CDH15 (cadherin 15) - Rat Genome Database

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Gene: CDH15 (cadherin 15) Canis lupus familiaris
Analyze
Symbol: CDH15
Name: cadherin 15
RGD ID: 12180425
Description: ENCODES a protein that exhibits cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN adherens junction organization (inferred); calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (inferred); cell adhesion (inferred); ASSOCIATED WITH 16Q24.3 Microdeletion Syndrome (ortholog); autosomal dominant intellectual developmental disorder 1 (ortholog); autosomal dominant intellectual developmental disorder 3 (ortholog); FOUND IN adherens junction (inferred); catenin complex (inferred); caveola (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cadherin 15, M-cadherin (myotubule); cadherin-15
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,258,451 - 64,277,184 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,258,741 - 64,277,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,270,039 - 64,288,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,485,448 - 64,504,164 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,485,449 - 64,504,142 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,504,817 - 64,523,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,342,688 - 64,361,396 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,749,610 - 64,768,354 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDH15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1564,258,451 - 64,277,184 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl564,258,741 - 64,277,190 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha564,270,039 - 64,288,790 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0564,485,448 - 64,504,164 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl564,485,449 - 64,504,142 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1564,504,817 - 64,523,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0564,342,688 - 64,361,396 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0564,749,610 - 64,768,354 (-)NCBIUU_Cfam_GSD_1.0
CDH15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,171,748 - 89,195,492 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,171,748 - 89,195,492 (+)EnsemblGRCh38hg38GRCh38
GRCh371689,238,156 - 89,261,900 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,765,664 - 87,789,401 (+)NCBINCBI36Build 36hg18NCBI36
Build 341687,765,663 - 87,789,400NCBI
Celera1674,303,777 - 74,327,730 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,937,029 - 74,960,595 (+)NCBIHuRef
CHM1_11690,649,453 - 90,672,880 (+)NCBICHM1_1
T2T-CHM13v2.01695,251,870 - 95,275,698 (+)NCBIT2T-CHM13v2.0
Cdh15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,575,113 - 123,594,136 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8123,574,705 - 123,594,136 (+)EnsemblGRCm39 Ensembl
GRCm388122,848,374 - 122,867,397 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8122,847,966 - 122,867,397 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,372,274 - 125,391,297 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368125,734,056 - 125,753,487 (+)NCBIMGSCv36mm8
Celera8127,083,268 - 127,101,936 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map871.99NCBI
Cdh15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81967,812,169 - 67,834,986 (+)NCBIGRCr8
mRatBN7.21950,903,757 - 50,927,151 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1950,903,638 - 50,927,105 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1957,700,635 - 57,720,963 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01958,381,063 - 58,401,389 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01960,599,254 - 60,619,583 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01955,669,661 - 55,689,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1955,669,626 - 55,689,992 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,373,237 - 66,396,730 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,182,536 - 53,194,779 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11953,187,414 - 53,199,660 (+)NCBI
Celera1950,143,657 - 50,163,976 (+)NCBICelera
Cytogenetic Map19q12NCBI
Cdh15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555412,881,525 - 2,893,653 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555412,881,374 - 2,893,885 (+)NCBIChiLan1.0ChiLan1.0
CDH15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21898,955,721 - 98,979,974 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,871,254 - 104,895,421 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl1689,543,888 - 89,562,843 (+)Ensemblpanpan1.1panPan2
Cdh15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,921,433 - 24,937,975 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936641675,322 - 691,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936641675,317 - 691,386 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDH15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6636,377 - 652,165 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16636,350 - 652,260 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26923,747 - 932,723 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDH15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,542,174 - 74,563,753 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,550,637 - 74,563,850 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666047974,596 - 995,473 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdh15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746605,012 - 617,582 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624746603,723 - 617,616 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDH15
227 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 5 3 4 6 3 3 2
Below cutoff 4 18 6 6 6 2 9 8 7 4

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022419081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038476874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038525161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038538036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038602169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038666777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_536750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000031571   ⟹   ENSCAFP00000029392
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl564,258,741 - 64,277,190 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000066418   ⟹   ENSCAFP00000047336
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl564,258,741 - 64,277,190 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004744   ⟹   ENSCAFP00845003794
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl564,485,449 - 64,504,142 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004756   ⟹   ENSCAFP00845003806
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl564,485,449 - 64,504,142 (-)Ensembl
RefSeq Acc Id: XM_038476873   ⟹   XP_038332801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1564,504,817 - 64,523,569 (-)NCBI
RefSeq Acc Id: XM_038476874   ⟹   XP_038332802
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1564,504,817 - 64,523,568 (-)NCBI
RefSeq Acc Id: XM_038525157   ⟹   XP_038381085
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha564,270,039 - 64,288,790 (-)NCBI
RefSeq Acc Id: XM_038525161   ⟹   XP_038381089
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha564,270,039 - 64,288,789 (-)NCBI
RefSeq Acc Id: XM_038538035   ⟹   XP_038393963
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0564,749,610 - 64,768,354 (-)NCBI
RefSeq Acc Id: XM_038538036   ⟹   XP_038393964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0564,749,610 - 64,768,353 (-)NCBI
RefSeq Acc Id: XM_038602168   ⟹   XP_038458096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0564,342,688 - 64,361,396 (-)NCBI
RefSeq Acc Id: XM_038602169   ⟹   XP_038458097
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0564,342,688 - 64,361,395 (-)NCBI
RefSeq Acc Id: XM_038666776   ⟹   XP_038522704
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0564,485,448 - 64,504,164 (-)NCBI
RefSeq Acc Id: XM_038666777   ⟹   XP_038522705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0564,485,448 - 64,504,163 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000047336   ⟸   ENSCAFT00000066418
RefSeq Acc Id: ENSCAFP00000029392   ⟸   ENSCAFT00000031571
RefSeq Acc Id: XP_038332801   ⟸   XM_038476873
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038332802   ⟸   XM_038476874
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038458096   ⟸   XM_038602168
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038458097   ⟸   XM_038602169
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038522704   ⟸   XM_038666776
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL),   A0A8I3MHF7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038522705   ⟸   XM_038666777
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381085   ⟸   XM_038525157
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL),   A0A8C0Z6N3 (UniProtKB/TrEMBL),   A0A8P0SNR7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038381089   ⟸   XM_038525161
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038393963   ⟸   XM_038538035
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL),   A0A8C0NDE2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038393964   ⟸   XM_038538036
- Peptide Label: isoform X2
- UniProtKB: A0A8C0JX43 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845003794   ⟸   ENSCAFT00845004744
RefSeq Acc Id: ENSCAFP00845003806   ⟸   ENSCAFT00845004756
Protein Domains
Cadherin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000019846 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013555 UniProtKB/TrEMBL
  ENSCAFG00040025100 UniProtKB/TrEMBL
  ENSCAFG00845002672 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000031571.5 UniProtKB/TrEMBL
  ENSCAFT00000066418.2 UniProtKB/TrEMBL
  ENSCAFT00030025136.1 UniProtKB/TrEMBL
  ENSCAFT00040046793.1 UniProtKB/TrEMBL
  ENSCAFT00040046810.1 UniProtKB/TrEMBL
  ENSCAFT00845004744.1 UniProtKB/TrEMBL
  ENSCAFT00845004756 ENTREZGENE
  ENSCAFT00845004756.1 UniProtKB/TrEMBL
Gene3D-CATH 4.10.900.10 UniProtKB/TrEMBL
  Cadherins UniProtKB/TrEMBL
InterPro Cadherin UniProtKB/TrEMBL
  Cadherin-like_dom UniProtKB/TrEMBL
  Cadherin-like_sf UniProtKB/TrEMBL
  Cadherin_CS UniProtKB/TrEMBL
  Cadherin_cytoplasmic-dom UniProtKB/TrEMBL
  Catenin-bd_sf UniProtKB/TrEMBL
NCBI Gene CDH15 ENTREZGENE
PANTHER CADHERIN-15 UniProtKB/TrEMBL
  PTHR24027 UniProtKB/TrEMBL
Pfam Cadherin UniProtKB/TrEMBL
  Cadherin_C UniProtKB/TrEMBL
PRINTS CADHERIN UniProtKB/TrEMBL
PROSITE CADHERIN_1 UniProtKB/TrEMBL
  CADHERIN_2 UniProtKB/TrEMBL
SMART SM00112 UniProtKB/TrEMBL
Superfamily-SCOP SSF49313 UniProtKB/TrEMBL
UniProt A0A8C0JX43 ENTREZGENE
  A0A8C0NDE2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TV96_CANLF UniProtKB/TrEMBL
  A0A8C0Z6N3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MHE5_CANLF UniProtKB/TrEMBL
  A0A8I3MHF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0SNR7 ENTREZGENE
UniProt Secondary A0A8P0NXI8 UniProtKB/TrEMBL
  A0A8P0SNR7 UniProtKB/TrEMBL
VGNC ID VGNC:39023 ENTREZGENE