EIF4H (eukaryotic translation initiation factor 4H) - Rat Genome Database

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Gene: EIF4H (eukaryotic translation initiation factor 4H) Canis lupus familiaris
Analyze
Symbol: EIF4H
Name: eukaryotic translation initiation factor 4H
RGD ID: 12337470
Description: ENCODES a protein that exhibits RNA binding (inferred); translation initiation factor activity (inferred); INVOLVED IN developmental growth (ortholog); sexual reproduction (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); intestinal volvulus (ortholog); FOUND IN perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,180,189 - 6,202,835 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,181,827 - 6,207,116 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,878,270 - 7,905,406 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.065,994,613 - 6,021,884 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl65,994,619 - 6,021,897 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.165,985,558 - 6,012,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,933,300 - 5,960,439 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,096,813 - 6,123,967 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
EIF4H
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,180,189 - 6,202,835 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,181,827 - 6,207,116 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,878,270 - 7,905,406 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.065,994,613 - 6,021,884 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl65,994,619 - 6,021,897 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.165,985,558 - 6,012,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,933,300 - 5,960,439 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.066,096,813 - 6,123,967 (-)NCBIUU_Cfam_GSD_1.0
EIF4H
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,174,356 - 74,197,096 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl774,174,231 - 74,197,122 (+)EnsemblGRCh38hg38GRCh38
GRCh37773,588,686 - 73,611,426 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,226,642 - 73,249,365 (+)NCBINCBI36Build 36hg18NCBI36
Build 34773,033,356 - 73,056,080NCBI
Celera769,068,153 - 69,090,994 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef769,470,180 - 69,492,897 (+)NCBIHuRef
CHM1_1773,733,792 - 73,756,510 (+)NCBICHM1_1
T2T-CHM13v2.0775,376,368 - 75,399,096 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2772,921,778 - 72,944,501 (+)NCBI
Eif4h
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395134,648,726 - 134,668,263 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5134,648,575 - 134,668,344 (-)EnsemblGRCm39 Ensembl
GRCm385134,619,872 - 134,639,409 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,619,721 - 134,639,490 (-)EnsemblGRCm38mm10GRCm38
MGSCv375135,095,746 - 135,115,198 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365134,904,503 - 134,923,955 (-)NCBIMGSCv36mm8
Celera5131,627,926 - 131,647,368 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.71NCBI
Eif4h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,719,527 - 27,736,350 (+)NCBIGRCr8
mRatBN7.21222,083,155 - 22,099,876 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,082,835 - 22,099,876 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1223,226,405 - 23,243,089 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,837,491 - 23,854,172 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,903,979 - 22,920,627 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,093,119 - 25,109,805 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,093,149 - 25,109,799 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,093,323 - 27,110,202 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,148,332 - 23,164,980 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11223,008,888 - 23,025,536 (+)NCBI
Celera1223,847,161 - 23,863,817 (+)NCBICelera
Cytogenetic Map12q12NCBI
Eif4h
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545613,699,012 - 13,725,393 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545613,699,012 - 13,710,065 (-)NCBIChiLan1.0ChiLan1.0
EIF4H
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2690,700,764 - 90,725,147 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17138,965,396 - 138,989,418 (-)NCBINHGRI_mPanPan1
PanPan1.1781,339,091 - 81,348,585 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl781,336,947 - 81,348,585 (+)Ensemblpanpan1.1panPan2
EIF4H
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl311,320,797 - 11,348,473 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1311,321,486 - 11,348,473 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2311,003,785 - 11,031,697 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF4H
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,878,250 - 8,903,812 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl288,879,946 - 8,903,828 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660707,674,083 - 7,700,226 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif4h
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474013,779,024 - 13,801,809 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474013,779,387 - 13,801,679 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in EIF4H
236 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014114129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038477834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038477835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038536743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038536754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038539082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038539083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038603174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038667879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038667880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000019083   ⟹   ENSCAFP00000017689
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl66,182,036 - 6,190,364 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000068416   ⟹   ENSCAFP00000064906
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl66,181,827 - 6,207,116 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845004836   ⟹   ENSCAFP00845003868
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl65,994,619 - 6,021,897 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845004848   ⟹   ENSCAFP00845003879
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl65,994,620 - 6,021,807 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845004863   ⟹   ENSCAFP00845003891
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl65,995,481 - 6,021,801 (-)Ensembl
RefSeq Acc Id: XM_038477834   ⟹   XP_038333762
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.165,985,558 - 6,012,686 (-)NCBI
RefSeq Acc Id: XM_038477835   ⟹   XP_038333763
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.165,985,558 - 6,012,686 (-)NCBI
RefSeq Acc Id: XM_038536743   ⟹   XP_038392671
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha67,878,270 - 7,905,406 (-)NCBI
RefSeq Acc Id: XM_038536754   ⟹   XP_038392682
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha67,878,270 - 7,905,406 (-)NCBI
RefSeq Acc Id: XM_038539082   ⟹   XP_038395010
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.066,096,813 - 6,123,967 (-)NCBI
RefSeq Acc Id: XM_038539083   ⟹   XP_038395011
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.066,096,813 - 6,123,967 (-)NCBI
RefSeq Acc Id: XM_038603173   ⟹   XP_038459101
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.065,933,300 - 5,960,439 (-)NCBI
RefSeq Acc Id: XM_038603174   ⟹   XP_038459102
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.065,933,300 - 5,960,439 (-)NCBI
RefSeq Acc Id: XM_038667879   ⟹   XP_038523807
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.065,994,613 - 6,021,884 (-)NCBI
RefSeq Acc Id: XM_038667880   ⟹   XP_038523808
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.065,994,613 - 6,021,884 (-)NCBI
Ensembl Acc Id: ENSCAFP00000017689   ⟸   ENSCAFT00000019083
Ensembl Acc Id: ENSCAFP00000064906   ⟸   ENSCAFT00000068416
RefSeq Acc Id: XP_038333763   ⟸   XM_038477835
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038333762   ⟸   XM_038477834
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038459102   ⟸   XM_038603174
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038459101   ⟸   XM_038603173
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038523808   ⟸   XM_038667880
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KF46 (UniProtKB/TrEMBL),   A0A8C0NDC2 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038523807   ⟸   XM_038667879
- Peptide Label: isoform X1
- UniProtKB: A0A8C0N8I9 (UniProtKB/TrEMBL),   A0A8I3MHL6 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392682   ⟸   XM_038536754
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KF46 (UniProtKB/TrEMBL),   A0A8C0NDC2 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392671   ⟸   XM_038536743
- Peptide Label: isoform X1
- UniProtKB: A0A8C0N8I9 (UniProtKB/TrEMBL),   A0A8I3MHL6 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395011   ⟸   XM_038539083
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KF46 (UniProtKB/TrEMBL),   A0A8C0NDC2 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395010   ⟸   XM_038539082
- Peptide Label: isoform X1
- UniProtKB: A0A8C0N8I9 (UniProtKB/TrEMBL),   A0A8I3MHL6 (UniProtKB/TrEMBL),   A0A8I3MMC5 (UniProtKB/TrEMBL),   A0A8P0TRY8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845003868   ⟸   ENSCAFT00845004836
Ensembl Acc Id: ENSCAFP00845003891   ⟸   ENSCAFT00845004863
Ensembl Acc Id: ENSCAFP00845003879   ⟸   ENSCAFT00845004848
Protein Domains
RRM


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000012019 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013456 UniProtKB/TrEMBL
  ENSCAFG00040010117 UniProtKB/TrEMBL
  ENSCAFG00845002722 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000019083.5 UniProtKB/TrEMBL
  ENSCAFT00000103035.1 UniProtKB/TrEMBL
  ENSCAFT00030024979.1 UniProtKB/TrEMBL
  ENSCAFT00030025053.1 UniProtKB/TrEMBL
  ENSCAFT00030025106.1 UniProtKB/TrEMBL
  ENSCAFT00040018738.1 UniProtKB/TrEMBL
  ENSCAFT00040018788.1 UniProtKB/TrEMBL
  ENSCAFT00845004836 ENTREZGENE
  ENSCAFT00845004836.1 UniProtKB/TrEMBL
  ENSCAFT00845004848 ENTREZGENE
  ENSCAFT00845004848.1 UniProtKB/TrEMBL
  ENSCAFT00845004863.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro eIF4H_RRM UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
NCBI Gene EIF4H ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H UniProtKB/TrEMBL
  EUKARYOTIC TRANSLATION INITIATION FACTOR 4H UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8C0KF46 ENTREZGENE
  A0A8C0N8I9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NDC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RJF4_CANLF UniProtKB/TrEMBL
  A0A8I3MHL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHM6_CANLF UniProtKB/TrEMBL
  A0A8I3MMC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0TRY8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40291 ENTREZGENE