CHMP3 (charged multivesicular body protein 3) - Rat Genome Database

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Gene: CHMP3 (charged multivesicular body protein 3) Canis lupus familiaris
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Symbol: CHMP3
Name: charged multivesicular body protein 3
RGD ID: 12102629
Description: ENCODES a protein that exhibits identical protein binding (ortholog); molecular function inhibitor activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN endosome to lysosome transport (ortholog); mitotic metaphase chromosome alignment (ortholog); nucleus organization (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH CD8 Deficiency, Familial (ortholog); FOUND IN amphisome membrane (ortholog); autophagosome membrane (ortholog); early endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: vacuolar protein sorting 24 homolog; VPS24
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,600,793 - 38,658,368 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,286,558 - 38,344,133 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,333,768 - 39,391,356 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,332,859 - 39,393,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,499,831 - 38,557,408 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,536,249 - 38,593,804 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,884,203 - 38,941,802 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
CHMP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11738,600,793 - 38,658,368 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1738,286,558 - 38,344,133 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01739,333,768 - 39,391,356 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1739,332,859 - 39,393,172 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11738,499,831 - 38,557,408 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01738,536,249 - 38,593,804 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01738,884,203 - 38,941,802 (+)NCBIUU_Cfam_GSD_1.0
CHMP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38286,503,430 - 86,563,443 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl286,503,430 - 86,563,479 (-)EnsemblGRCh38hg38GRCh38
GRCh37286,730,553 - 86,790,566 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36286,584,064 - 86,644,111 (-)NCBINCBI36Build 36hg18NCBI36
Build 34286,642,210 - 86,702,258NCBI
Celera286,558,596 - 86,618,513 (-)NCBICelera
Cytogenetic Map2p11.2NCBI
HuRef286,628,305 - 86,688,178 (-)NCBIHuRef
CHM1_1286,660,612 - 86,720,561 (-)NCBICHM1_1
T2T-CHM13v2.0286,505,444 - 86,565,457 (-)NCBIT2T-CHM13v2.0
Chmp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39671,520,820 - 71,559,593 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl671,520,781 - 71,559,593 (+)EnsemblGRCm39 Ensembl
GRCm38671,543,831 - 71,582,609 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl671,543,797 - 71,582,609 (+)EnsemblGRCm38mm10GRCm38
MGSCv37671,493,848 - 71,531,568 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36671,473,363 - 71,511,083 (+)NCBIMGSCv36mm8
Celera673,623,309 - 73,665,394 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map632.17NCBI
Chmp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84105,134,860 - 105,180,862 (+)NCBIGRCr8
mRatBN7.24103,576,453 - 103,622,566 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4103,576,515 - 103,623,959 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4108,959,774 - 109,006,553 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04104,734,897 - 104,781,676 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04103,346,475 - 103,392,244 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0499,449,213 - 99,496,156 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl499,449,111 - 99,494,423 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04164,228,516 - 164,275,602 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44104,812,177 - 104,857,896 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14105,056,657 - 105,102,377 (+)NCBI
Celera492,735,412 - 92,780,550 (+)NCBICelera
Cytogenetic Map4q32NCBI
CHMP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21239,816,276 - 39,876,240 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A39,819,055 - 39,879,001 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A86,559,695 - 86,619,615 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A88,105,216 - 88,224,003 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A88,106,242 - 88,165,104 (-)Ensemblpanpan1.1panPan2
Chmp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629279,813,720 - 79,834,454 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367121,023,989 - 1,044,728 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367121,023,994 - 1,044,727 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHMP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl358,206,921 - 58,279,248 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1358,206,921 - 58,279,252 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2360,964,960 - 61,037,189 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHMP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11420,536,490 - 20,654,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1420,594,817 - 20,654,404 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604591,842,572 - 91,903,310 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chmp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474916,738,416 - 16,772,391 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474916,738,538 - 16,772,553 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CHMP3
573 total Variants

Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCAFT00845023453   ⟹   ENSCAFP00845018407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1739,332,859 - 39,393,172 (+)Ensembl
RefSeq Acc Id: XM_014120401   ⟹   XP_013975876
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11738,600,793 - 38,658,349 (+)NCBI
Dog10K_Boxer_Tasha1738,286,558 - 38,344,133 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022404740   ⟹   XP_022260448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11738,600,809 - 38,658,368 (+)NCBI
Dog10K_Boxer_Tasha1738,286,576 - 38,344,122 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038498942   ⟹   XP_038354870
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11738,499,831 - 38,557,408 (+)NCBI
RefSeq Acc Id: XM_038498943   ⟹   XP_038354871
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11738,499,849 - 38,557,397 (+)NCBI
RefSeq Acc Id: XM_038561528   ⟹   XP_038417456
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01738,884,203 - 38,941,802 (+)NCBI
RefSeq Acc Id: XM_038561529   ⟹   XP_038417457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01738,884,221 - 38,941,791 (+)NCBI
RefSeq Acc Id: XM_038625571   ⟹   XP_038481499
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01738,536,249 - 38,593,804 (+)NCBI
RefSeq Acc Id: XM_038625572   ⟹   XP_038481500
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01738,536,267 - 38,593,793 (+)NCBI
RefSeq Acc Id: XM_038691492   ⟹   XP_038547420
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01739,333,768 - 39,391,356 (+)NCBI
RefSeq Acc Id: XM_038691493   ⟹   XP_038547421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01739,333,786 - 39,391,345 (+)NCBI
RefSeq Acc Id: XP_013975876   ⟸   XM_014120401
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_022260448   ⟸   XM_022404740
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_038354870   ⟸   XM_038498942
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038354871   ⟸   XM_038498943
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038481499   ⟸   XM_038625571
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038481500   ⟸   XM_038625572
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038547420   ⟸   XM_038691492
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038547421   ⟸   XM_038691493
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038417456   ⟸   XM_038561528
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038417457   ⟸   XM_038561529
- Peptide Label: isoform X2
Ensembl Acc Id: ENSCAFP00845018407   ⟸   ENSCAFT00845023453


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007479 UniProtKB/TrEMBL
  ENSCAFG00030007213 UniProtKB/TrEMBL
  ENSCAFG00040015946 UniProtKB/TrEMBL
  ENSCAFG00845013177 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000061039.2 UniProtKB/TrEMBL
  ENSCAFT00000094138.1 UniProtKB/TrEMBL
  ENSCAFT00030013310.1 UniProtKB/TrEMBL
  ENSCAFT00030013415.1 UniProtKB/TrEMBL
  ENSCAFT00040029377.1 UniProtKB/TrEMBL
  ENSCAFT00040029433.1 UniProtKB/TrEMBL
  ENSCAFT00845023453.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1230 UniProtKB/TrEMBL
InterPro Snf7_fam UniProtKB/TrEMBL
NCBI Gene CHMP3 ENTREZGENE
PANTHER CHARGED MULTIVESICULAR BODY PROTEIN 3 UniProtKB/TrEMBL
  PTHR10476 UniProtKB/TrEMBL
Pfam Snf7 UniProtKB/TrEMBL
UniProt A0A8C0MQ70_CANLF UniProtKB/TrEMBL
  A0A8C0SRE9_CANLF UniProtKB/TrEMBL
  A0A8I3NDI3_CANLF UniProtKB/TrEMBL
UniProt Secondary A0A8P0T1J5 UniProtKB/TrEMBL