OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1)

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Gene: OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) Canis lupus familiaris

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Symbol:

OTUB1

Name:

OTU deubiquitinase, ubiquitin aldehyde binding 1

RGD ID:

12224315

Description:

ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); deNEDDylase activity (inferred); INVOLVED IN cellular response to interleukin-1 (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; ASSOCIATED WITH high grade glioma (ortholog); IgA glomerulonephritis (ortholog); intellectual disability (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

OTU domain, ubiquitin aldehyde binding 1; ubiquitin thioesterase OTUB1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

LOC476039

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	40,225,531 - 40,226,507 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	40,225,474 - 40,226,612 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	18	53,034,387 - 53,041,481 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	51,640,620 - 51,647,898 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	54,078,482 - 54,086,513 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	54,078,490 - 54,086,562 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	53,181,634 - 53,188,897 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	52,757,302 - 52,764,567 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	53,541,625 - 53,548,912 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

high grade glioma (ISO)

IgA glomerulonephritis (ISO)

intellectual disability (ISO)

leukocyte adhesion deficiency 3 (ISO)

lupus nephritis (ISO)

multiple endocrine neoplasia type 1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to interleukin-1 (ISO)

DNA damage response (IEA)

negative regulation of double-strand break repair (IEA)

positive regulation of TORC1 signaling (IEA)

protein deubiquitination (IEA)

protein K48-linked deubiquitination (IEA)

proteolysis (IEA)

Molecular Function

cysteine-type deubiquitinase activity (IEA)

cysteine-type peptidase activity (IEA)

deNEDDylase activity (IEA)

hydrolase activity (IEA)

protein binding (ISO)

ubiquitin binding (IEA)

ubiquitin protein ligase binding (IEA)

ubiquitin-protein transferase inhibitor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ataxia telangiectasia-mutated (ATM) signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

OTUB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	40,225,531 - 40,226,507 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	40,225,474 - 40,226,612 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1 Ensembl	18	53,034,387 - 53,041,481 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	18	51,640,620 - 51,647,898 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	18	54,078,482 - 54,086,513 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	18	54,078,490 - 54,086,562 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	18	53,181,634 - 53,188,897 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	18	52,757,302 - 52,764,567 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	18	53,541,625 - 53,548,912 (-)	NCBI		UU_Cfam_GSD_1.0

OTUB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	63,986,438 - 63,998,412 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	63,985,853 - 64,001,811 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	63,753,910 - 63,765,884 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	63,509,901 - 63,522,468 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	63,510,460 - 63,522,463	NCBI
Celera	11	61,080,100 - 61,092,667 (+)	NCBI		Celera
Cytogenetic Map	11	q13.1	NCBI
HuRef	11	60,082,024 - 60,094,513 (+)	NCBI		HuRef
CHM1_1	11	63,636,649 - 63,649,224 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	63,976,132 - 63,988,115 (+)	NCBI		T2T-CHM13v2.0

Otub1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	7,175,571 - 7,183,649 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	7,175,567 - 7,183,681 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	7,198,206 - 7,206,284 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	7,198,202 - 7,206,316 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	7,272,696 - 7,280,774 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	7,265,250 - 7,273,328 (-)	NCBI		MGSCv36	mm8
Celera	19	6,975,017 - 6,983,084 (-)	NCBI		Celera
Cytogenetic Map	19	A	NCBI
cM Map	19	5.27	NCBI

Otub1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	213,816,400 - 213,824,679 (-)	NCBI		GRCr8
mRatBN7.2	1	204,387,215 - 204,395,495 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	204,387,215 - 204,395,483 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	212,737,134 - 212,745,426 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	219,832,446 - 219,840,723 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	212,523,497 - 212,531,775 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	222,451,674 - 222,459,952 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	222,451,674 - 222,459,952 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	229,442,242 - 229,450,521 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	209,871,581 - 209,879,518 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	210,030,010 - 210,044,513 (-)	NCBI
Celera	1	201,919,929 - 201,928,118 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI

Otub1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955422	21,047,184 - 21,055,616 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955422	21,047,184 - 21,055,596 (-)	NCBI	ChiLan1.0	ChiLan1.0

OTUB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	65,212,054 - 65,225,024 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	66,257,229 - 66,270,198 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	59,342,820 - 59,355,386 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	62,690,542 - 62,702,739 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	62,690,542 - 62,706,542 (+)	Ensembl	panpan1.1		panPan2

Otub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	8,712,639 - 8,721,576 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936599	5,153,993 - 5,173,046 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936599	5,154,988 - 5,163,919 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OTUB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	8,087,829 - 8,095,609 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	8,088,528 - 8,095,555 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	7,205,414 - 7,212,452 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OTUB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	10,247,260 - 10,271,026 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666038	107,583,188 - 107,596,053 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Otub1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624767	22,278,572 - 22,289,640 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624767	22,278,572 - 22,289,576 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in OTUB1
21 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001251947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038423483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO595103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN345901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN869994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000037	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000021068 ⟹ ENSCAFP00000055110

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	3	40,225,474 - 40,226,612 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000023395 ⟹ ENSCAFP00000021726

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	18	53,034,387 - 53,041,481 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845054741 ⟹ ENSCAFP00845043058

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	54,078,490 - 54,086,562 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845054745 ⟹ ENSCAFP00845043062

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	18	54,078,490 - 54,086,562 (-)	Ensembl

RefSeq Acc Id:

NM_001251947 ⟹ NP_001238876

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	3	40,225,531 - 40,226,507 (-)	NCBI
Dog10K_Boxer_Tasha	18	51,640,620 - 51,647,898 (-)	NCBI
ROS_Cfam_1.0	18	54,079,247 - 54,086,513 (-)	NCBI
UMICH_Zoey_3.1	18	53,181,634 - 53,188,897 (-)	NCBI
UNSW_CanFamBas_1.0	18	52,757,302 - 52,764,567 (-)	NCBI
UU_Cfam_GSD_1.0	18	53,541,625 - 53,548,912 (-)	NCBI

Sequence:

show sequence

GCTGTTTAAAGATGGCGGCGGAGGAGCCTCACCAGCAGAAGCAGGAGCCGCTCGGCAGCGACTC
CGAAGGTGTTAACTGTCTTGCTTATGATGAAGCCATCATGGCTCAGCAGGACCGAATTCAGCAA
GAGATTGCTGTGCAGAACCCTCTGGTCTCAGAGCGGCTGGAGCTTTCGGTCCTGTACAAGGAGT
ATGCTGAGGATGACAACATCTATCAACAGAAGATCAAGGACCTCCACAAAAAGTACTCCTACAT
CCGCAAGACCAGGCCTGATGGAAACTGTTTCTACCGAGCTTTCGGATTCTCCCACTTGGAGGCG
CTGCTGGATGACAGCAAGGAATTGCAGCGGTTTAAGGCTGTGTCTGCCAAGAGCAAAGAGGACC
TGGTGTCCCAGGGCTTCACTGAATTCACAATCGAGGATTTCCACAACACGTTCATGGACCTGAT
CGAGCAGGTGGAGAAGCAGACCTCTGTAGCTGACCTGCTGGCCTCCTTCAACGACCAGAGTACC
TCGGACTACCTGGTGGTGTACCTGCGGCTGCTCACCTCCGGCTACCTGCAGCGCGAGAGCAAGT
TCTTCGAGCACTTCATCGAGGGCGGGCGGACAGTCAAGGAGTTCTGCCAGCAGGAGGTGGAGCC
CATGTGCAAGGAGAGCGACCACATTCACATCATCGCACTGGCCCAGGCTCTGAGCGTCTCCATC
CAGGTGGAGTACATGGACCGCGGCGAGGGCGGCACCACCAACCCGCACATCTTCCCCGAGGGCT
CTGAGCCCAAGGTGTACCTTCTCTACCGGCCTGGACACTACGATATCCTCTACAAATAGGGCTG
GCCCCGGCCTCCTGCTGCCCTGTCTGCCCTCCCCTCTGCCGGGCGCTAGACATGTACAGAAGTT
TTTTGTGGTTGTAAATGGTCATATTTCACTCCCTCCTCCACTTTCCCTGTCACGCAACCTTCCA
CATTTTATTAAAGGGGATGCTGGTGGTGA

hide sequence

RefSeq Acc Id:

XM_038423483 ⟹ XP_038279411

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	18	54,078,482 - 54,085,891 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001238876	(Get FASTA)	NCBI Sequence Viewer
	XP_038279411	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000021726.5
	ENSCAFP00000068926.1
	ENSCAFP00030016205.1
	ENSCAFP00030016230.1
	ENSCAFP00040024355.1
	ENSCAFP00040024415.1
	ENSCAFP00040024453.1
	ENSCAFP00845043058
	ENSCAFP00845043058.1
	ENSCAFP00845043062.1

RefSeq Acc Id:

NP_001238876 ⟸ NM_001251947

- UniProtKB:

A0A8C0SNM8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAEEPHQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAED
DNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQ
GFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEH
FIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEPK
VYLLYRPGHYDILYK

hide sequence

Ensembl Acc Id:

ENSCAFP00000055110 ⟸ ENSCAFT00000021068

Ensembl Acc Id:

ENSCAFP00000021726 ⟸ ENSCAFT00000023395

RefSeq Acc Id:	XP_038279411 ⟸ XM_038423483
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0SNM8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845043062 ⟸ ENSCAFT00845054745

Ensembl Acc Id:

ENSCAFP00845043058 ⟸ ENSCAFT00845054741

Protein Domains

OTU

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000013279	Ensembl
	ENSCAFG00000014729	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030009988	UniProtKB/TrEMBL
	ENSCAFG00040015186	UniProtKB/TrEMBL
	ENSCAFG00845030788	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000023395.5	UniProtKB/TrEMBL
	ENSCAFT00000106338.1	UniProtKB/TrEMBL
	ENSCAFT00030018570.1	UniProtKB/TrEMBL
	ENSCAFT00030018598.1	UniProtKB/TrEMBL
	ENSCAFT00040028041.1	UniProtKB/TrEMBL
	ENSCAFT00040028105.1	UniProtKB/TrEMBL
	ENSCAFT00040028146.1	UniProtKB/TrEMBL
	ENSCAFT00845054741	ENTREZGENE
	ENSCAFT00845054741.1	UniProtKB/TrEMBL
	ENSCAFT00845054745.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1300.20	UniProtKB/TrEMBL
	3.30.200.60	UniProtKB/TrEMBL
InterPro	OTU_dom	UniProtKB/TrEMBL
	Otubain	UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/TrEMBL
	Peptidase_C65_otubain	UniProtKB/TrEMBL
	Peptidase_C65_otubain_sub1	UniProtKB/TrEMBL
	Peptidase_C65_otubain_sub2	UniProtKB/TrEMBL
NCBI Gene	OTUB1	ENTREZGENE
PANTHER	PTHR12931	UniProtKB/TrEMBL
	PTHR12931:SF19	UniProtKB/TrEMBL
Pfam	Peptidase_C65	UniProtKB/TrEMBL
PIRSF	Ubiquitin_thioesterase_Otubain	UniProtKB/TrEMBL
PROSITE	OTU	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54001	UniProtKB/TrEMBL
UniProt	A0A8C0MVM6_CANLF	UniProtKB/TrEMBL
	A0A8C0SNI6_CANLF	UniProtKB/TrEMBL
	A0A8C0SNM8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SRF7_CANLF	UniProtKB/TrEMBL
	A0A8I3Q5J1_CANLF	UniProtKB/TrEMBL
	A0A8I3QV57_CANLF	UniProtKB/TrEMBL
	A0A8P0NGC3_CANLF	UniProtKB/TrEMBL
VGNC ID	VGNC:49784	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-01-14	OTUB1	OTU deubiquitinase, ubiquitin aldehyde binding 1	OTUB1	OTU deubiquitinase, ubiquitin aldehyde binding 1	Data merged from RGD:12423523	737654	PROVISIONAL
2021-01-12	OTUB1	OTU deubiquitinase, ubiquitin aldehyde binding 1	OTUB1	OTU domain, ubiquitin aldehyde binding 1	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

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Imported Disease Annotations - ClinVar

RGD Manual Annotations