037 (-)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_02366604095,227,649 - 95,245,993 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.110104,155,823 - 104,174,135 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,155,185 - 104,163,793 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Tmbim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248236,736,216 - 6,757,285 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_0046248236,735,497 - 6,756,093 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2528,224,542 - 28,238,220 (-)Ensembl
Tmbim1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v14147,740,758 - 147,757,584 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in TMBIM1
418 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000023243   ⟹   ENSCAFP00000021584
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3724,952,902 - 24,958,137 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845047412   ⟹   ENSCAFP00845037200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3724,968,204 - 24,981,275 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845047494   ⟹   ENSCAFP00845037264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3724,968,205 - 24,985,119 (-)Ensembl
RefSeq Acc Id: XM_038447928   ⟹   XP_038303856
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03724,968,200 - 24,985,133 (-)NCBI
RefSeq Acc Id: XM_038463732   ⟹   XP_038319660
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3725,772,307 - 25,789,205 (-)NCBI
RefSeq Acc Id: XM_038521926   ⟹   XP_038377854
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13724,873,526 - 24,890,468 (-)NCBI
RefSeq Acc Id: XM_038585720   ⟹   XP_038441648
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03724,827,421 - 24,844,375 (-)NCBI
RefSeq Acc Id: XM_038650101   ⟹   XP_038506029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03724,807,781 - 24,824,727 (-)NCBI
Ensembl Acc Id: ENSCAFP00000021584   ⟸   ENSCAFT00000023243
RefSeq Acc Id: XP_038377854   ⟸   XM_038521926
RefSeq Acc Id: XP_038506029   ⟸   XM_038650101
RefSeq Acc Id: XP_038303856   ⟸   XM_038447928
- UniProtKB: A0A8C0LP54 (UniProtKB/TrEMBL),   A0A8I3PXA4 (UniProtKB/TrEMBL),   A0A8I3QCH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319660   ⟸   XM_038463732
- UniProtKB: A0A8C0LP54 (UniProtKB/TrEMBL),   A0A8I3PXA4 (UniProtKB/TrEMBL),   A0A8I3QCH3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038441648   ⟸   XM_038585720
- UniProtKB: A0A8C0LP54 (UniProtKB/TrEMBL),   A0A8I3PXA4 (UniProtKB/TrEMBL),   A0A8I3QCH3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845037200   ⟸   ENSCAFT00845047412
Ensembl Acc Id: ENSCAFP00845037264   ⟸   ENSCAFT00845047494


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014636 Ensembl
  ENSCAFG00845026892 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845047412 ENTREZGENE
  ENSCAFT00845047412.1 UniProtKB/TrEMBL
  ENSCAFT00845047494.1 UniProtKB/TrEMBL
InterPro Bax_inhibitor_1-related UniProtKB/TrEMBL
KEGG Report cfa:102153649 UniProtKB/TrEMBL
NCBI Gene TMBIM1 ENTREZGENE
PANTHER PROTEIN LIFEGUARD 3 UniProtKB/TrEMBL
  PTHR23291 UniProtKB/TrEMBL
Pfam Bax1-I UniProtKB/TrEMBL
UniProt A0A8C0LP54 ENTREZGENE
  A0A8I3PXA4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QCH3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:49789 ENTREZGENE