TCTN3 (tectonic family member 3) - Rat Genome Database

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Gene: TCTN3 (tectonic family member 3) Canis lupus familiaris
Analyze
Symbol: TCTN3
Name: tectonic family member 3
RGD ID: 12184537
Description: INVOLVED IN cell projection organization (inferred); cilium assembly (inferred); positive regulation of apoptotic process (inferred); ASSOCIATED WITH agammaglobulinemia 4 (ortholog); Developmental Disabilities (ortholog); genetic disease (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tectonic-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1289,155,758 - 9,181,721 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl289,156,797 - 9,181,731 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha289,330,959 - 9,357,567 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0289,417,327 - 9,443,946 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl289,417,888 - 9,444,387 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1289,133,791 - 9,160,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0289,192,795 - 9,219,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0289,336,550 - 9,363,162 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TCTN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1289,155,758 - 9,181,721 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl289,156,797 - 9,181,731 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha289,330,959 - 9,357,567 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0289,417,327 - 9,443,946 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl289,417,888 - 9,444,387 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1289,133,791 - 9,160,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0289,192,795 - 9,219,907 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0289,336,550 - 9,363,162 (-)NCBIUU_Cfam_GSD_1.0
TCTN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381095,663,401 - 95,693,927 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1095,659,823 - 95,694,143 (-)EnsemblGRCh38hg38GRCh38
GRCh371097,423,158 - 97,453,684 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361097,413,163 - 97,443,890 (-)NCBINCBI36Build 36hg18NCBI36
Build 341097,413,162 - 97,443,701NCBI
Celera1091,164,350 - 91,195,122 (-)NCBICelera
Cytogenetic Map10q24.1NCBI
HuRef1091,050,833 - 91,081,585 (-)NCBIHuRef
CHM1_11097,705,000 - 97,735,751 (-)NCBICHM1_1
T2T-CHM13v2.01096,542,501 - 96,573,034 (-)NCBIT2T-CHM13v2.0
Tctn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391940,584,890 - 40,600,768 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1940,584,890 - 40,600,677 (-)EnsemblGRCm39 Ensembl
GRCm381940,596,446 - 40,612,324 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1940,596,446 - 40,612,233 (-)EnsemblGRCm38mm10GRCm38
MGSCv371940,670,936 - 40,686,705 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361940,649,757 - 40,665,526 (-)NCBIMGSCv36mm8
Celera1941,398,356 - 41,414,120 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1934.25NCBI
Tctn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,363,428 - 249,374,698 (-)NCBIGRCr8
mRatBN7.21239,414,003 - 239,425,273 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,415,203 - 239,425,272 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1247,549,857 - 247,561,127 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01254,253,534 - 254,264,813 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01246,906,571 - 246,917,850 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01259,681,435 - 259,691,881 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,097,455 - 259,106,948 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1259,682,249 - 259,691,742 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01267,124,918 - 267,135,070 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41245,725,786 - 245,735,594 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1235,260,289 - 235,270,735 (-)NCBICelera
Cytogenetic Map1q54NCBI
Tctn3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555071,973,500 - 1,994,609 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555071,972,645 - 1,993,967 (-)NCBIChiLan1.0ChiLan1.0
TCTN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28107,566,996 - 107,597,074 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110107,572,295 - 107,602,393 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01092,274,003 - 92,304,093 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11095,780,315 - 95,810,271 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1095,780,315 - 95,810,271 (-)Ensemblpanpan1.1panPan2
Tctn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721337,683,854 - 37,711,365 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366363,722,950 - 3,751,557 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366363,722,985 - 3,750,440 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TCTN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14107,230,934 - 107,263,344 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114107,230,820 - 107,263,364 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214116,865,469 - 116,897,218 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TCTN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1988,829,750 - 88,859,580 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl988,829,749 - 88,859,547 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604849,697,411 - 49,727,748 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tctn3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247376,984,234 - 7,012,142 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247376,980,716 - 7,011,681 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TCTN3
370 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 5 22 6 6 6 6 12 8 10 6
Below cutoff 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022412017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022412018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038440092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038440094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038440095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038514700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038514701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038514702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038578340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038578341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038578342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038642508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_845574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000013361   ⟹   ENSCAFP00000012364
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl289,156,797 - 9,181,731 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000069679   ⟹   ENSCAFP00000043367
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl289,156,797 - 9,181,731 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845044626   ⟹   ENSCAFP00845034964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl289,417,888 - 9,444,387 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845044766   ⟹   ENSCAFP00845035080
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl289,417,888 - 9,443,955 (-)Ensembl
RefSeq Acc Id: XM_022412017   ⟹   XP_022267725
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1289,161,158 - 9,181,721 (-)NCBI
Dog10K_Boxer_Tasha289,336,991 - 9,357,567 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022412018   ⟹   XP_022267726
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1289,155,758 - 9,181,720 (-)NCBI
Dog10K_Boxer_Tasha289,330,959 - 9,357,567 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038440092   ⟹   XP_038296020
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0289,417,328 - 9,443,946 (-)NCBI
RefSeq Acc Id: XM_038440094   ⟹   XP_038296022
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0289,423,359 - 9,443,946 (-)NCBI
RefSeq Acc Id: XM_038440095   ⟹   XP_038296023
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0289,417,327 - 9,443,946 (-)NCBI
RefSeq Acc Id: XM_038514700   ⟹   XP_038370628
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1289,133,792 - 9,160,393 (-)NCBI
RefSeq Acc Id: XM_038514701   ⟹   XP_038370629
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1289,139,822 - 9,160,393 (-)NCBI
RefSeq Acc Id: XM_038514702   ⟹   XP_038370630
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1289,133,791 - 9,160,393 (-)NCBI
RefSeq Acc Id: XM_038578340   ⟹   XP_038434268
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0289,336,551 - 9,363,162 (-)NCBI
RefSeq Acc Id: XM_038578341   ⟹   XP_038434269
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0289,342,585 - 9,363,162 (-)NCBI
RefSeq Acc Id: XM_038578342   ⟹   XP_038434270
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0289,336,550 - 9,363,162 (-)NCBI
RefSeq Acc Id: XM_038642506   ⟹   XP_038498434
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0289,192,796 - 9,219,907 (-)NCBI
RefSeq Acc Id: XM_038642507   ⟹   XP_038498435
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0289,198,581 - 9,219,907 (-)NCBI
RefSeq Acc Id: XM_038642508   ⟹   XP_038498436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0289,192,795 - 9,219,907 (-)NCBI
RefSeq Acc Id: XM_845574   ⟹   XP_850667
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1289,155,758 - 9,181,720 (-)NCBI
Dog10K_Boxer_Tasha289,330,960 - 9,357,567 (-)NCBI
Sequence:
RefSeq Acc Id: XP_850667   ⟸   XM_845574
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JWW0 (UniProtKB/TrEMBL),   A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022267726   ⟸   XM_022412018
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022267725   ⟸   XM_022412017
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000043367   ⟸   ENSCAFT00000069679
RefSeq Acc Id: ENSCAFP00000012364   ⟸   ENSCAFT00000013361
RefSeq Acc Id: XP_038370630   ⟸   XM_038514702
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038370628   ⟸   XM_038514700
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038370629   ⟸   XM_038514701
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038498436   ⟸   XM_038642508
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038498434   ⟸   XM_038642506
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038498435   ⟸   XM_038642507
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038296023   ⟸   XM_038440095
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038296020   ⟸   XM_038440092
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JWW0 (UniProtKB/TrEMBL),   A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038296022   ⟸   XM_038440094
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038434270   ⟸   XM_038578342
- Peptide Label: isoform X3
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038434268   ⟸   XM_038578340
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JWW0 (UniProtKB/TrEMBL),   A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038434269   ⟸   XM_038578341
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TRB8 (UniProtKB/TrEMBL),   A0A8I3PPE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845035080   ⟸   ENSCAFT00845044766
RefSeq Acc Id: ENSCAFP00845034964   ⟸   ENSCAFT00845044626
Protein Domains
Tectonic

Promoters
RGD ID:13688274
Promoter ID:EPDNEW_C6342
Type:initiation region
Name:TCTN3_1
Description:tectonic family member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1289,181,688 - 9,181,748EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000008406 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040023697 UniProtKB/TrEMBL
  ENSCAFG00845025277 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000013361.5 UniProtKB/TrEMBL
  ENSCAFT00000069679.2 UniProtKB/TrEMBL
  ENSCAFT00000099500.1 UniProtKB/TrEMBL
  ENSCAFT00040044119.1 UniProtKB/TrEMBL
  ENSCAFT00040044152.1 UniProtKB/TrEMBL
  ENSCAFT00845044626 ENTREZGENE
  ENSCAFT00845044626.1 UniProtKB/TrEMBL
  ENSCAFT00845044766.1 UniProtKB/TrEMBL
InterPro Tectonic UniProtKB/TrEMBL
  Tectonic_dom UniProtKB/TrEMBL
NCBI Gene TCTN3 ENTREZGENE
PANTHER PTHR14611 UniProtKB/TrEMBL
  TECTONIC-3 UniProtKB/TrEMBL
Pfam DUF1619 UniProtKB/TrEMBL
UniProt A0A8C0JWW0 ENTREZGENE
  A0A8C0TMV4_CANLF UniProtKB/TrEMBL
  A0A8C0TRB8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PPE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PXV1_CANLF UniProtKB/TrEMBL
  A0A8P0PLN8_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:47215 ENTREZGENE