PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3) - Rat Genome Database

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Gene: PLCXD3 (phosphatidylinositol specific phospholipase C X domain containing 3) Pan paniscus
Analyze
Symbol: PLCXD3
Name: phosphatidylinositol specific phospholipase C X domain containing 3
RGD ID: 11907530
Description: ENCODES a protein that exhibits phosphoric diester hydrolase activity (inferred); INVOLVED IN lipid metabolic process (inferred); ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: PI-PLC X domain-containing protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2468,837,058 - 69,037,309 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1566,990,680 - 67,190,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0568,885,917 - 69,079,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1573,928,078 - 74,123,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl573,928,317 - 74,121,546 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
glutamatergic synapse  (ISO)
synapse  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLCXD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2468,837,058 - 69,037,309 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1566,990,680 - 67,190,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0568,885,917 - 69,079,834 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1573,928,078 - 74,123,570 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl573,928,317 - 74,121,546 (+)Ensemblpanpan1.1panPan2
PLCXD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38541,306,952 - 41,510,601 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl541,306,952 - 41,510,601 (-)EnsemblGRCh38hg38GRCh38
GRCh37541,307,054 - 41,510,703 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36541,342,805 - 41,546,487 (-)NCBINCBI36Build 36hg18NCBI36
Celera541,195,619 - 41,399,134 (-)NCBICelera
Cytogenetic Map5p13.1NCBI
HuRef541,259,522 - 41,463,634 (-)NCBIHuRef
CHM1_1541,309,079 - 41,512,527 (-)NCBICHM1_1
T2T-CHM13v2.0541,563,425 - 41,766,981 (-)NCBIT2T-CHM13v2.0
Plcxd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39154,404,973 - 4,605,067 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl154,404,973 - 4,605,035 (+)EnsemblGRCm39 Ensembl
GRCm38154,375,491 - 4,575,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl154,375,491 - 4,575,553 (+)EnsemblGRCm38mm10GRCm38
MGSCv37154,325,491 - 4,525,585 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36154,325,491 - 4,470,414 (+)NCBIMGSCv36mm8
Celera154,236,436 - 4,428,991 (+)NCBICelera
Cytogenetic Map15A1NCBI
cM Map151.96NCBI
Plcxd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8255,294,597 - 55,473,968 (+)NCBIGRCr8
mRatBN7.2253,567,022 - 53,746,384 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl253,567,022 - 53,746,384 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx260,693,680 - 60,858,116 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0258,752,412 - 58,916,834 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0253,745,239 - 53,922,397 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0254,191,538 - 54,360,780 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl254,191,538 - 54,360,780 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0273,220,198 - 73,389,440 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4253,401,083 - 53,584,697 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1253,329,468 - 53,512,933 (+)NCBI
Celera249,231,797 - 49,405,738 (+)NCBICelera
Cytogenetic Map2q16NCBI
Plcxd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542625,569,468 - 25,719,952 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542625,563,222 - 25,719,939 (-)NCBIChiLan1.0ChiLan1.0
PLCXD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1468,013,905 - 68,198,316 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl468,014,162 - 68,198,283 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha467,697,069 - 67,881,481 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0468,526,001 - 68,710,417 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl468,526,233 - 68,692,125 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1468,287,206 - 68,471,449 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0468,397,959 - 68,583,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0468,937,855 - 69,122,456 (+)NCBIUU_Cfam_GSD_1.0
Plcxd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213229,988,119 - 230,133,463 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365181,238,783 - 1,378,008 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365181,238,283 - 1,379,318 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCXD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1626,165,588 - 26,347,135 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11626,144,798 - 26,348,578 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21627,361,652 - 27,534,255 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLCXD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1440,082,622 - 40,268,861 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl440,082,871 - 40,269,080 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607130,514,436 - 30,704,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcxd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475913,473,653 - 13,671,795 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475913,473,863 - 13,678,067 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003810978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000030765   ⟹   ENSPPAP00000008130
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl573,928,317 - 74,121,546 (+)Ensembl
RefSeq Acc Id: XM_003810978   ⟹   XP_003811026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2468,837,058 - 69,037,309 (+)NCBI
NHGRI_mPanPan1566,990,680 - 67,190,940 (+)NCBI
Mhudiblu_PPA_v0568,885,917 - 69,079,834 (+)NCBI
PanPan1.1573,928,078 - 74,123,570 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003811026 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008130
  ENSPPAP00000008130.1
RefSeq Acc Id: XP_003811026   ⟸   XM_003810978
- UniProtKB: A0A2R8ZU96 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000008130   ⟸   ENSPPAT00000030765
Protein Domains
Phosphatidylinositol-specific phospholipase C X


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027307 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030765.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.190 UniProtKB/TrEMBL
InterPro PI-PLC_domain UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLCXD1/2/3 UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
KEGG Report pps:100978650 UniProtKB/TrEMBL
NCBI Gene PLCXD3 ENTREZGENE
PANTHER PI-PLC X DOMAIN-CONTAINING PROTEIN 3 UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam PI-PLC-X UniProtKB/TrEMBL
PROSITE PIPLC_X_DOMAIN UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
Superfamily-SCOP SSF51695 UniProtKB/TrEMBL
UniProt A0A2R8ZU96 ENTREZGENE, UniProtKB/TrEMBL