GPAA1 (glycosylphosphatidylinositol anchor attachment 1) - Rat Genome Database

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Gene: GPAA1 (glycosylphosphatidylinositol anchor attachment 1) Canis lupus familiaris
Analyze
Symbol: GPAA1
Name: glycosylphosphatidylinositol anchor attachment 1
RGD ID: 12215829
Description: ENCODES a protein that exhibits GPI anchor binding (ortholog); INVOLVED IN attachment of GPI anchor to protein (inferred); ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); genetic disease (ortholog); FOUND IN centrosome (inferred); cytosol (inferred); endoplasmic reticulum (inferred); INTERACTS WITH mocetinostat
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glycosylphosphatidylinositol anchor attachment 1 (GPAA1); glycosylphosphatidylinositol anchor attachment 1 protein; glycosylphosphatidylinositol anchor attachment protein 1 homolog; GPAA1P anchor attachment protein 1 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,577,162 - 37,580,346 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,576,354 - 37,580,345 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,540,819 - 37,543,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,053,394 - 38,056,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,053,345 - 38,069,424 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,725,487 - 37,728,658 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,853,701 - 37,856,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,330,285 - 38,333,466 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
mocetinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:10393431   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GPAA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,577,162 - 37,580,346 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,576,354 - 37,580,345 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,540,819 - 37,543,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01338,053,394 - 38,056,568 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1338,053,345 - 38,069,424 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,725,487 - 37,728,658 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,853,701 - 37,856,859 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01338,330,285 - 38,333,466 (+)NCBIUU_Cfam_GSD_1.0
GPAA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388144,082,634 - 144,086,216 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8144,082,337 - 144,093,149 (+)EnsemblGRCh38hg38GRCh38
GRCh378145,137,537 - 145,141,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368145,209,512 - 145,213,107 (+)NCBINCBI36Build 36hg18NCBI36
Build 348145,209,526 - 145,213,102NCBI
Celera8141,475,157 - 141,478,683 (+)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8140,413,426 - 140,417,021 (+)NCBIHuRef
CHM1_18145,177,776 - 145,181,371 (+)NCBICHM1_1
T2T-CHM13v2.08145,243,485 - 145,247,067 (+)NCBIT2T-CHM13v2.0
Gpaa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391576,215,494 - 76,219,099 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1576,215,431 - 76,219,107 (+)EnsemblGRCm39 Ensembl
GRCm381576,331,294 - 76,334,900 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1576,331,231 - 76,334,907 (+)EnsemblGRCm38mm10GRCm38
MGSCv371576,161,724 - 76,165,329 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361576,158,549 - 76,162,154 (+)NCBIMGSCv36mm8
Celera1577,831,354 - 77,834,959 (+)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.72NCBI
Gpaa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,932,556 - 109,936,139 (+)NCBIGRCr8
mRatBN7.27108,051,896 - 108,055,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7108,051,861 - 108,055,484 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,795,563 - 109,799,146 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07112,019,257 - 112,022,840 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,977,711 - 111,981,294 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07117,394,367 - 117,397,950 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7117,394,372 - 117,397,956 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07117,381,997 - 117,385,580 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47114,378,978 - 114,382,561 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17114,413,207 - 114,416,790 (+)NCBI
Celera7104,404,246 - 104,407,829 (+)NCBICelera
Cytogenetic Map7q34NCBI
Gpaa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,735,463 - 2,738,956 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,735,463 - 2,738,956 (+)NCBIChiLan1.0ChiLan1.0
LOC100979844
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21217,768,812 - 17,773,809 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A17,771,585 - 17,781,036 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A91,716,647 - 91,721,082 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A111,487,498 - 111,510,259 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,840,524 - 143,845,352 (+)Ensemblpanpan1.1panPan2
Gpaa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303666,664 - 670,968 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,092,855 - 8,096,074 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,092,758 - 8,096,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPAA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4614,601 - 618,241 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14614,596 - 618,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24767,760 - 771,431 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPAA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18138,295,851 - 138,299,461 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8138,296,002 - 138,299,370 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660391,573,518 - 1,577,182 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpaa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473512,739,750 - 12,743,223 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473512,739,750 - 12,743,219 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPAA1
59 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038423566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038494072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038494073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038555107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038555108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038618990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038684593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_532350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB017264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000002378   ⟹   ENSCAFP00000002200
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1337,577,152 - 37,580,345 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000045933   ⟹   ENSCAFP00000042355
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1337,577,265 - 37,580,345 (+)Ensembl
Ensembl Acc Id: ENSCAFT00000081541   ⟹   ENSCAFP00000044307
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1337,576,354 - 37,580,345 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845013567   ⟹   ENSCAFP00845010533
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1338,053,345 - 38,056,568 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845013661   ⟹   ENSCAFP00845010608
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1338,053,374 - 38,069,424 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845013788   ⟹   ENSCAFP00845010700
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1338,053,440 - 38,058,073 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845013873   ⟹   ENSCAFP00845010760
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1338,053,487 - 38,069,424 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845013975   ⟹   ENSCAFP00845010828
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1338,053,487 - 38,056,568 (+)Ensembl
RefSeq Acc Id: XM_038423566   ⟹   XP_038279494
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1337,540,819 - 37,543,992 (+)NCBI
RefSeq Acc Id: XM_038494072   ⟹   XP_038350000
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,725,487 - 37,728,658 (+)NCBI
RefSeq Acc Id: XM_038494073   ⟹   XP_038350001
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,725,487 - 37,728,658 (+)NCBI
RefSeq Acc Id: XM_038555107   ⟹   XP_038411035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01338,330,285 - 38,333,466 (+)NCBI
RefSeq Acc Id: XM_038555108   ⟹   XP_038411036
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01338,330,285 - 38,333,466 (+)NCBI
RefSeq Acc Id: XM_038618989   ⟹   XP_038474917
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,853,701 - 37,856,859 (+)NCBI
RefSeq Acc Id: XM_038618990   ⟹   XP_038474918
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,853,701 - 37,856,859 (+)NCBI
RefSeq Acc Id: XM_038684592   ⟹   XP_038540520
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01338,053,394 - 38,056,568 (+)NCBI
RefSeq Acc Id: XM_038684593   ⟹   XP_038540521
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01338,053,394 - 38,056,568 (+)NCBI
RefSeq Acc Id: XM_532350   ⟹   XP_532350
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11337,577,162 - 37,580,346 (+)NCBI
Dog10K_Boxer_Tasha1337,540,819 - 37,543,992 (+)NCBI
Sequence:
RefSeq Acc Id: XP_532350   ⟸   XM_532350
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R3N4 (UniProtKB/TrEMBL),   A0A8C0SGN2 (UniProtKB/TrEMBL),   A0A8P0S7G3 (UniProtKB/TrEMBL),   A0A8C0PPI5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000042355   ⟸   ENSCAFT00000045933
Ensembl Acc Id: ENSCAFP00000002200   ⟸   ENSCAFT00000002378
Ensembl Acc Id: ENSCAFP00000044307   ⟸   ENSCAFT00000081541
RefSeq Acc Id: XP_038350000   ⟸   XM_038494072
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038350001   ⟸   XM_038494073
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038474917   ⟸   XM_038618989
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038474918   ⟸   XM_038618990
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038540520   ⟸   XM_038684592
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R3N4 (UniProtKB/TrEMBL),   A0A8C0SGN2 (UniProtKB/TrEMBL),   A0A8P0S7G3 (UniProtKB/TrEMBL),   A0A8C0PPI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038540521   ⟸   XM_038684593
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038279494   ⟸   XM_038423566
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038411035   ⟸   XM_038555107
- Peptide Label: isoform X1
- UniProtKB: A0A8C0PPI5 (UniProtKB/TrEMBL),   A0A8C0R3N4 (UniProtKB/TrEMBL),   A0A8C0SGN2 (UniProtKB/TrEMBL),   A0A8P0S7G3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411036   ⟸   XM_038555108
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845010828   ⟸   ENSCAFT00845013975
Ensembl Acc Id: ENSCAFP00845010608   ⟸   ENSCAFT00845013661
Ensembl Acc Id: ENSCAFP00845010700   ⟸   ENSCAFT00845013788
Ensembl Acc Id: ENSCAFP00845010760   ⟸   ENSCAFT00845013873
Ensembl Acc Id: ENSCAFP00845010533   ⟸   ENSCAFT00845013567

Promoters
RGD ID:13685627
Promoter ID:EPDNEW_C3695
Type:initiation region
Name:GPAA1_1
Description:glycosylphosphatidylinositol anchor attachment 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11337,577,171 - 37,577,231EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001523 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030025525 UniProtKB/TrEMBL
  ENSCAFG00040012682 UniProtKB/TrEMBL
  ENSCAFG00845007719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000002378.5 UniProtKB/TrEMBL
  ENSCAFT00000045933.4 UniProtKB/TrEMBL
  ENSCAFT00030047136.1 UniProtKB/TrEMBL
  ENSCAFT00030047159.1 UniProtKB/TrEMBL
  ENSCAFT00040023582.1 UniProtKB/TrEMBL
  ENSCAFT00040023672.1 UniProtKB/TrEMBL
  ENSCAFT00040023771.1 UniProtKB/TrEMBL
  ENSCAFT00845013567 ENTREZGENE
  ENSCAFT00845013567.1 UniProtKB/TrEMBL
  ENSCAFT00845013661.1 UniProtKB/TrEMBL
  ENSCAFT00845013788.1 UniProtKB/TrEMBL
  ENSCAFT00845013975.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.760.10 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro Cyt_c-like_dom_sf UniProtKB/TrEMBL
  Cyt_c1 UniProtKB/TrEMBL
  Gaa1 UniProtKB/TrEMBL
NCBI Gene GPAA1 ENTREZGENE
PANTHER GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN UniProtKB/TrEMBL
  PTHR13304 UniProtKB/TrEMBL
Pfam Cytochrom_C1 UniProtKB/TrEMBL
  Gaa1 UniProtKB/TrEMBL
PIRSF GAA1 UniProtKB/TrEMBL
PRINTS CYTOCHROMEC1 UniProtKB/TrEMBL
Superfamily-SCOP SSF46626 UniProtKB/TrEMBL
UniProt A0A8C0PG67_CANLF UniProtKB/TrEMBL
  A0A8C0PPI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R3N4 ENTREZGENE
  A0A8C0SFV7_CANLF UniProtKB/TrEMBL
  A0A8C0SGN2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SHI0_CANLF UniProtKB/TrEMBL
  A0A8I3N387_CANLF UniProtKB/TrEMBL
  A0A8I3N3K0_CANLF UniProtKB/TrEMBL
  A0A8I3N754_CANLF UniProtKB/TrEMBL
  A0A8I3RU32_CANLF UniProtKB/TrEMBL
  A0A8P0S7G3 ENTREZGENE
  Q9XTA6_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0S7G3 UniProtKB/TrEMBL
VGNC ID VGNC:41358 ENTREZGENE