PADI2 (peptidyl arginine deiminase 2) - Rat Genome Database

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Gene: PADI2 (peptidyl arginine deiminase 2) Pan paniscus
Analyze
Symbol: PADI2
Name: peptidyl arginine deiminase 2
RGD ID: 11843408
Description: ENCODES a protein that exhibits calcium ion binding (inferred); histone arginine deiminase activity (inferred); histone H3R26 arginine deiminase activity (inferred); INVOLVED IN cellular response to leukemia inhibitory factor (ortholog); substantia nigra development (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); COVID-19 (ortholog); gastrointestinal stromal tumor (ortholog); FOUND IN cytoplasm (inferred); euchromatin (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-arginine deiminase type-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,009,732 - 210,062,423 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,128,609 - 209,181,304 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,011,708 - 16,064,344 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,067,729 - 17,120,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,067,729 - 17,120,513 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PADI2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21210,009,732 - 210,062,423 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11209,128,609 - 209,181,304 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,011,708 - 16,064,344 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,067,729 - 17,120,513 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,067,729 - 17,120,513 (-)Ensemblpanpan1.1panPan2
PADI2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,066,761 - 17,119,451 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,066,761 - 17,119,451 (-)EnsemblGRCh38hg38GRCh38
GRCh37117,393,256 - 17,445,946 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,265,843 - 17,318,535 (-)NCBINCBI36Build 36hg18NCBI36
Build 34117,140,558 - 17,191,236NCBI
Celera115,715,602 - 15,768,303 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,637,268 - 15,689,337 (-)NCBIHuRef
CHM1_1117,501,602 - 17,554,329 (-)NCBICHM1_1
T2T-CHM13v2.0116,877,198 - 16,929,905 (-)NCBIT2T-CHM13v2.0
Padi2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,633,685 - 140,679,897 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,633,655 - 140,679,897 (+)EnsemblGRCm39 Ensembl
GRCm384140,906,336 - 140,952,586 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,906,344 - 140,952,586 (+)EnsemblGRCm38mm10GRCm38
MGSCv374140,462,275 - 140,508,501 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364138,644,091 - 138,693,178 (+)NCBIMGSCv36mm8
MGSCv364140,178,503 - 140,224,662 (+)NCBIMGSCv36mm8
Celera4142,714,994 - 142,753,117 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.01NCBI
Padi2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,492,087 - 158,534,662 (+)NCBIGRCr8
mRatBN7.25153,209,053 - 153,251,632 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,209,053 - 153,251,632 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,898,744 - 155,940,735 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,672,018 - 157,714,009 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,661,096 - 157,703,184 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,428,479 - 159,471,113 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,428,515 - 159,471,144 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05163,141,202 - 163,183,775 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,762,824 - 159,805,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,773,011 - 159,815,587 (+)NCBI
Celera5151,567,606 - 151,616,600 (+)NCBICelera
Cytogenetic Map5q36NCBI
Padi2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,709,444 - 1,752,783 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,709,307 - 1,751,332 (+)NCBIChiLan1.0ChiLan1.0
PADI2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1281,116,031 - 81,147,889 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl281,116,140 - 81,145,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,641,018 - 77,685,332 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,749,888 - 81,794,334 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,749,859 - 81,794,317 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,502,939 - 78,547,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,519,889 - 79,564,357 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,588,375 - 80,632,825 (+)NCBIUU_Cfam_GSD_1.0
Padi2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,210,290 - 38,236,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,033,230 - 4,088,256 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,033,703 - 4,066,468 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,696,481 - 75,755,890 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,696,476 - 75,755,977 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,039,608 - 70,099,180 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PADI2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,465,098 - 115,520,772 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,465,338 - 115,520,828 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033596,810 - 650,559 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Padi2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,693,060 - 2,734,107 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,693,276 - 2,734,070 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057893   ⟹   ENSPPAP00000035008
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl117,067,729 - 17,120,513 (-)Ensembl
RefSeq Acc Id: XM_003814448   ⟹   XP_003814496
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21210,009,732 - 210,062,423 (+)NCBI
NHGRI_mPanPan11209,128,609 - 209,181,304 (+)NCBI
Mhudiblu_PPA_v0116,011,708 - 16,064,344 (-)NCBI
PanPan1.1117,067,729 - 17,120,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034956578   ⟹   XP_034812469
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21210,009,790 - 210,062,423 (+)NCBI
NHGRI_mPanPan11209,128,668 - 209,181,304 (+)NCBI
Mhudiblu_PPA_v0116,011,708 - 16,064,344 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003814496 (Get FASTA)   NCBI Sequence Viewer  
  XP_034812469 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035008
  ENSPPAP00000035008.1
Reference Protein Sequences
RefSeq Acc Id: XP_003814496   ⟸   XM_003814448
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034812469   ⟸   XM_034956578
- Peptide Label: isoform X1
RefSeq Acc Id: ENSPPAP00000035008   ⟸   ENSPPAT00000057893
Protein Domains
Protein-arginine deiminase (PAD) central   Protein-arginine deiminase (PAD) N-terminal   Protein-arginine deiminase C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040328 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057893.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1700 UniProtKB/TrEMBL
  2.60.40.1860 UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/TrEMBL
  PAD UniProtKB/TrEMBL
  PAD_C UniProtKB/TrEMBL
  PAD_central_sf UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
  PAD_N_sf UniProtKB/TrEMBL
  Prot_Arg_deaminase_cen_dom UniProtKB/TrEMBL
KEGG Report pps:100989222 UniProtKB/TrEMBL
NCBI Gene PADI2 ENTREZGENE
PANTHER PROTEIN-ARGININE DEIMINASE TYPE-2 UniProtKB/TrEMBL
  PTHR10837 UniProtKB/TrEMBL
Pfam PAD UniProtKB/TrEMBL
  PAD_M UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
PIRSF Protein-arginine_deiminase UniProtKB/TrEMBL
Superfamily-SCOP Pentein UniProtKB/TrEMBL
  SSF110083 UniProtKB/TrEMBL
  SSF49503 UniProtKB/TrEMBL
UniProt A0A2R9BZA0 ENTREZGENE, UniProtKB/TrEMBL