PRM2 (protamine 2) - Rat Genome Database

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Gene: PRM2 (protamine 2) Canis lupus familiaris
Analyze
Symbol: PRM2
Name: protamine 2
RGD ID: 12286934
Description: ENCODES a protein that exhibits cadmium ion binding (ortholog); zinc ion binding (ortholog); INVOLVED IN nucleus organization (ortholog); spermatid development (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 1C (ortholog); Landau-Kleffner syndrome (ortholog); MHC class II deficiency (ortholog); FOUND IN cytoplasm (ortholog); male germ cell nucleus (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: protamine-2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,492,208 - 31,492,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,492,208 - 31,492,852 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,875,074 - 32,875,718 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0631,674,848 - 31,675,492 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl631,674,848 - 31,675,492 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,488,145 - 31,488,789 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,362,449 - 31,363,093 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0631,786,678 - 31,787,322 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PRM2DogCharcot-Marie-Tooth disease type 1C  ISOPRM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Charcot-Marie-Tooth disease type 1CClinVarPMID:28492532
PRM2DogLandau-Kleffner syndrome  ISOPRM2 (Homo sapiens)8554872ClinVar Annotator: match by term: Landau-Kleffner syndromeClinVarPMID:28492532
PRM2DogMHC class II deficiency  ISOPRM2 (Homo sapiens)8554872ClinVar Annotator: match by term: MHC class II deficiencyClinVarPMID:26271388 more ...


Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PRM2Dogcell differentiation involved_inIEAUniProtKB-KW:KW-0221150520179 UniProtGO_REF:0000043
PRM2Dogchromosome condensation involved_inIEAUniProtKB-KW:KW-0226150520179 UniProtGO_REF:0000043
PRM2Dogchromosome organization involved_inIEAInterPro:IPR000492150520179 InterProGO_REF:0000002
PRM2Dognucleus organization involved_inIBAMGI:97766 and PANTHER:PTN000482059150520179 GO_CentralGO_REF:0000033
PRM2Dognucleus organization acts_upstream_of_or_withinISOMGI:30398009068941 PMID:11326282MGIPMID:11326282
PRM2Dogspermatid development involved_inIEAInterPro:IPR000492150520179 InterProGO_REF:0000002
PRM2Dogspermatid development acts_upstream_of_or_withinISOMGI:30398009068941 PMID:11326282MGIPMID:11326282
PRM2Dogspermatid development involved_inIBAMGI:97766 and PANTHER:PTN000482059150520179 GO_CentralGO_REF:0000033
PRM2Dogspermatogenesis involved_inIEAUniProtKB-KW:KW-0744150520179 UniProtGO_REF:0000043
1 to 9 of 9 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
PRM2Dogchromosome located_inIEAUniProtKB-SubCell:SL-0468150520179 UniProtGO_REF:0000044
PRM2Dogchromosome located_inIEAUniProtKB-KW:KW-0158150520179 UniProtGO_REF:0000043
PRM2Dogcytoplasm NOT|located_inISOPrm2 (Mus musculus)9068941 PMID:8185929MGIPMID:8185929
PRM2Dogmale germ cell nucleus located_inISOPrm2 (Mus musculus)9068941 PMID:14680821MGIPMID:14680821
PRM2Dognucleosome part_ofIEAUniProtKB-KW:KW-0544150520179 UniProtGO_REF:0000043
PRM2Dognucleus is_active_inIBAMGI:97766 and PANTHER:PTN000482059150520179 GO_CentralGO_REF:0000033
PRM2Dognucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044

Molecular Function

  

PMID:18562159   PMID:22301074   PMID:30032202  



PRM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,492,208 - 31,492,852 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,492,208 - 31,492,852 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,875,074 - 32,875,718 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0631,674,848 - 31,675,492 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl631,674,848 - 31,675,492 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,488,145 - 31,488,789 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,362,449 - 31,363,093 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0631,786,678 - 31,787,322 (+)NCBIUU_Cfam_GSD_1.0
PRM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381611,275,639 - 11,276,480 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1611,275,639 - 11,276,480 (-)EnsemblGRCh38hg38GRCh38
GRCh371611,369,496 - 11,370,337 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361611,276,994 - 11,277,838 (-)NCBINCBI36Build 36hg18NCBI36
Build 341611,276,997 - 11,277,809NCBI
Celera1611,538,883 - 11,539,727 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1611,287,224 - 11,288,068 (-)NCBIHuRef
CHM1_11611,369,399 - 11,370,243 (-)NCBICHM1_1
T2T-CHM13v2.01611,311,859 - 11,312,700 (-)NCBIT2T-CHM13v2.0
Prm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,609,241 - 10,609,969 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,609,244 - 10,613,998 (-)EnsemblGRCm39 Ensembl
GRCm381610,791,377 - 10,792,105 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,791,380 - 10,796,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,791,474 - 10,792,190 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,704,959 - 10,705,675 (-)NCBIMGSCv36mm8
Celera1611,418,811 - 11,419,527 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map165.84NCBI
Prm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,383,208 - 5,383,949 (+)NCBIGRCr8
mRatBN7.2104,876,285 - 4,877,026 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl104,873,372 - 4,877,026 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,572,973 - 9,573,409 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0109,094,089 - 9,094,525 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0104,732,370 - 4,732,806 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0104,950,484 - 4,950,920 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,950,484 - 4,950,920 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0103,776,970 - 3,777,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,813,692 - 4,814,128 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1104,813,691 - 4,814,128 (+)NCBI
Celera103,897,994 - 3,898,430 (+)NCBICelera
Cytogenetic Map10q11NCBI
PRM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21811,824,801 - 11,825,700 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11615,595,263 - 15,596,125 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01610,217,586 - 10,218,446 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11611,439,417 - 11,440,265 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,439,417 - 11,440,265 (-)Ensemblpanpan1.1panPan2
PRM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl331,864,350 - 31,864,961 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1331,864,350 - 31,864,959 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2332,653,946 - 32,654,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,752,537 - 10,753,414 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl510,752,804 - 10,753,273 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,410,480 - 19,411,489 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248248,459,655 - 8,462,971 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in PRM2
3 total Variants






Ensembl Acc Id: ENSCAFT00000081333   ⟹   ENSCAFP00000060926
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl631,492,208 - 31,492,852 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845023010   ⟹   ENSCAFP00845018039
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl631,674,848 - 31,675,492 (+)Ensembl
RefSeq Acc Id: NM_001287148   ⟹   NP_001274077
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1631,492,208 - 31,492,852 (+)NCBI
Dog10K_Boxer_Tasha632,875,074 - 32,875,718 (+)NCBI
ROS_Cfam_1.0631,674,848 - 31,675,492 (+)NCBI
UMICH_Zoey_3.1631,488,145 - 31,488,789 (+)NCBI
UNSW_CanFamBas_1.0631,362,449 - 31,363,093 (+)NCBI
UU_Cfam_GSD_1.0631,786,678 - 31,787,322 (+)NCBI
Sequence:
Protein RefSeqs NP_001274077 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein DAA34861 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000060926.1
  ENSCAFP00030017703.1
  ENSCAFP00040007021.1
  ENSCAFP00845018039
  ENSCAFP00845018039.1
RefSeq Acc Id: NP_001274077   ⟸   NM_001287148
- UniProtKB: F7VJL5 (UniProtKB/TrEMBL),   A0A8C0RXS1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000060926   ⟸   ENSCAFT00000081333
Ensembl Acc Id: ENSCAFP00845018039   ⟸   ENSCAFT00845023010



1 to 17 of 17 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCAFG00000043427 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010978 UniProtKB/TrEMBL
  ENSCAFG00040004216 UniProtKB/TrEMBL
  ENSCAFG00845012943 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000081333.2 UniProtKB/TrEMBL
  ENSCAFT00030020299.1 UniProtKB/TrEMBL
  ENSCAFT00040008058.1 UniProtKB/TrEMBL
  ENSCAFT00845023010 ENTREZGENE
  ENSCAFT00845023010.1 UniProtKB/TrEMBL
InterPro PRM2 UniProtKB/TrEMBL
KEGG Report cfa:100686082 UniProtKB/TrEMBL
NCBI Gene PRM2 ENTREZGENE
PANTHER PROTAMINE-2 UniProtKB/TrEMBL
  PTHR21341 UniProtKB/TrEMBL
Pfam Protamine_P2 UniProtKB/TrEMBL
UniProt A0A8C0RXS1 ENTREZGENE, UniProtKB/TrEMBL
  F7VJL5 ENTREZGENE, UniProtKB/TrEMBL
1 to 17 of 17 rows