PIRT (phosphoinositide interacting regulator of transient receptor potential channels) - Rat Genome Database

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Gene: PIRT (phosphoinositide interacting regulator of transient receptor potential channels) Canis lupus familiaris
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Symbol: PIRT
Name: phosphoinositide interacting regulator of transient receptor potential channels
RGD ID: 12352422
Description: ENCODES a protein that exhibits phosphatidylinositol bisphosphate binding (inferred); phosphatidylinositol-3,4,5-trisphosphate binding (inferred); transmembrane transporter binding (inferred); INVOLVED IN behavioral response to pain (ortholog); positive regulation of cation channel activity (ortholog); response to heat (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoinositide-interacting protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1535,085,480 - 35,095,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl535,086,173 - 35,086,589 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha535,221,420 - 35,231,628 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0535,190,218 - 35,200,470 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl535,189,884 - 35,200,152 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1535,155,599 - 35,165,838 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0535,112,111 - 35,122,361 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,294,218 - 35,304,417 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PIRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1535,085,480 - 35,095,752 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl535,086,173 - 35,086,589 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha535,221,420 - 35,231,628 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0535,190,218 - 35,200,470 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl535,189,884 - 35,200,152 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1535,155,599 - 35,165,838 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0535,112,111 - 35,122,361 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0535,294,218 - 35,304,417 (-)NCBIUU_Cfam_GSD_1.0
PIRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381710,822,470 - 10,838,087 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1710,822,470 - 10,838,087 (-)EnsemblGRCh38hg38GRCh38
GRCh371710,725,787 - 10,741,404 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361710,666,517 - 10,682,143 (-)NCBINCBI36Build 36hg18NCBI36
Celera1710,756,635 - 10,772,261 (-)NCBICelera
Cytogenetic Map17p12NCBI
HuRef1710,626,293 - 10,641,913 (-)NCBIHuRef
CHM1_11710,735,671 - 10,751,286 (-)NCBICHM1_1
T2T-CHM13v2.01710,730,377 - 10,745,996 (-)NCBIT2T-CHM13v2.0
Pirt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391166,802,731 - 66,820,703 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1166,802,807 - 66,820,702 (+)EnsemblGRCm39 Ensembl
GRCm381166,911,905 - 66,929,877 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1166,911,981 - 66,929,876 (+)EnsemblGRCm38mm10GRCm38
MGSCv371166,725,493 - 66,742,202 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361166,728,186 - 66,744,895 (+)NCBIMGSCv36mm8
Celera1173,851,239 - 73,867,838 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1140.59NCBI
Pirt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81052,112,235 - 52,127,140 (+)NCBIGRCr8
mRatBN7.21051,613,202 - 51,628,108 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1051,613,126 - 51,632,264 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1056,269,300 - 56,284,142 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01055,759,278 - 55,774,118 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01051,262,121 - 51,276,997 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01053,466,870 - 53,485,096 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1053,466,870 - 53,481,770 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01053,218,153 - 53,236,283 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41053,617,910 - 53,633,542 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1050,795,900 - 50,810,922 (+)NCBICelera
Cytogenetic Map10q24NCBI
Pirt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554676,375,992 - 6,391,764 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554676,375,992 - 6,391,770 (+)NCBIChiLan1.0ChiLan1.0
PIRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21962,912,650 - 62,928,354 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11767,722,060 - 67,737,858 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01740,815,724 - 40,831,539 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11745,563,171 - 45,578,827 (+)NCBIpanpan1.1PanPan1.1panPan2
Pirt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560250,185,168 - 50,203,870 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365953,662,647 - 3,663,054 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365953,659,356 - 3,677,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1255,513,315 - 55,519,578 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11255,513,291 - 55,526,290 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PIRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11610,164,563 - 10,175,835 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1610,167,342 - 10,167,755 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605911,165,747 - 11,177,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pirt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478613,191,776 - 13,204,810 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478613,189,723 - 13,204,891 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PIRT
169 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 16 9 5 6 26 21 12 14 9

Sequence


Ensembl Acc Id: ENSCAFT00000027891   ⟹   ENSCAFP00000025938
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl535,086,173 - 35,086,589 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845005188   ⟹   ENSCAFP00845004121
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl535,189,884 - 35,200,152 (-)Ensembl
RefSeq Acc Id: XM_005620055   ⟹   XP_005620112
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1535,085,480 - 35,095,752 (-)NCBI
Dog10K_Boxer_Tasha535,221,420 - 35,231,628 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038475705   ⟹   XP_038331633
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1535,155,599 - 35,165,838 (-)NCBI
RefSeq Acc Id: XM_038536890   ⟹   XP_038392818
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0535,294,218 - 35,304,417 (-)NCBI
RefSeq Acc Id: XM_038601039   ⟹   XP_038456967
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0535,112,111 - 35,122,361 (-)NCBI
RefSeq Acc Id: XM_038665608   ⟹   XP_038521536
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0535,190,218 - 35,200,470 (-)NCBI
RefSeq Acc Id: XP_005620112   ⟸   XM_005620055
- UniProtKB: A0A8C0T5P0 (UniProtKB/TrEMBL),   A0A8I3MIE2 (UniProtKB/TrEMBL),   A0A8C0JJ56 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000025938   ⟸   ENSCAFT00000027891
RefSeq Acc Id: XP_038331633   ⟸   XM_038475705
RefSeq Acc Id: XP_038456967   ⟸   XM_038601039
RefSeq Acc Id: XP_038521536   ⟸   XM_038665608
- UniProtKB: A0A8C0T5P0 (UniProtKB/TrEMBL),   A0A8I3MIE2 (UniProtKB/TrEMBL),   A0A8C0JJ56 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392818   ⟸   XM_038536890
- UniProtKB: A0A8C0JJ56 (UniProtKB/TrEMBL),   A0A8C0T5P0 (UniProtKB/TrEMBL),   A0A8I3MIE2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845004121   ⟸   ENSCAFT00845005188


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000017597 Ensembl
  ENSCAFG00000056927 UniProtKB/TrEMBL
  ENSCAFG00030002205 UniProtKB/TrEMBL
  ENSCAFG00040018575 UniProtKB/TrEMBL
  ENSCAFG00845002937 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000106855.1 UniProtKB/TrEMBL
  ENSCAFT00030004035.1 UniProtKB/TrEMBL
  ENSCAFT00040034302.1 UniProtKB/TrEMBL
  ENSCAFT00845005188 ENTREZGENE
  ENSCAFT00845005188.1 UniProtKB/TrEMBL
InterPro PIRT UniProtKB/TrEMBL
KEGG Report cfa:100686498 UniProtKB/TrEMBL
NCBI Gene PIRT ENTREZGENE
PANTHER PHOSPHOINOSITIDE-INTERACTING PROTEIN UniProtKB/TrEMBL
  PHOSPHOINOSITIDE-INTERACTING PROTEIN FAMILY MEMBER UniProtKB/TrEMBL
Pfam PIRT UniProtKB/TrEMBL
UniProt A0A8C0JJ56 ENTREZGENE
  A0A8C0T5P0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MIE2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44580 ENTREZGENE