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Gene: SC5D (sterol-C5-desaturase) Pan paniscus

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Symbol:

SC5D

Name:

sterol-C5-desaturase

RGD ID:

12048774

Description:

ENCODES a protein that exhibits C-5 sterol desaturase activity (ortholog); INVOLVED IN cholesterol biosynthetic process via lathosterol (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH CD3epsilon deficiency (ortholog); chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

lathosterol oxidase; lathosterol oxidase-like; SC5DL; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SC5D (sterol-C5-desaturase)	NCBI	Ortholog
Mus musculus (house mouse):	Sc5d (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Sc5d (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sc5d (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SC5D (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sc5d (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SC5D (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SC5D (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sc5d (sterol-C5-desaturase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	122,007,595 - 122,023,751 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	123,110,665 - 123,131,599 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	116,139,979 - 116,160,745 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	120,063,557 - 120,084,297 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	120,063,743 - 120,078,386 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

CD3epsilon deficiency (ISO)

chromosome 11 partial duplication syndrome (ISO)

Dwarfism (ISO)

genetic disease (ISO)

immunodeficiency 17 (ISO)

immunodeficiency 18 (ISO)

immunodeficiency 19 (ISO)

inflammatory bowel disease 28 (ISO)

intellectual disability (ISO)

isolated microphthalmia 5 (ISO)

Lathosterolosis (ISO)

liver disease (ISO)

RASopathy (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol biosynthetic process via lathosterol (IEA,ISO)

lipid biosynthetic process (IEA)

negative regulation of ferroptosis (IEA)

Cellular Component

endoplasmic reticulum membrane (IEA,ISO)

membrane (IEA)

Molecular Function

C-5 sterol desaturase activity (ISO)

delta7-sterol 5(6)-desaturase activity (IEA)

iron ion binding (IEA)

oxidoreductase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SC5D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	122,007,595 - 122,023,751 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	123,110,665 - 123,131,599 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	116,139,979 - 116,160,745 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	120,063,557 - 120,084,297 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	120,063,743 - 120,078,386 (+)	Ensembl	panpan1.1		panPan2

SC5D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	121,292,771 - 121,313,410 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	121,292,681 - 121,313,410 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	121,163,480 - 121,184,119 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	120,668,598 - 120,689,329 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	120,668,707 - 120,684,556	NCBI
Celera	11	118,322,556 - 118,343,287 (+)	NCBI		Celera
Cytogenetic Map	11	q23.3-q24.1	NCBI
HuRef	11	117,104,038 - 117,124,769 (+)	NCBI		HuRef
CHM1_1	11	121,050,565 - 121,071,293 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	11	121,317,829 - 121,338,469 (+)	NCBI		T2T-CHM13v2.0

Sc5d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	42,162,888 - 42,175,607 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	42,162,891 - 42,175,552 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	42,251,592 - 42,264,300 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	42,251,595 - 42,264,256 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	42,062,260 - 42,072,383 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	42,005,172 - 42,015,228 (-)	NCBI		MGSCv36	mm8
Celera	9	39,502,932 - 39,513,104 (-)	NCBI		Celera
Cytogenetic Map	9	A5.1	NCBI
cM Map	9	23.57	NCBI

Sc5d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	51,526,669 - 51,538,277 (-)	NCBI		GRCr8
mRatBN7.2	8	42,629,649 - 42,641,257 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	42,632,672 - 42,641,273 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	48,126,129 - 48,135,073 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	46,404,794 - 46,413,738 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	44,272,388 - 44,281,332 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	46,525,406 - 46,537,014 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	46,525,400 - 46,537,050 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	44,998,826 - 45,010,434 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	45,229,976 - 45,238,924 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	45,238,758 - 45,247,690 (-)	NCBI
Celera	8	42,225,268 - 42,234,215 (-)	NCBI		Celera
Cytogenetic Map	8	q22	NCBI

Sc5d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	22,274,250 - 22,288,870 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	22,274,131 - 22,288,870 (+)	NCBI	ChiLan1.0	ChiLan1.0

SC5D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	12,760,591 - 12,774,484 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	12,763,286 - 12,775,393 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	12,813,437 - 12,829,449 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	12,708,566 - 12,724,659 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	12,710,727 - 12,724,612 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	12,815,057 - 12,831,074 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	12,751,628 - 12,767,860 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	12,789,890 - 12,805,983 (-)	NCBI		UU_Cfam_GSD_1.0

Sc5d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	103,124,991 - 103,141,416 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936542	6,046,390 - 6,059,074 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936542	6,046,425 - 6,062,825 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SC5D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	48,357,165 - 48,372,386 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	48,357,115 - 48,372,391 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	53,564,379 - 53,580,339 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SC5D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	112,706,511 - 112,720,860 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	112,706,545 - 112,719,722 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	13,365,816 - 13,384,119 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sc5d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624880	3,874,337 - 3,896,721 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003819972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003819973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063608292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000065738 ⟹ ENSPPAP00000042806

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	120,063,743 - 120,078,386 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000065740 ⟹ ENSPPAP00000042808

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	120,074,251 - 120,078,386 (+)	Ensembl

RefSeq Acc Id:

XM_003819972 ⟹ XP_003820020

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	122,007,595 - 122,023,751 (+)	NCBI
NHGRI_mPanPan1	11	123,110,665 - 123,131,599 (+)	NCBI
Mhudiblu_PPA_v0	11	116,139,979 - 116,160,745 (+)	NCBI
PanPan1.1	11	120,063,557 - 120,084,297 (+)	NCBI

Sequence:

show sequence

TTCGCGCGATCTGCCGTCATATCAGCTTATGGCGCCGGTCGCTGATTGGCTGGCAGCTCCAGCC
TCCCGGCCCGCTTGCTGGCTGCCCAGCTGCTAGGGCAGTTTGCAGAGCAGTGGCGTGCGGAGCG
GCGGCGGACCACCTCCAGGGGCTAAGTGATGGATCTTGTACTCAGTGTTGCAGATTACTATTTT
TTTACACCATACATGTATCCAGCCACATGGCCAGAAGATGACATCTTCCGACAAGCTATTAGTC
TTCTGATTGTAACAAATGTTGGTGCTTACATCCTTTATTTCTTCTGTGCAACACTGAGCTATTA
TTTTGTCTTCGATCATGCATTAATGAAACATCCACAATTTTTAAAGAATCAAGTCCGTCGAGAG
ATTAAGTTTACTGTCCAGGCATTGCCATGGATAAGTATTCTTACTGTTGCACTGTTCTTGCTGG
AGATAAGAGGTTATAGCAAATTACATGATGACCTAGGAGAGTTTCCATATGGATTGTTTGAACT
TGTCGTTAGTGTAATATCTTTCCTCTTTTTCACTGACATGTTCATCTACTGGATTCACAGAGGC
CTTCATCATAGACTGGTATATAAGCGCCTACATAAACCTCACCATGTTTGGAAGATTCCTACTC
CATTTGCAAGTCATGCTTTTCACCCTATTGATGGCTTTCTTCAGAGTCTACCTTACCATATATA
CCCTTTTATCTTTCCATTACACAAGGTGGTTTATTTAAGTCTGTACATCTTGGTTAATATCTGG
ACAATTTCCATTCATGACGGTGATTTTCGTGTCCCCCAAATCTTACAGCCATTTATTAATGGCT
CAGCTCATCATACAGACCACCATATGTTCTTTGACTATAATTATGGACAATATTTCACTTTGTG
GGATAGGATTGGCGGCTCATTCAAAAATCCTTCGTCCTTTGAGGGGAAGGGACCGCTCAGTTAC
GTGAAGGAGATGACAGAGGGAAAGCGCAGCAGCCATTCAGGAAATGGCTGTAAGAATGAAAAAT
TATTCAATGGAGAGTTTACAAAGACTGAATAGATTATTGCCCAGTTATTCTTAAGTAAGGGACA
AAGAAGGAAATATCATCGTATTTCTTTTTTTAATAAGGAAAAAATAATCTCCATACAGTCAAGA
TACATAGTAAATGGTATCATTTGGAAATCAGCATCGTGGGCACTGCTGAGGAATGATCCTAGTG
GTAGGTCAGAAGAAGATGCTGTGAACACCAGGACTTTAATCTTATGCTTAAAATGCCAGATGTT
GTTCGGGGGACAACTTGTATCTTTCTAGCAGCAGATCTGTAGTTTGTATAGCCTCAACAACAAT
TTTAAATAAGATGGAGAATAAATTATTGAGGGGACTAGGCTATATGCATTTGCCTTTATCCACC
CATGTTTATTAAGAATCATTGTGCTTAATAATACCAAGACTAAGCACCATAACCAAGAAATACT
AATGTAAAGATTGTTTCTTGTTTCCGGAATGGTTAATTCTTCAACGTTGGTATGATAATGATAA
CTTGTAGTACTTTATTCAAGTCAAAACATCAGTGTGGAAAAAAATTCTGATACATTAGCAGCTA
TGTAAATGACCTAATTGATAGCAGGTGTAATAAGACTATCGTCTTCCTACACATAGGAGGCTCA
TTCTCTGGACACACTATCACCTATTACATTTTACTGATTAACAAATAAATTGGAATTTAAAAAT
ATTGATATCACCATGATTTAATCCAGATCTGGGATTATGTAACTAAACATTGTGATGATTATTA
TTTAAAACCATTATTTAATAAGAGTAAAAATATGTGAATCTGGATATATTTAAAAAAGAAATTT
GATGCCCAGATAATATATTGGGCACTGCTGATTTTTTAGTTAAATTGATGCACTACACTTTTGA
TGTTTGAAGTTACAAACCTGTAATTTTTTTGTAAAGGAAATAATTGCCAAATACCTAGGCCCAT
TGCTGACAATTAGTTCTAAAATCTTATTCCTCCTCTTCTCCCCTCACTTTTCCCTACTTCCTCT
GCAAAAAGATTTAACAAATACATTCATAAGGAAATGTGTGTTGTAACAAATATATTGCAAAAAC
ATAGTTTGTAAAGGCATTCTATAAGCTATTTATGTAAAATCAATAAAAGTTGATCATAATTAAA
CTGTATCAGTTGAATATTATAGCAGCACAAAGTATTCTCTGTACAGATTTTGTGCCAATTTGAA
GCCACAGAAATGATGTGGATTGTTAATTGTGTTTTAGAACATCCCCGGACACTCAGTGTCACAG
GGGGAAAGAAGTGGGTACCACATTCTGTTTATTTATATTTCACATTTTAACTAGATTTGAGTGT
TTTTAGCAAGAAATCAGTCTTAAAATCTAATGTCTGGGATCCAGAAGAAAATGTCTTTAATCTG
TGAGTTATTGTCACAATGTCATCTTATTTAAATGTACCAATTAGCATTTTGTAATAGGCAAATG
TCATTTAGTGCTTTTCACCAATCCCACTCGCCCCCGGTGCTCCGCCTTGCCTAAGAAAAAGAAA
TTAAGGAGAAGTAAACTTTATTTCCTAATATAATGTCAGCTGATATTTATTGAGCTTTTCCTCT
TTGCCCAGAGACTAGGACCCAAAGAAGTTAAGTAACTATTCCCAGGTTTATTTCTCTCTCATAT
AATGTCCCATGTGGATGTTTGTGGTCAGTGGACAGCTTTCCACCTAGTCTTTCTGCGACCCAGG
CTCCTTCCTCTTGGGGCTCTGCCTTTCTCTCAGTCCATAGAGCCCTCTTTGTTGAAAGAGCACA
TAGGAAAAGAAGGAAAAGTCTGTGTGGAAAATGTTTCTGGGTCAGGCCTGGAAGTGGTGCATAT
CTCTTCCGCCCATGTTCCTTTGGACAGAACTCCGTCACATGGCCCACCTAGAGAGATTTTGGGA
AATGTGTCCAGCTGTGTGCCTGGGAGGAAGGGGGCACCATTTTCTTGAGCAGCTAGACAGTTTG
CTGTATTTGTGTTGTTCTCCTCTTGTTGATGTTGAAATGGTGAATGAGCCATAAAGTATTTCAG
GTTATCCACACACTAATCATCTCAGTGTCTTTAATTCTTAACTCCAATATGAATGTTTAAAGCT
TCCTCTAGATTCTTATTCCTATATAACTAATAGAGAAGAAAGGACAGCTTCCTATGGGGAAGAC
GGAGGCTTCCTCGTAGATGTTAGGAATAATCAAACTTGCCCCTGCCCTTTCACCCATCTCAAAT
TCTGGTCTTTTAAAGCAGCGTTATGTTAAGTAGTCCTAACATTGTAATATACAGTACTGCCACA
TTCTCCTACTTTCTATTAGAGGAAGTCAGAGAATATGGAAGTGAGGACCCAAATTACCTTCTAC
AGATGACTTTGAAACCTTTTATAGTTACAGGACAGAAAGTGAAAATCAAGGTTATGTTTTCTAC
TTTTGTGGTAGAAATTGAGAAGTGGGTGGATATGGTTCGAGAAGACCTTTCAGAAACACAGAGA
CTGAGTCTTTGTCTTCCATGCTGTCTCTGCAGTACTGAGTGAATTTCCTTATACCCTTGTATCA
TGTTTTCCTCCCATCTTCTAGAAGCTGGGGACAGATTTGGAAGAGAATTGCACAAGTTCAGTTT
TTTGATACATGGATTTTACAGTGCATGCAGGTTATTTATGTAGAGAGGAGGTCTGGGAGAAAGA
TGGAAACTAGGGAGATGACTGAGAACAAAGATATTTGGGATTAACACAGATAGAAGAAAAGTTT
GAAACCATGAGATTGTCACAGCATGAAAAAAGATATTCAAAGACACTAACCAACTTGAGGGGTG
CAGTGGTCTGAATGTGTCCTCCAAAATTCAAATGTGGAAATGTATTTGCCAGTGAGATAGTGTG
TAGAGGTGGGGCCTTGAGGAAGTGATTAAGTCATGAGGGCTCTGGGATTAATGACTTAAAAAGA
GGTGTGAGGCAGCTGTTCAGCCCTTCTGTCTCCTGTCCCTTTTTTTTTTTTTTTTTATGAGATG
GAGTCTTGCTCTGTTGCCCCAGGCTGGAGTGCAGTGGCGTGATCTTGGTTCACTGCAAGCTCCA
CCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGTCCGC
CACCACCAAGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAG
GATGGTCTTCATCTCCTGACCTCGTGATCTGCCTGCCTCGGCCTCCCAGAGTGCTGGGATTATA
GGTGTGAGCCACCATGCCCAGCCCCTTCTGTCCCTTCTAACGTGAGGACCCAGCAACAAGGTAC
CATCTTGAAAGCAGCAACTGGGGACTCAGCAGACACCAAACCAACTGGTGCTTAACCGTGACTT
CCCAGCCCCCAGAGCTGTAAGAAAATAAATTTCTATTATTTATAGATTACCCAGTTGAAGATAC
TTTGTTAAGGCAGTACAAATGGACTAAGACAAGGGGGAAGAAATTTGCATTCCTGATCTTCCCA
ACTTCTTCAAATTCACAACACTTGAATGACAGTCTTATTTCAGCACCTACTGCTATCACCTATT
ACTTTTATGTGTGTCTTACCTATTTGAGATGCCAGATTCCTTGGAAGTAGAGACCGTGTCTGAA
TCATCATTGTATTAAACCACTCATCCTTAACAAATGCCCAAGCCATGGTTAAAGTTCAATAAAT
ACTTTGTTGAATTTATTAATAAAATGGCAGAAATGTCATTCTCTTCCATATATGTTTCATAAAT
CCCTGATAGGTGCTAAGCACTGCACTAGGTAAAAATTCTCTTCTGATGCTGTCTTTTTGGCTAA
CCATTTTTTTTTATCATTTATTCATTAGCTGACATTTGCTAAGTGCTTTGGAGGGGTCAAAAGG
GGAAGTAATGAGAAATCAAAGATGGTCCCTACATCAAGGATAAACTATCTTTTTTTAGTCACTC
AAAGTCATAACCCTTTGGAAACAAAACCCACCAGTACCCCAGATTTTGACCACAGATGAATCAG
TACTACAAGGACTGGTTAGAGGGTTGAATGAATCTGTATACTCAGCACTTAACACAGCACTCTG
GGTAAAAGAAAAAAGATCCTCAAAGATATTAGTTGGTTACATCAAGAAAGGACAAACTTAGGTT
AATCTATAACTTCATCTCAGAGGAACAGGAACTTTGGAGATAAACAGGGCTCTGCCACTTGCAA
GTTGCACCATCCTGGTTTCTCCATCTGTAAATTGATTAAAACACTGCCTGTCTAATAAGATTAA
ATAAGTTAGAAGCATTCAGTTAAATGTCAACTGAAACTATTGTTCATGTAAATTGTGCTTGACG
CTTTTTCTTTCTAGATTCAATGATTATTGTCATTTTACCTCGATAGGCCCTCAATAGAAATCAG
TTGCAGAGGGCAGAAGCCTAGATATTTTCACCTTAAAATTGGAGGGCGAAAGACATTGAGGTGA
AGTAGAGATAGAGGGTACACAGAAAAATCGTATAAGTAAAACTAACATCGTTAACATTATTTAC
TGTAAGTTATCTTTGTAAGAGTGGTAAAATACATTATGTGTTGTTAAATAATTTCATTTAAAAA
ATGCATCACTTTGTGTGTTTTTATATTGCTAAAACCATAAGGCCAGTCTACAAGGTTTGTAGAT
AAAATAGGAACATACCTTCCTTGAAAAGCAGAATAAATTTTTTAAAGGCAGGAAGGAAGTGTTT
GAACCATGTGTCAACAAGCTTTACTGTCAAAGCAGGCTTTTGATATGGAAAGAAAAATACTTAT
AAATACTTGTTTTAATATTTGCTTTATTAAAATACATTTAAAATACAGCATTTTTAAATCTCTA
AGCTCAACTTGAAGATATAAGAACAGTAAATTTGATAAAAAGGAGAAATTACATTCCCATTTCT
TTAACAATTTGTAAATTCCAATTATCCTGAACATTTAATACCATTTACATATTTTATTAATCAC
ATTTTCTTAAACATTTGATAAGAGATTTAATATTTTGATCCAACTACCAAAAAAGCAGACTTGT
GTACTTGACAGATTTTTCTAAACACTTCACAACTCACGATTCAAACATAAAGACAAAATAGCAT
ATCAAAAGTTAATCACTCAGTTGGAAAGCATTCATACCATAGGCTTTTATTCATTTCTTGAATA
ATTTTGTTATGTCTTCCTCTTTTAGGCTGCAATGAGCTATAATTGCACTACTGCACTCCACGCT
GGGTGACAGAGCAAGACCCTATCTCTAAAAATAAAAAAGTATATATATATAAAAATATCTTCCT
CTATTATAGTTTAACTCATTAAGCCATTTATTTAGATGGAAACTTGCCCCCCTGACATGTGCTA
TGAAACAAATAGAAACCTAGAAATTTAGTGCACATTCAAATATTAAGACAGACACTGGTGTGGT
GACTTTTGTCTGTCGCTTCATTGGGACGTTTTTTCTTTCTGATCAACTTAATGAAATTATAATT
TACTATAATTAAGTGTAGCCATTTTTACTGTAGAGTTCAATGATCTTTGATGAACGTGTACACC
CATGTAACCACCACCCCCAATCAAAGTAAAGAACATTTTCCTACCAGAATAAATTTCCTCTCCC
TTTGCAGTCATTCTCCCCAGCCCTAGGTCACCACTGATCCACCTTCTGTTACTGGAAGGTTAGT
TTTCTTCCCTGATTTAGAATTTCATATAAATTAAATCAGATAGTATATACTCTTGTGTTTAGTT
TCTTTAGCTTAACATGTTTAGAGATACTTGCTGTTGCCTGTGTCTGTAGCTTTTTGTTTTCATT
GCTGAATAGTATTTCATTGTAATATACCACAGTTGGTTTACGTATTTGCTGATGAATATTTGTG
TTATTTCCAGTGTGGGATTATTATGAATAAAGTTGCTACAAACATTTGTGTACAA

hide sequence

RefSeq Acc Id:

XM_063608292 ⟹ XP_063464362

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	122,007,976 - 122,023,751 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003820020	(Get FASTA)	NCBI Sequence Viewer
	XP_063464362	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000042806.1
	ENSPPAP00000042808.1

RefSeq Acc Id:

XP_003820020 ⟸ XM_003819972

- UniProtKB:

A0A2R9CLH4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDLVLSVADYYFFTPYMYPATWPEDDIFRQAISLLIVTNVGAYILYFFCATLSYYFVFDHALMK
HPQFLKNQVRREIKFTVQALPWISILTVALFLLEIRGYSKLHDDLGEFPYGLFELVVSVISFLF
FTDMFIYWIHRGLHHRLVYKRLHKPHHVWKIPTPFASHAFHPIDGFLQSLPYHIYPFIFPLHKV
VYLSLYILVNIWTISIHDGDFRVPQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKN
PSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTKTE

hide sequence

Ensembl Acc Id:

ENSPPAP00000042806 ⟸ ENSPPAT00000065738

Ensembl Acc Id:

ENSPPAP00000042808 ⟸ ENSPPAT00000065740

RefSeq Acc Id:	XP_063464362 ⟸ XM_063608292
- UniProtKB:	A0A2R9CLH4 (UniProtKB/TrEMBL)

Protein Domains

Fatty acid hydroxylase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000043959	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000065738.1	UniProtKB/TrEMBL
	ENSPPAT00000065740.1	UniProtKB/TrEMBL
InterPro	Fatty_acid_hydroxylase	UniProtKB/TrEMBL
	Sterol_Desaturase_Related	UniProtKB/TrEMBL
KEGG Report	pps:100979606	UniProtKB/TrEMBL
NCBI Gene	SC5D	ENTREZGENE
PANTHER	FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2-RELATED	UniProtKB/TrEMBL
	STEROL DESATURASE	UniProtKB/TrEMBL
Pfam	FA_hydroxylase	UniProtKB/TrEMBL
UniProt	A0A2R9CLH4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9CNK3_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB