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Gene: DKKL1 (dickkopf like acrosomal protein 1) Canis lupus familiaris

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Symbol:

DKKL1

Name:

dickkopf like acrosomal protein 1

RGD ID:

12316285

Description:

INVOLVED IN canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 12 (ortholog); FOUND IN acrosomal vesicle (inferred); extracellular region (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

dickkopf-like 1 (soggy); dickkopf-like protein 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,109,787 - 107,113,932 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,109,791 - 107,113,811 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,693,253 - 106,697,206 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,630,262 - 107,634,229 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,630,266 - 107,634,131 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,303,172 - 107,307,137 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,945,347 - 106,949,315 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,786,470 - 107,790,436 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 12 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

canonical Wnt signaling pathway (IEA,ISO)

negative regulation of canonical Wnt signaling pathway (IBA)

negative regulation of testosterone biosynthetic process (IEA)

penetration of zona pellucida (IEA)

positive regulation of apoptotic process (IEA)

positive regulation of fat cell differentiation (IEA,ISO)

Cellular Component

acrosomal vesicle (IEA)

extracellular region (IEA)

extracellular space (IBA)

Molecular Function

co-receptor binding (IBA)

protein binding (ISO)

receptor antagonist activity (IBA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

DKKL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	107,109,787 - 107,113,932 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	107,109,791 - 107,113,811 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	106,693,253 - 106,697,206 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	107,630,262 - 107,634,229 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	107,630,266 - 107,634,131 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	107,303,172 - 107,307,137 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	106,945,347 - 106,949,315 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	107,786,470 - 107,790,436 (-)	NCBI		UU_Cfam_GSD_1.0

DKKL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	49,360,515 - 49,375,116 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	49,361,783 - 49,375,116 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	49,867,134 - 49,878,373 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	54,558,854 - 54,570,185 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	54,558,853 - 54,570,183	NCBI
Celera	19	46,733,898 - 46,745,228 (+)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	46,243,555 - 46,254,943 (+)	NCBI		HuRef
CHM1_1	19	49,868,966 - 49,880,350 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	52,357,951 - 52,372,571 (+)	NCBI		T2T-CHM13v2.0

Dkkl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	44,856,949 - 44,861,592 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	44,856,943 - 44,861,571 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	45,207,525 - 45,212,165 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	45,207,519 - 45,212,147 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	52,462,895 - 52,467,253 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	45,075,567 - 45,079,892 (-)	NCBI		MGSCv36	mm8
Celera	7	40,663,416 - 40,667,775 (-)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	29.19	NCBI

Dkkl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	104,830,462 - 104,835,711 (-)	NCBI		GRCr8
mRatBN7.2	1	95,694,010 - 95,699,259 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	95,694,010 - 95,699,259 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	101,079,409 - 101,084,658 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	109,552,075 - 109,557,324 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	102,842,478 - 102,847,727 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	101,205,426 - 101,210,675 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	101,205,426 - 101,210,675 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	102,270,284 - 102,275,533 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	95,684,794 - 95,690,043 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	89,952,293 - 89,957,542 (-)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Dkkl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	1,445,149 - 1,449,004 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	1,445,082 - 1,449,167 (-)	NCBI	ChiLan1.0	ChiLan1.0

DKKL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	55,479,696 - 55,493,609 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	57,398,633 - 57,413,230 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	46,375,301 - 46,389,822 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	55,300,173 - 55,313,690 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	55,301,955 - 55,313,690 (+)	Ensembl	panpan1.1		panPan2

Dkkl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	21,638,880 - 21,645,597 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936664	3,257,698 - 3,264,565 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936664	3,257,744 - 3,263,787 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DKKL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	54,463,759 - 54,468,361 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	54,462,367 - 54,468,363 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

DKKL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	42,544,459 - 42,555,653 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	42,547,593 - 42,555,566 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	22,470,364 - 22,482,443 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dkkl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	4,816,277 - 4,819,740 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	4,816,383 - 4,820,082 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in DKKL1
42 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003638821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005616315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038467551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038467552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038467553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528257	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038528258	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038592554	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038592555	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038592556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038656343	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038656344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038656345	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_859219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000005919 ⟹ ENSCAFP00000005483

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	1	107,109,791 - 107,113,811 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845000156 ⟹ ENSCAFP00845000121

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	1	107,630,266 - 107,634,131 (-)	Ensembl

RefSeq Acc Id:

XM_003638821 ⟹ XP_003638869

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	107,109,787 - 107,113,927 (-)	NCBI
Dog10K_Boxer_Tasha	1	106,693,253 - 106,697,197 (-)	NCBI

Sequence:

show sequence

GCAGCTGATCCTACGCTCCAGGTATCCCGTCTGGGCTCGAGACCAGAACTGTTCAGATTTAACA
GTCTTTGGACGGCCCGCCAGAGTCTGAGAGTCCGGTGCCCGGGCTGTGGTCTAGCGTAAAGGCA
CGGCCCAGGAGAAGGGGCGGGGCGTGGGAGAAGGTGAAGAATGAGATCTGGCCTCCCGGCCCGC
CCCGCAATGTGGCAACCTCTGGTCCTGCTGCTGCTGCTCCCCTCTGCCCTGGTGCCCCCCTCCA
CTGCAGCCCCCATCCGCGATGCTGACGCCCAGGAGAGCTCCTCGGGTTTTCTAGGCCTCCAGAG
CCTAATCCAAGGCTTCACCCGGCTTTTCCTGAAAGATGACTTGCTGCGGGGCATGGACAGCTTC
TTCTCAGCCCCCATGGACTTCCGAGGCCTCCCCAGAAACTACCACCAAGAAGAGAACCAGGAGC
ACCGGCTGGGGAACAACACTCTCTCTAGCCACCTACAGATCGACAAGGTGACAGACAACAAAAC
AGGAGAGGTGCTGATCTCCAAGCAGGTGGTGGCATCCATTGAGCCGGGAGAGGGGAGTTTGGAG
GGTGACTGGAAGGTACCCAAGATAGAGGAGAAGGAAGCCCTGGTGCCTGTCCCGAAAGCCATCG
ACAGCTTCCACCCAGAACCCCATCCCCGAGTGGCCTTCTGGATAATGAAGCTGCCACGGCGGAG
GTCCCACCAGGACATTCAGGAGGGTGGCCGCTGGCTCAGCGAGAAGCGACACCGCCTGCAGGCC
ATCCGGGATGGGCTCCGGGAGGGGAGTCACGAGGACAGCCTTGAAGAGGGGACCCAGGGGTCCT
CCCACTCCAAGCTGCCAGCCCGCAAGACCCACTTCCTGTACATCCTCAGGCCCTCTCAGCAGCT
ATAGGGTGGGGGCTAGGGAACACCTGCATGTACCCCCCAGCCAGACCCCACCCCAAGCACCATA
TGGAAATAAAGTTCTTACATCTAGCA

hide sequence

RefSeq Acc Id:

XM_005616315 ⟹ XP_005616372

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	107,109,787 - 107,113,927 (-)	NCBI
Dog10K_Boxer_Tasha	1	106,693,253 - 106,697,206 (-)	NCBI

Sequence:

show sequence

GCAGCTGATCCTACGCTCCAGGTATCCCGTCTGGGCTCGAGACCAGAACTGTTCAGATTTAACA
GTCTTTGGACGGCCCGCCAGAGTCTGAGAGTCCGGTGCCCGGGCTGTGGTCTAGCGTAAAGGCA
CGGCCCAGGAGAAGGGGCGGGGCGTGGGAGAAGCCTCCCGGCCCGCCCCGCAATGTGGCAACCT
CTGGTCCTGCTGCTGCTGCTCCCCTCTGCCCTGGTGCCCCCCTCCACTGCAGCCCCCATCCGCG
ATGCTGACGCCCAGGAGAGCTCCTCGGGTTTTCTAGGCCTCCAGAGCCTAATCCAAGGCTTCAC
CCGGCTTTTCCTGAAAGATGACTTGCTGCGGGGCATGGACAGCTTCTTCTCAGCCCCCATGGAC
TTCCGAGGCCTCCCCAGAAACTACCACCAAGAAGAGAACCAGGAGCACCGGCTGGGGAACAACA
CTCTCTCTAGCCACCTACAGATCGACAAGGTGACAGACAACAAAACAGGAGAGGTGCTGATCTC
CAAGCAGGTGGTGGCATCCATTGAGCCGGGAGAGGGGAGTTTGGAGGGTGACTGGAAGGTACCC
AAGATAGAGGAGAAGGAAGCCCTGGTGCCTGTCCCGAAAGCCATCGACAGCTTCCACCCAGAAC
CCCATCCCCGAGTGGCCTTCTGGATAATGAAGCTGCCACGGCGGAGGTCCCACCAGGACATTCA
GGAGGGTGGCCGCTGGCTCAGCGAGAAGCGACACCGCCTGCAGGCCATCCGGGATGGGCTCCGG
GAGGGGAGTCACGAGGACAGCCTTGAAGAGGGGACCCAGGGGTCCTCCCACTCCAAGCTGCCAG
CCCGCAAGACCCACTTCCTGTACATCCTCAGGCCCTCTCAGCAGCTATAGGGTGGGGGCTAGGG
AACACCTGCATGTACCCCCCAGCCAGACCCCACCCCAAGCACCATATGGAAATAAAGTTCTTAC
ATCTAGCA

hide sequence

RefSeq Acc Id:

XM_038467551 ⟹ XP_038323479

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	107,303,172 - 107,307,128 (-)	NCBI

RefSeq Acc Id:

XM_038467552 ⟹ XP_038323480

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	107,303,172 - 107,307,137 (-)	NCBI

RefSeq Acc Id:

XM_038467553 ⟹ XP_038323481

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	1	107,303,172 - 107,307,128 (-)	NCBI

RefSeq Acc Id:

XM_038528256 ⟹ XP_038384184

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	107,786,470 - 107,790,427 (-)	NCBI

RefSeq Acc Id:

XM_038528257 ⟹ XP_038384185

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	107,786,470 - 107,790,436 (-)	NCBI

RefSeq Acc Id:

XM_038528258 ⟹ XP_038384186

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	1	107,786,470 - 107,790,427 (-)	NCBI

RefSeq Acc Id:

XM_038592554 ⟹ XP_038448482

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	1	106,945,347 - 106,949,306 (-)	NCBI

RefSeq Acc Id:

XM_038592555 ⟹ XP_038448483

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	1	106,945,347 - 106,949,315 (-)	NCBI

RefSeq Acc Id:

XM_038592556 ⟹ XP_038448484

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	1	106,945,347 - 106,949,306 (-)	NCBI

RefSeq Acc Id:

XM_038656343 ⟹ XP_038512271

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	107,630,262 - 107,634,220 (-)	NCBI

RefSeq Acc Id:

XM_038656344 ⟹ XP_038512272

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	107,630,262 - 107,634,229 (-)	NCBI

RefSeq Acc Id:

XM_038656345 ⟹ XP_038512273

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	1	107,630,262 - 107,634,220 (-)	NCBI

RefSeq Acc Id:

XM_859219 ⟹ XP_864312

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	1	107,109,787 - 107,113,932 (-)	NCBI
Dog10K_Boxer_Tasha	1	106,693,253 - 106,697,197 (-)	NCBI

Sequence:

show sequence

CTCGCGCAGCTGATCCTACGCTCCAGGTATCCCGTCTGGGCTCGAGACCAGAACTGTTCAGATT
TAACAGTCTTTGGACGGCCCGCCAGAGTCTGAGAGTCCGGTGCCCGGGCTGTGGTCTAGCGTAA
AGGCACGGCCCAGGAGAAGGGGCGGGGCGTGGGAGAAGGTGAAGAATGAGATCTGGCCTCCCGG
CCCGCCCCGCAATGTGGCAACCTCTGGTCCTGCTGCTGCTGCTCCCCTCTGCCCTGGTGCCCCC
CTCCACTGCAGCCCCCATCCGCGATGCTGACGCCCAGGAGAGCTCCTCGGGTTTTCTAGGCCTC
CAGAGCCTAATCCAAGGCTTCACCCGGCTTTTCCTGAAAGATGACTTGCTGCGGGGCATGGACA
GCTTCTTCTCAGCCCCCATGGACTTCCGAGGCCTCCCCAGAAACTACCACCAAGAAGAGAACCA
GGAGCACCGGCTGGGGAACAACACTCTCTCTAGCCACCTACAGATCGACAAGGTACCCAAGATA
GAGGAGAAGGAAGCCCTGGTGCCTGTCCCGAAAGCCATCGACAGCTTCCACCCAGAACCCCATC
CCCGAGTGGCCTTCTGGATAATGAAGCTGCCACGGCGGAGGTCCCACCAGGACATTCAGGAGGG
TGGCCGCTGGCTCAGCGAGAAGCGACACCGCCTGCAGGCCATCCGGGATGGGCTCCGGGAGGGG
AGTCACGAGGACAGCCTTGAAGAGGGGACCCAGGGGTCCTCCCACTCCAAGCTGCCAGCCCGCA
AGACCCACTTCCTGTACATCCTCAGGCCCTCTCAGCAGCTATAGGGTGGGGGCTAGGGAACACC
TGCATGTACCCCCCAGCCAGACCCCACCCCAAGCACCATATGGAAATAAAGTTCTTACATCTAG
CA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003638869	(Get FASTA)	NCBI Sequence Viewer
	XP_005616372	(Get FASTA)	NCBI Sequence Viewer
	XP_038323479	(Get FASTA)	NCBI Sequence Viewer
	XP_038323480	(Get FASTA)	NCBI Sequence Viewer
	XP_038323481	(Get FASTA)	NCBI Sequence Viewer
	XP_038384184	(Get FASTA)	NCBI Sequence Viewer
	XP_038384185	(Get FASTA)	NCBI Sequence Viewer
	XP_038384186	(Get FASTA)	NCBI Sequence Viewer
	XP_038448482	(Get FASTA)	NCBI Sequence Viewer
	XP_038448483	(Get FASTA)	NCBI Sequence Viewer
	XP_038448484	(Get FASTA)	NCBI Sequence Viewer
	XP_038512271	(Get FASTA)	NCBI Sequence Viewer
	XP_038512272	(Get FASTA)	NCBI Sequence Viewer
	XP_038512273	(Get FASTA)	NCBI Sequence Viewer
	XP_864312	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000005483.4
	ENSCAFP00030026905.1
	ENSCAFP00040029481.1
	ENSCAFP00845000121
	ENSCAFP00845000121.1

RefSeq Acc Id:	XP_005616372 ⟸ XM_005616315
- Peptide Label:	isoform X2
- UniProtKB:	E2QYS1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MWQPLVLLLLLPSALVPPSTAAPIRDADAQESSSGFLGLQSLIQGFTRLFLKDDLLRGMDSFFS APMDFRGLPRNYHQEENQEHRLGNNTLSSHLQIDKVTDNKTGEVLISKQVVASIEPGEGSLEGD WKVPKIEEKEALVPVPKAIDSFHPEPHPRVAFWIMKLPRRRSHQDIQEGGRWLSEKRHRLQAIR DGLREGSHEDSLEEGTQGSSHSKLPARKTHFLYILRPSQQL hide sequence

RefSeq Acc Id:

XP_864312 ⟸ XM_859219

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRSGLPARPAMWQPLVLLLLLPSALVPPSTAAPIRDADAQESSSGFLGLQSLIQGFTRLFLKDD
LLRGMDSFFSAPMDFRGLPRNYHQEENQEHRLGNNTLSSHLQIDKVPKIEEKEALVPVPKAIDS
FHPEPHPRVAFWIMKLPRRRSHQDIQEGGRWLSEKRHRLQAIRDGLREGSHEDSLEEGTQGSSH
SKLPARKTHFLYILRPSQQL

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RefSeq Acc Id:	XP_003638869 ⟸ XM_003638821
- Peptide Label:	isoform X1
- UniProtKB:	A0A8P0N6I0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRSGLPARPAMWQPLVLLLLLPSALVPPSTAAPIRDADAQESSSGFLGLQSLIQGFTRLFLKDD LLRGMDSFFSAPMDFRGLPRNYHQEENQEHRLGNNTLSSHLQIDKVTDNKTGEVLISKQVVASI EPGEGSLEGDWKVPKIEEKEALVPVPKAIDSFHPEPHPRVAFWIMKLPRRRSHQDIQEGGRWLS EKRHRLQAIRDGLREGSHEDSLEEGTQGSSHSKLPARKTHFLYILRPSQQL hide sequence

Ensembl Acc Id:

ENSCAFP00000005483 ⟸ ENSCAFT00000005919

RefSeq Acc Id:	XP_038323480 ⟸ XM_038467552
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038323481 ⟸ XM_038467553
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038323479 ⟸ XM_038467551
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038448483 ⟸ XM_038592555
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038448484 ⟸ XM_038592556
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038448482 ⟸ XM_038592554
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038512272 ⟸ XM_038656344
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LN60 (UniProtKB/TrEMBL), A0A8C0NHJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038512273 ⟸ XM_038656345
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038512271 ⟸ XM_038656343
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0Z1E6 (UniProtKB/TrEMBL), A0A8I3M9V3 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384185 ⟸ XM_038528257
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LN60 (UniProtKB/TrEMBL), A0A8C0NHJ1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038384186 ⟸ XM_038528258
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038384184 ⟸ XM_038528256
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0Z1E6 (UniProtKB/TrEMBL), A0A8I3M9V3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845000121 ⟸ ENSCAFT00845000156

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000003681	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030016683	UniProtKB/TrEMBL
	ENSCAFG00040018336	UniProtKB/TrEMBL
	ENSCAFG00845000090	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000005919.5	UniProtKB/TrEMBL
	ENSCAFT00030030843.1	UniProtKB/TrEMBL
	ENSCAFT00040033881.1	UniProtKB/TrEMBL
	ENSCAFT00845000156	ENTREZGENE
	ENSCAFT00845000156.1	UniProtKB/TrEMBL
InterPro	DKK1-4	UniProtKB/TrEMBL
	DKKL1	UniProtKB/TrEMBL
KEGG Report	cfa:610302	UniProtKB/TrEMBL
NCBI Gene	DKKL1	ENTREZGENE
PANTHER	DICKKOPF-LIKE PROTEIN 1	UniProtKB/TrEMBL
	DICKKOPF3-LIKE 3	UniProtKB/TrEMBL
UniProt	A0A8C0LN60	ENTREZGENE
	A0A8C0NHJ1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z1E6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3M9V3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0N6I0	ENTREZGENE, UniProtKB/TrEMBL
	E2QYS1	ENTREZGENE
VGNC ID	VGNC:39973	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar