PLIN3 (perilipin 3) - Rat Genome Database

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Gene: PLIN3 (perilipin 3) Canis lupus familiaris
Analyze
Symbol: PLIN3
Name: perilipin 3
RGD ID: 12255265
Description: INVOLVED IN cellular response to glucose starvation (inferred); lipid droplet disassembly (inferred); lipid storage (inferred); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: M6PRBP1; mannose-6-phosphate receptor binding protein 1; perilipin-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,919,034 - 54,938,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,924,149 - 54,938,167 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,643,558 - 54,663,086 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,573,514 - 55,593,014 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,573,654 - 55,593,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,634,911 - 54,654,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,115,470 - 55,134,989 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,313,396 - 55,332,913 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
lipid droplet  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PLIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12054,919,034 - 54,938,665 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2054,924,149 - 54,938,167 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,643,558 - 54,663,086 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,573,514 - 55,593,014 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,573,654 - 55,593,905 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,634,911 - 54,654,418 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,115,470 - 55,134,989 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,313,396 - 55,332,913 (+)NCBIUU_Cfam_GSD_1.0
PLIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,838,341 - 4,867,667 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,838,341 - 4,867,694 (-)EnsemblGRCh38hg38GRCh38
GRCh37194,838,353 - 4,867,679 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,789,346 - 4,818,676 (-)NCBINCBI36Build 36hg18NCBI36
Build 34194,789,345 - 4,818,676NCBI
Celera194,776,278 - 4,805,688 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,600,618 - 4,630,086 (-)NCBIHuRef
CHM1_1194,837,970 - 4,867,350 (-)NCBICHM1_1
T2T-CHM13v2.0194,823,835 - 4,853,154 (-)NCBIT2T-CHM13v2.0
Plin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,585,962 - 56,597,511 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,584,476 - 56,599,873 (-)EnsemblGRCm39 Ensembl
GRCm381756,278,962 - 56,290,511 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,277,476 - 56,292,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv371756,418,385 - 56,429,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,912,671 - 55,924,220 (-)NCBIMGSCv36mm8
Celera1760,640,285 - 60,644,348 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.25NCBI
Plin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,198,336 - 1,210,212 (-)NCBIGRCr8
mRatBN7.291,111,178 - 1,123,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl91,102,366 - 1,123,147 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,556,854 - 1,568,721 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,904,847 - 6,916,723 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,861,896 - 5,873,763 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,769,739 - 10,781,659 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,773,901 - 10,781,109 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,761,407 - 9,773,329 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,386,939 - 7,398,847 (+)NCBICelera
Cytogenetic Map9q11NCBI
Plin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,177,906 - 4,193,299 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,177,701 - 4,190,052 (+)NCBIChiLan1.0ChiLan1.0
PLIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2209,232,586 - 9,262,057 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,461,880 - 8,491,353 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,857,506 - 3,886,274 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,808,510 - 4,835,180 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,808,512 - 4,835,180 (-)Ensemblpanpan1.1panPan2
Plin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118214,992,322 - 215,005,247 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,829,282 - 2,842,501 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,829,536 - 2,842,427 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl273,969,862 - 73,995,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1273,970,149 - 73,995,314 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Pig Cytomap2q22-q23NCBI
PLIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,538,877 - 4,565,595 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660813,581,430 - 3,610,593 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248284,950,718 - 4,961,177 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248284,949,913 - 4,961,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PLIN3
394 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000030085   ⟹   ENSCAFP00000027961
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2054,924,149 - 54,938,167 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845025527   ⟹   ENSCAFP00845020096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2055,573,654 - 55,593,905 (+)Ensembl
RefSeq Acc Id: XM_038429022   ⟹   XP_038284950
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02055,573,569 - 55,593,014 (+)NCBI
RefSeq Acc Id: XM_038429023   ⟹   XP_038284951
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02055,573,514 - 55,593,014 (+)NCBI
RefSeq Acc Id: XM_038455509   ⟹   XP_038311437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2054,643,613 - 54,663,086 (+)NCBI
RefSeq Acc Id: XM_038504631   ⟹   XP_038360559
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12054,634,966 - 54,654,418 (+)NCBI
RefSeq Acc Id: XM_038504632   ⟹   XP_038360560
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12054,634,911 - 54,654,418 (+)NCBI
RefSeq Acc Id: XM_038567702   ⟹   XP_038423630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02055,313,451 - 55,332,913 (+)NCBI
RefSeq Acc Id: XM_038567703   ⟹   XP_038423631
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02055,313,396 - 55,332,913 (+)NCBI
RefSeq Acc Id: XM_038631840   ⟹   XP_038487768
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02055,115,525 - 55,134,989 (+)NCBI
RefSeq Acc Id: XM_038631841   ⟹   XP_038487769
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02055,115,470 - 55,134,989 (+)NCBI
RefSeq Acc Id: XM_542149   ⟹   XP_542149
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12054,919,034 - 54,938,665 (+)NCBI
Dog10K_Boxer_Tasha2054,643,558 - 54,663,086 (+)NCBI
Sequence:
RefSeq Acc Id: XP_542149   ⟸   XM_542149
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q8C0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000027961   ⟸   ENSCAFT00000030085
RefSeq Acc Id: XP_038360560   ⟸   XM_038504632
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038360559   ⟸   XM_038504631
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038487769   ⟸   XM_038631841
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038487768   ⟸   XM_038631840
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038284951   ⟸   XM_038429023
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q8C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038284950   ⟸   XM_038429022
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R3N6 (UniProtKB/TrEMBL),   A0A8I3S0Q9 (UniProtKB/TrEMBL),   A0A8P0SMM1 (UniProtKB/TrEMBL),   A0A8C0Q8C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311437   ⟸   XM_038455509
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R3N6 (UniProtKB/TrEMBL),   A0A8I3S0Q9 (UniProtKB/TrEMBL),   A0A8P0SMM1 (UniProtKB/TrEMBL),   A0A8C0Q8C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423631   ⟸   XM_038567703
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q8C0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038423630   ⟸   XM_038567702
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q8C0 (UniProtKB/TrEMBL),   A0A8C0R3N6 (UniProtKB/TrEMBL),   A0A8I3S0Q9 (UniProtKB/TrEMBL),   A0A8P0SMM1 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845020096   ⟸   ENSCAFT00845025527


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018942 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040005194 UniProtKB/TrEMBL
  ENSCAFG00845014253 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000030085.5 UniProtKB/TrEMBL
  ENSCAFT00040009836.1 UniProtKB/TrEMBL
  ENSCAFT00845025527 ENTREZGENE
  ENSCAFT00845025527.1 UniProtKB/TrEMBL
Gene3D-CATH Flagellar protein FliS UniProtKB/TrEMBL
  Perilipin, alpha-beta domain UniProtKB/TrEMBL
InterPro Perilipin UniProtKB/TrEMBL
NCBI Gene PLIN3 ENTREZGENE
PANTHER PERILIPIN UniProtKB/TrEMBL
  PERILIPIN-3 UniProtKB/TrEMBL
Pfam Perilipin UniProtKB/TrEMBL
PIRSF PAT UniProtKB/TrEMBL
Superfamily-SCOP Mannose-6-phosphate receptor binding protein 1 (Tip47), C-terminal domain UniProtKB/TrEMBL
UniProt A0A8C0Q8C0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R3N6 ENTREZGENE
  A0A8I3S0Q9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SMM1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:44692 ENTREZGENE