NECTIN4 (nectin cell adhesion molecule 4) - Rat Genome Database

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Gene: NECTIN4 (nectin cell adhesion molecule 4) Pan paniscus
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Symbol: NECTIN4
Name: nectin cell adhesion molecule 4
RGD ID: 11876579
Description: ENCODES a protein that exhibits identical protein binding (inferred); receptor ligand activity (inferred); INVOLVED IN cell adhesion (inferred); heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (inferred); homophilic cell adhesion via plasma membrane adhesion molecules (inferred); ASSOCIATED WITH autoimmune interstitial lung, joint, and kidney disease (ortholog); Ectodermal Dysplasia-Syndactyly Syndrome 1 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN adherens junction (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nectin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,762,669 - 88,781,005 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,452,726 - 88,471,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,484,235 - 136,502,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,396,347 - 140,415,606 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,397,817 - 140,414,897 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NECTIN4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2188,762,669 - 88,781,005 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1188,452,726 - 88,471,340 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01136,484,235 - 136,502,478 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11140,396,347 - 140,415,606 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1140,397,817 - 140,414,897 (-)Ensemblpanpan1.1panPan2
NECTIN4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381161,070,998 - 161,089,558 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1161,070,998 - 161,089,558 (-)EnsemblGRCh38hg38GRCh38
GRCh371161,040,788 - 161,059,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361159,308,120 - 159,325,966 (-)NCBINCBI36Build 36hg18NCBI36
Build 341157,854,568 - 157,872,415NCBI
Celera1134,107,964 - 134,126,560 (-)NCBICelera
Cytogenetic Map1q23.3NCBI
HuRef1132,398,195 - 132,416,810 (-)NCBIHuRef
CHM1_11162,437,025 - 162,455,629 (-)NCBICHM1_1
T2T-CHM13v2.01160,208,489 - 160,227,037 (-)NCBIT2T-CHM13v2.0
Nectin4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391171,197,741 - 171,215,855 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1171,197,667 - 171,216,166 (+)EnsemblGRCm39 Ensembl
GRCm381171,370,173 - 171,388,287 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1171,370,099 - 171,388,598 (+)EnsemblGRCm38mm10GRCm38
MGSCv371173,300,304 - 173,318,418 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361173,207,073 - 173,225,273 (+)NCBIMGSCv36mm8
Celera1173,821,772 - 173,839,427 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map179.37NCBI
Nectin4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81386,335,027 - 86,354,152 (+)NCBIGRCr8
mRatBN7.21383,802,589 - 83,821,711 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1383,803,184 - 83,821,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1386,308,949 - 86,327,473 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01387,707,160 - 87,725,681 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01384,942,920 - 84,961,475 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01389,755,665 - 89,774,185 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1389,755,845 - 89,774,378 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01394,383,248 - 94,402,000 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41387,275,975 - 87,294,493 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1383,433,644 - 83,452,162 (+)NCBICelera
Cytogenetic Map13q24NCBI
Nectin4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546812,841,369 - 12,858,329 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546812,841,369 - 12,858,331 (-)NCBIChiLan1.0ChiLan1.0
NECTIN4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13821,378,144 - 21,392,419 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3821,375,556 - 21,392,632 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3821,452,164 - 21,466,905 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03821,487,177 - 21,512,187 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3821,490,338 - 21,512,183 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13821,384,036 - 21,398,772 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03821,798,014 - 21,812,724 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03822,207,287 - 22,222,026 (+)NCBIUU_Cfam_GSD_1.0
Nectin4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050587,171,818 - 7,189,734 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936903381,424 - 398,350 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936903381,383 - 398,339 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NECTIN4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl489,355,407 - 89,374,358 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1489,356,935 - 89,374,358 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2497,211,258 - 97,227,217 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NECTIN4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1202,890,082 - 2,910,271 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl202,891,603 - 2,919,915 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660381,938,908 - 1,957,897 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nectin4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624794281,675 - 299,324 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624794281,769 - 299,240 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000057046   ⟹   ENSPPAP00000034165
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,397,817 - 140,414,897 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000057048   ⟹   ENSPPAP00000034167
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1140,398,049 - 140,407,413 (-)Ensembl
RefSeq Acc Id: XM_034938712   ⟹   XP_034794603
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2188,762,669 - 88,781,005 (+)NCBI
NHGRI_mPanPan1188,452,726 - 88,471,340 (+)NCBI
Mhudiblu_PPA_v01136,484,235 - 136,502,040 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034794603 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034165.1
  ENSPPAP00000034167.1
RefSeq Acc Id: XP_034794603   ⟸   XM_034938712
- UniProtKB: A0A2R9C092 (UniProtKB/TrEMBL),   A0A2R9BWV9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000034165   ⟸   ENSPPAT00000057046
Ensembl Acc Id: ENSPPAP00000034167   ⟸   ENSPPAT00000057048
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039929 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057046.1 UniProtKB/TrEMBL
  ENSPPAT00000057048.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgC1_2_Nectin-3-4-like UniProtKB/TrEMBL
  Nectin/Nectin-like UniProtKB/TrEMBL
NCBI Gene NECTIN4 ENTREZGENE
PANTHER NECTIN-RELATED UniProtKB/TrEMBL
  PTHR23277:SF11 UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9BWV9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C092 ENTREZGENE, UniProtKB/TrEMBL