SRL (sarcalumenin) - Rat Genome Database

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Gene: SRL (sarcalumenin) Canis lupus familiaris
Analyze
Symbol: SRL
Name: sarcalumenin
RGD ID: 12342275
Description: ENCODES a protein that exhibits GTP binding (inferred); INVOLVED IN response to muscle activity involved in regulation of muscle adaptation (ortholog); store-operated calcium entry (ortholog); ASSOCIATED WITH epilepsy (ortholog); idiopathic generalized epilepsy (ortholog); intellectual disability (ortholog); FOUND IN endomembrane system (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
NCBI Annotation Information: Annotation category: not annotated on reference assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1637,113,398 - 37,163,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl637,124,499 - 37,160,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,441,369 - 38,491,141 (+)NCBIDog10K_Boxer_Tasha
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
SRL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1637,113,398 - 37,163,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl637,124,499 - 37,160,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,441,369 - 38,491,141 (+)NCBIDog10K_Boxer_Tasha
SRL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,189,374 - 4,242,080 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,189,374 - 4,242,080 (-)EnsemblGRCh38hg38GRCh38
GRCh37164,239,375 - 4,292,081 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,179,376 - 4,232,082 (-)NCBINCBI36Build 36hg18NCBI36
Celera164,446,058 - 4,499,081 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,206,950 - 4,259,095 (-)NCBIHuRef
CHM1_1164,239,343 - 4,291,673 (-)NCBICHM1_1
T2T-CHM13v2.0164,216,710 - 4,269,414 (-)NCBIT2T-CHM13v2.0
Srl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,294,843 - 4,359,772 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,298,080 - 4,359,680 (-)EnsemblGRCm39 Ensembl
GRCm38164,476,979 - 4,541,908 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,480,216 - 4,541,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv37164,480,228 - 4,523,053 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,395,456 - 4,438,281 (-)NCBIMGSCv36mm8
Celera165,108,501 - 5,151,358 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.44NCBI
Srl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,540,365 - 11,584,506 (+)NCBIGRCr8
mRatBN7.21011,033,976 - 11,078,103 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1011,034,035 - 11,078,101 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,742,180 - 15,786,241 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01015,230,991 - 15,275,057 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,900,416 - 10,944,328 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01011,240,135 - 11,284,325 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1011,240,138 - 11,284,332 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01010,002,567 - 10,045,906 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41011,174,718 - 11,218,663 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11011,174,704 - 11,216,843 (+)NCBI
Celera109,994,332 - 10,038,413 (+)NCBICelera
Cytogenetic Map10q12NCBI
Srl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544213,200,440 - 13,238,227 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544213,200,237 - 13,242,816 (+)NCBIChiLan1.0ChiLan1.0
SRL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,710,312 - 4,780,107 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,494,762 - 8,564,430 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,107,619 - 3,161,180 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,280,767 - 4,332,786 (-)NCBIpanpan1.1PanPan1.1panPan2
Srl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,434,393 - 106,485,464 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936694224,023 - 275,069 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SRL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl338,073,562 - 38,111,932 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1338,073,379 - 38,111,936 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2339,240,792 - 39,264,478 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SRL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.153,861,921 - 3,928,865 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606826,764,018 - 26,830,961 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Srl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248241,981,609 - 2,021,159 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248241,979,539 - 2,041,085 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SRL
280 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000030520   ⟹   ENSCAFP00000028358
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl637,124,500 - 37,160,955 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000049429   ⟹   ENSCAFP00000039163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl637,124,499 - 37,160,955 (+)Ensembl
RefSeq Acc Id: XM_014114660   ⟹   XP_013970135
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1637,124,320 - 37,163,133 (+)NCBI
Dog10K_Boxer_Tasha638,452,305 - 38,491,141 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022420137   ⟹   XP_022275845
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1637,113,398 - 37,163,133 (+)NCBI
Dog10K_Boxer_Tasha638,441,369 - 38,491,141 (+)NCBI
Sequence:
RefSeq Acc Id: XM_547150   ⟹   XP_547150
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1637,124,308 - 37,163,133 (+)NCBI
Dog10K_Boxer_Tasha638,452,293 - 38,491,141 (+)NCBI
Sequence:
RefSeq Acc Id: XP_547150   ⟸   XM_547150
- Peptide Label: isoform X1
- UniProtKB: A0A8C0SNB7 (UniProtKB/TrEMBL),   A0A8P0NK40 (UniProtKB/TrEMBL),   A0A8C0LGH3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013970135   ⟸   XM_014114660
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RBZ6 (UniProtKB/TrEMBL),   A0A8P0PPB4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022275845   ⟸   XM_022420137
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSCAFP00000028358   ⟸   ENSCAFT00000030520
Ensembl Acc Id: ENSCAFP00000039163   ⟸   ENSCAFT00000049429
Protein Domains
Dynamin-type G


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019233 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030003640 UniProtKB/TrEMBL
  ENSCAFG00040015131 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000030520.5 UniProtKB/TrEMBL
  ENSCAFT00000102028.1 UniProtKB/TrEMBL
  ENSCAFT00030006817.1 UniProtKB/TrEMBL
  ENSCAFT00030006829.1 UniProtKB/TrEMBL
  ENSCAFT00040027883.1 UniProtKB/TrEMBL
  ENSCAFT00040027913.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.268.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro Dynamin_N UniProtKB/TrEMBL
  EHD_N UniProtKB/TrEMBL
  G_DYNAMIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  TRAFAC_Dynamin-like_GTPase UniProtKB/TrEMBL
KEGG Report cfa:490030 UniProtKB/TrEMBL
NCBI Gene SRL ENTREZGENE
PANTHER SARCALUMENIN UniProtKB/TrEMBL
  TRANSMEMBRANE GTPASE FZO UniProtKB/TrEMBL
Pfam Dynamin_N UniProtKB/TrEMBL
  EHD_N UniProtKB/TrEMBL
PROSITE G_DYNAMIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8C0LGH3 ENTREZGENE
  A0A8C0RBZ6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SNB7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NK40 ENTREZGENE
  A0A8P0PPB4 ENTREZGENE
UniProt Secondary A0A8P0NK40 UniProtKB/TrEMBL
  A0A8P0PPB4 UniProtKB/TrEMBL
VGNC ID VGNC:54070 ENTREZGENE