UBE2E3 (ubiquitin conjugating enzyme E2 E3) - Rat Genome Database

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Gene: UBE2E3 (ubiquitin conjugating enzyme E2 E3) Canis lupus familiaris
Analyze
Symbol: UBE2E3
Name: ubiquitin conjugating enzyme E2 E3
RGD ID: 12309064
Description: ENCODES a protein that exhibits ATP binding (inferred); transferase activity (inferred); ubiquitin conjugating enzyme activity (inferred); INVOLVED IN protein K11-linked ubiquitination (inferred); protein K48-linked ubiquitination (inferred); protein K63-linked ubiquitination (inferred); FOUND IN membrane (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin-conjugating enzyme E2 E3; ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13624,201,066 - 24,285,695 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3624,187,672 - 24,445,417 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3624,219,719 - 24,305,729 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03624,364,757 - 24,450,910 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3624,364,632 - 24,451,366 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13624,454,603 - 24,540,580 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03624,419,433 - 24,505,500 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03624,552,821 - 24,640,159 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
UBE2E3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13624,201,066 - 24,285,695 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3624,187,672 - 24,445,417 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3624,219,719 - 24,305,729 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03624,364,757 - 24,450,910 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3624,364,632 - 24,451,366 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13624,454,603 - 24,540,580 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03624,419,433 - 24,505,500 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03624,552,821 - 24,640,159 (+)NCBIUU_Cfam_GSD_1.0
UBE2E3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382180,980,360 - 181,063,425 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2180,967,248 - 181,076,585 (+)EnsemblGRCh38hg38GRCh38
GRCh372181,845,087 - 181,928,152 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362181,553,357 - 181,636,395 (+)NCBINCBI36Build 36hg18NCBI36
Build 342181,670,617 - 181,753,656NCBI
Celera2175,442,077 - 175,524,385 (+)NCBICelera
Cytogenetic Map2q31.3NCBI
HuRef2173,700,355 - 173,784,501 (+)NCBIHuRef
CHM1_12181,851,167 - 181,933,941 (+)NCBICHM1_1
T2T-CHM13v2.02181,470,000 - 181,553,425 (+)NCBIT2T-CHM13v2.0
Ube2e3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39278,698,696 - 78,759,132 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl278,698,468 - 78,751,637 (+)EnsemblGRCm39 Ensembl
GRCm38278,868,236 - 78,928,786 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl278,868,124 - 78,921,293 (+)EnsemblGRCm38mm10GRCm38
MGSCv37278,709,204 - 78,760,740 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36278,669,886 - 78,721,422 (+)NCBIMGSCv36mm8
Celera280,527,758 - 80,577,866 (+)NCBICelera
Cytogenetic Map2C3NCBI
cM Map247.15NCBI
Ube2e3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8384,194,246 - 84,250,232 (+)NCBIGRCr8
mRatBN7.2363,786,976 - 63,851,400 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl363,786,650 - 63,843,237 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx367,139,337 - 67,195,213 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0375,722,938 - 75,778,812 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0373,478,822 - 73,534,729 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0365,815,076 - 65,876,256 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl365,815,080 - 65,871,363 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0372,378,562 - 72,439,742 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4361,554,632 - 61,610,921 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1361,451,007 - 61,507,149 (+)NCBI
Celera363,252,961 - 63,308,175 (+)NCBICelera
Cytogenetic Map3q24NCBI
Ube2e3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540316,151,629 - 16,239,855 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540316,151,629 - 16,239,855 (-)NCBIChiLan1.0ChiLan1.0
UBE2E3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21383,631,315 - 83,714,106 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B83,645,868 - 83,729,081 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B68,245,028 - 68,328,059 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B186,057,033 - 186,139,384 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B186,057,033 - 186,139,384 (+)Ensemblpanpan1.1panPan2
Ube2e3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303141,229,052 - 141,312,639 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365099,782,955 - 9,869,517 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365099,782,955 - 9,866,542 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2E3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1586,471,156 - 86,561,911 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11586,470,912 - 86,562,297 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21596,079,238 - 96,201,688 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2E3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11066,476,872 - 66,561,465 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1066,477,515 - 66,561,079 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040133,014,545 - 133,097,720 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube2e3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248442,788,920 - 2,889,339 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248442,789,838 - 2,886,403 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in UBE2E3
1036 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038447235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038447236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038463393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038521313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038585019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038649433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_845749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000022479   ⟹   ENSCAFP00000020872
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3624,187,672 - 24,285,367 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000059788   ⟹   ENSCAFP00000045663
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3624,187,672 - 24,285,676 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000069763   ⟹   ENSCAFP00000062134
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3624,200,500 - 24,445,417 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000075462   ⟹   ENSCAFP00000047258
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3624,200,500 - 24,284,006 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000077338   ⟹   ENSCAFP00000064748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3624,187,672 - 24,285,367 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845047547   ⟹   ENSCAFP00845037308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3624,364,632 - 24,451,366 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845047586   ⟹   ENSCAFP00845037341
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3624,364,632 - 24,451,366 (+)Ensembl
RefSeq Acc Id: XM_038447235   ⟹   XP_038303163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03624,364,757 - 24,450,910 (+)NCBI
RefSeq Acc Id: XM_038447236   ⟹   XP_038303164
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03624,365,695 - 24,450,910 (+)NCBI
RefSeq Acc Id: XM_038463392   ⟹   XP_038319320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3624,219,719 - 24,305,729 (+)NCBI
RefSeq Acc Id: XM_038463393   ⟹   XP_038319321
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha3624,220,632 - 24,305,729 (+)NCBI
RefSeq Acc Id: XM_038521312   ⟹   XP_038377240
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13624,454,603 - 24,540,580 (+)NCBI
RefSeq Acc Id: XM_038521313   ⟹   XP_038377241
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13624,455,523 - 24,540,580 (+)NCBI
RefSeq Acc Id: XM_038585017   ⟹   XP_038440945
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03624,552,821 - 24,640,159 (+)NCBI
RefSeq Acc Id: XM_038585018   ⟹   XP_038440946
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03624,554,128 - 24,640,159 (+)NCBI
RefSeq Acc Id: XM_038585019   ⟹   XP_038440947
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03624,555,067 - 24,640,159 (+)NCBI
RefSeq Acc Id: XM_038649432   ⟹   XP_038505360
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03624,419,433 - 24,505,500 (+)NCBI
RefSeq Acc Id: XM_038649433   ⟹   XP_038505361
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03624,420,357 - 24,505,500 (+)NCBI
Ensembl Acc Id: ENSCAFP00000045663   ⟸   ENSCAFT00000059788
Ensembl Acc Id: ENSCAFP00000062134   ⟸   ENSCAFT00000069763
Ensembl Acc Id: ENSCAFP00000064748   ⟸   ENSCAFT00000077338
Ensembl Acc Id: ENSCAFP00000047258   ⟸   ENSCAFT00000075462
Ensembl Acc Id: ENSCAFP00000020872   ⟸   ENSCAFT00000022479
RefSeq Acc Id: XP_038377240   ⟸   XM_038521312
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038377241   ⟸   XM_038521313
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505360   ⟸   XM_038649432
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038505361   ⟸   XM_038649433
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038303163   ⟸   XM_038447235
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038303164   ⟸   XM_038447236
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319320   ⟸   XM_038463392
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038319321   ⟸   XM_038463393
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440945   ⟸   XM_038585017
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038440946   ⟸   XM_038585018
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038440947   ⟸   XM_038585019
- Peptide Label: isoform X1
- UniProtKB: A0A8C0K0V2 (UniProtKB/TrEMBL),   A0A8I3PR80 (UniProtKB/TrEMBL),   A0A8P0SYU0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845037308   ⟸   ENSCAFT00845047547
Ensembl Acc Id: ENSCAFP00845037341   ⟸   ENSCAFT00845047586
Protein Domains
UBC core


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000014163 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007475 UniProtKB/TrEMBL
  ENSCAFG00040020216 UniProtKB/TrEMBL
  ENSCAFG00845026988 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000059788.2 UniProtKB/TrEMBL
  ENSCAFT00000077338.2 UniProtKB/TrEMBL
  ENSCAFT00030013775.1 UniProtKB/TrEMBL
  ENSCAFT00040037439.1 UniProtKB/TrEMBL
  ENSCAFT00845047547.1 UniProtKB/TrEMBL
  ENSCAFT00845047586 ENTREZGENE
  ENSCAFT00845047586.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/TrEMBL
NCBI Gene UBE2E3 ENTREZGENE
PANTHER UBIQUITIN-CONJUGATING ENZYME E2 UniProtKB/TrEMBL
  UBIQUITIN-CONJUGATING ENZYME E2 E3 UniProtKB/TrEMBL
Pfam UQ_con UniProtKB/TrEMBL
PROSITE UBC_1 UniProtKB/TrEMBL
  UBC_2 UniProtKB/TrEMBL
SMART UBCc UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/TrEMBL
UniProt A0A8C0K0V2 ENTREZGENE
  A0A8C0T703_CANLF UniProtKB/TrEMBL
  A0A8I3PR80 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PVW5_CANLF UniProtKB/TrEMBL
  A0A8P0SYU0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53110 ENTREZGENE