USP3 (ubiquitin specific peptidase 3) - Rat Genome Database

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Gene: USP3 (ubiquitin specific peptidase 3) Pan paniscus
Analyze
Symbol: USP3
Name: ubiquitin specific peptidase 3
RGD ID: 11755700
Description: ENCODES a protein that exhibits promoter-specific chromatin binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN chromatin (inferred); cytoplasm (inferred); cytoplasmic ribonucleoprotein granule (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ubiquitin carboxyl-terminal hydrolase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21652,752,572 - 52,839,422 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11556,928,338 - 57,018,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01542,450,782 - 42,541,162 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11560,769,071 - 60,834,312 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,746,406 - 60,830,535 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
USP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21652,752,572 - 52,839,422 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11556,928,338 - 57,018,712 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01542,450,782 - 42,541,162 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11560,769,071 - 60,834,312 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1560,746,406 - 60,830,535 (+)Ensemblpanpan1.1panPan2
USP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381563,504,593 - 63,594,633 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1563,504,511 - 63,594,640 (+)EnsemblGRCh38hg38GRCh38
GRCh371563,796,792 - 63,886,832 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361561,583,863 - 61,670,716 (+)NCBINCBI36Build 36hg18NCBI36
Build 341561,583,862 - 61,670,714NCBI
Celera1540,676,343 - 40,763,066 (+)NCBICelera
Cytogenetic Map15q22.31NCBI
HuRef1540,621,287 - 40,711,268 (+)NCBIHuRef
CHM1_11563,915,941 - 64,006,065 (+)NCBICHM1_1
T2T-CHM13v2.01561,311,846 - 61,401,872 (+)NCBIT2T-CHM13v2.0
Usp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39966,421,573 - 66,501,996 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl966,421,919 - 66,500,424 (-)EnsemblGRCm39 Ensembl
GRCm38966,514,639 - 66,593,148 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl966,514,637 - 66,593,142 (-)EnsemblGRCm38mm10GRCm38
MGSCv37966,365,688 - 66,440,787 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36966,315,887 - 66,390,986 (-)NCBIMGSCv36mm8
Celera963,751,848 - 63,826,987 (-)NCBICelera
Cytogenetic Map9CNCBI
cM Map935.96NCBI
Usp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8875,973,278 - 76,049,151 (-)NCBIGRCr8
mRatBN7.2867,078,249 - 67,154,109 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl867,079,927 - 67,154,111 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx872,592,343 - 72,666,625 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0870,865,164 - 70,939,434 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0868,735,501 - 68,809,701 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0872,207,970 - 72,284,871 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl872,207,972 - 72,284,873 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0871,875,687 - 71,951,083 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4870,821,429 - 70,897,119 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1870,840,484 - 70,916,173 (-)NCBI
Celera866,465,505 - 66,539,503 (-)NCBICelera
Cytogenetic Map8q24NCBI
Usp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545011,727,104 - 11,802,462 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545011,729,433 - 11,802,462 (-)NCBIChiLan1.0ChiLan1.0
USP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13028,073,484 - 28,184,121 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3028,072,655 - 28,181,749 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3027,994,320 - 28,105,523 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03028,247,380 - 28,358,779 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3028,247,372 - 28,356,897 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13028,184,910 - 28,296,144 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03028,247,406 - 28,358,439 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03028,485,422 - 28,596,600 (+)NCBIUU_Cfam_GSD_1.0
Usp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640106,190,114 - 106,282,480 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647124,035,655 - 24,130,997 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647124,032,644 - 24,130,543 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1108,415,703 - 108,515,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11108,414,358 - 108,515,611 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
USP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12619,947,806 - 20,030,515 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2619,948,453 - 19,992,638 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048121,366,857 - 121,451,299 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247818,918,526 - 9,016,070 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247818,918,532 - 9,016,022 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057888   ⟹   ENSPPAP00000035003
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,746,406 - 60,830,535 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057892   ⟹   ENSPPAP00000035007
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,746,406 - 60,830,535 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057903   ⟹   ENSPPAP00000035018
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,770,148 - 60,830,535 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057907   ⟹   ENSPPAP00000035022
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,792,947 - 60,830,535 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057909   ⟹   ENSPPAP00000035024
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,793,009 - 60,830,535 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000057915   ⟹   ENSPPAP00000035030
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1560,796,437 - 60,830,535 (+)Ensembl
RefSeq Acc Id: XM_034938893   ⟹   XP_034794784
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,752,572 - 52,839,422 (+)NCBI
NHGRI_mPanPan11556,928,339 - 57,018,712 (+)NCBI
Mhudiblu_PPA_v01542,450,782 - 42,541,155 (+)NCBI
RefSeq Acc Id: XM_034938894   ⟹   XP_034794785
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,752,777 - 52,839,422 (+)NCBI
NHGRI_mPanPan11556,928,338 - 57,018,712 (+)NCBI
Mhudiblu_PPA_v01542,450,782 - 42,541,155 (+)NCBI
RefSeq Acc Id: XM_034938895   ⟹   XP_034794786
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,774,958 - 52,839,422 (+)NCBI
NHGRI_mPanPan11556,951,053 - 57,018,712 (+)NCBI
Mhudiblu_PPA_v01542,474,922 - 42,541,155 (+)NCBI
RefSeq Acc Id: XM_034938896   ⟹   XP_034794787
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,752,858 - 52,839,422 (+)NCBI
NHGRI_mPanPan11556,928,979 - 57,018,712 (+)NCBI
Mhudiblu_PPA_v01542,450,783 - 42,541,162 (+)NCBI
RefSeq Acc Id: XM_055098217   ⟹   XP_054954192
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,774,958 - 52,839,422 (+)NCBI
NHGRI_mPanPan11556,951,053 - 57,018,712 (+)NCBI
RefSeq Acc Id: XM_063596703   ⟹   XP_063452773
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21652,775,484 - 52,839,422 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034794785   ⟸   XM_034938894
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034794784   ⟸   XM_034938893
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BZ95 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034794787   ⟸   XM_034938896
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BZC7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034794786   ⟸   XM_034938895
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000035003   ⟸   ENSPPAT00000057888
RefSeq Acc Id: ENSPPAP00000035007   ⟸   ENSPPAT00000057892
RefSeq Acc Id: ENSPPAP00000035018   ⟸   ENSPPAT00000057903
RefSeq Acc Id: ENSPPAP00000035030   ⟸   ENSPPAT00000057915
RefSeq Acc Id: ENSPPAP00000035024   ⟸   ENSPPAT00000057909
RefSeq Acc Id: ENSPPAP00000035022   ⟸   ENSPPAT00000057907
RefSeq Acc Id: XP_054954192   ⟸   XM_055098217
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZB0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063452773   ⟸   XM_063596703
- Peptide Label: isoform X2
Protein Domains
UBP-type   USP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040233 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057888.1 UniProtKB/TrEMBL
  ENSPPAT00000057892.1 UniProtKB/TrEMBL
  ENSPPAT00000057903.1 UniProtKB/TrEMBL
  ENSPPAT00000057907.1 UniProtKB/TrEMBL
  ENSPPAT00000057909.1 UniProtKB/TrEMBL
  ENSPPAT00000057915.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene USP3 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 3 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PROSITE USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A2R9BZ95 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BZA8_PANPA UniProtKB/TrEMBL
  A0A2R9BZB0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BZC7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C2K1_PANPA UniProtKB/TrEMBL
  A0A2R9C9E7_PANPA UniProtKB/TrEMBL