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Gene: SC5D (sterol-C5-desaturase) Homo sapiens
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Symbol: SC5D
Name: sterol-C5-desaturase
Description: Exhibits C-5 sterol desaturase activity. Predicted to be involved in cholesterol biosynthetic process via lathosterol. Predicted to localize to endoplasmic reticulum membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3beta-hydroxysteroid-delta5-desaturase; C-5 sterol desaturase; delta(7)-sterol 5(6)-desaturase; delta(7)-sterol 5-desaturase; delta(7)-sterol C5(6)-desaturase; ERG3; fungal ERG3, delta-5-desaturase-like; lathosterol 5-desaturase; lathosterol dehydrogenase; lathosterol oxidase; S5DES; SC5DL; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
Orthologs:
Mus musculus (house mouse) : Sc5d (sterol-C5-desaturase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sc5d (sterol-C5-desaturase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sc5d (sterol-C5-desaturase)
Pan paniscus (bonobo/pygmy chimpanzee) : SC5D (sterol-C5-desaturase)
Canis lupus familiaris (dog) : SC5D (sterol-C5-desaturase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sc5d (sterol-C5-desaturase)
Sus scrofa (pig) : SC5D (sterol-C5-desaturase)
Chlorocebus sabaeus (African green monkey) : SC5D (sterol-C5-desaturase)
Heterocephalus glaber (naked mole-rat) : Sc5d (sterol-C5-desaturase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11121,292,681 - 121,313,410 (+)EnsemblGRCh38hg38GRCh38
GRCh3811121,292,771 - 121,313,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711121,163,388 - 121,184,119 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611120,668,598 - 120,689,329 (+)NCBINCBI36hg18NCBI36
Build 3411120,668,707 - 120,684,556NCBI
Celera11118,322,556 - 118,343,287 (+)NCBI
Cytogenetic Map11q23.3-q24.1NCBI
HuRef11117,104,038 - 117,124,769 (+)NCBIHuRef
CHM1_111121,050,565 - 121,071,293 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on SC5D
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351356
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.