CLIP2 (CAP-Gly domain containing linker protein 2) - Rat Genome Database

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Gene: CLIP2 (CAP-Gly domain containing linker protein 2) Canis lupus familiaris
Analyze
Symbol: CLIP2
Name: CAP-Gly domain containing linker protein 2
RGD ID: 12131532
Description: ENCODES a protein that exhibits microtubule binding (inferred); microtubule plus-end binding (inferred); INVOLVED IN cytoplasmic microtubule organization (inferred); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); intestinal volvulus (ortholog); FOUND IN cytoplasmic microtubule (ortholog); dendritic microtubule (ortholog); lamellar body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CAP-Gly domain-containing linker protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,029,072 - 6,089,974 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,030,793 - 6,081,420 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,729,234 - 7,801,077 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.065,844,725 - 5,916,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl65,844,725 - 5,917,332 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.165,836,600 - 5,908,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,783,859 - 5,855,726 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.065,946,962 - 6,019,151 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CLIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,029,072 - 6,089,974 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl66,030,793 - 6,081,420 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha67,729,234 - 7,801,077 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.065,844,725 - 5,916,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl65,844,725 - 5,917,332 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.165,836,600 - 5,908,332 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.065,783,859 - 5,855,726 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.065,946,962 - 6,019,151 (-)NCBIUU_Cfam_GSD_1.0
CLIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38774,289,407 - 74,405,935 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl774,289,407 - 74,405,935 (+)EnsemblGRCh38hg38GRCh38
GRCh37773,703,737 - 73,820,265 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36773,341,741 - 73,458,209 (+)NCBINCBI36Build 36hg18NCBI36
Build 34773,148,455 - 73,264,915NCBI
Celera769,183,344 - 69,299,516 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef769,585,136 - 69,702,500 (+)NCBIHuRef
CHM1_1773,848,915 - 73,965,381 (+)NCBICHM1_1
T2T-CHM13v2.0775,491,680 - 75,608,201 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2773,036,877 - 73,153,345 (+)NCBI
Clip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395134,518,237 - 134,582,922 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5134,518,237 - 134,581,288 (-)EnsemblGRCm39 Ensembl
GRCm385134,489,383 - 134,553,767 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,489,383 - 134,552,434 (-)EnsemblGRCm38mm10GRCm38
MGSCv375134,965,256 - 135,028,304 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365134,774,013 - 134,837,061 (-)NCBIMGSCv36mm8
Celera5131,497,085 - 131,560,139 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.63NCBI
Clip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81227,798,289 - 27,863,486 (+)NCBIGRCr8
mRatBN7.21222,163,044 - 22,227,023 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1222,163,218 - 22,227,023 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1223,306,274 - 23,370,059 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01223,917,355 - 23,981,144 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01222,983,944 - 23,048,030 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01225,172,957 - 25,236,935 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1225,173,005 - 25,237,009 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01227,173,358 - 27,237,330 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41223,228,309 - 23,292,105 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11223,088,866 - 23,152,661 (+)NCBI
Celera1223,926,969 - 23,990,763 (+)NCBICelera
Cytogenetic Map12q12NCBI
Clip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545613,594,336 - 13,626,012 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545613,593,322 - 13,631,809 (-)NCBIChiLan1.0ChiLan1.0
CLIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2690,494,283 - 90,610,554 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17138,758,915 - 138,875,187 (-)NCBINHGRI_mPanPan1
PanPan1.1781,465,835 - 81,552,522 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl781,465,901 - 81,550,422 (+)Ensemblpanpan1.1panPan2
Clip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344130,660,602 - 130,702,982 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365433,333,677 - 3,372,814 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365433,333,603 - 3,375,965 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1311,419,446 - 11,505,417 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2311,113,365 - 11,159,189 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CLIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,692,837 - 8,792,668 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl288,690,868 - 8,792,555 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660707,796,058 - 7,901,737 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Clip2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474013,675,610 - 13,708,290 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474013,674,727 - 13,716,826 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CLIP2
821 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 11 6 6 12 10 5
Low 5 11 6 6 6 8 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000018930   ⟹   ENSCAFP00000017542
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl66,030,793 - 6,081,420 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000048444   ⟹   ENSCAFP00000039062
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl66,030,793 - 6,081,420 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004315   ⟹   ENSCAFP00845003445
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl65,844,725 - 5,917,332 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845004359   ⟹   ENSCAFP00845003481
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl65,844,725 - 5,917,332 (-)Ensembl
RefSeq Acc Id: XM_038477828   ⟹   XP_038333756
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.165,836,600 - 5,908,332 (-)NCBI
RefSeq Acc Id: XM_038536611   ⟹   XP_038392539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha67,729,234 - 7,801,077 (-)NCBI
RefSeq Acc Id: XM_038536620   ⟹   XP_038392548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha67,729,234 - 7,801,077 (-)NCBI
RefSeq Acc Id: XM_038539074   ⟹   XP_038395002
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.065,946,962 - 6,019,151 (-)NCBI
RefSeq Acc Id: XM_038539075   ⟹   XP_038395003
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.065,946,962 - 6,019,150 (-)NCBI
RefSeq Acc Id: XM_038603166   ⟹   XP_038459094
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.065,783,859 - 5,855,726 (-)NCBI
RefSeq Acc Id: XM_038603167   ⟹   XP_038459095
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.065,783,859 - 5,855,726 (-)NCBI
RefSeq Acc Id: XM_038667872   ⟹   XP_038523800
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.065,844,725 - 5,916,778 (-)NCBI
RefSeq Acc Id: XM_038667873   ⟹   XP_038523801
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.065,844,725 - 5,916,778 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000017542   ⟸   ENSCAFT00000018930
RefSeq Acc Id: ENSCAFP00000039062   ⟸   ENSCAFT00000048444
RefSeq Acc Id: XP_038333756   ⟸   XM_038477828
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038459095   ⟸   XM_038603167
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038459094   ⟸   XM_038603166
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038523801   ⟸   XM_038667873
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KFF9 (UniProtKB/TrEMBL),   A0A8I3MN32 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038523800   ⟸   XM_038667872
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S4H6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392548   ⟸   XM_038536620
- Peptide Label: isoform X2
- UniProtKB: A0A8P0SGN5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038392539   ⟸   XM_038536611
- Peptide Label: isoform X1
- UniProtKB: A0A8P0SGN5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395002   ⟸   XM_038539074
- Peptide Label: isoform X1
- UniProtKB: A0A8C0S4H6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038395003   ⟸   XM_038539075
- Peptide Label: isoform X2
- UniProtKB: A0A8C0KFF9 (UniProtKB/TrEMBL),   A0A8I3MN32 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845003445   ⟸   ENSCAFT00845004315
RefSeq Acc Id: ENSCAFP00845003481   ⟸   ENSCAFT00845004359
Protein Domains
CAP-Gly


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011916 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00040009706 UniProtKB/TrEMBL
  ENSCAFG00845002441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018930.5 UniProtKB/TrEMBL
  ENSCAFT00000048444.4 UniProtKB/TrEMBL
  ENSCAFT00040018031.1 UniProtKB/TrEMBL
  ENSCAFT00845004315 ENTREZGENE
  ENSCAFT00845004315.1 UniProtKB/TrEMBL
  ENSCAFT00845004359 ENTREZGENE
  ENSCAFT00845004359.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.190 UniProtKB/TrEMBL
  6.10.250.1080 UniProtKB/TrEMBL
InterPro CAP-Gly_dom_sf UniProtKB/TrEMBL
  CAP-Gly_domain UniProtKB/TrEMBL
NCBI Gene CLIP2 ENTREZGENE
PANTHER DYNACTIN 1-RELATED MICROTUBULE-BINDING UniProtKB/TrEMBL
  PTHR18916:SF10 UniProtKB/TrEMBL
Pfam CAP_GLY UniProtKB/TrEMBL
PROSITE CAP_GLY_1 UniProtKB/TrEMBL
  CAP_GLY_2 UniProtKB/TrEMBL
SMART CAP_GLY UniProtKB/TrEMBL
Superfamily-SCOP SSF74924 UniProtKB/TrEMBL
UniProt A0A8C0KFF9 ENTREZGENE
  A0A8C0S4H6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MN08_CANLF UniProtKB/TrEMBL
  A0A8I3MN32 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NQQ9_CANLF UniProtKB/TrEMBL
  A0A8P0SGN5 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54013 ENTREZGENE