LOC480510 (alanyl-tRNA editing protein Aarsd1) - Rat Genome Database

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Gene: LOC480510 (alanyl-tRNA editing protein Aarsd1) Canis lupus familiaris
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Symbol: LOC480510
Name: alanyl-tRNA editing protein Aarsd1
RGD ID: 12149478
Description: ENCODES a protein that exhibits Ser-tRNA(Ala) hydrolase activity (ortholog); INVOLVED IN regulation of translational fidelity (ortholog); FOUND IN cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AARSD1; alanyl-tRNA synthetase domain containing 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,091,116 - 20,102,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,552,733 - 19,563,743 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,809,562 - 20,820,578 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1919,594,654 - 19,605,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,861,356 - 19,872,205 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,963,452 - 19,974,463 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC480510
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1920,091,116 - 20,102,125 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha919,552,733 - 19,563,743 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0920,809,562 - 20,820,578 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1919,594,654 - 19,605,668 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0919,861,356 - 19,872,205 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0919,963,452 - 19,974,463 (+)NCBIUU_Cfam_GSD_1.0
AARSD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381742,950,526 - 42,964,454 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1742,950,526 - 42,964,498 (-)EnsemblGRCh38hg38GRCh38
GRCh371741,102,543 - 41,116,471 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361738,356,069 - 38,385,546 (-)NCBINCBI36Build 36hg18NCBI36
Celera1737,758,676 - 37,788,796 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1736,868,387 - 36,882,289 (-)NCBIHuRef
CHM1_11741,338,174 - 41,352,160 (-)NCBICHM1_1
T2T-CHM13v2.01743,807,669 - 43,821,595 (-)NCBIT2T-CHM13v2.0
Aarsd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911101,297,489 - 101,308,422 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11101,297,665 - 101,308,441 (-)EnsemblGRCm39 Ensembl
GRCm3811101,406,663 - 101,417,508 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11101,406,839 - 101,417,615 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711101,268,153 - 101,278,747 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611101,222,929 - 101,233,523 (-)NCBIMGSCv36mm8
Celera11113,094,285 - 113,104,855 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1164.95NCBI
Aarsd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81086,840,874 - 86,854,077 (-)NCBIGRCr8
mRatBN7.21086,340,625 - 86,353,732 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1086,340,626 - 86,353,729 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1091,377,995 - 91,391,213 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01090,852,888 - 90,865,992 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01086,246,194 - 86,259,298 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01089,317,974 - 89,331,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1089,317,975 - 89,331,078 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01089,115,998 - 89,136,327 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41090,002,331 - 90,015,435 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1085,058,109 - 85,071,213 (-)NCBICelera
Cytogenetic Map10q31NCBI
AARSD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21922,024,338 - 22,040,513 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11723,913,605 - 23,929,784 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01714,358,207 - 14,372,668 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11714,586,286 - 14,600,413 (+)NCBIpanpan1.1PanPan1.1panPan2
LOC101974638
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560219,410,489 - 19,422,843 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493649017,652,296 - 17,664,589 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AARSD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1219,918,248 - 19,926,825 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11219,918,235 - 19,926,828 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in LOC480510
105 total Variants

Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005624433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005624434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022422960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485451 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038485453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038547216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038611182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038676371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_005624433   ⟹   XP_005624490
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,091,116 - 20,102,125 (+)NCBI
Dog10K_Boxer_Tasha919,552,733 - 19,563,743 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005624434   ⟹   XP_005624491
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,091,116 - 20,102,125 (+)NCBI
Dog10K_Boxer_Tasha919,552,733 - 19,563,743 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022422960   ⟹   XP_022278668
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1920,091,116 - 20,099,052 (+)NCBI
Dog10K_Boxer_Tasha919,552,733 - 19,560,653 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038485451   ⟹   XP_038341379
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1919,594,654 - 19,605,668 (+)NCBI
RefSeq Acc Id: XM_038485452   ⟹   XP_038341380
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1919,594,654 - 19,602,578 (+)NCBI
RefSeq Acc Id: XM_038485453   ⟹   XP_038341381
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1919,594,654 - 19,605,668 (+)NCBI
RefSeq Acc Id: XM_038547214   ⟹   XP_038403142
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0919,963,452 - 19,974,463 (+)NCBI
RefSeq Acc Id: XM_038547215   ⟹   XP_038403143
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0919,963,452 - 19,971,373 (+)NCBI
RefSeq Acc Id: XM_038547216   ⟹   XP_038403144
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0919,963,452 - 19,974,463 (+)NCBI
RefSeq Acc Id: XM_038611180   ⟹   XP_038467108
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0919,861,356 - 19,872,205 (+)NCBI
RefSeq Acc Id: XM_038611181   ⟹   XP_038467109
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0919,861,356 - 19,869,116 (+)NCBI
RefSeq Acc Id: XM_038611182   ⟹   XP_038467110
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0919,861,356 - 19,872,205 (+)NCBI
RefSeq Acc Id: XM_038676369   ⟹   XP_038532297
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,809,562 - 20,820,578 (+)NCBI
RefSeq Acc Id: XM_038676370   ⟹   XP_038532298
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,809,562 - 20,817,488 (+)NCBI
RefSeq Acc Id: XM_038676371   ⟹   XP_038532299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0920,809,562 - 20,820,578 (+)NCBI
RefSeq Acc Id: XP_005624491   ⟸   XM_005624434
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005624490   ⟸   XM_005624433
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KGQ8 (UniProtKB/TrEMBL),   A0A8P0SIX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022278668   ⟸   XM_022422960
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_038341379   ⟸   XM_038485451
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038341381   ⟸   XM_038485453
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038341380   ⟸   XM_038485452
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038467108   ⟸   XM_038611180
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038467110   ⟸   XM_038611182
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038467109   ⟸   XM_038611181
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038532297   ⟸   XM_038676369
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KGQ8 (UniProtKB/TrEMBL),   A0A8P0SIX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038532299   ⟸   XM_038676371
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038532298   ⟸   XM_038676370
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038403142   ⟸   XM_038547214
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KGQ8 (UniProtKB/TrEMBL),   A0A8P0SIX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038403144   ⟸   XM_038547216
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038403143   ⟸   XM_038547215
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000045298 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000023254.5 UniProtKB/TrEMBL
Gene3D-CATH 2.40.30.130 UniProtKB/TrEMBL
  Threonyl-trna Synthetase, Chain A, domain 2 UniProtKB/TrEMBL
InterPro Ala-tRNA-synth_IIc_core UniProtKB/TrEMBL
  Alanyl-tRNA_Editing_Enzymes UniProtKB/TrEMBL
  Thr/Ala-tRNA-synth_IIc_edit UniProtKB/TrEMBL
  Transl_B-barrel_sf UniProtKB/TrEMBL
  tRNA_SAD UniProtKB/TrEMBL
NCBI Gene AARSD1 ENTREZGENE
PANTHER ALANYL-TRNA EDITING PROTEIN UniProtKB/TrEMBL
  ALANYL-TRNA EDITING PROTEIN AARSD1 UniProtKB/TrEMBL
Pfam tRNA_SAD UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II_ALA UniProtKB/TrEMBL
SMART tRNA_SAD UniProtKB/TrEMBL
Superfamily-SCOP ThrRS/AlaRS common domain UniProtKB/TrEMBL
  Translation proteins UniProtKB/TrEMBL
UniProt A0A8C0KGQ8 ENTREZGENE
  A0A8P0SIX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC480510  alanyl-tRNA editing protein Aarsd1  AARSD1  alanyl-tRNA synthetase domain containing 1  Symbol and/or name change 5135510 APPROVED