KLF17 (KLF transcription factor 17) - Rat Genome Database

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Gene: KLF17 (KLF transcription factor 17) Canis lupus familiaris
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Symbol: KLF17
Name: KLF transcription factor 17
RGD ID: 12327019
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN gamete generation (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Krueppel-like factor 17; Kruppel like factor 17
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,147,898 - 16,160,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,148,857 - 16,160,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1516,260,803 - 16,282,609 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01516,293,799 - 16,315,624 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,302,886 - 16,315,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,101,720 - 16,114,440 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,161,011 - 16,182,817 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,234,139 - 16,255,955 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
KLF17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11516,147,898 - 16,160,548 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1516,148,857 - 16,160,462 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1516,260,803 - 16,282,609 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01516,293,799 - 16,315,624 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1516,302,886 - 16,315,660 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11516,101,720 - 16,114,440 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01516,161,011 - 16,182,817 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01516,234,139 - 16,255,955 (-)NCBIUU_Cfam_GSD_1.0
KLF17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38144,043,927 - 44,135,140 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl144,118,821 - 44,135,140 (+)EnsemblGRCh38hg38GRCh38
GRCh37144,584,493 - 44,600,812 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36144,357,109 - 44,373,399 (+)NCBINCBI36Build 36hg18NCBI36
Build 34144,253,614 - 44,269,900NCBI
Celera142,868,030 - 42,884,304 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef142,699,331 - 42,715,631 (+)NCBIHuRef
CHM1_1144,700,581 - 44,716,865 (+)NCBICHM1_1
T2T-CHM13v2.0143,915,021 - 44,006,090 (+)NCBIT2T-CHM13v2.0
Klf17
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394117,613,856 - 117,622,863 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4117,615,033 - 117,622,845 (-)EnsemblGRCm39 Ensembl
GRCm384117,756,659 - 117,765,666 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4117,757,836 - 117,765,648 (-)EnsemblGRCm38mm10GRCm38
MGSCv374117,429,264 - 117,438,271 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364117,254,591 - 117,263,598 (-)NCBIMGSCv36mm8
Celera4112,741,336 - 112,742,651 (-)ENTREZGENECelera
Cytogenetic Map4D1NCBI
cM Map453.46NCBI
Klf17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85136,578,594 - 136,601,234 (-)NCBIGRCr8
mRatBN7.25131,293,068 - 131,315,878 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5131,307,476 - 131,315,084 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05136,602,472 - 136,610,058 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5136,602,395 - 136,610,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05140,375,706 - 140,399,709 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45138,234,501 - 138,241,255 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15138,239,726 - 138,246,481 (-)NCBI
Celera5129,856,540 - 129,864,126 (-)NCBICelera
Cytogenetic Map5q36NCBI
Klf17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555373,637,825 - 3,648,078 (+)NCBIChiLan1.0ChiLan1.0
KLF17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21182,673,849 - 182,691,665 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11181,815,268 - 181,833,054 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,419,910 - 43,435,499 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1144,721,612 - 44,807,348 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl144,791,190 - 44,802,965 (+)Ensemblpanpan1.1panPan2
Klf17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505859,589,209 - 59,598,337 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647425,413,907 - 25,422,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6167,176,834 - 167,188,418 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16167,176,834 - 167,188,418 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26154,739,301 - 154,775,750 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLF17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12088,651,224 - 88,666,423 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2088,654,702 - 88,665,822 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603328,252,756 - 28,267,778 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klf17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248923,374,538 - 3,383,943 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248923,374,594 - 3,383,928 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KLF17
126 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
2 1 4 2 1 1 1 1 1 4 2 2 8

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005629096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022428043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005310374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005310375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005370306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005370307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005404528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005404529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005438056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005438057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000007761   ⟹   ENSCAFP00000007193
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1516,148,857 - 16,160,462 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845048659   ⟹   ENSCAFP00845038171
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1516,302,886 - 16,315,660 (-)Ensembl
RefSeq Acc Id: XM_005629096   ⟹   XP_005629153
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11516,147,898 - 16,160,548 (-)NCBI
Dog10K_Boxer_Tasha1516,269,881 - 16,282,609 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038495940   ⟹   XP_038351868
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11516,101,720 - 16,114,440 (-)NCBI
RefSeq Acc Id: XM_038558315   ⟹   XP_038414243
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01516,243,218 - 16,255,955 (-)NCBI
RefSeq Acc Id: XM_038622204   ⟹   XP_038478132
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01516,170,093 - 16,182,817 (-)NCBI
RefSeq Acc Id: XM_038687933   ⟹   XP_038543861
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01516,302,888 - 16,315,624 (-)NCBI
RefSeq Acc Id: XR_005310374
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1516,269,880 - 16,282,609 (-)NCBI
RefSeq Acc Id: XR_005310375
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1516,260,803 - 16,282,609 (-)NCBI
RefSeq Acc Id: XR_005370306
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01516,243,217 - 16,255,955 (-)NCBI
RefSeq Acc Id: XR_005370307
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01516,234,139 - 16,255,955 (-)NCBI
RefSeq Acc Id: XR_005404528
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01516,170,092 - 16,182,817 (-)NCBI
RefSeq Acc Id: XR_005404529
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01516,161,011 - 16,182,817 (-)NCBI
RefSeq Acc Id: XR_005438056
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01516,302,887 - 16,315,624 (-)NCBI
RefSeq Acc Id: XR_005438057
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01516,293,799 - 16,315,624 (-)NCBI
RefSeq Acc Id: XP_005629153   ⟸   XM_005629096
- UniProtKB: A0A8I3PYA2 (UniProtKB/TrEMBL),   A0A8P0SAB6 (UniProtKB/TrEMBL),   A0A8C0RJQ0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000007193   ⟸   ENSCAFT00000007761
RefSeq Acc Id: XP_038351868   ⟸   XM_038495940
RefSeq Acc Id: XP_038478132   ⟸   XM_038622204
RefSeq Acc Id: XP_038543861   ⟸   XM_038687933
- UniProtKB: A0A8I3PYA2 (UniProtKB/TrEMBL),   A0A8P0SAB6 (UniProtKB/TrEMBL),   A0A8C0RJQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414243   ⟸   XM_038558315
- UniProtKB: A0A8C0Q9J1 (UniProtKB/TrEMBL),   A0A8C0RJQ0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845038171   ⟸   ENSCAFT00845048659
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004819 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013842 UniProtKB/TrEMBL
  ENSCAFG00040005134 UniProtKB/TrEMBL
  ENSCAFG00845027600 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000007761.5 UniProtKB/TrEMBL
  ENSCAFT00030025653.1 UniProtKB/TrEMBL
  ENSCAFT00040009619.1 UniProtKB/TrEMBL
  ENSCAFT00845048659 ENTREZGENE
  ENSCAFT00845048659.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene KLF17 ENTREZGENE
PANTHER KRUEPPEL-LIKE FACTOR 17 UniProtKB/TrEMBL
  KRUEPPEL-LIKE TRANSCRIPTION FACTOR UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0Q9J1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RJQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PYA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SAB6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42435 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-11 KLF17  KLF transcription factor 17  KLF17  Kruppel like factor 17  Symbol and/or name change 19259463 PROVISIONAL