XPO7 (exportin 7) - Rat Genome Database

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Gene: XPO7 (exportin 7) Canis lupus familiaris
Analyze
Symbol: XPO7
Name: exportin 7
RGD ID: 12297270
Description: ENCODES a protein that exhibits nuclear export signal receptor activity (inferred); small GTPase binding (inferred); INVOLVED IN intracellular protein transport (inferred); nuclear export (inferred); nuclear transport (inferred); ASSOCIATED WITH atrial fibrillation (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); nuclear pore (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exportin-7
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,236,794 - 35,277,211 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,233,034 - 35,277,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,825,644 - 35,866,129 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,447,634 - 35,487,920 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,447,639 - 35,539,299 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,392,862 - 35,433,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,247,433 - 35,287,914 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,402,987 - 35,443,489 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nuclear pore  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
XPO7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,236,794 - 35,277,211 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,233,034 - 35,277,124 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,825,644 - 35,866,129 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,447,634 - 35,487,920 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,447,639 - 35,539,299 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,392,862 - 35,433,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,247,433 - 35,287,914 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,402,987 - 35,443,489 (-)NCBIUU_Cfam_GSD_1.0
XPO7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38821,919,662 - 22,006,585 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl821,919,662 - 22,006,585 (+)EnsemblGRCh38hg38GRCh38
GRCh37821,777,173 - 21,864,096 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36821,833,126 - 21,920,042 (+)NCBINCBI36Build 36hg18NCBI36
Build 34821,833,127 - 21,918,930NCBI
Celera820,739,441 - 20,826,178 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,319,885 - 20,406,819 (+)NCBIHuRef
CHM1_1821,978,909 - 22,065,784 (+)NCBICHM1_1
T2T-CHM13v2.0822,193,645 - 22,280,568 (+)NCBIT2T-CHM13v2.0
Xpo7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,899,566 - 71,004,075 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,891,686 - 71,004,068 (-)EnsemblGRCm39 Ensembl
GRCm381470,662,126 - 70,770,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,654,246 - 70,766,628 (-)EnsemblGRCm38mm10GRCm38
MGSCv371471,054,053 - 71,166,435 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,399,925 - 69,442,525 (-)NCBIMGSCv36mm8
Celera1468,197,866 - 68,250,683 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.44NCBI
Xpo7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81552,151,743 - 52,237,729 (-)NCBIGRCr8
mRatBN7.21545,742,053 - 45,828,050 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,742,053 - 45,828,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,859,887 - 49,945,875 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,971,417 - 51,057,407 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,830,723 - 47,916,726 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,357,845 - 52,443,055 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,357,853 - 52,443,055 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01556,081,241 - 56,166,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41551,069,113 - 51,110,710 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11551,084,892 - 51,177,719 (-)NCBI
Celera1545,420,474 - 45,505,103 (-)NCBICelera
Cytogenetic Map15p11NCBI
Xpo7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,470,988 - 45,510,025 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,470,932 - 45,508,691 (+)NCBIChiLan1.0ChiLan1.0
XPO7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,421,283 - 40,508,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,146,432 - 16,233,399 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,163,846 - 21,251,377 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,152,210 - 18,191,617 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,151,659 - 18,191,617 (+)Ensemblpanpan1.1panPan2
Xpo7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,729,494 - 12,777,124 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,802,552 - 5,841,019 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,793,382 - 5,841,019 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XPO7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,187,631 - 6,280,045 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,188,040 - 6,280,034 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,681,146 - 6,721,948 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XPO7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1819,989,776 - 20,078,145 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,037,961 - 20,076,639 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,159,606 - 22,247,973 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xpo7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,571,851 - 17,608,700 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,530,828 - 17,610,279 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in XPO7
334 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 1 17 1 6 1 6 12 8 10 4
Low 1 4 5 5 5 6 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000015931   ⟹   ENSCAFP00000014737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2535,236,784 - 35,277,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000042998   ⟹   ENSCAFP00000039214
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2535,233,034 - 35,277,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000045912   ⟹   ENSCAFP00000041056
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2535,237,093 - 35,277,124 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845049865   ⟹   ENSCAFP00845039105
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2535,447,639 - 35,539,299 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845050008   ⟹   ENSCAFP00845039212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2535,447,943 - 35,539,293 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845050282   ⟹   ENSCAFP00845039421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2535,447,943 - 35,487,794 (-)Ensembl
RefSeq Acc Id: XM_014107536   ⟹   XP_013963011
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12535,236,794 - 35,277,211 (-)NCBI
Dog10K_Boxer_Tasha2535,825,644 - 35,866,129 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038435511   ⟹   XP_038291439
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02535,447,634 - 35,487,920 (-)NCBI
RefSeq Acc Id: XM_038435512   ⟹   XP_038291440
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02535,447,634 - 35,487,919 (-)NCBI
RefSeq Acc Id: XM_038510453   ⟹   XP_038366381
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12535,392,862 - 35,433,351 (-)NCBI
RefSeq Acc Id: XM_038510454   ⟹   XP_038366382
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12535,392,862 - 35,433,350 (-)NCBI
RefSeq Acc Id: XM_038573902   ⟹   XP_038429830
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02535,402,987 - 35,443,489 (-)NCBI
RefSeq Acc Id: XM_038573903   ⟹   XP_038429831
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02535,402,987 - 35,443,488 (-)NCBI
RefSeq Acc Id: XM_038638220   ⟹   XP_038494148
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02535,247,433 - 35,287,914 (-)NCBI
RefSeq Acc Id: XM_038638221   ⟹   XP_038494149
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02535,247,433 - 35,287,913 (-)NCBI
RefSeq Acc Id: XM_844516   ⟹   XP_849609
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12535,236,794 - 35,277,211 (-)NCBI
Dog10K_Boxer_Tasha2535,825,644 - 35,866,128 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_013963011   ⟸   XM_014107536
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PGD4 (UniProtKB/TrEMBL),   A0A8I3Q5B5 (UniProtKB/TrEMBL),   A0A8C0R3K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_849609   ⟸   XM_844516
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TNI1 (UniProtKB/TrEMBL),   A0A8P0NC28 (UniProtKB/TrEMBL),   A0A8C0R3K3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000014737   ⟸   ENSCAFT00000015931
RefSeq Acc Id: ENSCAFP00000041056   ⟸   ENSCAFT00000045912
RefSeq Acc Id: ENSCAFP00000039214   ⟸   ENSCAFT00000042998
RefSeq Acc Id: XP_038366381   ⟸   XM_038510453
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038366382   ⟸   XM_038510454
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038494148   ⟸   XM_038638220
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038494149   ⟸   XM_038638221
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038291439   ⟸   XM_038435511
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PGD4 (UniProtKB/TrEMBL),   A0A8I3Q5B5 (UniProtKB/TrEMBL),   A0A8C0R3K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038291440   ⟸   XM_038435512
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TNI1 (UniProtKB/TrEMBL),   A0A8P0NC28 (UniProtKB/TrEMBL),   A0A8C0R3K3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038429830   ⟸   XM_038573902
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PGD4 (UniProtKB/TrEMBL),   A0A8C0R3K3 (UniProtKB/TrEMBL),   A0A8I3Q5B5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038429831   ⟸   XM_038573903
- Peptide Label: isoform X2
- UniProtKB: A0A8C0R3K3 (UniProtKB/TrEMBL),   A0A8C0TNI1 (UniProtKB/TrEMBL),   A0A8P0NC28 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845039421   ⟸   ENSCAFT00845050282
RefSeq Acc Id: ENSCAFP00845039212   ⟸   ENSCAFT00845050008
RefSeq Acc Id: ENSCAFP00845039105   ⟸   ENSCAFT00845049865
Protein Domains
Importin N-terminal

Promoters
RGD ID:13687798
Promoter ID:EPDNEW_C5867
Type:multiple initiation site
Name:XPO7_1
Description:exportin 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12535,277,135 - 35,277,195EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009928 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025631 UniProtKB/TrEMBL
  ENSCAFG00040023796 UniProtKB/TrEMBL
  ENSCAFG00845028066 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000015931.6 UniProtKB/TrEMBL
  ENSCAFT00000042998.3 UniProtKB/TrEMBL
  ENSCAFT00000045912.4 UniProtKB/TrEMBL
  ENSCAFT00030047416.1 UniProtKB/TrEMBL
  ENSCAFT00030047462.1 UniProtKB/TrEMBL
  ENSCAFT00040044456.1 UniProtKB/TrEMBL
  ENSCAFT00040044546.1 UniProtKB/TrEMBL
  ENSCAFT00845049865 ENTREZGENE
  ENSCAFT00845049865.1 UniProtKB/TrEMBL
  ENSCAFT00845050008.1 UniProtKB/TrEMBL
  ENSCAFT00845050282 ENTREZGENE
  ENSCAFT00845050282.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Importin-beta_N UniProtKB/TrEMBL
  XPO4/7-like UniProtKB/TrEMBL
KEGG Report cfa:477387 UniProtKB/TrEMBL
NCBI Gene XPO7 ENTREZGENE
PANTHER PTHR12596 UniProtKB/TrEMBL
  PTHR12596:SF11 UniProtKB/TrEMBL
Pfam IBN_N UniProtKB/TrEMBL
PROSITE IMPORTIN_B_NT UniProtKB/TrEMBL
SMART IBN_N UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A8C0PGD4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R3K3 ENTREZGENE
  A0A8C0TNI1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Z5T8_CANLF UniProtKB/TrEMBL
  A0A8I3PVS2_CANLF UniProtKB/TrEMBL
  A0A8I3Q5B5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QG85_CANLF UniProtKB/TrEMBL
  A0A8P0NC28 ENTREZGENE
  A0A8P0STI0_CANLF UniProtKB/TrEMBL
  A0A8P0SUW7_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0NC28 UniProtKB/TrEMBL
VGNC ID VGNC:48464 ENTREZGENE