HOXB13 (homeobox B13) - Rat Genome Database

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Gene: HOXB13 (homeobox B13) Canis lupus familiaris
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Symbol: HOXB13
Name: homeobox B13
RGD ID: 12254298
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN epithelial cell maturation involved in prostate gland development (ortholog); morphogenesis of an epithelium (ortholog); prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); cervical cancer (ortholog); ductal carcinoma in situ (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); transcription regulator complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Hox-B13
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,958,020 - 24,961,353 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,959,183 - 24,961,588 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,420,615 - 24,425,192 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,751,224 - 25,755,801 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,753,220 - 25,755,912 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,519,247 - 24,523,824 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,779,867 - 24,784,444 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,908,387 - 24,912,969 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HOXB13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1924,958,020 - 24,961,353 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl924,959,183 - 24,961,588 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha924,420,615 - 24,425,192 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0925,751,224 - 25,755,801 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl925,753,220 - 25,755,912 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1924,519,247 - 24,523,824 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0924,779,867 - 24,784,444 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0924,908,387 - 24,912,969 (-)NCBIUU_Cfam_GSD_1.0
HOXB13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381748,724,763 - 48,728,750 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1748,724,763 - 48,728,750 (-)EnsemblGRCh38hg38GRCh38
GRCh371746,802,125 - 46,806,112 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361744,157,124 - 44,161,110 (-)NCBINCBI36Build 36hg18NCBI36
Build 341744,158,866 - 44,161,084NCBI
Celera1743,256,271 - 43,260,259 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1742,171,017 - 42,175,003 (-)NCBIHuRef
CHM1_11746,868,110 - 46,872,096 (-)NCBICHM1_1
T2T-CHM13v2.01749,588,364 - 49,592,351 (-)NCBIT2T-CHM13v2.0
Hoxb13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391196,085,142 - 96,087,436 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1196,085,142 - 96,088,273 (+)EnsemblGRCm39 Ensembl
GRCm381196,194,316 - 96,196,610 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1196,194,316 - 96,197,447 (+)EnsemblGRCm38mm10GRCm38
MGSCv371196,055,675 - 96,057,913 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361196,010,451 - 96,012,689 (+)NCBIMGSCv36mm8
Celera11105,845,408 - 105,847,646 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1159.63NCBI
Hoxb13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81081,657,074 - 81,659,347 (+)NCBIGRCr8
mRatBN7.21081,160,498 - 81,162,777 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1081,160,498 - 81,162,777 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1086,109,811 - 86,112,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01085,607,837 - 85,610,110 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01081,000,052 - 81,002,325 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01084,031,955 - 84,034,228 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1084,031,955 - 84,034,228 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01083,834,616 - 83,836,889 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41084,925,520 - 84,927,793 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11084,939,948 - 84,942,992 (+)NCBI
Celera1079,927,218 - 79,929,491 (+)NCBICelera
Cytogenetic Map10q26NCBI
Hoxb13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545112,536,415 - 12,538,169 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545112,536,415 - 12,538,169 (+)NCBIChiLan1.0ChiLan1.0
HOXB13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21916,373,643 - 16,377,926 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11718,339,516 - 18,343,512 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0178,807,988 - 8,810,362 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1178,994,224 - 8,996,598 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,994,224 - 8,996,598 (+)Ensemblpanpan1.1panPan2
Hoxb13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560224,384,231 - 24,386,567 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649012,688,559 - 12,690,908 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649012,688,572 - 12,690,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXB13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1224,947,687 - 24,950,714 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11224,948,307 - 24,950,661 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21224,904,057 - 24,905,982 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HOXB13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11669,137,561 - 69,141,615 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1669,137,585 - 69,139,382 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607740,235,168 - 40,239,485 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxb13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247955,198,751 - 5,200,961 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247955,198,805 - 5,201,079 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HOXB13
20 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 31 20 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000026707   ⟹   ENSCAFP00000024813
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl924,959,183 - 24,961,588 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845017553   ⟹   ENSCAFP00845013662
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl925,753,220 - 25,755,912 (-)Ensembl
RefSeq Acc Id: XM_038485815   ⟹   XP_038341743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1924,519,247 - 24,523,824 (-)NCBI
RefSeq Acc Id: XM_038547593   ⟹   XP_038403521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0924,908,387 - 24,912,969 (-)NCBI
RefSeq Acc Id: XM_038611568   ⟹   XP_038467496
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0924,779,867 - 24,784,444 (-)NCBI
RefSeq Acc Id: XM_038676766   ⟹   XP_038532694
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0925,751,224 - 25,755,801 (-)NCBI
RefSeq Acc Id: XM_548180   ⟹   XP_548180
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1924,958,020 - 24,961,353 (-)NCBI
Dog10K_Boxer_Tasha924,420,615 - 24,425,192 (-)NCBI
Sequence:
RefSeq Acc Id: XP_548180   ⟸   XM_548180
- UniProtKB: A0A8C0LBL4 (UniProtKB/TrEMBL),   A0A8C0LWY6 (UniProtKB/TrEMBL),   A0A8I3RVJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000024813   ⟸   ENSCAFT00000026707
RefSeq Acc Id: XP_038341743   ⟸   XM_038485815
RefSeq Acc Id: XP_038467496   ⟸   XM_038611568
RefSeq Acc Id: XP_038532694   ⟸   XM_038676766
- UniProtKB: A0A8C0LBL4 (UniProtKB/TrEMBL),   A0A8C0LWY6 (UniProtKB/TrEMBL),   A0A8I3RVJ4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403521   ⟸   XM_038547593
- UniProtKB: A0A8C0LBL4 (UniProtKB/TrEMBL),   A0A8C0LWY6 (UniProtKB/TrEMBL),   A0A8I3RVJ4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845013662   ⟸   ENSCAFT00845017553
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016870 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030001808 UniProtKB/TrEMBL
  ENSCAFG00040005153 UniProtKB/TrEMBL
  ENSCAFG00845009992 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000026707.4 UniProtKB/TrEMBL
  ENSCAFT00030003293.1 UniProtKB/TrEMBL
  ENSCAFT00040009624.1 UniProtKB/TrEMBL
  ENSCAFT00845017553 ENTREZGENE
  ENSCAFT00845017553.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro AP_axis_regulatory_Homeobox UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  HoxA13_N UniProtKB/TrEMBL
KEGG Report cfa:491060 UniProtKB/TrEMBL
NCBI Gene HOXB13 ENTREZGENE
PANTHER HOMEOBOX PROTEIN HOX-B13 UniProtKB/TrEMBL
  SEGMENTATION PROTEIN FUSHI TARAZU-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  HoxA13_N UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C0LBL4 ENTREZGENE
  A0A8C0LWY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RVJ4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41750 ENTREZGENE