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Gene: PLA2G4B (phospholipase A2 group IVB) Canis lupus familiaris

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Symbol:

PLA2G4B

Name:

phospholipase A2 group IVB

RGD ID:

12120165

Description:

ENCODES a protein that exhibits lysophospholipase activity (ortholog); phospholipase A1 activity (ortholog); INVOLVED IN phosphatidylcholine acyl-chain remodeling (ortholog); phosphatidylethanolamine acyl-chain remodeling (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; alpha-linolenic acid metabolic pathway; antipyrine drug pathway; ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN early endosome membrane (ortholog); mitochondrial inner membrane (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

cytosolic phospholipase A2 beta; phospholipase A2, group IVB (cytosolic)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	8,865,941 - 8,878,687 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	8,859,257 - 8,876,395 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	8,925,947 - 8,935,469 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	9,001,229 - 9,014,003 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	9,002,061 - 9,014,181 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	8,922,814 - 8,932,335 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	9,026,791 - 9,036,313 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	9,161,786 - 9,171,308 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Neurodevelopmental Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

glycerophospholipid catabolic process (IBA,IEA)

lipid catabolic process (IEA)

phosphatidylcholine acyl-chain remodeling (ISO)

phosphatidylethanolamine acyl-chain remodeling (ISO)

phospholipid catabolic process (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IBA,IEA)

early endosome membrane (ISO)

membrane (IEA)

mitochondrial inner membrane (ISO)

Molecular Function

calcium ion binding (IBA,IEA)

calcium-dependent phospholipase A2 activity (IBA,IEA)

calcium-dependent phospholipid binding (IBA)

hydrolase activity (IEA)

lysophospholipase activity (ISO)

metal ion binding (IEA)

phospholipase A1 activity (ISO)

phospholipase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylsalicylic acid pharmacodynamics pathway (ISO)

alpha-linolenic acid metabolic pathway (ISO)

antipyrine drug pathway (ISO)

arachidonic acid metabolic pathway (ISO)

celecoxib pharmacodynamics pathway (ISO)

diclofenac pharmacodynamics pathway (ISO)

diflunisal pharmacodynamics pathway (ISO)

etodolac pharmacodynamics pathway (ISO)

fenoprofen pharmacodynamics pathway (ISO)

flurbiprofen pharmacodynamics pathway (ISO)

glycerophospholipid metabolic pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

indometacin pharmacodynamics pathway (ISO)

ketoprofen pharmacodynamics pathway (ISO)

ketorolac pharmacodynamics pathway (ISO)

leukotriene C4 synthase deficiency pathway (ISO)

linoleic acid metabolic pathway (ISO)

lornoxicam pharmacodynamics pathway (ISO)

magnesium salicylate pharmacodynamics pathway (ISO)

mefenamic acid pharmacodynamics pathway (ISO)

meloxicam pharmacodynamics pathway (ISO)

nabumetone pharmacodynamics pathway (ISO)

naproxen pharmacodynamics pathway (ISO)

paracetamol drug pathway (ISO)

piroxicam pharmacodynamics pathway (ISO)

salicylic acid pharmacodynamics pathway (ISO)

sodium salicylate pharmacodynamics pathway (ISO)

sulindac pharmacodynamics pathway (ISO)

tenoxicam pharmacodynamics pathway (ISO)

tiaprofenic acid pharmacodynamics pathway (ISO)

tolmetin pharmacodynamics pathway (ISO)

valdecoxib pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

PLA2G4B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	8,865,941 - 8,878,687 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	8,859,257 - 8,876,395 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	8,925,947 - 8,935,469 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	9,001,229 - 9,014,003 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	9,002,061 - 9,014,181 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	8,922,814 - 8,932,335 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	9,026,791 - 9,036,313 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	9,161,786 - 9,171,308 (+)	NCBI		UU_Cfam_GSD_1.0

PLA2G4B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	41,838,847 - 41,848,143 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	41,837,775 - 41,848,147 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	42,131,045 - 42,140,341 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	42,131,011 - 42,140,346 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	15	39,907,605 - 39,927,630	NCBI
Celera	15	18,898,654 - 18,907,988 (+)	NCBI		Celera
Cytogenetic Map	15	q15.1	NCBI
HuRef	15	18,979,399 - 18,988,734 (+)	NCBI		HuRef
CHM1_1	15	42,249,484 - 42,258,819 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	39,644,798 - 39,654,098 (+)	NCBI		T2T-CHM13v2.0

Pla2g4b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	127,458,022 - 127,467,637 (+)	NCBI		GRCr8
mRatBN7.2	3	107,004,238 - 107,013,853 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	107,005,489 - 107,013,853 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	110,680,642 - 110,689,006 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	119,276,197 - 119,284,561 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	116,936,590 - 116,944,954 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	111,824,919 - 111,833,526 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	111,825,162 - 111,834,210 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	118,372,716 - 118,382,163 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	106,540,155 - 106,548,519 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	106,429,577 - 106,444,575 (+)	NCBI
Celera	3	105,914,984 - 105,923,348 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

Pla2g4b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	8,634,184 - 8,642,833 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	8,633,249 - 8,643,219 (+)	NCBI	ChiLan1.0	ChiLan1.0

Pla2g4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	87,296,128 - 87,306,698 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	5,145,502 - 5,153,498 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	5,145,736 - 5,153,930 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLA2G4B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	129,514,346 - 129,524,313 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	129,514,801 - 129,524,365 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	144,556,107 - 144,567,434 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLA2G4B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	41,137,643 - 41,147,384 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	99,854,872 - 99,864,616 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pla2g4b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624804	9,016,487 - 9,026,621 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624804	9,017,154 - 9,026,977 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in PLA2G4B
140 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001204236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014109340	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022412486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038441735	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002621160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005304511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000365	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000030	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000015456 ⟹ ENSCAFP00000014300

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	8,866,785 - 8,876,395 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000015461 ⟹ ENSCAFP00000014305

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	8,859,257 - 8,865,775 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000048065 ⟹ ENSCAFP00000041633

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	30	8,859,328 - 8,876,395 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845053667 ⟹ ENSCAFP00845042168

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	30	9,002,061 - 9,014,181 (+)	Ensembl

RefSeq Acc Id:

NM_001204236 ⟹ NP_001191165

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	30	8,866,785 - 8,876,307 (+)	NCBI
Dog10K_Boxer_Tasha	30	8,925,947 - 8,935,469 (+)	NCBI
ROS_Cfam_1.0	30	9,002,061 - 9,011,583 (+)	NCBI
UMICH_Zoey_3.1	30	8,922,814 - 8,932,335 (+)	NCBI
UNSW_CanFamBas_1.0	30	9,026,791 - 9,036,313 (+)	NCBI
UU_Cfam_GSD_1.0	30	9,161,786 - 9,171,308 (+)	NCBI

Sequence:

show sequence

ATGGCTCTGGCAAAGGTTCCTGGGACCTGCCTGCTCACCGTTCGTGTCCTACAGGCCCATGGCC
TGCCCTCGAAGGACTTAGTGACCCCCTCTGACTGCTACGTAAGCCTTTGGCTGCCCACAGCCTC
TAGCCACAGGCTCCAGACTCGCACAGTCAAGAACTGCAGAAATCCCATCTGGAATCAGAGCTTT
CGCTTTCGAATCCATAGCCAGCTCAAGAATGTCTTACAGCTGCAAGTCTTTGACCAGGACCTTC
TGACCAGTGATGACCCCATGTTGTCAGTGCTGTTTGACGTGGGGACTTTGCAGGCTGGGGAGTT
CCGCCGAGAGAGCTTCTCACTGAACCCTCAGGGCGAGGAGCGGCTAGAAGTTGAATTTCGGCTG
CAGAGACTGACAGACTGTGCCGAGCAGCTTGTCAGCAATGGCATCCTGGTGGCCCGGGAGCTCT
CCTGCTTGCACGTTCGACTGGAGGAGACAGGGAACCAGAAACAGTCAGAGGGCAGAGTTCAACT
TGTGGTTCCTGGGTCCTGTGAGGGTTCACAGGATGCCTCCGTGGGTGCCGGCTCCTTCTGCTTC
CATTGCCCAGCCTGCTGGGAGCAGGAGCTGGGTATTCTTCTGCAGGATGCCCCTCGCGAGCAAC
TGAAGGTGCCCCTCAGGGCCTTGCCCTCTGGCCAAGTGGTGAGGCTTGTCTTCCCTACATCCCA
GGAGCCCCTGATGAGGGTGGAGCTGAGGAAAGAAGAAGGACCGAGGGAGCTGGCCGTGCGTCTA
GGCTGCGGACCGTGTGCCGAGGAGCAGGCCTTCCTGAGCCGGAGGAAGCGGGTGGTGGCCAGAG
CCCTGAAGCAGGTCCTGCAGCTGGGTGAAGACCTGCAGGAGGATGAGATTCCAGTGGTAGCAGT
TATGGCCACTGGCGGTGGGATCCGGGCGATGGTTTCCCTCTATGGACAGCTGGCTGGACTGAGG
GAGCTGGGTCTCTTGGATTGCATCTCCTATATCACAGGGGCCTCAGGCTCCACCTGGGCTTTGG
CCAACCTCTACGAGGACCCGGAATGGTCTCAGAAGGACCTGGCAGGGCCGACCGAGTCACTGAA
GACACAGGTGACCAAGAGCAAGTTGGGTGTACTCTCTCCCAGCCAGCTGCAGCGGTACCACCGG
GAGCTGGGGGAGCGTGCCCGCCTGGGCCACCCGGCCTGCTTCACCAACCTGTGGGCCCTCATCT
GCGAGGCACTGCTGCACGATGAGCCCCATAACCACACACTCTCAGACCAGCGAGAGGCCCTGAG
TCACGGCCAGAACCCTCTGCCCATCTACTGTGCCCTTAACACCAAGGAGAAGAAGCTGAGCACC
TTTGAATTTGGAGAGTGGTGTGAGTTCTCCCCCTATGAGGTTGGCTTTCCCAAGTATGGTGCCT
TCATCCCCTCTGAGCTCTTCGGCTCTGAGTTCTTCATGGGGCGCCTGACCAAGCGGCTTCCTGA
GTCCCGAATCTGCTTCCTCGAAGGTATCTGGAGCAACCTATATGCAGCCAACCTCCAGGATAGT
TTATACTGGGCCTCAGACCCCAGTCAGTTCTGGGACCGCTGGGCACAGGATCAGGCCAACCTGG
ACAAGGAGCAGGTCCCTCTTCTAAAGATAGAAGAGCCTCCCACTGGGACTGGCAGGATTGTTGA
GTTTTTCACTGACCTTCTGACGCGGCGCCCACTGGCCCAGGCCACCCACAATTTCCTGCATGGC
CTCCATTTCCACAAGGACTACTTCCAACATCCTTACTTCTCTACCTGGAAAGCCACCAAACTGG
ATGGGCTCCCCAACCAGCTGACACCTGCAGAGCCCCACCTTTGCCTGCTGGATGTTGGCTACCT
TATCAACACCAGCTTCCCGCCCCTACTGCGGCCCACACGGGACGTGGACCTCATCCTGTCGCTG
GATTACAACCTCCAAGGAGCCTTTCAGCAACTGCAGCTCCTGGGCCGGTGGTGCCAGGAGCAGG
GCATCCCGTTCCCACCCATCTCACCCAGCGTTGGAGAGCAGCAGCAGCCAGGAGAGTGCCACTC
GTTTTTGGACCCAGACTGCCCCGAGGCCCCAGCTGTGCTGCACTTCCCTCTAGTGGATGACTCC
TTCCAGGAGTACTCGGCCCCTGGCATCCGGCGCACACCAGAGGAAAAGGCGGCGGGGGAGGTGA
ACCTATCTTCCTCCGACTCCCCCTACCACTACTCCAAGGTGACCTACAGCCCAGAGGACATGGA
CAAGCTGCTGCGCCTGACCCACTACAACATCTGCAACAACCGGGAGCAGCTGCTAGAGGCCCTG
CGTGCGGCTGTGCAGCGGAGGCGGGAGCGCAGGCAGCGCCACCCCCAGTGA

hide sequence

RefSeq Acc Id:

XM_038441735 ⟹ XP_038297663

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	9,003,981 - 9,014,003 (+)	NCBI

RefSeq Acc Id:

XR_005304511

Type:

NON-CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	30	9,001,229 - 9,014,003 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001191165	(Get FASTA)	NCBI Sequence Viewer
	XP_038297663	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000014300.3
	ENSCAFP00030034882.1
	ENSCAFP00040018637.1
	ENSCAFP00845042168
	ENSCAFP00845042168.1

RefSeq Acc Id:

NP_001191165 ⟸ NM_001204236

- UniProtKB:

A0A8C0YVX1 (UniProtKB/TrEMBL), A0A8I3QXI0 (UniProtKB/TrEMBL), A0A8P0SER8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MALAKVPGTCLLTVRVLQAHGLPSKDLVTPSDCYVSLWLPTASSHRLQTRTVKNCRNPIWNQSF
RFRIHSQLKNVLQLQVFDQDLLTSDDPMLSVLFDVGTLQAGEFRRESFSLNPQGEERLEVEFRL
QRLTDCAEQLVSNGILVARELSCLHVRLEETGNQKQSEGRVQLVVPGSCEGSQDASVGAGSFCF
HCPACWEQELGILLQDAPREQLKVPLRALPSGQVVRLVFPTSQEPLMRVELRKEEGPRELAVRL
GCGPCAEEQAFLSRRKRVVARALKQVLQLGEDLQEDEIPVVAVMATGGGIRAMVSLYGQLAGLR
ELGLLDCISYITGASGSTWALANLYEDPEWSQKDLAGPTESLKTQVTKSKLGVLSPSQLQRYHR
ELGERARLGHPACFTNLWALICEALLHDEPHNHTLSDQREALSHGQNPLPIYCALNTKEKKLST
FEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGRLTKRLPESRICFLEGIWSNLYAANLQDS
LYWASDPSQFWDRWAQDQANLDKEQVPLLKIEEPPTGTGRIVEFFTDLLTRRPLAQATHNFLHG
LHFHKDYFQHPYFSTWKATKLDGLPNQLTPAEPHLCLLDVGYLINTSFPPLLRPTRDVDLILSL
DYNLQGAFQQLQLLGRWCQEQGIPFPPISPSVGEQQQPGECHSFLDPDCPEAPAVLHFPLVDDS
FQEYSAPGIRRTPEEKAAGEVNLSSSDSPYHYSKVTYSPEDMDKLLRLTHYNICNNREQLLEAL
RAAVQRRRERRQRHPQ

hide sequence

Ensembl Acc Id:

ENSCAFP00000014300 ⟸ ENSCAFT00000015456

Ensembl Acc Id:

ENSCAFP00000014305 ⟸ ENSCAFT00000015461

Ensembl Acc Id:

ENSCAFP00000041633 ⟸ ENSCAFT00000048065

RefSeq Acc Id:	XP_038297663 ⟸ XM_038441735
- Peptide Label:	isoform X1
- UniProtKB:	A0A8P0SER8 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845042168 ⟸ ENSCAFT00845053667

Protein Domains

C2 PLA2c

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000009735	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030021714	UniProtKB/TrEMBL
	ENSCAFG00040011523	UniProtKB/TrEMBL
	ENSCAFG00845030242	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000015456.6	UniProtKB/TrEMBL
	ENSCAFT00030039980.1	UniProtKB/TrEMBL
	ENSCAFT00040021466.1	UniProtKB/TrEMBL
	ENSCAFT00845053667	ENTREZGENE
	ENSCAFT00845053667.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.150	UniProtKB/TrEMBL
	Cytosolic phospholipase A2 catalytic domain	UniProtKB/TrEMBL
InterPro	Acyl_Trfase/lysoPLipase	UniProtKB/TrEMBL
	C2_cPLA2	UniProtKB/TrEMBL
	C2_dom	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	cPLA2_C2	UniProtKB/TrEMBL
	LysoPLipase_cat_dom	UniProtKB/TrEMBL
KEGG Report	cfa:487512	UniProtKB/TrEMBL
NCBI Gene	PLA2G4B	ENTREZGENE
PANTHER	CYTOSOLIC PHOSPHOLIPASE A2	UniProtKB/TrEMBL
	CYTOSOLIC PHOSPHOLIPASE A2 BETA	UniProtKB/TrEMBL
Pfam	cPLA2_C2	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
	PLA2_B	UniProtKB/TrEMBL
PROSITE	PLA2C	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
SMART	PLAc	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/TrEMBL
	SSF52151	UniProtKB/TrEMBL
UniProt	A0A8C0RQL2_CANLF	UniProtKB/TrEMBL
	A0A8C0YVX1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3QXI0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0SER8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-15	PLA2G4B	phospholipase A2 group IVB	PLA2G4B	phospholipase A2, group IVB (cytosolic)	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Annotations - SMPDB