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Gene: RIOK3 (RIO kinase 3) Pan paniscus

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Symbol:

RIOK3

Name:

RIO kinase 3

RGD ID:

11914437

Description:

ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase activity (inferred); AMP-activated protein kinase activity (inferred); ATP binding (inferred); INVOLVED IN cellular response to dsDNA (inferred); cellular response to dsRNA (inferred); cellular response to virus (inferred); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH genetic disease (ortholog); intellectual disability (ortholog); Niemann-Pick disease type C1 (ortholog); FOUND IN preribosome, small subunit precursor (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine-protein kinase RIO3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RIOK3 (RIO kinase 3)	NCBI	Ortholog
Mus musculus (house mouse):	Riok3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Riok3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Riok3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RIOK3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Riok3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RIOK3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RIOK3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Riok3 (RIO kinase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	40,883,197 - 40,913,567 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	26,575,892 - 26,606,159 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	16,703,893 - 16,734,160 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	20,331,222 - 20,360,825 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	20,331,222 - 20,360,825 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

intellectual disability (ISO)

Niemann-Pick disease type C1 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to dsDNA (IEA)

cellular response to dsRNA (IEA)

cellular response to virus (IEA)

chromatin remodeling (IEA)

innate immune response (IEA)

maturation of SSU-rRNA (IEA)

negative regulation of canonical NF-kappaB signal transduction (IEA)

negative regulation of MDA-5 signaling pathway (IEA)

negative regulation of protein-containing complex assembly (IEA)

positive regulation of innate immune response (IEA)

positive regulation of interferon-beta production (IEA)

ribosome biogenesis (IEA)

Cellular Component

preribosome, small subunit precursor (IEA)

Molecular Function

3-phosphoinositide-dependent protein kinase activity (IEA)

AMP-activated protein kinase activity (IEA)

ATP binding (IEA)

caspase binding (IEA)

DNA-dependent protein kinase activity (IEA)

eukaryotic translation initiation factor 2alpha kinase activity (IEA)

histone H2AS1 kinase activity (IEA)

histone H2AS121 kinase activity (IEA)

histone H2AT120 kinase activity (IEA)

histone H2AXS139 kinase activity (IEA)

histone H2BS14 kinase activity (IEA)

histone H2BS36 kinase activity (IEA)

histone H3S10 kinase activity (IEA)

histone H3S28 kinase activity (IEA)

histone H3S57 kinase activity (IEA)

histone H3T11 kinase activity (IEA)

histone H3T3 kinase activity (IEA)

histone H3T45 kinase activity (IEA)

histone H3T6 kinase activity (IEA)

histone H4S1 kinase activity (IEA)

metal ion binding (IEA)

protein binding (ISO)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

Rho-dependent protein serine/threonine kinase activity (IEA)

ribosomal protein S6 kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

ribosome biogenesis pathway (ISO)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

RIOK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	40,883,197 - 40,913,567 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	26,575,892 - 26,606,159 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	16,703,893 - 16,734,160 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	20,331,222 - 20,360,825 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	18	20,331,222 - 20,360,825 (+)	Ensembl	panpan1.1		panPan2

RIOK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	23,453,287 - 23,483,140 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	23,453,287 - 23,486,603 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	21,033,251 - 21,063,104 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	19,286,785 - 19,317,099 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	18	17,848,659 - 17,878,896 (+)	NCBI		Celera
Cytogenetic Map	18	q11.2	NCBI
HuRef	18	17,887,418 - 17,918,056 (+)	NCBI		HuRef
CHM1_1	18	20,960,091 - 20,990,377 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	23,647,357 - 23,677,204 (+)	NCBI		T2T-CHM13v2.0

Riok3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	12,259,114 - 12,290,424 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	12,261,798 - 12,290,444 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	12,126,091 - 12,157,367 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	12,128,741 - 12,157,387 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	12,287,359 - 12,315,876 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	12,272,295 - 12,300,233 (+)	NCBI		MGSCv36	mm8
Celera	18	12,362,375 - 12,390,919 (+)	NCBI		Celera
Cytogenetic Map	18	A1	NCBI
cM Map	18	6.15	NCBI

Riok3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	3,602,535 - 3,628,108 (+)	NCBI		GRCr8
mRatBN7.2	18	3,327,776 - 3,353,350 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	3,327,776 - 3,353,343 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	3,557,542 - 3,583,176 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	4,345,238 - 4,370,872 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	3,585,937 - 3,611,506 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	3,565,166 - 3,590,739 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	3,565,166 - 3,590,739 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	3,574,641 - 3,600,214 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	3,672,960 - 3,698,533 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	3,671,525 - 3,697,561 (+)	NCBI
Celera	18	3,188,163 - 3,213,735 (+)	NCBI		Celera
Cytogenetic Map	18	p13	NCBI

Riok3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	11,648,849 - 11,672,545 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	11,649,160 - 11,670,010 (+)	NCBI	ChiLan1.0	ChiLan1.0

RIOK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	64,835,810 - 64,860,464 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	64,837,233 - 64,860,393 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	64,289,376 - 64,314,116 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	64,900,222 - 64,924,918 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	64,900,021 - 64,924,902 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	64,567,845 - 64,592,544 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	64,583,689 - 64,608,375 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	64,888,165 - 64,912,877 (-)	NCBI		UU_Cfam_GSD_1.0

Riok3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	60,866,792 - 60,894,814 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936550	2,921,227 - 2,950,164 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936550	2,921,272 - 2,949,288 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RIOK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	108,339,013 - 108,363,868 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	108,338,986 - 108,363,872 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	100,883,279 - 100,896,844 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RIOK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	57,048,500 - 57,078,770 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	57,048,447 - 57,078,312 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	31,799,631 - 31,829,433 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Riok3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624770	8,675,294 - 8,697,620 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624770	8,675,501 - 8,696,999 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008955753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008955754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034943446	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000036955 ⟹ ENSPPAP00000014275

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	18	20,331,222 - 20,360,825 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000036967 ⟹ ENSPPAP00000014286

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	18	20,331,438 - 20,358,973 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000036970 ⟹ ENSPPAP00000014289

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	18	20,339,372 - 20,354,902 (+)	Ensembl

RefSeq Acc Id:

XM_008955753 ⟹ XP_008954001

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	17	40,883,197 - 40,913,567 (+)	NCBI
NHGRI_mPanPan1	18	26,575,892 - 26,606,159 (+)	NCBI
Mhudiblu_PPA_v0	18	16,703,893 - 16,734,160 (+)	NCBI
PanPan1.1	18	20,331,222 - 20,360,825 (+)	NCBI

Sequence:

show sequence

AACAACAACAACCACAAACTCCGACCGTCCTTTCCAGGCCCTTTCCCTCTATAAACCTGCCGTT
TTCTGTCTCCCAAGTCATCCCAGTTTAGAACTGCTCCAGGAAATAATGAATGAACAGAGAGAGC
CTAGTTTGTTTATTTATTTACAATCCACCAGTCTAATCTAGTTTAGATCCAGCGGCAATTTTTG
GGGTGCCAAGGAGGAAAGAAGGAGATGGCAGTGCGGGGACAGGGCAGAGCCTGGGCCAAAGGAA
GCCACACCCAGTTCTTGCCCTGCCCTGCCCGACACAGGCAACGTGACCCCAAGCGACAGCCAGC
TGATGCTTGCTTCTCCGAGCCCGGCGGTCAGCGGCCGGAAGTAGCCCGCCCGGGGGCGGGGAAA
GGTGCCTTAAGGAGGAGCTAGGGGCGTGCGGCCAATTGCAAGCGACTGTCCTAGCGAAGAGGGC
GGAAGAGGAGAGATCCAGTTCCGGACGCGGCCGCCGCCGTCGCCGCCATCTGTCACCTGCGCTC
CGACATCAGCAGCTAGTCGCCCGTGTCCCGCCTGTCTCCTCGGCGGAGCCTGCTGCCCGTCCTG
CCACCTCTCTGCTCTGTTCTTGTCTCTGCCTTCATCCCCGAATGGATCTGGTAGGAGTGGCATC
GCCTGAGCCCGGGACGGCAGCGGCCTGGGGACCCAGCAAGTGTCCATGGGCTATTCCTCAAAAT
ACAATATCTTGTTCTTTGGCTGATGTAATGAGTGAACAGCTGGCCAAAGAATTGCAGTTAGAAG
AAGAAGCTGCCGTTTTTCCTGAAGTTGCTGTTGCTGAAGGACCATTTATTACTGGAGAAAACAT
TGATACTTCCAGTGACCTTATGCTGGCTCAGATGCTACAGATGGAATATGACAGAGAATATGAT
GCACAGCTTAGGCGTGAAGAAAAAAAATTCAATGGAGATAGCAAAGTTTCCATTTCCTTTGAAA
ATTATCGAAAAGTGCATCCTTATGAAGACAGCGATAGCTCTGAAGATGAGGTTGACTGGCAGGA
TACTCGTGATGATCCCTACAGACCAGCAAAACCGGTTCCCACTCCTAAAAAGGGCTTTATTGGA
AAAGGAAAAGATATCACCACCAAACATGATGAAGTAGTATGTGGGAGAAAGAACACAGCAAGAA
TGGAAAATTTTGCACCTGAGTTTCAGGTAGGAGATGGAATTGGAATGGATTTAAAACTATCAAA
CCATGTTTTCAATGCTTTAAAACAACATGCCTACTCAGAAGAACGTCGAAGTGCCCGCCTACAT
GAGAAAAAGGAGCATTCTACAGCAGAAAAAGCAGTTGATCCTAAGACACGTTTACTTATGTATA
AAATGGTCAACTCTGGAATGTTGGAGACAATCACTGGCTGTATTAGTACAGGAAAGGAGTCTGT
TGTCTTTCATGCATATGGAGGGAGCATGGAGGATGAAAAGGAAGATAGTAAAGTTATACCTACA
GAATGTGCCATCAAGGTATTTAAAACAACCCTTAATGAGTTTAAGAATCGTGACAAATATATTA
AAGATGATTTCAGGTTTAAAGATCGCTTCAGTAAACTAAATCCACGTAAGATCATCCGCATGTG
GGCAGAAAAAGAAATGCACAATCTCGCAAGAATGCAGAGAGCTGGAATTCCTTGTCCAACAGTT
GTACTACTGAAGAAACACATTTTAGTTATGTCTTTTATTGGCCATGATCAAGTTCCAGCCCCTA
AATTAAAAGAAGTAAAGCTCAATAGTGAAGAAATGAAAGAAGCCTACTATCAAACTCTTCATTT
GATGCAGCAGTTATATCATGAATGTACGCTTGTCCATGCTGACCTCAGTGAGTATAACATGCTG
TGGCATGCTGGAAAGGTCTGGTTGATTGATGTCAGTCAGTCAGTAGAACCTACCCACCCTCACG
GCCTGGAGTTCTTGTTCCGGGACTGCAGGAATGTCTCGCAGTTTTTCCAGAAAGGAGGAGTCAA
AGAAGCCCTTAGTGAACGAGAACTCTTCAATGCTGTTTCAGGCTTAAACATCACAGCAGATAAT
GAAGCTGATTTTTTAGCTGAGATAGAAGCTTTGGAGAAAATGAATGAAGATCACGTTCAGAAGA
ATGGAAGGAAAGCTGCTTCATTTTTGAAAGATGATGGAGACCCACCACTACTATATGATGAATA
GCACTAATATCCACTGCTTCAGTTTTAACACAGCAGTGATTGTCAGCTGCCAATAGCAAATGAA
GTTATGGGTGACTTGAAATACCAAAACATGAGGAGTGGGCAATGGTGCTTCTGTGCTTTTCCCC
CTTGTAACCCATGTGCCAGATGTGTGGAATTTTTAGCTCAGCATTGAGAGAATAAAATGTCACT
ACCTCTCATCTTATGAACAGGATAATATAATTCTTTAACAGCTATAGGTTATCTGGCTGAAGTA
GACCTAATTTTATGTGACTTGTGGTGTAAAATGTCTTGATGATAATTTTTAAAACTTGGGTAAC
ACTTCCAAATATGGGAGGAAAGGACAGATGTGTTTACAAGGGAGGATTTTACAACATACTTGCT
TTATTCACCTCCCTGTTTTGTGTTGCGTCTTTCCTTGAATATTTTATTGGCCCAGAGTTAGCCT
TTCTCAATTATGTTTCCAGACTGTGGCCATGATTCTAAAGGAAAATGTGTGCTCTTTAGTGGGT
AGAACAAATGGAAATTTGGTTTCAGAATGGCTGACAGAAATCGACATAAGTCATGTAATTTTTG
TTGATATATCATGAAAATGAACAGAATTCTTTTTCCATACTTACATCTAAGAAAAGGCATCATA
GGTTTCTGAGAGAGATAACTATATAACAGCTTTTTAATTATCCAATCAACTTTCAGCTTTTCTA
CATTTAGGTAAAATGGTTAGGATATAACTCATGGTGTGGCTAATCTACATTTATCAATAAAATG
TAAATTATCTGAAAGGACAGAATATAAGATTTAACCATGTTTGATGTATTTTAATTTAGTTAAT
GAAGCAAAATTCAGTTTATATTTCACTAGAACTGTGTACTTGATTGATTTTCAGAGAAATATCA
CAAATTAGAAATATTAAATCTAAGGATGAAAGGTATATATAAAACAATTTGGGGGCCAGGCACG
ATGGCTCAAACCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGAGGTCAGG
AGTTCAAGACCAGCCTTGGCAAATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCG
GGTGTGGTGGCACTTCTCTGTAATCTCAGCTTCTCAGGAGGCTGAGACAGGAGAATCGCCTGAA
CCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAG
GGGAAACTCCGTCTCCAGGAAAAAAAAAAAAACCAATTTGGATACCAAATTAATCAACTAATTT
GAGCTATCTGGCCTTACTCTTAGTAGTTTTTAGTACGTGCTGGACACCACTTTTAAAAAGCAAT
CACTGTGCTAGAAAAGTATATTGGCTTTGTTAGGATTAAAGTTCATTAACTTCAATGTAATCAT
GCCTCCTATTACTGAAGTCAGATTGGAACCACTAAAGATCCAAACTTTCTGTCTGGTAATAGAA
AGTAAAAATCTAGACATCATTTACATTTGAGAAAGCTGTTTTTAACATTATTTTAAAATGCCAA
ATATGTTCTTTCTAGAAAAATATTTGTTTTTGTTGGATAGCTTTTAATTACATTTCAGAGAGGT
GTAATTTTGGGTAGATGCTCATTACATTTTTGAAAGGTTTACTATTCCAAAATAAAGATTTAGA
TGACTGGTGATACTGGCTTTACAGAAATTTCAGAGAACTAATTTTTAAAATCTTTAGCATTTAA
AACTTTTTTTGTTTTGTTTTCTGACATATTCTGACAAAGAGCAGCAAACCACTGCTGTGTGGCA
TTCTTGGAGTGTGCTGTGAATGTGCTTTTTAAGAAATTAAAAAGAGATCATTTTAAAATTG

hide sequence

RefSeq Acc Id:

XM_034943446 ⟹ XP_034799337

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	17	40,883,197 - 40,913,567 (+)	NCBI
NHGRI_mPanPan1	18	26,575,892 - 26,606,159 (+)	NCBI
Mhudiblu_PPA_v0	18	16,703,915 - 16,732,511 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008954001	(Get FASTA)	NCBI Sequence Viewer
	XP_034799337	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000014275
	ENSPPAP00000014275.1
	ENSPPAP00000014286.1
	ENSPPAP00000014289.1

RefSeq Acc Id:	XP_008954001 ⟸ XM_008955753
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AAJ1 (UniProtKB/TrEMBL), A0A2R9ABL9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKELQLEEEAAVFPEVAVAEG PFITGENIDTSSDLMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYRKVHPYEDSDSS EDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARMENFAPEFQVGDGI GMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLLMYKMVNSGMLETITGC ISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFKNRDKYIKDDFRFKDRFSKLN PRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKE AYYQTLHLMQQLYHECTLVHADLSEYNMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQ FFQKGGVKEALSERELFNAVSGLNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGD PPLLYDE hide sequence

RefSeq Acc Id:	XP_034799337 ⟸ XM_034943446
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9ABL9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000014289 ⟸ ENSPPAT00000036970

Ensembl Acc Id:

ENSPPAP00000014286 ⟸ ENSPPAT00000036967

Ensembl Acc Id:

ENSPPAP00000014275 ⟸ ENSPPAT00000036955

Protein Domains

RIO kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000030258	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000036955.1	UniProtKB/TrEMBL
	ENSPPAT00000036967.1	UniProtKB/TrEMBL
	ENSPPAT00000036970.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	RIO-type_Ser/Thr_kinase	UniProtKB/TrEMBL
	RIO_kinase	UniProtKB/TrEMBL
	RIO_kinase_CS	UniProtKB/TrEMBL
	Ser/Thr_kinase_Rio3	UniProtKB/TrEMBL
KEGG Report	pps:100980623	UniProtKB/TrEMBL
NCBI Gene	RIOK3	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE RIO1	UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE RIO3	UniProtKB/TrEMBL
Pfam	RIO1	UniProtKB/TrEMBL
PIRSF	Ser/Thr_PK_RIO3	UniProtKB/TrEMBL
PROSITE	RIO1	UniProtKB/TrEMBL
SMART	RIO	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9AAJ1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AAJ9_PANPA	UniProtKB/TrEMBL
	A0A2R9ABL9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

RGD Manual Annotations