MPND (MPN domain containing) - Rat Genome Database

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Gene: MPND (MPN domain containing) Pan paniscus
Analyze
Symbol: MPND
Name: MPN domain containing
RGD ID: 12019151
Description: ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metal-dependent deubiquitinase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH amenorrhea (ortholog); COVID-19 (ortholog); genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,727,140 - 8,757,998 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,956,543 - 7,987,160 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,362,867 - 3,382,984 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,312,351 - 4,329,465 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,313,178 - 4,329,382 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MPND
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,727,140 - 8,757,998 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1197,956,543 - 7,987,160 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,362,867 - 3,382,984 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,312,351 - 4,329,465 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl194,313,178 - 4,329,382 (+)Ensemblpanpan1.1panPan2
MPND
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,343,562 - 4,360,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,343,527 - 4,360,086 (+)EnsemblGRCh38hg38GRCh38
GRCh37194,343,559 - 4,360,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,294,570 - 4,311,075 (+)NCBINCBI36Build 36hg18NCBI36
Celera194,281,776 - 4,298,329 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,105,998 - 4,122,602 (+)NCBIHuRef
CHM1_1194,343,227 - 4,359,729 (+)NCBICHM1_1
T2T-CHM13v2.0194,327,019 - 4,343,527 (+)NCBIT2T-CHM13v2.0
Mpnd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,316,201 - 56,323,790 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,312,711 - 56,323,790 (+)EnsemblGRCm39 Ensembl
GRCm381756,009,201 - 56,016,790 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,005,711 - 56,016,790 (+)EnsemblGRCm38mm10GRCm38
MGSCv371756,148,624 - 56,156,213 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,602,619 - 55,609,955 (+)NCBIMGSCv36mm8
Celera1759,427,863 - 59,435,452 (+)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.11NCBI
Mpnd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89926,714 - 933,620 (+)NCBIGRCr8
mRatBN7.29839,473 - 846,446 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9840,143 - 846,439 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,287,342 - 1,293,596 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,633,888 - 6,640,137 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,592,377 - 5,598,632 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0911,055,370 - 11,061,611 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl911,055,371 - 11,061,611 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0910,040,659 - 10,047,589 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,660,577 - 7,666,824 (-)NCBICelera
Cytogenetic Map9q11NCBI
Mpnd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,531,895 - 4,538,030 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,531,895 - 4,538,030 (-)NCBIChiLan1.0ChiLan1.0
MPND
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,311,890 - 55,320,226 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,304,529 - 55,320,196 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,032,429 - 55,048,360 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,963,333 - 55,979,259 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,970,987 - 55,979,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,031,495 - 55,039,433 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,504,806 - 55,520,722 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,703,487 - 55,719,409 (-)NCBIUU_Cfam_GSD_1.0
Mpnd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,330,707 - 215,338,277 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,496,506 - 2,503,959 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,491,059 - 2,504,076 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MPND
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,445,662 - 74,455,881 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,445,660 - 74,455,928 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2274,938,611 - 74,948,868 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MPND
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,072,007 - 4,090,524 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660814,112,744 - 4,132,173 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mpnd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,328,783 - 5,337,946 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,330,536 - 5,337,973 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000040937   ⟹   ENSPPAP00000018208
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl194,313,178 - 4,329,382 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040941   ⟹   ENSPPAP00000018212
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl194,313,178 - 4,329,382 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000040946   ⟹   ENSPPAP00000018217
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl194,313,178 - 4,329,382 (+)Ensembl
RefSeq Acc Id: XM_034945477   ⟹   XP_034801368
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,727,140 - 8,757,998 (+)NCBI
NHGRI_mPanPan1197,956,543 - 7,987,160 (+)NCBI
Mhudiblu_PPA_v0193,362,867 - 3,382,984 (+)NCBI
RefSeq Acc Id: XM_034945478   ⟹   XP_034801369
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,737,765 - 8,757,998 (+)NCBI
NHGRI_mPanPan1197,967,262 - 7,987,160 (+)NCBI
Mhudiblu_PPA_v0193,362,867 - 3,382,984 (+)NCBI
RefSeq Acc Id: XM_034945479   ⟹   XP_034801370
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2208,741,407 - 8,757,998 (+)NCBI
NHGRI_mPanPan1197,970,825 - 7,987,160 (+)NCBI
Mhudiblu_PPA_v0193,366,433 - 3,382,984 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034801368 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801369 (Get FASTA)   NCBI Sequence Viewer  
  XP_034801370 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000018208.1
  ENSPPAP00000018212.1
  ENSPPAP00000018217.1
Reference Protein Sequences
RefSeq Acc Id: XP_034801368   ⟸   XM_034945477
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034801369   ⟸   XM_034945478
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034801370   ⟸   XM_034945479
- Peptide Label: isoform X3
RefSeq Acc Id: ENSPPAP00000018208   ⟸   ENSPPAT00000040937
RefSeq Acc Id: ENSPPAP00000018212   ⟸   ENSPPAT00000040941
RefSeq Acc Id: ENSPPAP00000018217   ⟸   ENSPPAT00000040946
Protein Domains
MPN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032201 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040937.1 UniProtKB/TrEMBL
  ENSPPAT00000040941.1 UniProtKB/TrEMBL
  ENSPPAT00000040946.1 UniProtKB/TrEMBL
Gene3D-CATH Cytidine Deaminase, domain 2 UniProtKB/TrEMBL
InterPro JAB_dom_prok UniProtKB/TrEMBL
  JAMM/MPN+_dom UniProtKB/TrEMBL
  MPN UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
NCBI Gene MPND ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UniProtKB/TrEMBL
  MPN DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam JAB UniProtKB/TrEMBL
  Prok-JAB UniProtKB/TrEMBL
  RAMA UniProtKB/TrEMBL
PROSITE MPN UniProtKB/TrEMBL
Superfamily-SCOP JAB1/MPN domain UniProtKB/TrEMBL
UniProt A0A2R9ALI5_PANPA UniProtKB/TrEMBL
  A0A2R9ALJ0_PANPA UniProtKB/TrEMBL
  A0A2R9AM26_PANPA UniProtKB/TrEMBL