P3H2 (prolyl 3-hydroxylase 2) - Rat Genome Database

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Gene: P3H2 (prolyl 3-hydroxylase 2) Pan paniscus
Analyze
Symbol: P3H2
Name: prolyl 3-hydroxylase 2
RGD ID: 12042271
Description: ENCODES a protein that exhibits dioxygenase activity (inferred); iron ion binding (inferred); L-ascorbic acid binding (inferred); INVOLVED IN peptidyl-proline hydroxylation (ortholog); ASSOCIATED WITH genetic disease (ortholog); High Myopia with Cataract and Vitreoretinal Degeneration (ortholog); intestinal disease (ortholog); FOUND IN basement membrane (inferred); cytosol (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: leprecan-like 1; LEPREL1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22187,822,467 - 187,990,737 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13187,827,183 - 187,995,467 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03186,976,926 - 187,141,678 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13195,532,341 - 195,695,510 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,533,511 - 195,695,598 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
P3H2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22187,822,467 - 187,990,737 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13187,827,183 - 187,995,467 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03186,976,926 - 187,141,678 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13195,532,341 - 195,695,510 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3195,533,511 - 195,695,598 (-)Ensemblpanpan1.1panPan2
P3H2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383189,956,728 - 190,122,278 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3189,956,728 - 190,122,437 (-)EnsemblGRCh38hg38GRCh38
GRCh373189,674,517 - 189,840,067 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363191,157,316 - 191,321,412 (-)NCBINCBI36Build 36hg18NCBI36
Build 343191,157,323 - 191,321,420NCBI
Celera3188,102,461 - 188,268,906 (-)NCBICelera
Cytogenetic Map3q28NCBI
HuRef3187,072,503 - 187,237,981 (-)NCBIHuRef
CHM1_13189,637,377 - 189,803,103 (-)NCBICHM1_1
T2T-CHM13v2.03192,773,118 - 192,938,644 (-)NCBIT2T-CHM13v2.0
P3h2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391625,778,034 - 25,924,563 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1625,778,038 - 25,924,534 (-)EnsemblGRCm39 Ensembl
GRCm381625,959,284 - 26,105,813 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1625,959,288 - 26,105,784 (-)EnsemblGRCm38mm10GRCm38
MGSCv371625,960,409 - 26,105,870 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361625,875,672 - 26,021,133 (-)NCBIMGSCv36mm8
Celera1626,503,926 - 26,649,250 (-)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1617.63NCBI
P3h2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81188,139,086 - 88,280,221 (+)NCBIGRCr8
mRatBN7.21174,634,267 - 74,775,422 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,634,267 - 74,775,421 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1183,443,019 - 83,584,372 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01176,078,068 - 76,219,425 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01175,139,871 - 75,281,175 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01178,028,885 - 78,169,746 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,029,038 - 78,169,648 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01182,549,554 - 82,690,068 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,687,437 - 76,828,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,745,025 - 76,886,374 (+)NCBI
Celera1173,544,026 - 73,685,131 (+)NCBICelera
Cytogenetic Map11q22NCBI
P3h2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542017,964,153 - 18,117,095 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542017,964,153 - 18,118,442 (+)NCBIChiLan1.0ChiLan1.0
P3H2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13422,035,124 - 22,185,146 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3422,023,068 - 22,185,026 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3426,128,347 - 26,278,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03421,969,192 - 22,119,559 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3421,967,663 - 22,119,559 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13421,984,404 - 22,141,097 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03421,977,205 - 22,127,973 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03422,219,915 - 22,370,251 (-)NCBIUU_Cfam_GSD_1.0
P3h2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602114,177,035 - 114,339,277 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936578268,856 - 431,137 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936578268,815 - 431,123 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P3H2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13127,414,958 - 127,572,163 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113127,414,955 - 127,572,165 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213136,665,659 - 136,863,053 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P3H2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11584,185,288 - 84,348,186 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1584,185,299 - 84,348,011 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604157,767,198 - 57,931,651 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P3h2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473067,072,478 - 67,228,599 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473067,072,389 - 67,228,207 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003824964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000057214   ⟹   ENSPPAP00000034333
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl3195,533,511 - 195,695,598 (-)Ensembl
RefSeq Acc Id: XM_003824964   ⟹   XP_003825012
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22187,822,467 - 187,990,737 (-)NCBI
NHGRI_mPanPan13187,827,183 - 187,995,467 (-)NCBI
Mhudiblu_PPA_v03186,976,926 - 187,141,678 (-)NCBI
PanPan1.13195,532,341 - 195,695,510 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003825012 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034333.1
RefSeq Acc Id: XP_003825012   ⟸   XM_003824964
- UniProtKB: A0A2R9BXC4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000034333   ⟸   ENSPPAT00000057214
Protein Domains
Fe2OG dioxygenase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040013 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057214.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  q2cbj1_9rhob like domain UniProtKB/TrEMBL
InterPro Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
  P3H UniProtKB/TrEMBL
  Pro_4_hyd_alph UniProtKB/TrEMBL
  Pro_4_hyd_alph_FE2OG_OXY UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene P3H2 ENTREZGENE
PANTHER PTHR14049 UniProtKB/TrEMBL
  PTHR14049:SF1 UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy_3 UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
SMART P4Hc UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A2R9BXC4 ENTREZGENE, UniProtKB/TrEMBL