MEX3D (mex-3 RNA binding family member D) - Rat Genome Database

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Gene: MEX3D (mex-3 RNA binding family member D) Canis lupus familiaris
Analyze
Symbol: MEX3D
Name: mex-3 RNA binding family member D
RGD ID: 12081252
Description: ENCODES a protein that exhibits mRNA 3'-UTR AU-rich region binding (ortholog); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); cyclic hematopoiesis (ortholog); genetic disease (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: mex-3 homolog D; ring finger and KH domain containing 1; RKHD1; RNA-binding protein MEX3D
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,317,232 - 57,323,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,108,106 - 57,115,122 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,046,899 - 58,053,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,046,120 - 58,053,832 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,103,940 - 57,110,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,582,417 - 57,589,935 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,784,813 - 57,791,846 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MEX3D
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,317,232 - 57,323,854 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,108,106 - 57,115,122 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,046,899 - 58,053,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,046,120 - 58,053,832 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,103,940 - 57,110,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,582,417 - 57,589,935 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02057,784,813 - 57,791,846 (+)NCBIUU_Cfam_GSD_1.0
MEX3D
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,554,672 - 1,568,325 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,554,672 - 1,568,325 (-)EnsemblGRCh38hg38GRCh38
GRCh37191,554,671 - 1,568,324 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,505,668 - 1,519,057 (-)NCBINCBI36Build 36hg18NCBI36
Build 34191,505,671 - 1,518,529NCBI
Celera191,489,519 - 1,502,909 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef191,328,987 - 1,331,058 (-)NCBIHuRef
CHM1_1191,554,945 - 1,568,173 (-)NCBICHM1_1
T2T-CHM13v2.0191,525,487 - 1,539,144 (-)NCBIT2T-CHM13v2.0
Mex3d
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391080,216,189 - 80,223,485 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1080,216,189 - 80,223,493 (-)EnsemblGRCm39 Ensembl
GRCm381080,380,355 - 80,387,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1080,380,355 - 80,387,659 (-)EnsemblGRCm38mm10GRCm38
MGSCv371079,843,100 - 79,850,396 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,783,609 - 79,789,956 (-)NCBIMGSCv36mm8
Celera1081,397,612 - 81,404,722 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Mex3d
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr879,976,253 - 9,983,383 (+)NCBIGRCr8
mRatBN7.279,325,575 - 9,332,705 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,325,488 - 9,332,096 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,202,049 - 12,209,187 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,077,389 - 14,084,527 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0711,945,080 - 11,952,218 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,191,902 - 12,198,841 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,192,088 - 12,198,551 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,361,694 - 12,368,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4710,832,697 - 10,844,164 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1710,831,500 - 10,844,164 (+)NCBI
Celera77,503,888 - 7,510,589 (+)NCBICelera
Cytogenetic Map7q11NCBI
Mex3d
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554956,394,784 - 6,401,963 (+)NCBIChiLan1.0ChiLan1.0
MEX3D
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,919,416 - 5,933,088 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1195,150,267 - 5,163,966 (-)NCBINHGRI_mPanPan1
PanPan1.1191,526,190 - 1,530,465 (-)NCBIpanpan1.1PanPan1.1panPan2
Mex3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118216,976,465 - 216,984,178 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588850,904 - 858,322 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588850,049 - 858,318 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEX3D
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl276,929,619 - 76,938,367 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1276,929,583 - 76,938,238 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2278,141,931 - 78,150,376 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEX3D
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.161,315,113 - 1,347,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236664417 - 14,100 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mex3d
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,146,823 - 7,157,745 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,149,766 - 7,157,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MEX3D
101 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00845025532   ⟹   ENSCAFP00845020101
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2058,046,120 - 58,053,832 (+)Ensembl
RefSeq Acc Id: XM_038426675   ⟹   XP_038282603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02058,046,899 - 58,053,937 (+)NCBI
RefSeq Acc Id: XM_038455345   ⟹   XP_038311273
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2057,108,106 - 57,115,122 (+)NCBI
RefSeq Acc Id: XM_038504982   ⟹   XP_038360910
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12057,103,940 - 57,110,670 (+)NCBI
RefSeq Acc Id: XM_038565392   ⟹   XP_038421320
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02057,784,813 - 57,791,846 (+)NCBI
RefSeq Acc Id: XM_038629511   ⟹   XP_038485439
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02057,582,417 - 57,589,935 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038360910   ⟸   XM_038504982
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038485439   ⟸   XM_038629511
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038282603   ⟸   XM_038426675
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q5N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038311273   ⟸   XM_038455345
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q5N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038421320   ⟸   XM_038565392
- Peptide Label: isoform X4
- UniProtKB: A0A8C0Q5N1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845020101   ⟸   ENSCAFT00845025532
Protein Domains
RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00040005712 UniProtKB/TrEMBL
  ENSCAFG00845014280 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00040010700.1 UniProtKB/TrEMBL
  ENSCAFT00845025532.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1370.10 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro KH-I_MEX3_rpt1 UniProtKB/TrEMBL
  KH-I_MEX3_rpt2 UniProtKB/TrEMBL
  KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  MEX3 UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene MEX3D ENTREZGENE
PANTHER RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 UniProtKB/TrEMBL
  RNA-BINDING PROTEIN MEX3D UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/TrEMBL
  zf-C3HC4_3 UniProtKB/TrEMBL
PROSITE KH_TYPE_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART SM00322 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54791 UniProtKB/TrEMBL
UniProt A0A8C0Q5N1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NQ44_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:81279 ENTREZGENE