NAPRT (nicotinate phosphoribosyltransferase) - Rat Genome Database

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Gene: NAPRT (nicotinate phosphoribosyltransferase) Canis lupus familiaris
Analyze
Symbol: NAPRT
Name: nicotinate phosphoribosyltransferase
RGD ID: 12201080
Description: ENCODES a protein that exhibits nicotinate phosphoribosyltransferase activity (ortholog); INVOLVED IN NAD biosynthetic process (ortholog); PARTICIPATES IN nicotinamide adenine dinucleotide biosynthesis, the salvage pathway; ASSOCIATED WITH Brown-Vialetto-Van Laere syndrome 2 (ortholog); epidermolysis bullosa simplex with muscular dystrophy (ortholog); holoprosencephaly (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NAPRT1; nicotinate phosphoribosyltransferase domain containing 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,235,985 - 37,239,261 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,235,045 - 37,239,224 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,192,494 - 37,195,827 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,707,832 - 37,711,165 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,707,854 - 37,712,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,382,167 - 37,385,501 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,499,120 - 37,502,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,980,305 - 37,983,640 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
NAPRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11337,235,985 - 37,239,261 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1337,235,045 - 37,239,224 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1337,192,494 - 37,195,827 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01337,707,832 - 37,711,165 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1337,707,854 - 37,712,418 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11337,382,167 - 37,385,501 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01337,499,120 - 37,502,451 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01337,980,305 - 37,983,640 (-)NCBIUU_Cfam_GSD_1.0
NAPRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388143,572,874 - 143,578,330 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8143,574,785 - 143,578,649 (-)EnsemblGRCh38hg38GRCh38
GRCh378144,656,955 - 144,660,500 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,728,098 - 144,731,636 (-)NCBINCBI36Build 36hg18NCBI36
Celera8140,967,186 - 140,970,744 (-)NCBICelera
Cytogenetic Map8q24.3NCBI
HuRef8139,908,475 - 139,912,033 (-)NCBIHuRef
CHM1_18144,697,179 - 144,700,655 (-)NCBICHM1_1
T2T-CHM13v2.08144,723,979 - 144,727,726 (-)NCBIT2T-CHM13v2.0
Naprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391575,762,812 - 75,766,330 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1575,762,805 - 75,766,330 (-)EnsemblGRCm39 Ensembl
GRCm381575,890,963 - 75,894,481 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1575,890,956 - 75,894,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv371575,721,394 - 75,724,911 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361575,718,219 - 75,721,736 (-)NCBIMGSCv36mm8
Celera1577,391,944 - 77,395,461 (-)NCBICelera
Cytogenetic Map15D3NCBI
cM Map1535.05NCBI
Naprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87109,457,328 - 109,460,817 (-)NCBIGRCr8
mRatBN7.27107,576,645 - 107,580,102 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7107,576,627 - 107,580,102 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7109,316,156 - 109,319,613 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07111,539,834 - 111,543,291 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07111,485,758 - 111,489,215 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07116,922,979 - 116,926,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7116,922,944 - 116,926,555 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07116,814,946 - 116,818,403 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47113,865,273 - 113,868,730 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17113,899,517 - 113,902,960 (-)NCBI
Celera7103,933,643 - 103,937,100 (-)NCBICelera
Cytogenetic Map7q34NCBI
Naprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554542,280,223 - 2,283,613 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554542,280,223 - 2,283,613 (-)NCBIChiLan1.0ChiLan1.0
NAPRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27161,058,197 - 161,062,053 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18136,575,884 - 136,579,734 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08140,328,119 - 140,331,972 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18143,343,280 - 143,347,347 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8143,340,928 - 143,362,971 (-)Ensemblpanpan1.1panPan2
Naprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244053031,128,622 - 1,131,790 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364708,554,641 - 8,557,919 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364708,554,739 - 8,557,889 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAPRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4983,423 - 986,748 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14983,428 - 986,750 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NAPRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18137,794,933 - 137,799,145 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8137,792,993 - 137,798,658 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660392,094,565 - 2,098,729 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in NAPRT
47 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_038429630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038429633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038493445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038493446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038493447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038555743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038555744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038555745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038619646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038619647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038619648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038685257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_846661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005298424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005335135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005368910 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005403197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005436639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCAFT00000047889   ⟹   ENSCAFP00000040247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1337,235,045 - 37,239,224 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000084336   ⟹   ENSCAFP00000043311
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1337,236,939 - 37,239,224 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845027542   ⟹   ENSCAFP00845021669
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1337,707,854 - 37,712,418 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845027590   ⟹   ENSCAFP00845021709
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1337,707,854 - 37,711,412 (-)Ensembl
RefSeq Acc Id: XM_038429630   ⟹   XP_038285558
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1337,192,494 - 37,195,826 (-)NCBI
RefSeq Acc Id: XM_038429633   ⟹   XP_038285561
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1337,192,527 - 37,194,960 (-)NCBI
RefSeq Acc Id: XM_038493445   ⟹   XP_038349373
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,382,192 - 37,385,499 (-)NCBI
RefSeq Acc Id: XM_038493446   ⟹   XP_038349374
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,382,167 - 37,385,500 (-)NCBI
RefSeq Acc Id: XM_038493447   ⟹   XP_038349375
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,382,200 - 37,384,634 (-)NCBI
RefSeq Acc Id: XM_038555743   ⟹   XP_038411671
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01337,980,330 - 37,983,638 (-)NCBI
RefSeq Acc Id: XM_038555744   ⟹   XP_038411672
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01337,980,305 - 37,983,639 (-)NCBI
RefSeq Acc Id: XM_038555745   ⟹   XP_038411673
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01337,980,338 - 37,982,773 (-)NCBI
RefSeq Acc Id: XM_038619646   ⟹   XP_038475574
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,499,145 - 37,502,449 (-)NCBI
RefSeq Acc Id: XM_038619647   ⟹   XP_038475575
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,499,120 - 37,502,450 (-)NCBI
RefSeq Acc Id: XM_038619648   ⟹   XP_038475576
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,499,153 - 37,501,583 (-)NCBI
RefSeq Acc Id: XM_038685255   ⟹   XP_038541183
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01337,707,857 - 37,711,163 (-)NCBI
RefSeq Acc Id: XM_038685256   ⟹   XP_038541184
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01337,707,832 - 37,711,164 (-)NCBI
RefSeq Acc Id: XM_038685257   ⟹   XP_038541185
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01337,707,865 - 37,710,298 (-)NCBI
RefSeq Acc Id: XM_846661   ⟹   XP_851754
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11337,235,985 - 37,239,261 (-)NCBI
Dog10K_Boxer_Tasha1337,192,519 - 37,195,825 (-)NCBI
Sequence:
RefSeq Acc Id: XR_005298424
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1337,192,585 - 37,195,827 (-)NCBI
RefSeq Acc Id: XR_005335135
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11337,382,258 - 37,385,501 (-)NCBI
RefSeq Acc Id: XR_005368910
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01337,980,396 - 37,983,640 (-)NCBI
RefSeq Acc Id: XR_005403197
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01337,499,211 - 37,502,451 (-)NCBI
RefSeq Acc Id: XR_005436639
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01337,707,923 - 37,711,165 (-)NCBI
RefSeq Acc Id: XP_851754   ⟸   XM_846661
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L4R4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCAFP00000043311   ⟸   ENSCAFT00000084336
Ensembl Acc Id: ENSCAFP00000040247   ⟸   ENSCAFT00000047889
RefSeq Acc Id: XP_038349374   ⟸   XM_038493446
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038349373   ⟸   XM_038493445
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038349375   ⟸   XM_038493447
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038475575   ⟸   XM_038619647
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038475574   ⟸   XM_038619646
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038475576   ⟸   XM_038619648
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038541184   ⟸   XM_038685256
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038541183   ⟸   XM_038685255
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L4R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038541185   ⟸   XM_038685257
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038285558   ⟸   XM_038429630
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038285561   ⟸   XM_038429633
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038411672   ⟸   XM_038555744
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038411671   ⟸   XM_038555743
- Peptide Label: isoform X1
- UniProtKB: A0A8C0L4R4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038411673   ⟸   XM_038555745
- Peptide Label: isoform X3
Ensembl Acc Id: ENSCAFP00845021669   ⟸   ENSCAFT00845027542
Ensembl Acc Id: ENSCAFP00845021709   ⟸   ENSCAFT00845027590
Protein Domains
Nicotinate phosphoribosyltransferase C-terminal   Nicotinate phosphoribosyltransferase N-terminal

Promoters
RGD ID:13685619
Promoter ID:EPDNEW_C3688
Type:initiation region
Name:NAPRT_1
Description:nicotinate phosphoribosyltransferase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11337,239,248 - 37,239,308EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031759 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030024070 UniProtKB/TrEMBL
  ENSCAFG00040011823 UniProtKB/TrEMBL
  ENSCAFG00845015437 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000047889.3 UniProtKB/TrEMBL
  ENSCAFT00000084336.2 UniProtKB/TrEMBL
  ENSCAFT00030044275.1 UniProtKB/TrEMBL
  ENSCAFT00040021835.1 UniProtKB/TrEMBL
  ENSCAFT00845027542 ENTREZGENE
  ENSCAFT00845027542.1 UniProtKB/TrEMBL
  ENSCAFT00845027590.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
  nicotinate phosphoribosyltransferase UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  NAPRTase_C UniProtKB/TrEMBL
  NAPRTase_N UniProtKB/TrEMBL
  Nic_PRibTrfase-Fam UniProtKB/TrEMBL
  Nic_PRibTrfase_pncB UniProtKB/TrEMBL
  Nicotinate_pribotase-like_C UniProtKB/TrEMBL
NCBI Gene NAPRT ENTREZGENE
PANTHER NICOTINATE PHOSPHORIBOSYLTRANSFERASE UniProtKB/TrEMBL
  PTHR11098 UniProtKB/TrEMBL
Pfam NAPRTase_C UniProtKB/TrEMBL
  NAPRTase_N UniProtKB/TrEMBL
Superfamily-SCOP Nicotinate/Quinolinate PRTase N-terminal domain-like UniProtKB/TrEMBL
  SSF51690 UniProtKB/TrEMBL
UniProt A0A8C0L4R4 ENTREZGENE
  A0A8C0PBL9_CANLF UniProtKB/TrEMBL
  A0A8I3NS26_CANLF UniProtKB/TrEMBL
  A0A8I3P074_CANLF UniProtKB/TrEMBL
  A0A8P0SWQ6_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:43623 ENTREZGENE