MIR198 (microRNA mir-198) - Rat Genome Database

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Gene: MIR198 (microRNA mir-198) Pan paniscus
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Symbol: MIR198
Name: microRNA mir-198
RGD ID: 11969335
Description: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Type: ncrna
RefSeq Status: PROVISIONAL
Previously known as: microRNA 198; ppa-mir-198
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22118,365,003 - 118,365,064 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13118,369,781 - 118,369,842 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03117,510,220 - 117,510,281 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13124,421,675 - 124,421,736 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
RISC complex  (IEA)

References
Additional References at PubMed
PMID:15652478   PMID:16381832  


Genomics


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NR_106587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: NR_106587
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22118,365,003 - 118,365,064 (-)NCBI
NHGRI_mPanPan13118,369,781 - 118,369,842 (-)NCBI
Mhudiblu_PPA_v03117,510,220 - 117,510,281 (-)NCBI
PanPan1.13124,421,675 - 124,421,736 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
miRBase MI0002916 ENTREZGENE
NCBI Gene MIR198 ENTREZGENE
RNAcentral URS000001B1C8 RNACentral
  URS000021862C RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-04-02 MIR198  microRNA mir-198    microRNA 198  Symbol and/or name change 5135510 APPROVED