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Gene: CAPN6 (calpain 6) Canis lupus familiaris

Analyze

Symbol:

CAPN6

Name:

calpain 6

RGD ID:

12070852

Description:

ENCODES a protein that exhibits calcium-dependent cysteine-type endopeptidase activity (inferred); microtubule binding (inferred); INVOLVED IN microtubule bundle formation (inferred); proteolysis (inferred); regulation of cytoskeleton organization (inferred); ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); developmental and epileptic encephalopathy 36 (ortholog); FOUND IN microtubule (inferred); perinuclear region of cytoplasm (inferred); spindle microtubule (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

calpain-6

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CAPN6 (calpain 6)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Capn6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Capn6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Capn6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CAPN6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Capn6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CAPN6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CAPN6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Capn6 (calpain 6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	84,351,483 - 84,377,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	84,351,480 - 84,378,183 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	70,452,893 - 70,478,661 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	86,013,239 - 86,039,076 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	86,013,232 - 86,039,110 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	83,496,162 - 83,521,922 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	85,173,775 - 85,199,625 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	85,002,271 - 85,028,105 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

autosomal hemophilia A (ISO)

developmental and epileptic encephalopathy 36 (ISO)

factor VIII deficiency (ISO)

hypertension (ISO)

prostate cancer (ISO)

schizophrenia (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule bundle formation (IEA)

proteolysis (IBA,IEA)

regulation of cytoskeleton organization (IEA)

Cellular Component

cytoplasm (IBA)

microtubule (IEA)

perinuclear region of cytoplasm (IEA)

spindle microtubule (IEA)

Molecular Function

calcium-dependent cysteine-type endopeptidase activity (IBA,IEA)

microtubule binding (IEA)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CAPN6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	84,351,483 - 84,377,365 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	84,351,480 - 84,378,183 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	70,452,893 - 70,478,661 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	86,013,239 - 86,039,076 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	86,013,232 - 86,039,110 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	83,496,162 - 83,521,922 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	85,173,775 - 85,199,625 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	85,002,271 - 85,028,105 (-)	NCBI		UU_Cfam_GSD_1.0

CAPN6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	111,245,099 - 111,270,483 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	111,245,099 - 111,270,483 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	110,488,327 - 110,513,711 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	110,374,987 - 110,400,407 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	110,294,475 - 110,319,896	NCBI
Celera	X	110,967,943 - 110,993,390 (-)	NCBI		Celera
Cytogenetic Map	X	q23	NCBI
HuRef	X	100,110,837 - 100,136,321 (-)	NCBI		HuRef
CHM1_1	X	110,399,827 - 110,425,289 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	109,693,306 - 109,718,689 (-)	NCBI		T2T-CHM13v2.0

Capn6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	142,585,232 - 142,610,408 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	142,585,227 - 142,610,410 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	143,802,236 - 143,827,412 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	143,802,231 - 143,827,414 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	140,236,779 - 140,261,955 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	139,048,604 - 139,073,663 (-)	NCBI		MGSCv36	mm8
Celera	X	127,758,391 - 127,783,584 (-)	NCBI		Celera
Cytogenetic Map	X	F2	NCBI
cM Map	X	64.83	NCBI

Capn6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	112,177,467 - 112,202,178 (-)	NCBI		GRCr8
mRatBN7.2	X	107,380,774 - 107,405,489 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	107,380,774 - 107,405,489 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	109,518,601 - 109,543,298 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	113,018,304 - 113,043,001 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	110,571,881 - 110,596,588 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	115,049,113 - 115,073,824 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	115,049,154 - 115,073,890 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	113,502,312 - 113,527,023 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	34,697,658 - 34,722,369 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	34,751,126 - 34,775,838 (+)	NCBI
Celera	X	106,779,922 - 106,804,635 (-)	NCBI		Celera
Cytogenetic Map	X	q33	NCBI

Capn6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955490	4,499,882 - 4,526,060 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955490	4,499,888 - 4,526,060 (+)	NCBI	ChiLan1.0	ChiLan1.0

CAPN6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	110,738,095 - 110,763,471 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	110,741,706 - 110,767,064 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	100,363,233 - 100,388,631 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	110,822,550 - 110,847,955 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	110,822,170 - 110,848,000 (-)	Ensembl	panpan1.1		panPan2

Capn6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	83,597,063 - 83,622,272 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936499	4,035,664 - 4,060,895 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936499	4,041,837 - 4,060,895 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAPN6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	91,258,688 - 91,288,077 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	91,258,696 - 91,288,128 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	105,673,303 - 105,702,721 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAPN6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	99,052,100 - 99,077,508 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	99,051,989 - 99,077,302 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	24,290,975 - 24,316,307 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Capn6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624803	4,339,368 - 4,373,298 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624803	4,339,368 - 4,373,400 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in CAPN6
202 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
3	5	2	22	20	13	5	1	5	6	23	13	12	14	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_022416026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022416027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038450652	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038524116	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038588092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038652608	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_549188	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000146	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000394	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000110	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000175	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000028872 ⟹ ENSCAFP00000026850

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	84,351,480 - 84,378,183 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000091991 ⟹ ENSCAFP00000053676

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	X	84,351,480 - 84,378,183 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845039430 ⟹ ENSCAFP00845030899

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	X	86,013,232 - 86,039,110 (-)	Ensembl

RefSeq Acc Id:

XM_038450652 ⟹ XP_038306580

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	X	86,013,239 - 86,039,076 (-)	NCBI

RefSeq Acc Id:

XM_038524116 ⟹ XP_038380044

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	X	83,496,162 - 83,521,922 (-)	NCBI

RefSeq Acc Id:

XM_038588092 ⟹ XP_038444020

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	X	85,002,271 - 85,028,105 (-)	NCBI

RefSeq Acc Id:

XM_038652608 ⟹ XP_038508536

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	X	85,173,775 - 85,199,625 (-)	NCBI

RefSeq Acc Id:

XM_549188 ⟹ XP_549188

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	X	84,351,483 - 84,377,364 (-)	NCBI
Dog10K_Boxer_Tasha	X	70,452,893 - 70,478,661 (-)	NCBI

Sequence:

show sequence

TGAGCAGAGCATGGTACAGCCCAAATAGTTTTCAGGTTAAGAAAGCCTGAATCTTTGTTCAGCC
ACACTCACTGAACAGACTTTGTAGGGGTTACCTGGTTAAGAGTGGCAGCGGCGGCAGCTGCAGC
AAGGCTCCTGGGATAACTCAGTTTGGCACTATGGGTCCTCCTCTGAAGCTCTTCAAAAACCAGA
AGTACCAGGAACTGAAGCAGGAATGCATCAAAGATGGCAGACTTTTCTGTGACCCAACTTTTCT
GCCTGAGAATGATTCACTTTTCTATAACCGACTGCTTCCCGGGAAGGTGGTGTGGAAACGTCCC
CAGGACATCTGTGATGACCCCCACCTGATCGTGGGCAACATCAGCAACCACCAGCTGATCCAAG
GGAGACTGGGGCACAAGCCAATGGTCTCTGCATTTTCCTGTTTGGCTGTTCAGGAGTCTCACTG
GACAAAGACAATTCCCAACCATAAGGAACAGGAATGGGACCCTCGAAAACTCGATAAATATGCT
GGGATATTTCGCTTCCGTTTCTGGCATTTTGGAGAATGGACTGAGGTAGTGATTGATGATTTGC
TGCCCACCATCAATGGAGATCTGGTTTTCTCCTTCTCCACCTCCATGAATGAGTTTTGGAATGC
TCTACTGGAAAAAGCTTATGCAAAACTGCTGGGTTGTTATGAAGCCCTCGATGGTTTGACCACC
ACTGATATCATTGTGGACTTCACTGGCACATTGGCCGAAACCATTGACATGCAGAAGGGAAGAT
ACACCGAGCTGGTTGAGGAGAAGTACAAGCTGTTCGGGGAGCTATACAAAACATTTACCAAAGG
AGGACTGATCTGTTGCTCCATTGAGTCTCCCAATCAGGAGGAACAAGAAGTGGAAACTGACTGG
GGTCTTCTGAAGGGCCATACTTACACCTTGACTGATATTCGCAAGATCCGTCTTGGAGAAAGAT
TGCTGGAAGTCTTCAGTACTGAGAAGCTCTACATGGTTCGCCTGAGGAACCCCTTAGGACGACA
GGAATGGAGCGGCCCCTGGAGCGAAATTTCTGAGGAGTGGCAGCAGCTGACTGTGGCAGACCGC
AAAAACCTGGGGCTTGTTATGTCTGATGATGGAGAGTTCTGGATGAGCCTGGAGGACTTTTGCC
GCAACTTTCATGAACTGAATGTCTGCCGCAATGTGAACAACCCTATCTTTGGCCGCAAGGAGCT
GGAATCGGTGGTGGGATGCTGGACAGTGGATGATGATCCCCTGATGAACCGGTCGGGAGGCTGC
TATAACAATCGTGATACCTTCCTGCAGAATCCGCAGTACATCTTCACTGTGCCTGAGGATGGGC
ACAAGGTCATTATGTCACTGCAGCAAAAGGACCTGCGTACTTACCGGCGCATGGGAAGACCTGA
CAATTACATCATTGGATTTGAGCTCTTCAAGGTGGAGATGAACCGCAGATTCCGCCTCCACCAT
CTCTACATCCAGGAGCGTGCAGGGACTTCCACCTATATTGACACTCGCACCGTGTTTCTGAGCA
AGTACCTGAAGAAAGGCAACTACGTGCTTGTCCCGACCATGTTCCAGCATGGCCGCACCAGCGA
GTTTCTCCTGAGGATCTTCTCTGAAGTGCCCGTCCAGCTCAGGGAACTGACTCTGGACATGCCT
AAGATGTCCTGCTGGAACCTGGCTCGTGGCTACCCGAAAGTAGTCACCCAGATAACTGTTCACA
GCGCTGAGGGCCTGGAAAAGAAATATGCCAATGAAACGGTAAATCCATATTTGGTCATCAAGTG
TGGAAAGGAGGAAGTCCGTTCTCCTGTCCAAAAGAATACTGTTCATGCCATTTTTGACACCCAG
GCAATTTTCTACAGAAGGACCACTGACATTCCTATTATAGTGCAGGTGTGGAACAGCCGAAAAT
TCTGTGATCAATTCCTGGGGCAGGTGACTCTGGATGCTGACCCCAGCGACTGCCGTGATCTGAA
GTCTCTGTACCTGCGCAAGAAGGGTGGCCCAACTGCCAAAGTCAAGCAGGGCCACATCAGCTTC
AAGGTTATTTCCAGCGATGATCTCACTGAGCTCTAAATCTCCAGCTCTAAGGAGTCCTGACAGA
GCTTTCCATCCTTTATATTTTCTGTCAGATGCCAGGTCTTACCTAATTCATAATCTTTTGAAAG
AAAGAAACTCACAGTAACTCACTTTTCCTTTCTTCTGAGAAATTCCCCATACCTCCCGATCCAA
GTAGCATCAGTAGCTACATAACCTATATACCTCCAGCAGCTGGACAGGGGCAGGTGACAGTCCT
ATGTGGAGATCATACAGATGTTTGCCATCCAAAGATCGCTGGGGCTTCCGGGGGTGAGATTTCA
GCAGGACAACAACAGCATGGATACCCTACAGATGTCTTTGCTGCTTTCAGGTGCCCAGTGTTAT
CTCTCCTGTAGGGCATGTTAAGGAAGGAGGAGGGGTGATCAAGGCCAAGCTGGTCTAGCCTGAC
ATCCCAGCTCCTGACTTAATACTACAGACTTCCCAGCAGCATTTTCACCAGCAGCTAGAGCCTG
CTTCTAAGTCCCCAGCCTTTATCACCACCAACACCAGTGCCACCTCCAACCACCACCACTGATC
ACCACCACCATCACCACCTCCGGAAAGTGTAGTCCTGCCCTAACCCAAGTCACCCCCCACAGTA
GGTTTCACCTTCATGTTGAGGAAGCTTCCTAGGTGCTTAATGACGAGCTGAGAGTTCAGTGAGG
CCTAGACAGCAAGCAGGGCCTGAGCTCCAGCTCTGTGGAAGCCAGCTGTGTGCCGCAAGAGGGA
AAAGTGGAAGAAGCTGCAGTGGGAGACAAAGCCTCGGTCCCCCACCCATCCACACACACCTACA
CTCACACACGCGCACATGGGCGCGCATGAACTATGGTTCAGGCAGTCAGTGGGCAAGAGGAAGG
ATGAATCAGTACCACACCCCCCCCGAAAAGATGAGAAAAATCCACCCAGGCGTAGTCTAGCCAG
TTTGGGGCCCCTGACTGCAATGTGAAATCTCCTGCTGCTGCTAGGTTTACAAACAAGCCCATTG
TCCTGTGCCTCCTAATATCATTGGTACTGAAGCCCCATTTGGGGGCTTGAGATTTTGGGTCCCA
GCCCCGGGCCCCTCAGCTTTTGCTCCGAGTTGGGTAGCTTCACTCCCTGGGGGCGTTTGTTTGC
CCTCTTGTGTTTTCAGTATTTCTACAGAATTTCTCTAGAGTCAGTCATTCTAGAATGTTCTTCC
CTCCATCTCATCTATCAACAGTCTACCCCTCCTTCAAGGTCCAGCATAAATGCCACCTCCTCCA
TGAAGCCTTCCCTAACCCCTCCCAACCCCCCACCTCTGACAGTTATTTCAATGCTTCTGCAATG
ATGAAGATAAAACATAGTTGTAGTACTTAGTCTAGTCCAGCACGCATTCATTTACAAATATATT
TTGTAGGTTTTTTTTTTTTTAGCTCACTCATTTCCTACCATGTTTTTCAGTCTGTGTAACTTCT
GCAGTGCCTTCACCACACTGCCTTACATAATCCAAACCACAATAAAGTTCACATTCAATAAAGC
GA

hide sequence

Protein Sequences


Protein RefSeqs	XP_038306580	(Get FASTA)	NCBI Sequence Viewer
	XP_038380044	(Get FASTA)	NCBI Sequence Viewer
	XP_038444020	(Get FASTA)	NCBI Sequence Viewer
	XP_038508536	(Get FASTA)	NCBI Sequence Viewer
	XP_549188	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000026850.3
	ENSCAFP00030033646.1
	ENSCAFP00040023998.1
	ENSCAFP00845030899
	ENSCAFP00845030899.1

RefSeq Acc Id:

XP_549188 ⟸ XM_549188

- UniProtKB:

A0A8C0SR05 (UniProtKB/TrEMBL), A0A8C0QVM2 (UniProtKB/TrEMBL), A0A8I3PJW4 (UniProtKB/TrEMBL), A0A8C0JW52 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGPPLKLFKNQKYQELKQECIKDGRLFCDPTFLPENDSLFYNRLLPGKVVWKRPQDICDDPHLI
VGNISNHQLIQGRLGHKPMVSAFSCLAVQESHWTKTIPNHKEQEWDPRKLDKYAGIFRFRFWHF
GEWTEVVIDDLLPTINGDLVFSFSTSMNEFWNALLEKAYAKLLGCYEALDGLTTTDIIVDFTGT
LAETIDMQKGRYTELVEEKYKLFGELYKTFTKGGLICCSIESPNQEEQEVETDWGLLKGHTYTL
TDIRKIRLGERLLEVFSTEKLYMVRLRNPLGRQEWSGPWSEISEEWQQLTVADRKNLGLVMSDD
GEFWMSLEDFCRNFHELNVCRNVNNPIFGRKELESVVGCWTVDDDPLMNRSGGCYNNRDTFLQN
PQYIFTVPEDGHKVIMSLQQKDLRTYRRMGRPDNYIIGFELFKVEMNRRFRLHHLYIQERAGTS
TYIDTRTVFLSKYLKKGNYVLVPTMFQHGRTSEFLLRIFSEVPVQLRELTLDMPKMSCWNLARG
YPKVVTQITVHSAEGLEKKYANETVNPYLVIKCGKEEVRSPVQKNTVHAIFDTQAIFYRRTTDI
PIIVQVWNSRKFCDQFLGQVTLDADPSDCRDLKSLYLRKKGGPTAKVKQGHISFKVISSDDLTE
L

hide sequence

Ensembl Acc Id:

ENSCAFP00000026850 ⟸ ENSCAFT00000028872

Ensembl Acc Id:

ENSCAFP00000053676 ⟸ ENSCAFT00000091991

RefSeq Acc Id:

XP_038380044 ⟸ XM_038524116

RefSeq Acc Id:

XP_038508536 ⟸ XM_038652608

RefSeq Acc Id:	XP_038306580 ⟸ XM_038450652
- UniProtKB:	A0A8C0SR05 (UniProtKB/TrEMBL), A0A8C0QVM2 (UniProtKB/TrEMBL), A0A8I3PJW4 (UniProtKB/TrEMBL), A0A8C0JW52 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038444020 ⟸ XM_038588092
- UniProtKB:	A0A8C0JW52 (UniProtKB/TrEMBL), A0A8C0QVM2 (UniProtKB/TrEMBL), A0A8C0SR05 (UniProtKB/TrEMBL), A0A8I3PJW4 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845030899 ⟸ ENSCAFT00845039430

Protein Domains

C2 Calpain catalytic

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000018175	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030020996	UniProtKB/TrEMBL
	ENSCAFG00040014986	UniProtKB/TrEMBL
	ENSCAFG00845022341	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000028872.5	UniProtKB/TrEMBL
	ENSCAFT00030038567.1	UniProtKB/TrEMBL
	ENSCAFT00040027621.1	UniProtKB/TrEMBL
	ENSCAFT00845039430	ENTREZGENE
	ENSCAFT00845039430.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.120.380	UniProtKB/TrEMBL
	2.60.40.150	UniProtKB/TrEMBL
	Cysteine proteinases	UniProtKB/TrEMBL
InterPro	C2_Calpain	UniProtKB/TrEMBL
	C2_dom	UniProtKB/TrEMBL
	C2_domain_sf	UniProtKB/TrEMBL
	C2_III	UniProtKB/TrEMBL
	Calpain	UniProtKB/TrEMBL
	Calpain_cysteine_protease	UniProtKB/TrEMBL
	Calpain_domain_III	UniProtKB/TrEMBL
	Calpain_III	UniProtKB/TrEMBL
	Calpain_III_sf	UniProtKB/TrEMBL
	Papain-like_cys_pep_sf	UniProtKB/TrEMBL
	Peptidase_C2_calpain_cat	UniProtKB/TrEMBL
KEGG Report	cfa:492068	UniProtKB/TrEMBL
NCBI Gene	CAPN6	ENTREZGENE
PANTHER	CALPAIN	UniProtKB/TrEMBL
	CALPAIN-6	UniProtKB/TrEMBL
Pfam	Calpain_III	UniProtKB/TrEMBL
	Peptidase_C2	UniProtKB/TrEMBL
	PF00168	UniProtKB/TrEMBL
PRINTS	CALPAIN	UniProtKB/TrEMBL
PROSITE	CALPAIN_CAT	UniProtKB/TrEMBL
	PS50004	UniProtKB/TrEMBL
SMART	calpain_III	UniProtKB/TrEMBL
	CysPc	UniProtKB/TrEMBL
	SM00239	UniProtKB/TrEMBL
Superfamily-SCOP	SSF49562	UniProtKB/TrEMBL
	SSF49758	UniProtKB/TrEMBL
	SSF54001	UniProtKB/TrEMBL
UniProt	A0A8C0JW52	ENTREZGENE
	A0A8C0QVM2	ENTREZGENE
	A0A8C0SR05	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PJW4	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:38706	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar