ATP8A2 (ATPase phospholipid transporting 8A2) - Rat Genome Database

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Gene: ATP8A2 (ATPase phospholipid transporting 8A2) Pan paniscus
Analyze
Symbol: ATP8A2
Name: ATPase phospholipid transporting 8A2
RGD ID: 12013309
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATPase-coupled intramembrane lipid transporter activity (inferred); INVOLVED IN neuron projection development (ortholog); ASSOCIATED WITH cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome (ortholog); cerebellar ataxia, impaired intellectual development, and dysequilibrium syndrome 4 (ortholog); epilepsy (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phospholipid-transporting ATPase IB
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21424,968,362 - 25,625,553 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11316,078,416 - 16,733,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,663,888 - 7,319,094 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11325,111,454 - 25,668,526 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1325,111,653 - 25,662,668 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ATP8A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21424,968,362 - 25,625,553 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11316,078,416 - 16,733,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,663,888 - 7,319,094 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11325,111,454 - 25,668,526 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1325,111,653 - 25,662,668 (+)Ensemblpanpan1.1panPan2
ATP8A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381325,371,974 - 26,025,851 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1325,371,974 - 26,025,851 (+)EnsemblGRCh38hg38GRCh38
GRCh371325,946,112 - 26,599,989 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,844,209 - 25,493,420 (+)NCBINCBI36Build 36hg18NCBI36
Build 341324,941,114 - 25,492,996NCBI
Celera137,010,413 - 7,663,625 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef136,857,229 - 7,413,507 (+)NCBIHuRef
CHM1_11325,914,386 - 26,563,571 (+)NCBICHM1_1
T2T-CHM13v2.01324,581,610 - 25,239,722 (+)NCBIT2T-CHM13v2.0
Gm57492
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391460,423,607 - 60,434,657 (-)NCBIGRCm39GRCm39mm39
GRCm381460,186,158 - 60,197,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1459,638,540 - 60,197,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv371460,266,578 - 60,705,671 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361458,601,851 - 59,040,944 (-)NCBIMGSCv36mm8
Celera1457,450,161 - 57,876,764 (-)NCBICelera
Cytogenetic Map14D1NCBI
Atp8a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81537,993,507 - 38,526,408 (-)NCBIGRCr8
mRatBN7.21533,817,309 - 34,350,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1533,819,755 - 34,350,223 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01539,955,689 - 40,488,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1540,000,322 - 40,428,800 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01543,781,312 - 44,300,886 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41538,759,902 - 39,271,237 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1533,526,116 - 34,051,833 (-)NCBICelera
Cytogenetic Map15p12NCBI
ATP8A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12513,490,550 - 14,066,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2513,495,970 - 14,066,513 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2513,563,109 - 14,143,498 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02513,628,570 - 14,196,913 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2513,628,575 - 14,196,698 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12513,511,708 - 14,079,496 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02513,507,713 - 14,081,688 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02513,555,345 - 14,129,847 (-)NCBIUU_Cfam_GSD_1.0
LOC101972040
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945115,687,558 - 116,313,133 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936688305,742 - 925,223 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936688299,831 - 925,444 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523747
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,277,951 - 3,793,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1113,277,395 - 3,793,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,576,600 - 2,969,328 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP8A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.134,747,744 - 5,378,598 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl34,747,882 - 5,323,235 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605739,047,880 - 39,695,138 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp8a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477612,480,291 - 13,061,478 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477612,474,442 - 13,126,237 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000035042   ⟹   ENSPPAP00000012377
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1325,111,653 - 25,662,668 (+)Ensembl
RefSeq Acc Id: XM_008971630   ⟹   XP_008969878
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21425,064,991 - 25,625,553 (+)NCBI
NHGRI_mPanPan11316,175,050 - 16,733,655 (+)NCBI
Mhudiblu_PPA_v0136,760,535 - 7,318,394 (+)NCBI
PanPan1.11325,111,454 - 25,668,526 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008971631   ⟹   XP_008969879
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21425,083,790 - 25,625,553 (+)NCBI
NHGRI_mPanPan11316,193,852 - 16,733,655 (+)NCBI
Mhudiblu_PPA_v0136,779,321 - 7,319,094 (+)NCBI
PanPan1.11325,130,277 - 25,668,526 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034936476   ⟹   XP_034792367
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21424,968,362 - 25,625,553 (+)NCBI
NHGRI_mPanPan11316,078,416 - 16,733,655 (+)NCBI
Mhudiblu_PPA_v0136,663,888 - 7,318,388 (+)NCBI
RefSeq Acc Id: XM_055096569   ⟹   XP_054952544
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21424,968,449 - 25,625,553 (+)NCBI
NHGRI_mPanPan11316,078,498 - 16,733,655 (+)NCBI
Protein Sequences
Protein RefSeqs XP_008969878 (Get FASTA)   NCBI Sequence Viewer  
  XP_008969879 (Get FASTA)   NCBI Sequence Viewer  
  XP_034792367 (Get FASTA)   NCBI Sequence Viewer  
  XP_054952544 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012377.1
RefSeq Acc Id: XP_008969878   ⟸   XM_008971630
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AAA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008969879   ⟸   XM_008971631
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AAA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034792367   ⟸   XM_034936476
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AAA6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000012377   ⟸   ENSPPAT00000035042
RefSeq Acc Id: XP_054952544   ⟸   XM_055096569
- Peptide Label: isoform X3
Protein Domains
P-type ATPase C-terminal   P-type ATPase N-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029372 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035042.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1110.10 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
  Calcium-transporting ATPase, cytoplasmic transduction domain A UniProtKB/TrEMBL
InterPro ATPase_P-typ_cyto_dom_N UniProtKB/TrEMBL
  ATPase_P-typ_P_site UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom_sf UniProtKB/TrEMBL
  ATPase_P-typ_transduc_dom_A_sf UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  P-type_ATPase_IV UniProtKB/TrEMBL
  P-type_ATPase_N UniProtKB/TrEMBL
  P_typ_ATPase UniProtKB/TrEMBL
  P_typ_ATPase_c UniProtKB/TrEMBL
  P_typ_ATPase_HD_dom UniProtKB/TrEMBL
NCBI Gene ATP8A2 ENTREZGENE
PANTHER PHOSPHOLIPID-TRANSPORTING ATPASE IB UniProtKB/TrEMBL
  PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE UniProtKB/TrEMBL
Pfam Cation_ATPase UniProtKB/TrEMBL
  E1-E2_ATPase UniProtKB/TrEMBL
  PhoLip_ATPase_C UniProtKB/TrEMBL
  PhoLip_ATPase_N UniProtKB/TrEMBL
PRINTS CATATPASE UniProtKB/TrEMBL
PROSITE ATPASE_E1_E2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
  SSF81653 UniProtKB/TrEMBL
  SSF81660 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
UniProt A0A2R9AAA6 ENTREZGENE, UniProtKB/TrEMBL