LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1) - Rat Genome Database

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Gene: LYVE1 (lymphatic vessel endothelial hyaluronan receptor 1) Canis lupus familiaris
Analyze
Symbol: LYVE1
Name: lymphatic vessel endothelial hyaluronan receptor 1
RGD ID: 12066705
Description: ENCODES a protein that exhibits cargo receptor activity (inferred); hyaluronic acid binding (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN glycosaminoglycan catabolic process (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cell periphery (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: extracellular link domain containing 1; lymphatic vessel endothelial hyaluronic acid receptor 1; XLKD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12133,716,138 - 33,727,470 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2133,716,581 - 33,727,297 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2133,281,339 - 33,292,627 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02134,593,113 - 34,604,407 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2134,593,119 - 34,611,630 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12133,854,083 - 33,864,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02134,024,281 - 34,035,563 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02134,316,909 - 34,328,196 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:24593773   PMID:30032202  


Genomics

Comparative Map Data
LYVE1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12133,716,138 - 33,727,470 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2133,716,581 - 33,727,297 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2133,281,339 - 33,292,627 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02134,593,113 - 34,604,407 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2134,593,119 - 34,611,630 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12133,854,083 - 33,864,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02134,024,281 - 34,035,563 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02134,316,909 - 34,328,196 (-)NCBIUU_Cfam_GSD_1.0
LYVE1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381110,556,966 - 10,568,665 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1110,556,966 - 10,611,689 (-)EnsemblGRCh38hg38GRCh38
GRCh371110,578,513 - 10,590,212 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,535,989 - 10,546,941 (-)NCBINCBI36Build 36hg18NCBI36
Celera1110,700,953 - 10,711,906 (-)NCBICelera
Cytogenetic Map11p15.4NCBI
HuRef1110,251,901 - 10,262,854 (-)NCBIHuRef
CHM1_11110,577,487 - 10,589,311 (-)NCBICHM1_1
T2T-CHM13v2.01110,641,492 - 10,653,192 (-)NCBIT2T-CHM13v2.0
Lyve1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397110,449,814 - 110,462,160 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7110,449,814 - 110,462,446 (-)EnsemblGRCm39 Ensembl
GRCm387110,850,607 - 110,862,953 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7110,850,607 - 110,863,239 (-)EnsemblGRCm38mm10GRCm38
MGSCv377117,994,121 - 118,006,467 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367110,641,788 - 110,654,134 (-)NCBIMGSCv36mm8
Celera7110,824,675 - 110,837,013 (-)NCBICelera
Cytogenetic Map7E3NCBI
cM Map757.89NCBI
Lyve1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81174,393,387 - 174,410,977 (-)NCBIGRCr8
mRatBN7.21164,962,872 - 164,976,309 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,962,872 - 164,976,309 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1173,300,489 - 173,313,952 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01180,486,516 - 180,499,979 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01173,170,908 - 173,184,358 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01175,663,266 - 175,676,699 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1175,663,266 - 175,676,699 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,650,925 - 182,664,312 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41168,601,460 - 168,622,234 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11168,712,104 - 168,732,625 (-)NCBI
Celera1162,853,590 - 162,866,975 (-)NCBICelera
Cytogenetic Map1q33NCBI
Lyve1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541426,160,605 - 26,175,891 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541426,161,768 - 26,175,621 (-)NCBIChiLan1.0ChiLan1.0
LYVE1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2912,994,134 - 13,011,465 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11112,956,484 - 12,973,381 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01110,690,086 - 10,702,785 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11110,417,223 - 10,428,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1110,417,223 - 10,428,170 (-)Ensemblpanpan1.1panPan2
Lyve1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494751,754,473 - 51,768,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365287,788,352 - 7,802,902 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365287,788,560 - 7,802,821 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYVE1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl248,937,419 - 48,954,196 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1248,937,357 - 48,954,206 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2252,284,695 - 52,301,543 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LYVE1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1154,252,203 - 54,268,873 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl154,253,495 - 54,269,598 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038151,906,808 - 151,923,634 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lyve1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247662,633,120 - 2,648,413 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247662,634,355 - 2,648,354 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LYVE1
108 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000012136   ⟹   ENSCAFP00000011250
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2133,716,581 - 33,727,297 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000078278   ⟹   ENSCAFP00000051729
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2133,716,581 - 33,727,209 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845026314   ⟹   ENSCAFP00845020747
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2134,593,119 - 34,611,630 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845026331   ⟹   ENSCAFP00845020758
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2134,593,119 - 34,604,188 (-)Ensembl
RefSeq Acc Id: XM_003639783   ⟹   XP_003639831
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12133,716,138 - 33,727,470 (-)NCBI
Dog10K_Boxer_Tasha2133,281,339 - 33,292,627 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038430509   ⟹   XP_038286437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02134,593,113 - 34,604,407 (-)NCBI
RefSeq Acc Id: XM_038505802   ⟹   XP_038361730
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12133,854,083 - 33,864,902 (-)NCBI
RefSeq Acc Id: XM_038569036   ⟹   XP_038424964
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02134,316,909 - 34,328,196 (-)NCBI
RefSeq Acc Id: XM_038633215   ⟹   XP_038489143
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02134,024,281 - 34,035,563 (-)NCBI
RefSeq Acc Id: XP_003639831   ⟸   XM_003639783
- UniProtKB: A0A8C0M7M0 (UniProtKB/TrEMBL),   A0A8I3NYL9 (UniProtKB/TrEMBL),   A0A8P0NA08 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000051729   ⟸   ENSCAFT00000078278
Ensembl Acc Id: ENSCAFP00000011250   ⟸   ENSCAFT00000012136
RefSeq Acc Id: XP_038361730   ⟸   XM_038505802
RefSeq Acc Id: XP_038489143   ⟸   XM_038633215
RefSeq Acc Id: XP_038286437   ⟸   XM_038430509
- UniProtKB: A0A8C0M7M0 (UniProtKB/TrEMBL),   A0A8I3NYL9 (UniProtKB/TrEMBL),   A0A8P0NA08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038424964   ⟸   XM_038569036
- UniProtKB: A0A8C0M7M0 (UniProtKB/TrEMBL),   A0A8I3NYL9 (UniProtKB/TrEMBL),   A0A8P0NA08 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845020758   ⟸   ENSCAFT00845026331
Ensembl Acc Id: ENSCAFP00845020747   ⟸   ENSCAFT00845026314
Protein Domains
Link

Promoters
RGD ID:13687250
Promoter ID:EPDNEW_C5316
Type:initiation region
Name:LYVE1_1
Description:lymphatic vessel endothelial hyaluronan receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12133,727,337 - 33,727,397EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007580 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030004683 UniProtKB/TrEMBL
  ENSCAFG00040012658 UniProtKB/TrEMBL
  ENSCAFG00845014712 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012136.4 UniProtKB/TrEMBL
  ENSCAFT00000078278.2 UniProtKB/TrEMBL
  ENSCAFT00030008612.1 UniProtKB/TrEMBL
  ENSCAFT00030008636.1 UniProtKB/TrEMBL
  ENSCAFT00040023329.1 UniProtKB/TrEMBL
  ENSCAFT00040023357.1 UniProtKB/TrEMBL
  ENSCAFT00040023389.1 UniProtKB/TrEMBL
  ENSCAFT00845026314 ENTREZGENE
  ENSCAFT00845026314.1 UniProtKB/TrEMBL
  ENSCAFT00845026331.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
InterPro C-type_lectin-like/link_sf UniProtKB/TrEMBL
  CD44_antigen-like UniProtKB/TrEMBL
  CTDL_fold UniProtKB/TrEMBL
  Link_dom UniProtKB/TrEMBL
KEGG Report cfa:100855439 UniProtKB/TrEMBL
NCBI Gene LYVE1 ENTREZGENE
PANTHER LYMPHATIC VESSEL ENDOTHELIAL HYALURONIC ACID RECEPTOR 1 UniProtKB/TrEMBL
  PTHR10225 UniProtKB/TrEMBL
Pfam Xlink UniProtKB/TrEMBL
PRINTS LINKMODULE UniProtKB/TrEMBL
PROSITE LINK_1 UniProtKB/TrEMBL
  LINK_2 UniProtKB/TrEMBL
SMART LINK UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/TrEMBL
UniProt A0A8C0M7M0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0RCQ5_CANLF UniProtKB/TrEMBL
  A0A8C0SEH8_CANLF UniProtKB/TrEMBL
  A0A8I3NYL9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RYB7_CANLF UniProtKB/TrEMBL
  A0A8P0NA08 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:42900 ENTREZGENE