ABHD3 (abhydrolase domain containing 3, phospholipase) - Rat Genome Database

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Gene: ABHD3 (abhydrolase domain containing 3, phospholipase) Pan paniscus
Analyze
Symbol: ABHD3
Name: abhydrolase domain containing 3, phospholipase
RGD ID: 12022180
Description: ENCODES a protein that exhibits acetylesterase activity (inferred); acylglycerol lipase activity (inferred); carboxylic ester hydrolase activity (inferred); INVOLVED IN medium-chain fatty acid biosynthetic process (inferred); medium-chain fatty acid catabolic process (inferred); phosphatidylcholine metabolic process (inferred); ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Niemann-Pick disease type C1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: abhydrolase domain containing 3; phospholipase ABHD3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21739,049,242 - 39,123,372 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11824,741,836 - 24,815,967 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01814,888,915 - 14,944,295 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11818,526,670 - 18,578,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1818,527,364 - 18,578,736 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ABHD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21739,049,242 - 39,123,372 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11824,741,836 - 24,815,967 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01814,888,915 - 14,944,295 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11818,526,670 - 18,578,874 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1818,527,364 - 18,578,736 (-)Ensemblpanpan1.1panPan2
ABHD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381821,650,901 - 21,704,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1821,650,901 - 21,704,780 (-)EnsemblGRCh38hg38GRCh38
GRCh371819,230,862 - 19,284,735 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361817,484,856 - 17,538,724 (-)NCBINCBI36Build 36hg18NCBI36
Build 341817,484,855 - 17,538,724NCBI
Celera1816,036,856 - 16,090,764 (-)NCBICelera
Cytogenetic Map18q11.2NCBI
HuRef1816,077,990 - 16,131,762 (-)NCBIHuRef
CHM1_11819,157,962 - 19,211,880 (-)NCBICHM1_1
T2T-CHM13v2.01821,835,996 - 21,889,881 (-)NCBIT2T-CHM13v2.0
Abhd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391810,644,411 - 10,706,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1810,642,092 - 10,706,771 (-)EnsemblGRCm39 Ensembl
GRCm381810,644,411 - 10,706,783 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1810,642,092 - 10,706,771 (-)EnsemblGRCm38mm10GRCm38
MGSCv371810,644,409 - 10,706,694 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361810,644,409 - 10,706,694 (-)NCBIMGSCv36mm8
Celera1810,674,408 - 10,736,690 (-)NCBICelera
Cytogenetic Map18A1NCBI
cM Map185.28NCBI
Abhd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8181,996,010 - 2,051,311 (-)NCBIGRCr8
mRatBN7.2181,723,203 - 1,778,488 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl181,720,718 - 1,803,428 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx181,952,568 - 2,008,143 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0182,740,264 - 2,795,850 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0181,954,460 - 2,010,020 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,892,413 - 1,946,840 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,892,413 - 1,946,840 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,925,174 - 1,979,805 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,027,477 - 2,082,082 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1182,027,474 - 2,106,019 (-)NCBI
Celera181,603,943 - 1,659,266 (-)NCBICelera
Cytogenetic Map18p13NCBI
Abhd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540210,316,297 - 10,356,052 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540210,316,881 - 10,355,760 (-)NCBIChiLan1.0ChiLan1.0
ABHD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1766,331,687 - 66,383,443 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl766,332,410 - 66,382,942 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha765,785,702 - 65,837,429 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0766,395,969 - 66,447,789 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl766,397,119 - 66,447,792 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1766,061,627 - 66,113,117 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0766,084,767 - 66,136,553 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0766,385,056 - 66,437,451 (+)NCBIUU_Cfam_GSD_1.0
Abhd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494462,408,000 - 62,451,161 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365501,359,606 - 1,407,925 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365501,359,570 - 1,408,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ABHD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6106,851,627 - 106,917,531 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16106,851,625 - 106,917,720 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2699,355,413 - 99,401,087 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ABHD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11858,795,497 - 58,842,714 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1858,795,865 - 58,842,824 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605033,573,847 - 33,619,867 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Abhd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477010,073,444 - 10,113,235 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477010,073,462 - 10,126,062 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000029012   ⟹   ENSPPAP00000007032
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1818,527,364 - 18,578,736 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029017   ⟹   ENSPPAP00000007034
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1818,527,364 - 18,578,736 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029019   ⟹   ENSPPAP00000007036
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1818,527,364 - 18,538,416 (-)Ensembl
RefSeq Acc Id: XM_008968598   ⟹   XP_008966846
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21739,049,242 - 39,123,331 (-)NCBI
NHGRI_mPanPan11824,741,836 - 24,815,967 (-)NCBI
Mhudiblu_PPA_v01814,889,971 - 14,944,295 (-)NCBI
PanPan1.11818,526,670 - 18,578,874 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034943474   ⟹   XP_034799365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21739,049,242 - 39,123,372 (-)NCBI
NHGRI_mPanPan11824,741,836 - 24,815,926 (-)NCBI
Mhudiblu_PPA_v01814,888,915 - 14,944,295 (-)NCBI
RefSeq Acc Id: XM_034943475   ⟹   XP_034799366
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21739,049,242 - 39,082,345 (-)NCBI
NHGRI_mPanPan11824,741,836 - 24,774,939 (-)NCBI
Mhudiblu_PPA_v01814,889,971 - 14,903,305 (-)NCBI
Protein Sequences
Protein RefSeqs XP_008966846 (Get FASTA)   NCBI Sequence Viewer  
  XP_034799365 (Get FASTA)   NCBI Sequence Viewer  
  XP_034799366 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000007032.1
  ENSPPAP00000007034.1
  ENSPPAP00000007036.1
Reference Protein Sequences
RefSeq Acc Id: XP_008966846   ⟸   XM_008968598
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZR75 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034799365   ⟸   XM_034943474
- Peptide Label: isoform X2
- UniProtKB: A0A2R8ZVW0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034799366   ⟸   XM_034943475
- Peptide Label: isoform X3
- UniProtKB: A0A2R8ZQ18 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000007034   ⟸   ENSPPAT00000029017
RefSeq Acc Id: ENSPPAP00000007036   ⟸   ENSPPAT00000029019
RefSeq Acc Id: ENSPPAP00000007032   ⟸   ENSPPAT00000029012
Protein Domains
AB hydrolase-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026090 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029012.1 UniProtKB/TrEMBL
  ENSPPAT00000029017.1 UniProtKB/TrEMBL
  ENSPPAT00000029019.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  AB_hydrolase_4_CS UniProtKB/TrEMBL
  ABHD4 UniProtKB/TrEMBL
NCBI Gene ABHD3 ENTREZGENE
PANTHER ABHYDROLASE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PHOSPHOLIPASE ABHD3 UniProtKB/TrEMBL
Pfam Abhydrolase_1 UniProtKB/TrEMBL
PIRSF Ab_hydro_YheT UniProtKB/TrEMBL
PROSITE UPF0017 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R8ZQ18 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZR75 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZVW0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-01-28 ABHD3  abhydrolase domain containing 3, phospholipase  ABHD3  abhydrolase domain containing 3  Symbol and/or name change 5135510 APPROVED