FEM1C (fem-1 homolog C) - Rat Genome Database

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Gene: FEM1C (fem-1 homolog C) Pan paniscus
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Symbol: FEM1C
Name: fem-1 homolog C
RGD ID: 11940714
Description: ENCODES a protein that exhibits ubiquitin-like ligase-substrate adaptor activity (inferred); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (inferred); ASSOCIATED WITH autistic disorder (ortholog); familial adenomatous polyposis 1 (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24110,769,034 - 110,823,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15108,922,695 - 108,977,054 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05110,878,460 - 110,902,650 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,675,163 - 116,699,085 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5116,675,163 - 116,699,085 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FEM1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24110,769,034 - 110,823,393 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15108,922,695 - 108,977,054 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05110,878,460 - 110,902,650 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15116,675,163 - 116,699,085 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5116,675,163 - 116,699,085 (-)Ensemblpanpan1.1panPan2
FEM1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385115,520,908 - 115,544,775 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5115,520,908 - 115,544,775 (-)EnsemblGRCh38hg38GRCh38
GRCh375114,856,605 - 114,880,472 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365114,884,507 - 114,908,490 (-)NCBINCBI36Build 36hg18NCBI36
Build 345114,884,506 - 114,908,490NCBI
Celera5110,805,894 - 110,829,879 (-)NCBICelera
Cytogenetic Map5q22.3NCBI
HuRef5110,038,231 - 110,062,214 (-)NCBIHuRef
CHM1_15114,289,245 - 114,313,228 (-)NCBICHM1_1
T2T-CHM13v2.05116,033,707 - 116,057,577 (-)NCBIT2T-CHM13v2.0
Fem1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391846,637,673 - 46,659,038 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1846,634,813 - 46,659,038 (-)EnsemblGRCm39 Ensembl
GRCm381846,504,606 - 46,525,971 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1846,501,746 - 46,525,971 (-)EnsemblGRCm38mm10GRCm38
MGSCv371846,664,260 - 46,685,625 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361846,629,937 - 46,651,302 (-)NCBIMGSCv36mm8
Celera1847,864,874 - 47,886,277 (-)NCBICelera
Cytogenetic Map18CNCBI
cM Map1824.62NCBI
Fem1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81841,419,511 - 41,445,300 (-)NCBIGRCr8
mRatBN7.21839,232,900 - 39,258,692 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1839,232,900 - 39,258,692 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1841,266,128 - 41,291,917 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01841,968,370 - 41,994,160 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01839,761,485 - 39,787,275 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01840,493,156 - 40,518,988 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1840,493,156 - 40,518,988 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01840,147,977 - 40,173,809 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41840,710,247 - 40,740,448 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11840,754,604 - 40,777,989 (-)NCBI
Celera1837,484,817 - 37,510,604 (-)NCBICelera
Cytogenetic Map18q11NCBI
Fem1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540835,291,685 - 35,316,330 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540835,291,791 - 35,315,628 (-)NCBIChiLan1.0ChiLan1.0
FEM1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1115,248,564 - 5,271,370 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl115,180,798 - 5,271,891 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha115,397,620 - 5,422,864 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0115,239,025 - 5,264,290 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl115,239,028 - 5,264,277 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1115,194,370 - 5,219,592 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0115,263,388 - 5,288,834 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0115,517,087 - 5,542,313 (-)NCBIUU_Cfam_GSD_1.0
Fem1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213127,977,400 - 128,005,204 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936742677,746 - 705,350 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936742678,171 - 706,019 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEM1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2119,699,598 - 119,722,806 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12119,699,594 - 119,723,040 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22124,598,704 - 124,600,560 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FEM1C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12318,773,359 - 18,797,316 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2318,771,956 - 18,797,128 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603459,600,709 - 59,624,705 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fem1c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247336,380,506 - 6,413,006 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000056033   ⟹   ENSPPAP00000033163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5116,675,163 - 116,699,085 (-)Ensembl
RefSeq Acc Id: XM_003826724   ⟹   XP_003826772
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24110,769,034 - 110,793,275 (-)NCBI
NHGRI_mPanPan15108,922,695 - 108,946,936 (-)NCBI
Mhudiblu_PPA_v05110,878,460 - 110,902,650 (-)NCBI
PanPan1.15116,675,163 - 116,699,085 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055112555   ⟹   XP_054968530
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24110,769,034 - 110,823,393 (-)NCBI
NHGRI_mPanPan15108,922,695 - 108,977,054 (-)NCBI
RefSeq Acc Id: XM_055112556   ⟹   XP_054968531
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24110,769,034 - 110,823,390 (-)NCBI
NHGRI_mPanPan15108,922,695 - 108,977,051 (-)NCBI
RefSeq Acc Id: XM_055112559   ⟹   XP_054968534
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24110,769,034 - 110,823,384 (-)NCBI
NHGRI_mPanPan15108,922,695 - 108,977,045 (-)NCBI
RefSeq Acc Id: XM_055112560   ⟹   XP_054968535
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24110,769,034 - 110,823,390 (-)NCBI
NHGRI_mPanPan15108,922,695 - 108,977,051 (-)NCBI
RefSeq Acc Id: XP_003826772   ⟸   XM_003826724
- UniProtKB: A0A2R9BU13 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000033163   ⟸   ENSPPAT00000056033
RefSeq Acc Id: XP_054968530   ⟸   XM_055112555
- UniProtKB: A0A2R9BU13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054968531   ⟸   XM_055112556
- UniProtKB: A0A2R9BU13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054968535   ⟸   XM_055112560
- UniProtKB: A0A2R9BU13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054968534   ⟸   XM_055112559
- UniProtKB: A0A2R9BU13 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039455 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056033.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  1.25.40.20 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  CRL2_E3_Ligase_Fem-1 UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100987846 UniProtKB/TrEMBL
NCBI Gene FEM1C ENTREZGENE
PANTHER ANKYRIN REPEAT CONTAINING UniProtKB/TrEMBL
  ANKYRIN REPEAT DOMAIN 16 UniProtKB/TrEMBL
Pfam Ank UniProtKB/TrEMBL
  Ank_2 UniProtKB/TrEMBL
PRINTS ANKYRIN UniProtKB/TrEMBL
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP SSF48403 UniProtKB/TrEMBL
UniProt A0A2R9BU13 ENTREZGENE, UniProtKB/TrEMBL