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Gene: UBE2E3 (ubiquitin conjugating enzyme E2 E3) Homo sapiens
Symbol: UBE2E3
Name: ubiquitin conjugating enzyme E2 E3
Description: Exhibits ubiquitin-protein transferase activity. Involved in protein K11-linked ubiquitination; protein K48-linked ubiquitination; and protein K63-linked ubiquitination. Predicted to localize to the cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E2 ubiquitin-conjugating enzyme E3; UBCH9; UbcM2; ubiquitin carrier protein E3; ubiquitin conjugating enzyme E2E 3; ubiquitin-conjugating enzyme E2 E3; ubiquitin-conjugating enzyme E2-23 kDa; ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast); ubiquitin-protein ligase E3
Mus musculus (house mouse) : Ube2e3 (ubiquitin-conjugating enzyme E2E 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ube2e3 (ubiquitin-conjugating enzyme E2E 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2e3 (ubiquitin conjugating enzyme E2 E3)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2E3 (ubiquitin conjugating enzyme E2 E3)
Canis lupus familiaris (dog) : UBE2E3 (ubiquitin conjugating enzyme E2 E3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2e3 (ubiquitin conjugating enzyme E2 E3)
Sus scrofa (pig) : UBE2E3 (ubiquitin conjugating enzyme E2 E3)
Chlorocebus sabaeus (green monkey) : UBE2E3 (ubiquitin conjugating enzyme E2 E3)
Heterocephalus glaber (naked mole-rat) : Ube2e3 (ubiquitin conjugating enzyme E2 E3)
more info ...
Related Pseudogenes: UBE2E4P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2180,967,248 - 181,076,585 (+)Ensembl
GRCh382180,980,385 - 181,063,427 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372181,845,112 - 181,928,154 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362181,553,357 - 181,636,395 (+)NCBINCBI36hg18NCBI36
Build 342181,670,617 - 181,753,656NCBI
Celera2175,442,077 - 175,524,385 (+)NCBI
Cytogenetic Map2q31.3NCBI
HuRef2173,700,355 - 173,784,501 (+)NCBIHuRef
CHM1_12181,851,167 - 181,933,941 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on UBE2E3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318925
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.