NAPRT (nicotinate phosphoribosyltransferase) - Rat Genome Database

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Gene: NAPRT (nicotinate phosphoribosyltransferase) Pan paniscus
Analyze
Symbol: NAPRT (Ensembl: EEF1D)
Name: nicotinate phosphoribosyltransferase (Ensembl:eukaryotic translation elongation factor 1 delta)
RGD ID: 11843911
Description: ENCODES a protein that exhibits nicotinate phosphoribosyltransferase activity (ortholog); INVOLVED IN NAD biosynthetic process (ortholog); response to oxidative stress (ortholog); PARTICIPATES IN nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); holoprosencephaly (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); eukaryotic translation elongation factor 1 complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NAPRT1; nicotinate phosphoribosyltransferase domain containing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,058,197 - 161,062,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,575,884 - 136,579,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,328,119 - 140,331,972 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,343,280 - 143,347,347 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,340,928 - 143,362,971 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NAPRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,058,197 - 161,062,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,575,884 - 136,579,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,328,119 - 140,331,972 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,343,280 - 143,347,347 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,340,928 - 143,362,971 (-)Ensemblpanpan1.1panPan2
NAPRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,572,874 - 143,578,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,574,785 - 143,578,649 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,656,955 - 144,660,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,728,098 - 144,731,636 (-)NCBINCBI36Build 36hg18NCBI36
Celera8140,967,186 - 140,970,744 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,908,475 - 139,912,033 (-)NCBIHuRef
CHM1_18144,697,179 - 144,700,655 (-)NCBICHM1_1
T2T-CHM13v2.08144,723,979 - 144,727,726 (-)NCBIT2T-CHM13v2.0
Naprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,762,812 - 75,766,330 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,762,805 - 75,766,330 (-)EnsemblGRCm39 Ensembl
GRCm381575,890,963 - 75,894,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,890,956 - 75,894,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,721,394 - 75,724,911 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,718,219 - 75,721,736 (-)NCBIMGSCv36mm8
Celera1577,391,944 - 77,395,461 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.05NCBI
Naprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,457,328 - 109,460,817 (-)NCBIGRCr8
mRatBN7.27107,576,645 - 107,580,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,576,627 - 107,580,102 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,316,156 - 109,319,613 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,539,834 - 111,543,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,485,758 - 111,489,215 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,922,979 - 116,926,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,922,944 - 116,926,555 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,814,946 - 116,818,403 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,865,273 - 113,868,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17113,899,517 - 113,902,960 (-)NCBI
Celera7103,933,643 - 103,937,100 (-)NCBICelera
Cytogenetic Map7q34NCBI
Naprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,280,223 - 2,283,613 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,280,223 - 2,283,613 (-)NCBIChiLan1.0ChiLan1.0
NAPRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,235,985 - 37,239,261 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,235,045 - 37,239,224 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,192,494 - 37,195,827 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,707,832 - 37,711,165 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,707,854 - 37,712,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,382,167 - 37,385,501 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,499,120 - 37,502,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,980,305 - 37,983,640 (-)NCBIUU_Cfam_GSD_1.0
Naprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,128,622 - 1,131,790 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,554,641 - 8,557,919 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,554,739 - 8,557,889 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAPRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4983,423 - 986,748 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14983,428 - 986,750 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NAPRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,794,933 - 137,799,145 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,792,993 - 137,798,658 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,094,565 - 2,098,729 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003819451   ⟹   XP_003819499
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,035 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,499 (-)NCBI
Mhudiblu_PPA_v08140,328,119 - 140,331,727 (-)NCBI
PanPan1.18143,343,280 - 143,347,347 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034966806   ⟹   XP_034822697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,044 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,725 (-)NCBI
Mhudiblu_PPA_v08140,328,119 - 140,331,731 (-)NCBI
RefSeq Acc Id: XM_034966807   ⟹   XP_034822698
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,047 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,728 (-)NCBI
Mhudiblu_PPA_v08140,328,119 - 140,331,966 (-)NCBI
RefSeq Acc Id: XM_034966808   ⟹   XP_034822699
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,041 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,500 (-)NCBI
Mhudiblu_PPA_v08140,328,121 - 140,331,729 (-)NCBI
RefSeq Acc Id: XM_034966809   ⟹   XP_034822700
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,049 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,730 (-)NCBI
Mhudiblu_PPA_v08140,328,119 - 140,331,967 (-)NCBI
RefSeq Acc Id: XM_034966810   ⟹   XP_034822701
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,038 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,499 (-)NCBI
Mhudiblu_PPA_v08140,328,121 - 140,331,728 (-)NCBI
RefSeq Acc Id: XM_034966811   ⟹   XP_034822702
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,053 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,734 (-)NCBI
Mhudiblu_PPA_v08140,328,119 - 140,331,972 (-)NCBI
RefSeq Acc Id: XM_055117080   ⟹   XP_054973055
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,045 (-)NCBI
NHGRI_mPanPan18136,575,884 - 136,579,500 (-)NCBI
RefSeq Acc Id: XM_063606969   ⟹   XP_063463039
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v27161,058,197 - 161,062,043 (-)NCBI
RefSeq Acc Id: XP_003819499   ⟸   XM_003819451
- Peptide Label: isoform X5
- UniProtKB: A0A2R8ZPA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034822702   ⟸   XM_034966811
- Peptide Label: isoform X8
RefSeq Acc Id: XP_034822700   ⟸   XM_034966809
- Peptide Label: isoform X6
RefSeq Acc Id: XP_034822698   ⟸   XM_034966807
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034822697   ⟸   XM_034966806
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034822699   ⟸   XM_034966808
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034822701   ⟸   XM_034966810
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054973055   ⟸   XM_055117080
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063463039   ⟸   XM_063606969
- Peptide Label: isoform X9
Protein Domains
Elongation factor 1 beta central acidic region   Nicotinate phosphoribosyltransferase C-terminal   Nicotinate phosphoribosyltransferase N-terminal   Translation elongation factor EF1B beta/delta


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000019348 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000021206.1 UniProtKB/TrEMBL
  ENSPPAT00000021220.1 UniProtKB/TrEMBL
  ENSPPAT00000021239.1 UniProtKB/TrEMBL
  ENSPPAT00000021289.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  3.30.70.60 UniProtKB/TrEMBL
  nicotinate phosphoribosyltransferase UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  eEF-1beta-like_sf UniProtKB/TrEMBL
  EF-1_beta_acid_region_euk UniProtKB/TrEMBL
  EF1B_bsu/dsu UniProtKB/TrEMBL
  EF1B_bsu/dsu_GNE UniProtKB/TrEMBL
  NAPRTase_C UniProtKB/TrEMBL
  NAPRTase_N UniProtKB/TrEMBL
  Nic_PRibTrfase-Fam UniProtKB/TrEMBL
  Nic_PRibTrfase_pncB UniProtKB/TrEMBL
  Nicotinate_pribotase-like_C UniProtKB/TrEMBL
  Transl_elong_EF1B/ribosomal_S6 UniProtKB/TrEMBL
  Transl_elong_EF1B_B/D_CS UniProtKB/TrEMBL
KEGG Report pps:100973528 UniProtKB/TrEMBL
NCBI Gene NAPRT ENTREZGENE
PANTHER EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER UniProtKB/TrEMBL
  ELONGATION FACTOR 1-DELTA UniProtKB/TrEMBL
  NICOTINATE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  PTHR11098 UniProtKB/TrEMBL
Pfam EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
  NAPRTase_C UniProtKB/TrEMBL
  NAPRTase_N UniProtKB/TrEMBL
PIRSF NAPRT UniProtKB/TrEMBL
PROSITE EF1BD_1 UniProtKB/TrEMBL
SMART EF-1_beta_acid UniProtKB/TrEMBL
  EF1_GNE UniProtKB/TrEMBL
Superfamily-SCOP Nicotinate/Quinolinate PRTase N-terminal domain-like UniProtKB/TrEMBL
  SSF51690 UniProtKB/TrEMBL
  SSF54984 UniProtKB/TrEMBL
UniProt A0A2R8ZI44_PANPA UniProtKB/TrEMBL
  A0A2R8ZL44_PANPA UniProtKB/TrEMBL
  A0A2R8ZL63_PANPA UniProtKB/TrEMBL
  A0A2R8ZPA0 ENTREZGENE, UniProtKB/TrEMBL