DRGX (dorsal root ganglia homeobox) - Rat Genome Database

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Gene: DRGX (dorsal root ganglia homeobox) Canis lupus familiaris
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Symbol: DRGX
Name: dorsal root ganglia homeobox
RGD ID: 12066834
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); sequence-specific double-stranded DNA binding (inferred); INVOLVED IN axon guidance (ortholog); axonogenesis (ortholog); detection of chemical stimulus (ortholog); ASSOCIATED WITH Cockayne syndrome B (ortholog); megacolon (ortholog); schizophrenia (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: dorsal root ganglia homeobox protein; paired related homeobox-like 1; PRRXL1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,281,868 - 1,316,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,281,864 - 1,314,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,517,204 - 1,549,503 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,458,411 - 1,490,723 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,458,330 - 1,491,350 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,256,649 - 1,288,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0281,293,756 - 1,326,052 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,425,597 - 1,457,907 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
DRGX
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,281,868 - 1,316,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,281,864 - 1,314,932 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,517,204 - 1,549,503 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,458,411 - 1,490,723 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,458,330 - 1,491,350 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1281,256,649 - 1,288,953 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0281,293,756 - 1,326,052 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0281,425,597 - 1,457,907 (-)NCBIUU_Cfam_GSD_1.0
DRGX
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381049,364,066 - 49,396,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1049,364,066 - 49,396,089 (-)EnsemblGRCh38hg38GRCh38
GRCh371050,572,111 - 50,604,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361050,244,167 - 50,269,913 (-)NCBINCBI36Build 36hg18NCBI36
Celera1044,160,334 - 44,186,078 (-)NCBICelera
Cytogenetic Map10q11.23NCBI
HuRef1044,838,688 - 44,868,588 (-)NCBIHuRef
CHM1_11050,856,344 - 50,886,243 (-)NCBICHM1_1
T2T-CHM13v2.01050,212,849 - 50,244,874 (-)NCBIT2T-CHM13v2.0
Drgx
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391432,317,824 - 32,371,203 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1432,321,364 - 32,371,203 (+)EnsemblGRCm39 Ensembl
GRCm381432,595,867 - 32,649,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,599,407 - 32,649,246 (+)EnsemblGRCm38mm10GRCm38
MGSCv371433,413,113 - 33,462,432 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361431,428,936 - 31,478,256 (+)NCBIMGSCv36mm8
Celera1428,856,722 - 28,906,126 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
Drgx
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,861,024 - 7,891,607 (+)NCBIGRCr8
mRatBN7.2167,854,849 - 7,884,404 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl167,854,849 - 7,900,600 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx167,866,810 - 7,896,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0169,011,758 - 9,041,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0167,865,781 - 7,895,587 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0168,823,872 - 8,853,430 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl168,823,872 - 8,853,430 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01610,789,700 - 10,820,026 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4168,110,849 - 8,140,551 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1168,110,846 - 8,140,549 (+)NCBI
Celera167,317,250 - 7,346,264 (-)NCBICelera
Cytogenetic Map16p16NCBI
Drgx
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955556842,714 - 870,248 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955556842,714 - 870,248 (+)NCBIChiLan1.0ChiLan1.0
DRGX
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2861,630,532 - 61,665,424 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11061,635,851 - 61,670,722 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01044,845,622 - 44,880,512 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
Drgx
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721379,687,434 - 79,722,279 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936728892,814 - 923,089 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936728892,814 - 923,089 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DRGX
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1489,942,251 - 89,976,030 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11489,941,793 - 89,975,613 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21497,851,058 - 97,884,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DRGX
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1942,415,442 - 42,447,912 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl942,416,021 - 42,445,858 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660482,169,188 - 2,201,899 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Drgx
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624928566,793 - 592,507 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624928566,405 - 592,561 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in DRGX
349 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
1 3 1 18 11 2 1 6 10 7 7 14 2

Sequence


Ensembl Acc Id: ENSCAFT00000010667   ⟹   ENSCAFP00000009888
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl281,281,864 - 1,314,932 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845036751   ⟹   ENSCAFP00845028773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl281,458,330 - 1,491,350 (-)Ensembl
RefSeq Acc Id: XM_005637482   ⟹   XP_005637539
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1281,281,868 - 1,314,687 (-)NCBI
Dog10K_Boxer_Tasha281,517,204 - 1,549,503 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038439665   ⟹   XP_038295593
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0281,458,411 - 1,490,723 (-)NCBI
RefSeq Acc Id: XM_038515643   ⟹   XP_038371571
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1281,256,649 - 1,288,953 (-)NCBI
RefSeq Acc Id: XM_038577937   ⟹   XP_038433865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0281,425,597 - 1,457,907 (-)NCBI
RefSeq Acc Id: XM_038642121   ⟹   XP_038498049
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0281,293,756 - 1,326,052 (-)NCBI
RefSeq Acc Id: XP_005637539   ⟸   XM_005637482
- UniProtKB: A0A8C0NTF5 (UniProtKB/TrEMBL),   A0A8C0R7I0 (UniProtKB/TrEMBL),   A0A8I3PDM0 (UniProtKB/TrEMBL),   A0A8C0NTA8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000009888   ⟸   ENSCAFT00000010667
RefSeq Acc Id: XP_038371571   ⟸   XM_038515643
RefSeq Acc Id: XP_038498049   ⟸   XM_038642121
RefSeq Acc Id: XP_038295593   ⟸   XM_038439665
- UniProtKB: A0A8C0NTF5 (UniProtKB/TrEMBL),   A0A8C0R7I0 (UniProtKB/TrEMBL),   A0A8I3PDM0 (UniProtKB/TrEMBL),   A0A8C0NTA8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038433865   ⟸   XM_038577937
- UniProtKB: A0A8C0NTA8 (UniProtKB/TrEMBL),   A0A8C0NTF5 (UniProtKB/TrEMBL),   A0A8C0R7I0 (UniProtKB/TrEMBL),   A0A8I3PDM0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845028773   ⟸   ENSCAFT00845036751
Protein Domains
Homeobox   OAR


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006619 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030017709 UniProtKB/TrEMBL
  ENSCAFG00040022461 UniProtKB/TrEMBL
  ENSCAFG00845020840 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010667.3 UniProtKB/TrEMBL
  ENSCAFT00030032641.1 UniProtKB/TrEMBL
  ENSCAFT00030032714.1 UniProtKB/TrEMBL
  ENSCAFT00040041698.1 UniProtKB/TrEMBL
  ENSCAFT00845036751 ENTREZGENE
  ENSCAFT00845036751.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  OAR_dom UniProtKB/TrEMBL
  Paired_Homeobox_TFs UniProtKB/TrEMBL
KEGG Report cfa:607056 UniProtKB/TrEMBL
NCBI Gene DRGX ENTREZGENE
PANTHER DORSAL ROOT GANGLIA HOMEOBOX PROTEIN UniProtKB/TrEMBL
  HOMEOBOX PROTEIN ARISTALESS UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  OAR UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  OAR UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A8C0NTA8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NTF5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R7I0 ENTREZGENE
  A0A8I3PDM0 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:40099 ENTREZGENE