HTR5A (5-hydroxytryptamine receptor 5A) - Rat Genome Database

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Gene: HTR5A (5-hydroxytryptamine receptor 5A) Canis lupus familiaris
Analyze
Symbol: HTR5A
Name: 5-hydroxytryptamine receptor 5A
RGD ID: 12065706
Description: ENCODES a protein that exhibits G protein-coupled serotonin receptor activity (ortholog); INVOLVED IN adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (ortholog); hippocampus development (ortholog); ASSOCIATED WITH autistic disorder (ortholog); holoprosencephaly 3 (ortholog); intracranial hypertension (ortholog); FOUND IN dendrite (ortholog); perikaryon (ortholog); postsynaptic specialization membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,142,808 - 18,151,884 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,142,830 - 18,152,442 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1618,774,961 - 18,784,567 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01619,870,711 - 19,880,323 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1619,870,775 - 19,881,072 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,241,740 - 18,251,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01618,821,984 - 18,831,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01618,874,866 - 18,884,472 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HTR5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,142,808 - 18,151,884 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,142,830 - 18,152,442 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1618,774,961 - 18,784,567 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01619,870,711 - 19,880,323 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1619,870,775 - 19,881,072 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11618,241,740 - 18,251,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01618,821,984 - 18,831,569 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01618,874,866 - 18,884,472 (+)NCBIUU_Cfam_GSD_1.0
HTR5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387155,070,324 - 155,087,392 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7155,070,324 - 155,087,392 (+)EnsemblGRCh38hg38GRCh38
GRCh377154,862,034 - 154,879,102 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,493,479 - 154,508,392 (+)NCBINCBI36Build 36hg18NCBI36
Build 347154,300,257 - 154,313,845NCBI
Celera7149,280,016 - 149,294,949 (+)NCBICelera
Cytogenetic Map7q36.2NCBI
HuRef7148,594,438 - 148,611,518 (+)NCBIHuRef
CHM1_17154,870,423 - 154,887,497 (+)NCBICHM1_1
T2T-CHM13v2.07156,245,922 - 156,265,002 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27154,090,358 - 154,107,446 (+)NCBI
Htr5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,046,836 - 28,059,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl528,047,147 - 28,060,086 (+)EnsemblGRCm39 Ensembl
GRCm38527,841,716 - 27,855,086 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl527,842,149 - 27,855,088 (+)EnsemblGRCm38mm10GRCm38
MGSCv37528,168,487 - 28,181,626 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36528,172,734 - 28,185,873 (+)NCBIMGSCv36mm8
Celera525,390,567 - 25,404,062 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map513.24NCBI
Htr5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr848,178,802 - 8,188,485 (-)NCBIGRCr8
mRatBN7.247,444,968 - 7,454,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl47,444,968 - 7,454,651 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx412,455,005 - 12,464,692 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.048,269,250 - 8,278,935 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.046,615,442 - 6,625,127 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04199,916 - 209,599 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4199,916 - 209,599 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04192,554 - 202,795 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,707,261 - 2,716,944 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.142,707,260 - 2,716,944 (-)NCBI
Celera42,826,290 - 2,835,975 (+)NCBICelera
Cytogenetic Map4q11NCBI
Htr5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554918,257,698 - 8,267,817 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554918,258,032 - 8,266,503 (+)NCBIChiLan1.0ChiLan1.0
HTR5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26191,499,178 - 191,516,265 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1743,509,446 - 43,526,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07146,672,908 - 146,690,001 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17158,399,874 - 158,416,922 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7158,399,874 - 158,416,922 (+)Ensemblpanpan1.1panPan2
Htr5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051183,356,644 - 3,369,173 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365279,534,903 - 9,543,574 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365279,534,723 - 9,547,235 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HTR5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1183,029,681 - 3,033,646 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2183,211,397 - 3,219,097 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HTR5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121123,229,239 - 123,244,360 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21123,229,816 - 123,241,481 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607219,276,174 - 19,365,766 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Htr5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248002,618,973 - 2,625,559 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248002,616,861 - 2,625,907 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HTR5A
202 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000008169   ⟹   ENSCAFP00000007567
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,142,830 - 18,152,442 (+)Ensembl
Ensembl Acc Id: ENSCAFT00845023034   ⟹   ENSCAFP00845018059
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1619,870,775 - 19,881,072 (+)Ensembl
RefSeq Acc Id: XM_014119982   ⟹   XP_013975457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11618,142,808 - 18,151,884 (+)NCBI
Dog10K_Boxer_Tasha1618,774,961 - 18,784,567 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038498092   ⟹   XP_038354020
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11618,241,740 - 18,251,355 (+)NCBI
RefSeq Acc Id: XM_038559222   ⟹   XP_038415150
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01618,874,866 - 18,884,472 (+)NCBI
RefSeq Acc Id: XM_038623171   ⟹   XP_038479099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01618,821,984 - 18,831,569 (+)NCBI
RefSeq Acc Id: XM_038688910   ⟹   XP_038544838
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01619,870,711 - 19,880,323 (+)NCBI
RefSeq Acc Id: XP_013975457   ⟸   XM_014119982
- UniProtKB: A0A8C0NXC7 (UniProtKB/TrEMBL),   A0A8C0JW84 (UniProtKB/TrEMBL),   A0A8I3NMV4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000007567   ⟸   ENSCAFT00000008169
RefSeq Acc Id: XP_038354020   ⟸   XM_038498092
RefSeq Acc Id: XP_038479099   ⟸   XM_038623171
RefSeq Acc Id: XP_038544838   ⟸   XM_038688910
- UniProtKB: A0A8C0NXC7 (UniProtKB/TrEMBL),   A0A8C0JW84 (UniProtKB/TrEMBL),   A0A8I3NMV4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038415150   ⟸   XM_038559222
Ensembl Acc Id: ENSCAFP00845018059   ⟸   ENSCAFT00845023034

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005077 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030019255 UniProtKB/TrEMBL
  ENSCAFG00040011270 UniProtKB/TrEMBL
  ENSCAFG00845012951 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000008169.5 UniProtKB/TrEMBL
  ENSCAFT00030035390.1 UniProtKB/TrEMBL
  ENSCAFT00040020812.1 UniProtKB/TrEMBL
  ENSCAFT00845023034 ENTREZGENE
  ENSCAFT00845023034.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 5HT5A_rcpt UniProtKB/TrEMBL
  5HT_rcpt UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
KEGG Report cfa:482814 UniProtKB/TrEMBL
NCBI Gene HTR5A ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR 5A UniProtKB/TrEMBL
  ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS 5HT5ARECEPTR UniProtKB/TrEMBL
  5HTRECEPTOR UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0JW84 ENTREZGENE
  A0A8C0NXC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3NMV4 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41832 ENTREZGENE