RNF139 (ring finger protein 139) - Rat Genome Database

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Gene: RNF139 (ring finger protein 139) Canis lupus familiaris
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Symbol: RNF139
Name: ring finger protein 139
RGD ID: 12265994
Description: ENCODES a protein that exhibits metal ion binding (inferred); protease binding (inferred); transferase activity (inferred); INVOLVED IN ERAD pathway (inferred); negative regulation of cell population proliferation (inferred); negative regulation of translation (inferred); ASSOCIATED WITH renal cell carcinoma (ortholog); trichorhinophalangeal syndrome type I (ortholog); FOUND IN Derlin-1 retrotranslocation complex (inferred); endoplasmic reticulum (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase RNF139
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11322,560,180 - 22,572,986 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1322,543,543 - 22,572,308 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1322,525,691 - 22,538,625 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01322,902,085 - 22,915,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1322,885,460 - 22,915,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11322,622,475 - 22,635,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01322,732,278 - 22,745,227 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01322,975,117 - 22,988,074 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RNF139
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11322,560,180 - 22,572,986 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1322,543,543 - 22,572,308 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1322,525,691 - 22,538,625 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01322,902,085 - 22,915,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1322,885,460 - 22,915,135 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11322,622,475 - 22,635,430 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01322,732,278 - 22,745,227 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01322,975,117 - 22,988,074 (+)NCBIUU_Cfam_GSD_1.0
RNF139
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388124,474,880 - 124,488,618 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8124,474,866 - 124,488,618 (+)EnsemblGRCh38hg38GRCh38
GRCh378125,487,121 - 125,500,859 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368125,556,189 - 125,570,040 (+)NCBINCBI36Build 36hg18NCBI36
Build 348125,556,188 - 125,570,040NCBI
Celera8121,675,173 - 121,688,974 (+)NCBICelera
Cytogenetic Map8q24.13NCBI
HuRef8120,812,471 - 120,826,584 (+)NCBIHuRef
CHM1_18125,527,264 - 125,541,113 (+)NCBICHM1_1
T2T-CHM13v2.08125,607,587 - 125,621,646 (+)NCBIT2T-CHM13v2.0
Rnf139
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391558,760,975 - 58,774,239 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1558,761,078 - 58,778,906 (+)EnsemblGRCm39 Ensembl
GRCm381558,889,229 - 58,902,390 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1558,889,229 - 58,907,057 (+)EnsemblGRCm38mm10GRCm38
MGSCv371558,720,784 - 58,733,945 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361558,719,381 - 58,730,937 (+)NCBIMGSCv36mm8
MGSCv361559,311,394 - 59,322,950 (+)NCBIMGSCv36mm8
Celera1560,427,522 - 60,431,604 (+)NCBICelera
Cytogenetic Map15D1NCBI
cM Map1525.09NCBI
Rnf139
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8792,329,201 - 92,340,386 (+)NCBIGRCr8
mRatBN7.2790,439,726 - 90,450,911 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl790,436,621 - 90,488,009 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx792,329,252 - 92,340,556 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0794,530,408 - 94,541,712 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0794,357,784 - 94,368,970 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0798,770,840 - 98,782,025 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl798,770,840 - 98,782,025 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0799,371,253 - 99,382,438 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4795,659,052 - 95,661,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1795,691,439 - 95,695,125 (+)NCBI
Celera787,205,052 - 87,216,237 (+)NCBICelera
Cytogenetic Map7q33NCBI
Rnf139
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555403,140,649 - 3,153,546 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555403,140,649 - 3,153,546 (+)NCBIChiLan1.0ChiLan1.0
RNF139
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27141,895,692 - 141,908,853 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18117,406,772 - 117,420,595 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08121,158,715 - 121,172,069 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18123,912,589 - 123,924,984 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8123,912,589 - 123,924,720 (+)Ensemblpanpan1.1panPan2
Rnf139
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530315,731,213 - 15,742,466 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647023,152,765 - 23,168,571 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647023,157,312 - 23,168,565 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RNF139
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl415,154,331 - 15,197,511 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1415,157,571 - 15,182,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2415,570,618 - 15,592,862 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RNF139
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18119,041,885 - 119,055,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8119,042,223 - 119,054,486 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603921,131,138 - 21,167,922 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rnf139
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473530,715,384 - 30,726,862 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473530,715,373 - 30,726,591 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RNF139
162 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00845020287   ⟹   ENSCAFP00845015901
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1322,885,460 - 22,914,193 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845020311   ⟹   ENSCAFP00845015920
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1322,902,107 - 22,915,135 (+)Ensembl
RefSeq Acc Id: XM_038493208   ⟹   XP_038349136
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11322,622,475 - 22,635,430 (+)NCBI
RefSeq Acc Id: XM_038555477   ⟹   XP_038411405
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01322,975,117 - 22,988,074 (+)NCBI
RefSeq Acc Id: XM_038619375   ⟹   XP_038475303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01322,732,278 - 22,745,227 (+)NCBI
RefSeq Acc Id: XM_038684983   ⟹   XP_038540911
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01322,902,085 - 22,915,033 (+)NCBI
RefSeq Acc Id: XM_846679   ⟹   XP_851772
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11322,560,180 - 22,572,986 (+)NCBI
Dog10K_Boxer_Tasha1322,525,691 - 22,538,625 (+)NCBI
Sequence:
RefSeq Acc Id: XP_851772   ⟸   XM_846679
- UniProtKB: A0A8I3NIT9 (UniProtKB/TrEMBL),   A0A8P0PCF9 (UniProtKB/TrEMBL),   A0A8C0MQ78 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038349136   ⟸   XM_038493208
RefSeq Acc Id: XP_038475303   ⟸   XM_038619375
RefSeq Acc Id: XP_038540911   ⟸   XM_038684983
- UniProtKB: A0A8I3NIT9 (UniProtKB/TrEMBL),   A0A8P0PCF9 (UniProtKB/TrEMBL),   A0A8C0MQ78 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411405   ⟸   XM_038555477
- UniProtKB: A0A8C0MQ78 (UniProtKB/TrEMBL),   A0A8I3NIT9 (UniProtKB/TrEMBL),   A0A8P0PCF9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845015901   ⟸   ENSCAFT00845020287
Ensembl Acc Id: ENSCAFP00845015920   ⟸   ENSCAFT00845020311
Promoters
RGD ID:13685603
Promoter ID:EPDNEW_C3671
Type:multiple initiation site
Name:RNF139_1
Description:ring finger protein 139
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11322,560,197 - 22,560,257EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029985 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030008268 UniProtKB/TrEMBL
  ENSCAFG00845011445 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000001597.5 UniProtKB/TrEMBL
  ENSCAFT00000084810.2 UniProtKB/TrEMBL
  ENSCAFT00030015175.1 UniProtKB/TrEMBL
  ENSCAFT00845020287.1 UniProtKB/TrEMBL
  ENSCAFT00845020311 ENTREZGENE
  ENSCAFT00845020311.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  3.40.50.150 UniProtKB/TrEMBL
  Met-10+ protein-like domains UniProtKB/TrEMBL
InterPro HRD1_E3_ubiq-ligases UniProtKB/TrEMBL
  MeTrfase_TRM5/TYW2 UniProtKB/TrEMBL
  SAM-dependent_MTases_sf UniProtKB/TrEMBL
  TRC8_N_dom UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING-CH UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report cfa:609422 UniProtKB/TrEMBL
NCBI Gene RNF139 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE RNF139 UniProtKB/TrEMBL
  RING ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam Met_10 UniProtKB/TrEMBL
  TRC8_N UniProtKB/TrEMBL
  zf-RING_2 UniProtKB/TrEMBL
PROSITE SAM_MT_TRM5_TYW2 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
  RINGv UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF53335 UniProtKB/TrEMBL
UniProt A0A8C0MQ78 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NIT9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RYJ6_CANLF UniProtKB/TrEMBL
  A0A8P0N481_CANLF UniProtKB/TrEMBL
  A0A8P0PCF9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:45632 ENTREZGENE