GFI1 (growth factor independent 1 transcriptional repressor) - Rat Genome Database

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Gene: GFI1 (growth factor independent 1 transcriptional repressor) Pan paniscus
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Symbol: GFI1
Name: growth factor independent 1 transcriptional repressor
RGD ID: 11776627
Description: ENCODES a protein that exhibits DNA-binding transcription repressor activity (ortholog); INVOLVED IN cell fate commitment (ortholog); cell fate specification (ortholog); inner ear auditory receptor cell differentiation (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Diamond-Blackfan anemia (ortholog); Gastro-Enteropancreatic Neuroendocrine Tumor (ortholog); FOUND IN nuclear body (inferred); nuclear matrix (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger protein Gfi-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21134,538,355 - 134,547,424 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11133,689,661 - 133,703,553 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,139,171 - 95,151,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,875,880 - 93,883,558 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,876,245 - 93,883,528 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
GFI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21134,538,355 - 134,547,424 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11133,689,661 - 133,703,553 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0195,139,171 - 95,151,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,875,880 - 93,883,558 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,876,245 - 93,883,528 (-)Ensemblpanpan1.1panPan2
GFI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38192,473,043 - 92,486,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl192,473,043 - 92,486,925 (-)EnsemblGRCh38hg38GRCh38
GRCh37192,938,600 - 92,952,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36192,712,909 - 92,725,021 (-)NCBINCBI36Build 36hg18NCBI36
Build 34192,652,341 - 92,664,451NCBI
Celera191,193,179 - 91,205,211 (-)NCBICelera
Cytogenetic Map1p22.1NCBI
HuRef191,061,525 - 91,073,603 (-)NCBIHuRef
CHM1_1193,055,130 - 93,067,261 (-)NCBICHM1_1
T2T-CHM13v2.0192,317,932 - 92,331,836 (-)NCBIT2T-CHM13v2.0
Gfi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395107,864,521 - 107,873,671 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5107,864,523 - 107,873,902 (-)EnsemblGRCm39 Ensembl
GRCm385107,716,655 - 107,725,805 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5107,716,657 - 107,726,036 (-)EnsemblGRCm38mm10GRCm38
MGSCv375108,145,674 - 108,153,363 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365107,956,961 - 107,964,646 (-)NCBIMGSCv36mm8
Celera5104,829,261 - 104,836,969 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map552.23NCBI
Gfi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8142,185,489 - 2,204,191 (+)NCBIGRCr8
mRatBN7.2142,040,576 - 2,056,874 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl142,042,434 - 2,051,814 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx141,920,954 - 1,930,312 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0143,222,742 - 3,232,132 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0141,919,439 - 1,928,836 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0143,058,035 - 3,073,332 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl143,058,993 - 3,068,371 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0143,060,287 - 3,069,973 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,597,303 - 2,606,681 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,597,302 - 2,606,681 (+)NCBI
Celera142,061,330 - 2,070,708 (+)NCBICelera
RH 3.4 Map1437.2RGD
Cytogenetic Map14p22NCBI
Gfi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554232,022,417 - 2,033,149 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554232,024,084 - 2,032,530 (+)NCBIChiLan1.0ChiLan1.0
GFI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1656,473,032 - 56,484,422 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl656,256,305 - 56,484,422 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha659,174,527 - 59,183,663 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0656,849,754 - 56,861,112 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl656,852,003 - 56,861,112 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1656,531,815 - 56,540,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0656,510,728 - 56,519,864 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0656,970,884 - 56,980,018 (+)NCBIUU_Cfam_GSD_1.0
Gfi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405058102,328,318 - 102,337,410 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365376,610,565 - 6,618,450 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365376,610,565 - 6,618,509 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GFI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4124,621,261 - 124,629,638 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14124,619,887 - 124,629,638 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GFI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12040,771,238 - 40,786,008 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2040,776,816 - 40,783,717 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603377,232,569 - 77,242,841 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gfi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247425,261,537 - 5,270,695 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247425,260,651 - 5,271,908 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000061851   ⟹   ENSPPAP00000038942
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl193,876,245 - 93,883,528 (-)Ensembl
RefSeq Acc Id: XM_024930559   ⟹   XP_024786327
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21134,538,355 - 134,547,424 (+)NCBI
NHGRI_mPanPan11133,689,661 - 133,703,553 (+)NCBI
Mhudiblu_PPA_v0195,139,171 - 95,151,054 (-)NCBI
PanPan1.1193,875,880 - 93,883,558 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_024786327 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000038942.1
RefSeq Acc Id: XP_024786327   ⟸   XM_024930559
- Sequence:
Ensembl Acc Id: ENSPPAP00000038942   ⟸   ENSPPAT00000061851
Protein Domains
C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042186 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061851.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene GFI1 ENTREZGENE
PANTHER ZINC FINGER AND SCAN DOMAIN-CONTAINING UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 135-LIKE UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A2R9CLA9_PANPA UniProtKB/TrEMBL