NEU3 (neuraminidase 3) - Rat Genome Database

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Gene: NEU3 (neuraminidase 3) Pan paniscus
Analyze
Symbol: NEU3
Name: neuraminidase 3
RGD ID: 11796759
Description: ENCODES a protein that exhibits alpha-sialidase activity (inferred); exo-alpha-sialidase activity (inferred); hydrolase activity, acting on glycosyl bonds (inferred); INVOLVED IN carbohydrate metabolic process (ortholog); PARTICIPATES IN Fabry disease pathway; Gaucher's disease pathway; Krabbe disease pathway; ASSOCIATED WITH 3-methylglutaconic aciduria type 7b (ortholog); intellectual disability (ortholog); Marfanoid Mental Retardation Syndrome, Autosomal (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sialidase-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2975,918,466 - 75,940,916 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11176,961,185 - 76,983,624 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01170,047,878 - 70,070,303 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11173,353,332 - 73,373,270 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,353,332 - 73,373,270 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NEU3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2975,918,466 - 75,940,916 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11176,961,185 - 76,983,624 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01170,047,878 - 70,070,303 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11173,353,332 - 73,373,270 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1173,353,332 - 73,373,270 (+)Ensemblpanpan1.1panPan2
NEU3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381174,980,515 - 75,020,676 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1174,988,279 - 75,018,893 (+)EnsemblGRCh38hg38GRCh38
GRCh371174,699,689 - 74,721,952 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361174,377,598 - 74,396,391 (+)NCBINCBI36Build 36hg18NCBI36
Build 341174,376,826 - 74,396,389NCBI
Celera1172,006,517 - 72,025,314 (+)NCBICelera
Cytogenetic Map11q13.4NCBI
HuRef1170,996,749 - 71,016,487 (+)NCBIHuRef
CHM1_11174,583,347 - 74,602,139 (+)NCBICHM1_1
T2T-CHM13v2.01174,910,079 - 74,957,510 (+)NCBIT2T-CHM13v2.0
Neu3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39799,460,646 - 99,477,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl799,460,646 - 99,477,624 (-)EnsemblGRCm39 Ensembl
GRCm38799,811,434 - 99,828,457 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,811,439 - 99,828,417 (-)EnsemblGRCm38mm10GRCm38
MGSCv377106,959,949 - 106,976,927 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36799,685,522 - 99,702,500 (-)NCBIMGSCv36mm8
Celera7100,136,642 - 100,153,663 (-)NCBICelera
Cytogenetic Map7E1NCBI
cM Map754.15NCBI
Neu3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81163,549,834 - 163,560,997 (-)NCBIGRCr8
mRatBN7.21154,137,732 - 154,148,879 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1154,050,855 - 154,148,813 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1162,132,680 - 162,143,804 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01169,312,813 - 169,323,937 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01162,186,360 - 162,197,489 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01164,803,574 - 164,814,777 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1164,803,574 - 164,814,651 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,006,216 - 171,017,255 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41157,172,027 - 157,183,064 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11157,250,432 - 157,261,470 (-)NCBI
Celera1152,223,019 - 152,234,091 (-)NCBICelera
Cytogenetic Map1q32NCBI
Neu3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541416,788,171 - 16,798,535 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541416,783,996 - 16,798,368 (-)NCBIChiLan1.0ChiLan1.0
NEU3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12123,456,424 - 23,484,872 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2123,213,985 - 23,250,034 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02123,651,315 - 23,687,393 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2123,663,243 - 23,677,038 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12123,449,567 - 23,485,563 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02123,646,010 - 23,682,029 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02123,563,652 - 23,599,693 (-)NCBIUU_Cfam_GSD_1.0
Neu3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494762,297,867 - 62,315,348 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364983,897,485 - 3,910,115 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364983,897,511 - 3,915,013 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEU3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl99,315,334 - 9,334,918 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.199,315,263 - 9,333,878 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2910,407,329 - 10,423,135 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NEU3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,220,472 - 66,243,163 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604359,567,996 - 59,590,439 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Neu3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248172,107,893 - 2,133,626 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003814694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000059342   ⟹   ENSPPAP00000036450
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1173,353,332 - 73,373,270 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000059347   ⟹   ENSPPAP00000036455
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1173,353,833 - 73,370,279 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000059350   ⟹   ENSPPAP00000036458
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1173,353,833 - 73,370,080 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000059351   ⟹   ENSPPAP00000036459
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1173,353,833 - 73,354,810 (+)Ensembl
RefSeq Acc Id: XM_003814694   ⟹   XP_003814742
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2975,918,466 - 75,940,916 (+)NCBI
NHGRI_mPanPan11176,961,185 - 76,983,624 (+)NCBI
Mhudiblu_PPA_v01170,047,878 - 70,070,303 (+)NCBI
PanPan1.11173,353,332 - 73,373,270 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003814742 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000036450.1
  ENSPPAP00000036455.1
  ENSPPAP00000036458.1
  ENSPPAP00000036459.1
RefSeq Acc Id: XP_003814742   ⟸   XM_003814694
- Sequence:
Ensembl Acc Id: ENSPPAP00000036450   ⟸   ENSPPAT00000059342
Ensembl Acc Id: ENSPPAP00000036455   ⟸   ENSPPAT00000059347
Ensembl Acc Id: ENSPPAP00000036459   ⟸   ENSPPAT00000059351
Ensembl Acc Id: ENSPPAP00000036458   ⟸   ENSPPAT00000059350
Protein Domains
Sialidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040988 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059342.1 UniProtKB/TrEMBL
  ENSPPAT00000059347.1 UniProtKB/TrEMBL
  ENSPPAT00000059350.1 UniProtKB/TrEMBL
  ENSPPAT00000059351.1 UniProtKB/TrEMBL
Gene3D-CATH 2.120.10.10 UniProtKB/TrEMBL
InterPro Sialidase UniProtKB/TrEMBL
  Sialidase_fam UniProtKB/TrEMBL
  Sialidase_sf UniProtKB/TrEMBL
NCBI Gene NEU3 ENTREZGENE
PANTHER PTHR10628 UniProtKB/TrEMBL
  PTHR10628:SF23 UniProtKB/TrEMBL
Pfam BNR_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF50939 UniProtKB/TrEMBL
UniProt A0A2R9C3E9_PANPA UniProtKB/TrEMBL
  A0A2R9C3F3_PANPA UniProtKB/TrEMBL
  A0A2R9C3V9_PANPA UniProtKB/TrEMBL
  A0A2R9C6D9_PANPA UniProtKB/TrEMBL